THAM
Details
- Status
- Prescription
- First Approved
- 1965-12-16
- Routes
- INJECTION
- Dosage Forms
- SOLUTION
THAM Approval History
What THAM Treats
2 indicationsTHAM is approved for 2 conditions since its original approval in 1965. These indications span multiple therapeutic areas including oncology, immunology, and more.
- Metabolic Acidosis
- Cardiac Arrest
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Active Pipeline
Ongoing clinical trials by development phase
Key Completed Trials
Completed studies with published results, ranked by significance
Trial Timeline
Full development history with FDA approval milestones
Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
THAM FDA Label Details
ProIndications & Usage
FDA Label (PDF)Tham Solution (tromethamine injection) is indicated for the prevention and correction of metabolic acidosis. In the following conditions it may help to sustain vital functions and thus provide time for treatment of the primary disease: Metabolic Acidosis Associated with Cardiac Bypass Surgery. Tham Solution has been found to be primarily beneficial in correcting metabolic acidosis which may occur during or immediately following cardiac bypass surgical procedures. Correction of Acidity of ACD Blood in Cardiac Bypass Surgery. It is well known that ACD blood is acidic and becomes more acidic on s...
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Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.