Landscape → Immunology

Lupus

854 clinical trials

415 active

854 total (since 2015)

179

Phase 1 Active

297 total

174

Phase 2 Active

381 total

Phase 3 Active

154 total

Phase 4 Active

138 total

Top Sponsors (Industry)

Sorted by active Active Done Failed

Novartis 10 2 4

AstraZeneca 9 7 2

Bristol-Myers Squibb 6 10 1

China Immunotech (Beijing) Biotechnology Co., Ltd. 6 0 0

GSK 5 7 1

Roche 5 3 1

Biogen 5 2 0

Chongqing Precision Biotech Co., Ltd 5 0 0

Eli Lilly 4 4 3

Viatris Innovation GmbH 4 2 0

Amgen 3 6 4

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 3 1 0

Vanda Pharmaceuticals 3 1 0

Beijing Mabworks Biotech Co., Ltd. 3 0 0

Miltenyi Biomedicine GmbH 3 0 0

NCT06475742 ENROLLING BY INVITATION

Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus

Viatris Innovation GmbH n=680

NCT06044337 ENROLLING BY INVITATION

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Biogen n=322

NCT05672576 ACTIVE NOT RECRUITING

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus

Viatris Innovation GmbH n=451

NCT05648500 RECRUITING

A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus

Viatris Innovation GmbH n=420

NCT05531565 RECRUITING

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Biogen n=450

NCT07226765 RECRUITING

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Amgen n=250

NCT07369011 RECRUITING

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

Eli Lilly and Company n=800

NCT07438496 NOT YET RECRUITING

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

Janssen Research & Development, LLC n=600

NCT07225686 RECRUITING

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

Amgen n=250

NCT05835310 RECRUITING

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

AstraZeneca n=100

NCT07434050 NOT YET RECRUITING

A Study of XW003 in Obese Participants With Obstructive Sleep Apnea Receiving Positive Airway Pressure Therapy

Hangzhou Sciwind Biosciences Co., Ltd. n=140

NCT05799378 RECRUITING

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

NYU Langone Health n=330

NCT05352919 ENROLLING BY INVITATION

An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Biogen n=864

NCT05138133 ACTIVE NOT RECRUITING

Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

AstraZeneca n=359

NCT07430306 NOT YET RECRUITING

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

AstraZeneca n=245

NCT06617325 RECRUITING

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

UCB Biopharma SRL n=450

NCT05624749 ACTIVE NOT RECRUITING

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

Novartis Pharmaceuticals n=288

NCT07201129 RECRUITING

A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment

Viatris Innovation GmbH n=300

NCT07418554 NOT YET RECRUITING

Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin

University Hospital, Strasbourg, France n=120

NCT04877691 ACTIVE NOT RECRUITING

Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus

AstraZeneca n=367

NCT07336277 NOT YET RECRUITING

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

Emory University n=30

NCT07405970 NOT YET RECRUITING

A Phase 3 Clinical Study of MIL62 in Systemic Lupus Erythematosus

Beijing Mabworks Biotech Co., Ltd. n=316

NCT07406360 NOT YET RECRUITING

A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age

GlaxoSmithKline n=1,209

NCT06015737 RECRUITING

A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

AstraZeneca n=302

NCT04895241 ACTIVE NOT RECRUITING

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Biogen n=548

NCT04976322 ENROLLING BY INVITATION

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

UCB Biopharma SRL n=760

NCT04221477 ACTIVE NOT RECRUITING

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis

Hoffmann-La Roche n=271

NCT07387094 NOT YET RECRUITING

A Study of XW003 in Obese Participants With Obstructive Sleep Apnea But Not Receive Positive Airway Pressure Therapy

Hangzhou Sciwind Biosciences Co., Ltd. n=140

NCT05639114 ACTIVE NOT RECRUITING

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

Novartis Pharmaceuticals n=436

NCT05843643 RECRUITING

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

AbbVie n=1,000

NCT04961567 ACTIVE NOT RECRUITING

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Biogen n=562

NCT07355218 NOT YET RECRUITING

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany n=202

NCT06133972 RECRUITING

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

Novartis Pharmaceuticals n=550

NCT07332481 NOT YET RECRUITING

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany n=202

NCT07332442 NOT YET RECRUITING

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea

Yale University n=250

NCT06711887 RECRUITING

Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)

