TheraRadar

Pharma Intelligence, Simplified

Data updated: Mar 10, 2026

GLIADEL

CARMUSTINE Alkylating Activity
Approved 1996-09-23
2
Indications
--
Phase 3 Trials
2
Priority Reviews
29
Years on Market

Details

Status
Prescription
First Approved
1996-09-23
Routes
INTRACRANIAL
Dosage Forms
IMPLANT

Companies

Active Ingredient: CARMUSTINE

GLIADEL Approval History

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What GLIADEL Treats

2 indications

GLIADEL is approved for 2 conditions since its original approval in 1996. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Glioma
  • Glioblastoma
Source: FDA Label
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

GLIADEL FDA Label Details

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Indications & Usage

FDA Label (PDF)

GLIADEL Wafer is indicated for the treatment of patients with: newly-diagnosed high-grade glioma as an adjunct to surgery and radiation, and recurrent glioblastoma as an adjunct to surgery. GLIADEL Wafer is an alkylating drug indicated for the treatment of: newly-diagnosed high-grade glioma as an adjunct to surgery and radiation and recurrent glioblastoma as an adjunct to surgery

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.