TheraRadar

Pharma Intelligence, Simplified

Data updated: Mar 10, 2026

BEYFORTUS

NIRSEVIMAB-ALIP Fusion Protein Inhibitors
Respiratory Approved 2023-07-17

BEYFORTUS is a monoclonal antibody indicated for the prevention of Respiratory Syncytial Virus (RSV) lower respiratory tract disease. It is administered to neonates and infants who are born during or entering their first RSV season. Additionally, the treatment is approved for children up to 24 months of age who remain vulnerable to severe RSV disease through their second RSV season. This therapeutic serves as a preventative measure for pediatric populations at risk of RSV-related complications.

Source: FDA Label • AstraZeneca • Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody

How BEYFORTUS Works

BEYFORTUS functions as a respiratory syncytial virus (RSV) F protein-directed fusion inhibitor. As a monoclonal antibody, it targets the F protein on the surface of the virus to exhibit anti-RSV activity. By binding to this protein, the drug inhibits the virus's ability to fuse with and enter host cells. This mechanism prevents the virus from establishing an infection that leads to lower respiratory tract disease.

Source: FDA Label
3
Indications
--
Phase 3 Trials
2
Years on Market

Details

Status
Prescription
First Approved
2023-07-17
Routes
INJECTION
Dosage Forms
INJECTABLE

Companies

Active Ingredient: NIRSEVIMAB-ALIP

BEYFORTUS Approval History

Loading approval history...

What BEYFORTUS Treats

1 indications

BEYFORTUS is approved for 1 conditions since its original approval in 2023. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Respiratory Syncytial Virus Lower Respiratory Tract Disease
Source: FDA Label

Drugs Similar to BEYFORTUS

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

Full development history with FDA approval milestones

Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

BEYFORTUS FDA Label Details

Pro

Indications & Usage

FDA Label (PDF)

BEYFORTUS is indicated for the prevention of Respiratory Syncytial Virus (RSV) lower respiratory tract disease in: Neonates and infants born during or entering their first RSV season. Children up to 24 months of age who remain vulnerable to severe RSV disease through their second RSV season. BEYFORTUS is a respiratory syncytial virus (RSV) F protein-directed fusion inhibitor indicated for the prevention of RSV lower respiratory tract disease in: Neonates and infants born during or entering their first RSV season. Children up to 24 months of age who remain vulnerable to severe RSV disease throu...

Want competitive intelligence?

See who's developing similar drugs and track their progress

View Pipeline Dashboard

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.