Novartis Pharmaceuticals n=315

NCT04963296 ACTIVE NOT RECRUITING

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

Hoffmann-La Roche n=303

NCT05126277 RECRUITING

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

Novartis Pharmaceuticals n=462

NCT05617677 ACTIVE NOT RECRUITING

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Bristol-Myers Squibb n=516

NCT04652882 RECRUITING

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

Vanda Pharmaceuticals n=70

NCT05620407 ACTIVE NOT RECRUITING

A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus

Bristol-Myers Squibb n=513

NCT06568367 RECRUITING

Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

Axsome Therapeutics, Inc. n=520

NCT04702256 RECRUITING

Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF

Assistance Publique - Hôpitaux de Paris n=196

NCT05474846 RECRUITING

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

M.D. Anderson Cancer Center n=188

NCT05625360 RECRUITING

REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss

Wake Forest University Health Sciences n=160

NCT04582136 ACTIVE NOT RECRUITING

Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus

Chinese SLE Treatment And Research Group n=146

NCT04801771 ACTIVE NOT RECRUITING

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

Inspire Medical Systems, Inc. n=57

NCT04877093 RECRUITING

Repurposing Low-Dose Clonidine for PTSD in Veterans

Wake Forest University Health Sciences n=32

NCT05433350 ACTIVE NOT RECRUITING

Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients

Drugs for Neglected Diseases n=35

NCT07047092 NOT YET RECRUITING

Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure

Assistance Publique - Hôpitaux de Paris n=386

NCT06931028 RECRUITING

A Study of IBI362 in Chinese Subjects With Obstructive Sleep Apnea and BMI≥28 kg/m2

Innovent Biologics (Suzhou) Co. Ltd. n=260

NCT05638087 ACTIVE NOT RECRUITING

Dexamethasone Treatment for OSA in Children

The Hospital for Sick Children n=10

NCT06970626 RECRUITING

Quality of Recovery in Laparoscopic Sleeve Gastrectomy Using Dexmedetomidine Infusion Versus Laparoscopic TAP Block in Combination With Paragastric Neural Block

Alexandria University n=60

NCT06965244 NOT YET RECRUITING

Lenalidomide vs Methotrexate in Difficult-to-treat Cutaneous Lupus Erythematosus

Assistance Publique - Hôpitaux de Paris n=122

NCT06146101 ACTIVE NOT RECRUITING

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA

Incannex Healthcare Ltd n=560

NCT05929079 ACTIVE NOT RECRUITING

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

Eli Lilly and Company n=1,000

NCT05929066 ACTIVE NOT RECRUITING

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight

Eli Lilly and Company n=2,300

NCT06904729 RECRUITING

Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children

Guangzhou Women and Children's Medical Center n=50

NCT06262594 RECRUITING

Lemborexant Treatment of Insomnia Linked to Epilepsy

University of Manitoba n=26

NCT06815835 NOT YET RECRUITING

Non-interference Study of MR and Yellow Fever Vaccines Among Bangladeshi Infants Aged 9-12 Months

International Centre for Diarrhoeal Disease Research, Bangladesh n=1,530

NCT05458622 ACTIVE NOT RECRUITING

3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erithematosus Study Protocol

University Hospital, Brest n=25

NCT06701396 RECRUITING

Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD) and the CRY1Δ11 Variant

Vanda Pharmaceuticals n=60

NCT06681974 RECRUITING

OROPHARYNGEAL MYOFUNCTIONAL THERAPY IN OBSTRUCTIVE SLEEP APNEA

Instituto de Investigación Marqués de Valdecilla n=30

NCT03747159 ACTIVE NOT RECRUITING

Synergetic B-cell Immunomodulation in SLE - 2nd Study.

