TheraRadar

Pharma Intelligence, Simplified

Landscape Oncology

SCLC

543 clinical trials

306 active
/
543 total (since 2015)
126
Phase 1 Active
248 total
192
Phase 2 Active
326 total
52
Phase 3 Active
74 total
3
Phase 4 Active
6 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Amgen 10 1 1
AstraZeneca 9 9 1
Merck 6 2 0
Boehringer Ingelheim 6 0 0
Shanghai Henlius Biotech 5 1 0
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 5 0 0
Bristol-Myers Squibb 4 4 0
Pfizer 4 0 0
AbbVie 3 5 4
Novartis 3 3 2
Daiichi Sankyo 3 0 0
MediLink Therapeutics (Suzhou) Co., Ltd. 3 0 0
Sichuan Baili Pharmaceutical Co., Ltd. 3 0 0
Biotheus Inc. 3 0 0
BeiGene 2 3 0
NCT06646276 RECRUITING
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Bristol-Myers Squibb n=530
NCT06992609 RECRUITING
Durvalumab After Chemoradiotherapy in Limited Stage Small Cell Lung Cancer.
AstraZeneca n=70
NCT06203210 RECRUITING
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Daiichi Sankyo n=540
NCT06117774 RECRUITING
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
Amgen n=400
NCT06801834 RECRUITING
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Gilead Sciences n=695
NCT04665856 ACTIVE NOT RECRUITING
Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer
Hoffmann-La Roche n=123
NCT02542293 ACTIVE NOT RECRUITING
Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)
AstraZeneca n=953
NCT06881784 RECRUITING
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Revolution Medicines, Inc. n=420
NCT05153239 ACTIVE NOT RECRUITING
Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)
PharmaMar n=705
NCT02438722 ACTIVE NOT RECRUITING
S1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer
SWOG Cancer Research Network n=174
NCT07365241 NOT YET RECRUITING
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
AbbVie n=531
NCT07362459 RECRUITING
A Study to Evaluate the Safety and Tolerability of SCTB14 as First-Line Therapy in Non-Small Cell Lung Cancer.
Sinocelltech Ltd. n=246
NCT05353257 ACTIVE NOT RECRUITING
A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer
Shanghai Henlius Biotech n=511
NCT07226999 RECRUITING
A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
Pfizer n=550
NCT05740566 ACTIVE NOT RECRUITING
Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer
Amgen n=509
NCT02511106 ACTIVE NOT RECRUITING
AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy.
AstraZeneca n=682
NCT03003962 ACTIVE NOT RECRUITING
Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL)
AstraZeneca n=669
NCT02201992 ACTIVE NOT RECRUITING
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
ECOG-ACRIN Cancer Research Group n=166
NCT07144280 RECRUITING
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Pfizer n=680
NCT03703297 ACTIVE NOT RECRUITING
Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapy
AstraZeneca n=730
NCT03043872 ACTIVE NOT RECRUITING
Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)
AstraZeneca n=987
NCT05468489 ACTIVE NOT RECRUITING
To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC
Shanghai Henlius Biotech n=200
NCT07145333 ACTIVE NOT RECRUITING
Pharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair n=600
NCT07106528 NOT YET RECRUITING
Organoid-guided vs Topotecan Therapy in Relapsed Extensive-Stage Small Cell Lung Cancer
Peking Union Medical College Hospital n=128
NCT01064466 ACTIVE NOT RECRUITING
Pharmacogenomics ANDA SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair n=600
NCT05224141 ACTIVE NOT RECRUITING
Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)
Merck Sharp & Dohme LLC n=460
NCT07050043 RECRUITING
Low Dose Nivolumab With Chemotherapy vs Standard Chemotherapy as First-Line Treatment in Advanced or Metastatic NSCLC
Dr Arvindran A/L Alaga n=123
NCT04624204 ACTIVE NOT RECRUITING
Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)
Merck Sharp & Dohme LLC n=672
NCT06954246 RECRUITING
A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Qilu Pharmaceutical Co., Ltd. n=450
NCT07015892 NOT YET RECRUITING
Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial
Instituto de Investigación Biomédica de Salamanca n=300
NCT07010263 NOT YET RECRUITING
A Study of AK112 as Consolidation Treatment for Patients With Limited Stage Small-cell Lung Cancer Who Have Not Progressed Following Concurrent Chemoradiation Therapy
Akeso n=480
NCT07008716 RECRUITING
Omitting CTV for Primary Tumor in LS-SCLC
Sun Yat-sen University n=852
NCT06961201 NOT YET RECRUITING
Nano-crystalline Megestrol Acetate Combined With Standard Treatment Versus Standard Treatment for First-line Extensive-stage Small Cell Lung Cancer in the Cachexia Phase
Changchun GeneScience Pharmaceutical Co., Ltd. n=94
NCT06500026 RECRUITING
A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd. n=714
NCT04853342 RECRUITING
To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy
Allist Pharmaceuticals, Inc. n=318
NCT06872541 ACTIVE NOT RECRUITING
