TheraRadar

Pharma Intelligence, Simplified

Landscape Oncology

Squamous Cell Carcinoma

495 clinical trials

296 active
/
495 total (since 2015)
87
Phase 1 Active
175 total
224
Phase 2 Active
351 total
33
Phase 3 Active
48 total
1
Phase 4 Active
2 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Regeneron 2 5 2
Merck 2 1 0
Alentis Therapeutics AG 2 0 0
Replimune Inc. 2 0 0
Ankyra Therapeutics, Inc 2 0 0
Incyte Corporation 1 3 1
AstraZeneca 1 1 0
PDS Biotechnology Corp. 1 1 0
Rakuten Medical, Inc. 1 0 1
Privo Technologies 1 1 0
Neonc Technologies, Inc. 1 0 0
Terremoto Biosciences Inc. 1 0 0
VSPharmTech Co.,Ltd. 1 0 0
ALX Oncology Inc. 1 0 0
Normunity AccelCo, Inc. 1 0 0
NCT05063552 ACTIVE NOT RECRUITING
Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers
National Cancer Institute (NCI) n=430
NCT03952585 ACTIVE NOT RECRUITING
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer
National Cancer Institute (NCI) n=384
NCT04444921 ACTIVE NOT RECRUITING
EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients
National Cancer Institute (NCI) n=205
NCT03233711 ACTIVE NOT RECRUITING
Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer
National Cancer Institute (NCI) n=344
NCT07061977 RECRUITING
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
National Cancer Institute (NCI) n=336
NCT06568172 RECRUITING
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
National Cancer Institute (NCI) n=420
NCT06992427 RECRUITING
High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer
Alliance for Clinical Trials in Oncology n=228
NCT07445048 NOT YET RECRUITING
Postoperative Radiotherapy Combined With Nimotuzumab Followed by Bemcentinib in High-Risk Patients With Head and Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University n=370
NCT02466971 ACTIVE NOT RECRUITING
Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers
National Cancer Institute (NCI) n=450
NCT05721755 RECRUITING
Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck
ECOG-ACRIN Cancer Research Group n=290
NCT06585410 RECRUITING
Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals n=369
NCT06589804 RECRUITING
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
National Cancer Institute (NCI) n=158
NCT06563479 RECRUITING
A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer
Memorial Sloan Kettering Cancer Center n=291
NCT07371611 RECRUITING
Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma
Qunxing Li,MD n=104
NCT04255849 ACTIVE NOT RECRUITING
Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV
Weill Medical College of Cornell University n=700
NCT04333537 RECRUITING
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
NRG Oncology n=686
NCT03801876 RECRUITING
Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer
NRG Oncology n=300
NCT07333274 RECRUITING
Compare Radiotherapy Plus Nimotuzumab Versus Radiotherapy Alone in Platinum-ineligible Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma
Shandong Cancer Hospital and Institute n=335
NCT06115499 ACTIVE NOT RECRUITING
The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer
Alliance for Clinical Trials in Oncology n=10
NCT07311057 ENROLLING BY INVITATION
Investigation of Effect of Formulated Methylene Blue on Treatment of Squamous Cell Carcinoma Skin Cancer in Inoperable Patients and Not Suitable for Radiotherapy
Daryoush Hamidi Alamdari, PhD n=20
NCT06790966 ACTIVE NOT RECRUITING
Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
PDS Biotechnology Corp. n=351
NCT07264075 NOT YET RECRUITING
Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN
Groupe Oncologie Radiotherapie Tete et Cou n=780
NCT05381597 RECRUITING
5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
Boston University n=200
NCT05333523 RECRUITING
Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.
Radboud University Medical Center n=242
NCT03969004 ACTIVE NOT RECRUITING
Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals n=415
NCT05943795 ACTIVE NOT RECRUITING
A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd. n=589
NCT05893888 RECRUITING
Safety and Efficacy Study of PRV111 and PRV211 in Subjects With Oral Squamous Cell Carcinoma
Privo Technologies n=40
NCT02305654 RECRUITING
International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)
Institute of Cancer Research, United Kingdom n=200
NCT06258811 RECRUITING
Neoadjuvant Immunochemotherapy for LAOSCC
Lai-ping Zhong n=134
NCT06030440 RECRUITING
De-Intensification of Postoperative Radiotherapy in Patients with Squamous Cell Carcinoma of the Head and Neck
University of Erlangen-Nürnberg Medical School n=508
NCT06692556 NOT YET RECRUITING
Study of a Strategy Integrating Adjuvant Radiation Therapy Versus Strategy Based on Monitoring in the Treatment of Carcinomas Spinocellular With High Risk of Recurrence
Centre Leon Berard n=266
NCT05798793 RECRUITING
Neoadjuvant Anti-PD-1 Immunotherapy With Chemotherapy in Resectable Locally Advanced Oral Squamous Cell Carcinoma
Hospital of Stomatology, Wuhan University n=309
NCT05125055 RECRUITING
Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC
Shanghai Jiao Tong University School of Medicine n=80
NCT05050162 SUSPENDED
Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer
NRG Oncology n=1,714
NCT03258554 COMPLETED
Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin
National Cancer Institute (NCI) n=196
NCT04472429 COMPLETED
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).
Incyte Corporation n=308
NCT04458909 TERMINATED
Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer
National Cancer Institute (NCI) n=15
NCT06513884 WITHDRAWN
A Study of HB-202/HB-201 With Pembrolizumab in Patients With HPV16+ Recurrent/Metastatic Oropharyngeal Cancer
Hookipa Biotech GmbH
NCT03257267 COMPLETED
Study of Cemiplimab in Adults With Cervical Cancer
Regeneron Pharmaceuticals n=608
NCT03115476 TERMINATED
A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or Scalp
LEO Pharma n=563
NCT06781073 COMPLETED
Nimotuzumab in Combined With Chemotherapy for Treatment of IVB Stage,Rrecurrent or Persistent Cervical Carcinoma
Biotech Pharmaceutical Co., Ltd. n=118
NCT02923258 COMPLETED
Postoperative CCRT With Docetaxel vs Cisplatin in High Risk Oral Cavity Cancer
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University n=224
NCT02997553 COMPLETED
Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery
Institut de Cancérologie de Lorraine n=744
NCT03237325 COMPLETED
DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer
Soligenix n=266
NCT04196075 COMPLETED
The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer
Chinese University of Hong Kong n=30
NCT02236936 TERMINATED
Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the Head and Neck
Arbeitsgemeinschaft medikamentoese Tumortherapie n=8
NCT04137627 COMPLETED
Melatonin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response in Locally Advanced Oral Squamous Cell Carcinoma
Indonesia University n=50
NCT02765919 COMPLETED
A Randomised Controlled Trial Between Two Different HDR Brachytherapy Schedule in Locally Advanced Carcinoma of Uterine Cervix
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh n=30