Leiden University Medical Center n=70

NCT06618573 RECRUITING

Safety of Administering Isoniazid to SLE Patients to Prevent TB

Universitas Padjadjaran n=60

NCT06496282 RECRUITING

Lemborexant on Improving Sleep Quality Among Hospital Rotating Shift Workers

Phramongkutklao College of Medicine and Hospital n=50

NCT06406205 RECRUITING

A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis

Qilu Pharmaceutical Co., Ltd. n=270

NCT05657925 NOT YET RECRUITING

Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9)

University of Calgary n=24

NCT05930184 RECRUITING

Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy

Khon Kaen University n=98

NCT06281561 NOT YET RECRUITING

Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance

The First Affiliated Hospital of Xiamen University n=110

NCT05339217 RECRUITING

Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus Erythematosus

Liu Tian n=60

NCT05361707 RECRUITING

Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances

Vanda Pharmaceuticals n=100

NCT05911971 NOT YET RECRUITING

Upper Airway Reeducation in Moderate Obstructive Sleep Apnea Syndrome

Assistance Publique - Hôpitaux de Paris n=54

NCT06795776 COMPLETED

Eschscholzia Study

A. Vogel AG n=104

NCT05001737 COMPLETED

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Swedish Orphan Biovitrum n=33

NCT05288855 TERMINATED

Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis

Aurinia Pharmaceuticals Inc. n=9

NCT05962788 TERMINATED

Long-Term Voclosporin Treatment in Adolescent and Pediatric Subjects With Lupus Nephritis

Aurinia Pharmaceuticals Inc. n=4

NCT05306574 TERMINATED

A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)

Vor Biopharma n=91

NCT06456567 WITHDRAWN

A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2)

Vor Biopharma

NCT06399003 COMPLETED

Comparison Study of SIBP's MMR Vaccine Versus GSK MMR Vaccine in Children Aged 9-11 Months

Shanghai Institute Of Biological Products n=1,200

NCT05458128 COMPLETED

A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia

Harmony Biosciences Management, Inc. n=119

NCT05113745 COMPLETED

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

Axsome Therapeutics, Inc. n=68

NCT04931563 COMPLETED

Anifrolumab Asian PhIII Efficacy Study for Systemic Lupus Erythematosus (SLE)

AstraZeneca n=277

NCT04451668 COMPLETED

An Open Label Study of FT218 in Subjects With Narcolepsy

Avadel n=184

NCT02630628 COMPLETED

Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis

The University of Hong Kong n=130

NCT03087955 COMPLETED

Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense

Drugs for Neglected Diseases n=208

NCT03227263 COMPLETED

BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT).

Hospices Civils de Lyon n=24

NCT05609812 WITHDRAWN

Atacicept in Subjects With Active Lupus Nephritis (COMPASS)

Vera Therapeutics, Inc.

NCT04181762 TERMINATED

Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis

Novartis Pharmaceuticals n=275

NCT05232864 TERMINATED

Open-label Extension Study of Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Lupus Nephritis

Novartis Pharmaceuticals n=31

NCT04294667 COMPLETED

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

UCB Biopharma SRL n=321

NCT05412004 COMPLETED

Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea

Eli Lilly and Company n=469

NCT03517722 TERMINATED

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

Janssen Research & Development, LLC n=516

NCT05516953 COMPLETED

Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery

Tanta University n=100

NCT05620641 COMPLETED

Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

Tanta University n=100

NCT05256017 COMPLETED

Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects

Drugs for Neglected Diseases n=1,208

NCT05059223 COMPLETED

A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy

Axsome Therapeutics, Inc. n=90

NCT06103825 COMPLETED

A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients with Obstructive Sleep Apnea (OSA)

Ignis Therapeutics (Suzhou) Limited n=204

NCT03312907 COMPLETED

A Study to Evaluate the Efficacy and Safety of Belimumab Administered in Combination With Rituximab to Adult Subjects With Systemic Lupus Erythematosus (SLE) - BLISS-BELIEVE

GlaxoSmithKline n=292

NCT04060888 WITHDRAWN

A Study of Ustekinumab in Chinese Participants With Active Systemic Lupus Erythematosus

Janssen Research & Development, LLC

NCT03974178 COMPLETED

Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense

Drugs for Neglected Diseases n=45

NCT03025789 COMPLETED

Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage

Drugs for Neglected Diseases n=174

NCT04152655 WITHDRAWN

A Study of Efficacy and Safety of Idebenone Vs. Placebo in Prodromal Parkinson Disease

