TheraRadar

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Data updated: Mar 10, 2026

VEMLIDY

TENOFOVIR ALAFENAMIDE FUMARATE
Infectious Disease Approved 2016-11-10
7
Indications
--
Phase 3 Trials
2
Priority Reviews
9
Years on Market

Details

Status
Prescription
First Approved
2016-11-10
Routes
ORAL
Dosage Forms
TABLET

Companies

Active Ingredient: TENOFOVIR ALAFENAMIDE FUMARATE

VEMLIDY Approval History

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What VEMLIDY Treats

1 indications

VEMLIDY is approved for 1 conditions since its original approval in 2016. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Hepatitis B
Source: FDA Label

VEMLIDY Boxed Warning

POSTTREATMENT SEVERE ACUTE EXACERBATION OF HEPATITIS B Discontinuation of anti-hepatitis B therapy, including VEMLIDY, may result in severe acute exacerbations of hepatitis B. Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in patients who discontinue anti-hepatitis B therapy, including VEMLIDY. If appropriate, resumption of anti-hepatitis B therapy may be warranted [see Warnings and Precautions (5.1) ] . WARNING: POSTTREATMENT...

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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

VEMLIDY FDA Label Details

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Indications & Usage

FDA Label (PDF)

VEMLIDY is indicated for the treatment of chronic hepatitis B virus (HBV) infection in adults and pediatric patients 6 years of age and older and weighing at least 25 kg with compensated liver disease [see Clinical Studies ] . VEMLIDY is a hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitor and is indicated for the treatment of chronic hepatitis B virus infection in adults and pediatric patients 6 years of age and older and weighing at least 25 kg with compensated liver disease.

⚠️ BOXED WARNING

WARNING: POSTTREATMENT SEVERE ACUTE EXACERBATION OF HEPATITIS B Discontinuation of anti-hepatitis B therapy, including VEMLIDY, may result in severe acute exacerbations of hepatitis B. Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several month...

VEMLIDY Patents & Exclusivity

Latest Patent: Feb 2033

Patents (8 active)

US9296769*PED Expires Feb 15, 2033
US8754065*PED Expires Feb 15, 2033
US8754065 Expires Aug 15, 2032
US9296769 Expires Aug 15, 2032
Source: FDA Orange Book

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.