Evaluation of Platelet Aggregability in Patients with Non-small Cell Lung Carcinomas
University of Sao Paulo n=100
NCT06840704 RECRUITING
Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer
Hunan Cancer Hospital n=121
NCT06612151 RECRUITING
A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer
MediLink Therapeutics (Suzhou) Co., Ltd. n=438
NCT06616532 RECRUITING
PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer
Biotheus Inc. n=404
NCT06496048 RECRUITING
Lurbinectedin or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed SCLC
Luye Pharma Group Ltd. n=180
NCT06719336 NOT YET RECRUITING
Addition of Thoracic Consolidation Radiotherapy to the Maintenance Immunotherapy for ES-SCLC (STONE-001)
Anhui Shi, MD n=182
NCT06498479 RECRUITING
ARTEMIS-008:HS-20093 Compared With Topotecan in Subjects With Relapsed Small Cell Lung Cancer
Hansoh BioMedical R&D Company n=460
NCT06581380 NOT YET RECRUITING
JK-1201I Compared with Topotecan in Patients with Relapsed Extensive Stage Small Cell Lung Cancer
JenKem Technology Co., Ltd. n=394
NCT06469879 NOT YET RECRUITING
A Clinical Study of TQB2450 Combined With Anlotinib in Limited-Stage Small Cell Lung Cancer Patients
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. n=358
NCT06095583 RECRUITING
Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)
Shanghai Junshi Bioscience Co., Ltd. n=756
NCT06441344 NOT YET RECRUITING
Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell
Taizhou Hospital n=136
NCT06128837 RECRUITING
Study of LY01610 in Patients With Recurrent Small Cell Lung Cancer
Luye Pharma Group Ltd. n=686
NCT06247605 RECRUITING
A Phase IIII Study of AL8326 in Small Cell Lung Cancer
Advenchen Laboratories Nanjing Ltd. n=243
NCT05623267 RECRUITING
Sugemalimab as Consolidation Therapy in Patients With LS-SCLC Following cCRT or sCRT
Sun Yat-sen University n=346
NCT05496166 NOT YET RECRUITING
The Efficiency of Surgery and Radiotherapy After SHR-1316 (Adebrelimab) and Platinum-containing Doublet Induction Therapy for Limited-stage Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China n=348
NCT04762459 ENROLLING BY INVITATION
Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection
Chinese Academy of Medical Sciences n=606
NCT04829708 RECRUITING
Efficacy and Safety of Prophylactic Cranial Irradiation Versus MRI Surveillance in Patients With Limited-stage Small Cell Lung Cancer Who Achieved Remission After First-line Chemoradiotherapy
Shandong Cancer Hospital and Institute n=534
NCT02635009 COMPLETED
Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Cell Lung Cancer
NRG Oncology n=418
NCT03088540 COMPLETED
Study of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)
Regeneron Pharmaceuticals n=712
NCT04256421 COMPLETED
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Hoffmann-La Roche n=490
NCT04063163 COMPLETED
A Phase III Study to Investigate Efficacy and Safety of HLX10 + Chemotherapy in Patients With ES-SCLC
Shanghai Henlius Biotech n=585
NCT04774380 COMPLETED
Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer
AstraZeneca n=152
NCT04005716 COMPLETED
Study of Platinum Plus Etoposide With or Without Tislelizumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer
BeiGene n=457
NCT03088813 COMPLETED
Study of Irinotecan Liposome Injection (ONIVYDE®) in Patients With Small Cell Lung Cancer
Ipsen n=491
NCT02349412 COMPLETED
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
Alliance for Clinical Trials in Oncology n=405
NCT04012606 COMPLETED
Toripalimab in Combination With Platinum Plus Etoposidein Patients With Extensive-Stage Small Cell Lung Cancer
Shanghai Junshi Bioscience Co., Ltd. n=442
NCT04712903 COMPLETED
Durvalumab Plus Chemotherapy in Untreated Patients With Extensive-Stage Small Cell Lung Cancer
AstraZeneca n=101
NCT04830813 COMPLETED
Phase 3 Clinical Study of Chiauranib Capsule in Patients With Small-cell Lung Cancer
Chipscreen Biosciences, Ltd. n=184
NCT04449861 COMPLETED
Durvalumab Plus Chemotherapy in ES-SCLC (Oriental)
AstraZeneca n=166
NCT02973789 COMPLETED
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)
NovoCure GmbH n=276
NCT02352948 COMPLETED
A Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer
AstraZeneca n=597
NCT04028050 COMPLETED
A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Hoffmann-La Roche n=155
NCT02763579 COMPLETED
A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
Hoffmann-La Roche n=503
NCT03066778 COMPLETED
A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)
Merck Sharp & Dohme LLC n=453
NCT03033511 TERMINATED
A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)
AbbVie n=748
NCT03061812 COMPLETED
Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)
AbbVie n=444
NCT03516084 TERMINATED
A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer
Zai Lab (Shanghai) Co., Ltd. n=185
NCT03098030 COMPLETED
Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer
United Therapeutics n=483
NCT03334487 WITHDRAWN
Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer
AbbVie