Second Affiliated Hospital, School of Medicine, Zhejiang University

NCT05611372 WITHDRAWN

Efficacy and Safety of Rasagiline in Prodromal Parkinson's Disease

Second Affiliated Hospital, School of Medicine, Zhejiang University

NCT04549168 COMPLETED

A Study of Lemborexant in Chinese Participants With Insomnia Disorder

Eisai Co., Ltd. n=194

NCT05456360 TERMINATED

Implementation of Digital Vital Sign Monitoring to Decrease Sleep Interruption and Enhance Recovery in Phase II of the PROmoting Sleep, Patient Engagement and Recovery (PROSPER) Project

M.D. Anderson Cancer Center n=89

NCT05749939 COMPLETED

Acceptance Commitment Therapy for Caregivers of People with Memory Loss

Utah State University n=121

NCT06690723 COMPLETED

Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea

University Malaysia Sarawak n=160

NCT02457221 COMPLETED

A Study to Compare the Efficacy and Safety of Tacrolimus Capsules and Cyclophosphamide Injection in Treatment of Lupus Nephritis

Astellas Pharma China, Inc. n=314

NCT06390722 WITHDRAWN

A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis

AbbVie

NCT03412591 COMPLETED

The Efficacy of Suvorexant in Treatment of Patients With Substance Use Disorder and Insomnia: A Pilot Open Trial

Milton S. Hershey Medical Center n=28

NCT04603781 SUSPENDED

CBD Oil for Reducing Emotional Impact of COVID-19

University of Texas at Austin n=200

NCT05232266 COMPLETED

The Effectiveness of a Caralluma Fimbriata Extract on Stress, Sleep and Neurotransmitters

RDC Clinical Pty Ltd n=129

NCT05825209 COMPLETED

Effectiveness of Food-grown Magnesium on Sleep Quality/Quantity

RDC Clinical Pty Ltd n=84

NCT03745898 TERMINATED

The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea

Brigham and Women's Hospital n=98

NCT05223166 COMPLETED

A Clinical Study to Evaluate the Efficacy and Safety of Pitolisant in the Treatment of EDS in Patients With OSA

Citrine Medicine Limited n=240

NCT03843125 TERMINATED

A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE)

Eli Lilly and Company n=1,147

NCT04082416 COMPLETED

Study of Recombinant Human B Lymphocyte(RC18) Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus(SLE)

RemeGen Co., Ltd. n=335

NCT03021499 COMPLETED

Aurinia Renal Response in Active Lupus With Voclosporin

Aurinia Pharmaceuticals Inc. n=358

NCT02856594 COMPLETED

Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep

Massachusetts General Hospital n=469

NCT04806113 COMPLETED

COVID-19 Vaccine in Immunosuppressed Adults With Autoimmune Diseases

McGill University Health Centre/Research Institute of the McGill University Health Centre n=220

NCT05194618 COMPLETED

Efficacy and Safety of Valerian Root Extract and Lavender Essential Oil Combination, Over 4 Weeks in Subjects With Sleep Complaints

University Hospital, Bordeaux n=114

NCT03616912 TERMINATED

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus

Eli Lilly and Company n=830

NCT02794285 COMPLETED

Long Term Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus

AstraZeneca n=559

NCT02446912 COMPLETED

Efficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

AstraZeneca n=460

NCT02446899 COMPLETED

Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

AstraZeneca n=373

NCT03597464 COMPLETED

Aurinia Renal Assessments 2: Aurinia Renal Response in Lupus With Voclosporin

Aurinia Pharmaceuticals Inc. n=216

NCT03715465 COMPLETED

The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder

University of Michigan n=44

NCT03616964 COMPLETED

A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE-BRAVE II)

Eli Lilly and Company n=778

NCT04113187 COMPLETED

Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients

University Hospital, Bordeaux n=15

NCT05326841 COMPLETED

Effect of Cholecalciferol Supplementation on Disease Activity and Quality of Life of Systemic Lupus Erythematosus Patients .

Dr Cipto Mangunkusumo General Hospital n=60

NCT02720744 COMPLETED

Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

Avadel n=212

NCT04084990 TERMINATED

Sleep Apnea and Fetal Growth Restriction

Washington University School of Medicine n=3

NCT02987985 COMPLETED

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

University of Saskatchewan n=50

NCT04394143 COMPLETED

Effect of AD128 to Treat Obstructive Sleep Apnea

Raphael Heinzer n=15

NCT03545997 TERMINATED

Montelukast for Patients With Obstructive Sleep Apnea Syndrome

University Hospital, Grenoble n=1

NCT03075241 COMPLETED

Z-Drugs for Sleep Disorders in Alzheimer's Disease

Brasilia University Hospital n=62

NCT03148990 COMPLETED

Study to Evaluate the Immunogenicity, Reatogenicity and Safety of Double Viral Vaccine (MR) for Measles and Rubella

The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) n=432

NCT02739568 COMPLETED

Pitolisant (BF2.649) in the Treatment of EDS in Patients With OSA

Bioprojet n=389

NCT03109418 TERMINATED

Intraoperative Low-dose Ketamine Infusion for Patients With Obstructive Sleep Apnea

University of Alabama at Birmingham n=9

NCT04183114 COMPLETED

Immunogenicity & Safety of Bio Farma's Measles-Rubella (MR) Vaccine in Indonesian Infants (Bridging Study)

PT Bio Farma n=540

NCT02750306 COMPLETED

Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061)

Merck Sharp & Dohme LLC n=285

NCT02732912 COMPLETED

SleepSure: A Trial to Assess the Effects of Eye Masks and Earplugs on Hospital Inpatient Sleep

Oxford University Hospitals NHS Trust n=206

NCT02348619 COMPLETED

"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

Jazz Pharmaceuticals n=174

NCT02348606 COMPLETED

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

Jazz Pharmaceuticals n=476

NCT02348632 COMPLETED

"A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA"

Jazz Pharmaceuticals n=645

NCT02504645 COMPLETED

A 52-Week, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a 200-mcg Dose of IPP-201101 Plus Standard of Care in Patients With Systemic Lupus Erythematosus

ImmuPharma n=202

NCT03427151 COMPLETED

Study of Repeated Administration of a 200-mcg Dose of IPP-201101 Plus Standard of Care in Patients With Systemic Lupus Erythematosus

ImmuPharma n=62

NCT03127800 TERMINATED

Morphine in Moderate Obstructive Sleep Apnoea

Papworth Hospital NHS Foundation Trust n=6

NCT01773616 TERMINATED

Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis

Imperial College London n=24

NCT02514967 TERMINATED

CHABLIS7.5: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus With or Without Nephritis

Anthera Pharmaceuticals n=3

NCT01991899 COMPLETED

Study of Immunogenicity, Reactogenicity and Safety of the Combined Measles, Mumps and Rubella Vaccine Produced by Bio-Manguinhos/Fiocruz in Children 12-15 Months of Age, Followed by Tetraviral Vaccine in Children 15-18 Months.

The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) n=1,560

NCT02074020 WITHDRAWN

CHABLIS-SC2: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus With or Without Nephritis

Anthera Pharmaceuticals

NCT01733043 WITHDRAWN

Sedative Effects in Obstructive Sleep Apnea

Duke University

NCT07447986 NOT YET RECRUITING

To Evaluate the Efficacy and Safety of SG301 SC Injection in Systemic Lupus Erythematosus

Hangzhou Sumgen Biotech Co., Ltd.

NCT06897930 RECRUITING

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

AstraZeneca

NCT05350215 RECRUITING

Atomoxetine and DAW2022 on OSA Severity

Brigham and Women's Hospital

NCT06947473 RECRUITING

Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.

Beijing GoBroad Hospital

NCT07409181 NOT YET RECRUITING

A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

Boehringer Ingelheim

NCT06947460 RECRUITING

CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH

Beijing GoBroad Hospital

NCT05109364 ACTIVE NOT RECRUITING

Terazosin and Parkinson's Disease Extension Study

Cedars-Sinai Medical Center

NCT04386317 ACTIVE NOT RECRUITING

Terazosin Effect on Cardiac Changes in Early Parkinson's Disease

Cedars-Sinai Medical Center

NCT07443293 RECRUITING

IMPACT 360 for Parkinson's Disease

University of British Columbia

NCT06575426 RECRUITING

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Otsuka Pharmaceutical Factory, Inc.

NCT04218968 ACTIVE NOT RECRUITING

Cardiac Changes in Early Parkinson's Disease: A Follow up Study

Cedars-Sinai Medical Center

NCT03775096 ACTIVE NOT RECRUITING

Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)

Michele Tagliati, MD

NCT07440537 NOT YET RECRUITING

Evaluate the Efficacy and Safety of ICP-488 in Subjects With Cutaneous Lupus Erythematosus (CLE) Double-blind Study

Beijing InnoCare Pharma Tech Co., Ltd.

NCT07136077 RECRUITING

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

M.D. Anderson Cancer Center

NCT07015983 RECRUITING

A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

NCT06972303 RECRUITING

Mindfulness Meditation for Insomnia

Brigham and Women's Hospital

NCT06570798 RECRUITING

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

Amgen

NCT06839976 RECRUITING

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

Children's Hospital of Philadelphia

NCT07420205 NOT YET RECRUITING

Sleep Health in U.S. Marines

San Diego State University

NCT06121297 RECRUITING

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Cabaletta Bio

NCT06581198 RECRUITING

A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

Novartis Pharmaceuticals

NCT05798117 ACTIVE NOT RECRUITING

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

Novartis Pharmaceuticals

NCT06032923 RECRUITING

Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus

National Heart, Lung, and Blood Institute (NHLBI)

NCT06980805 RECRUITING

A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)

Immunovant Sciences GmbH

NCT05440422 RECRUITING

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT07301710 RECRUITING

Low-Tech Treatments for Obstructive Sleep Apnea

Uniformed Services University of the Health Sciences

NCT03527472 ACTIVE NOT RECRUITING

Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus

Vanderbilt University Medical Center

NCT07399782 NOT YET RECRUITING

Botulinum Toxin in the Palatopharyngeal Muscle for the Treatment of Obstructive Sleep Apnea

Hospital Felicio Rocho

NCT07393451 NOT YET RECRUITING

A Multicenter Phase 2a Clinical Study to Evaluate SIM0278 in Subjects With Active Lupus Nephritis

Simcere Pharmaceutical Co., Ltd

NCT05268289 RECRUITING

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Novartis Pharmaceuticals

NCT07010835 RECRUITING

Study of YK012 in Moderate to Severe Systemic Lupus Erythematosus

Excyte Biopharma Ltd

NCT05039619 RECRUITING

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Hoffmann-La Roche

NCT07266090 ENROLLING BY INVITATION

A Study to Evaluate the Safety,Tolerability,Pharmacokinetics and Pharmacodynamics of Cenerimod in Adult Chinese Participants With Moderate-to-severe Systemic Lupus Erythematosus (SLE)

Viatris Pharmaceuticals Co., Ltd.

NCT06935474 NOT YET RECRUITING

C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease

AbelZeta Inc.

NCT05303987 RECRUITING

Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea

Erin Kirkham

NCT05540327 ACTIVE NOT RECRUITING

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

NCT07364396 NOT YET RECRUITING

Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus

Curocell Inc.

NCT07363460 RECRUITING

Study to Assess Efficacy and Safety of HSK39297 Tablets in Patients With LN

Haisco Pharmaceutical Group Co., Ltd.

NCT06404112 ACTIVE NOT RECRUITING

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Duke University

NCT06557265 RECRUITING

A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)

Nkarta, Inc.

NCT07348055 RECRUITING

A Study of GR1803 in Systemic Lupus Erythematosus

Genrix (Shanghai) Biopharmaceutical Co., Ltd.

NCT07339488 ACTIVE NOT RECRUITING

Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma

Chuangzhen Chen

NCT07340463 RECRUITING

The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment

Nanjing University School of Medicine

NCT06717815 RECRUITING

Phase IIa Study for IPG11406 in Patients With Lupus Nephritis

Nanjing Immunophage Biotech Co., Ltd

NCT05039840 RECRUITING

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

Sanofi

NCT07260877 RECRUITING

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

Ventus Therapeutics U.S., Inc.

NCT07089121 RECRUITING

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

Cartesian Therapeutics

NCT07328581 NOT YET RECRUITING

BCMA-CD19 cCAR T for the Treatment of Refractory Lupus

iCell Gene Therapeutics

NCT07311200 NOT YET RECRUITING

A Study of D-2570 in Patients With Active Systemic Lupus Erythematosus (SLE)

InventisBio Co., Ltd

NCT07299422 NOT YET RECRUITING

A Study of SHR-2173 in Participants With Systemic Lupus Erythematosus

Guangdong Hengrui Pharmaceutical Co., Ltd

NCT05856448 ACTIVE NOT RECRUITING

A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus

Galapagos NV

NCT05796206 ACTIVE NOT RECRUITING

A Phase 2 Clinical Study of MIL62 in Systemic Lupus Erythematosus

Beijing Mabworks Biotech Co., Ltd.

NCT05201469 RECRUITING

VIBRANT: VIB4920 for Active Lupus Nephritis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06625671 RECRUITING

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE Participants

DualityBio Inc.

NCT04629547 RECRUITING

Sleep Trial to Prevent Alzheimer's Disease

Washington University School of Medicine

NCT05237505 RECRUITING

The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)

University of California, San Diego

NCT06226077 RECRUITING

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

University of Minnesota

NCT06182969 RECRUITING

A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.

Ascentage Pharma Group Inc.

NCT07251452 ACTIVE NOT RECRUITING

Effectiveness of a Dual Program for Improving Sleep in Older Adults.

University of Castilla-La Mancha

NCT05558501 RECRUITING

Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities

VA Office of Research and Development

NCT06293365 ACTIVE NOT RECRUITING

Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

Novartis Pharmaceuticals

NCT06434363 RECRUITING

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

M.D. Anderson Cancer Center

NCT07229742 RECRUITING

A Phase II Clinical Study on the Efficacy and Safety of SHR-2173 Injection in the Treatment of Patients With Active Lupus Nephritis

Guangdong Hengrui Pharmaceutical Co., Ltd

NCT06587256 RECRUITING

Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.

Johns Hopkins University

NCT06189157 RECRUITING

MB-CART19.1 in Refractory SLE

Miltenyi Biomedicine GmbH

NCT07185269 RECRUITING

The Purpose of This Study is to Evaluate the Efficacy and Safety of 626 in the Treatment of SLE

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

NCT04534023 ACTIVE NOT RECRUITING

A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies

Ruijin Hospital

NCT06038474 ACTIVE NOT RECRUITING

Descartes-08 for Patients With Systemic Lupus Erythematosus

Cartesian Therapeutics

NCT07233252 RECRUITING

Nephron-sparing Treatment of Tislelizumab + Nab-Paclitaxel for Renal Pelvic Cancer

Tianjin Medical University Second Hospital

NCT07038382 RECRUITING

A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combination With Rituximab Injection Versus Placebo in Patients With Active Glomerulonephritis

Shanghai Henlius Biotech

NCT07225543 NOT YET RECRUITING

2-HOBA in Systemic Lupus Erythematosus

Vanderbilt University Medical Center

NCT06996652 NOT YET RECRUITING

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

Yale University

NCT07221968 NOT YET RECRUITING

Melatonin for the Treatment of DEE-SWAS

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

NCT06342960 ACTIVE NOT RECRUITING

KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Kyverna Therapeutics

NCT07061470 NOT YET RECRUITING

A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

NCT07221565 ENROLLING BY INVITATION

Quantum-Synaptic Immunotherapy Mapping Using Low-Frequency Electromagnetic Resonance and Machine Learning-Based Cytokine Forecasting

Truway Health, Inc.

NCT05938725 ACTIVE NOT RECRUITING

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Kyverna Therapeutics

NCT06226025 RECRUITING

Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder

Leslie Swanson

NCT04179032 ACTIVE NOT RECRUITING

Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

GlaxoSmithKline

NCT06776432 RECRUITING

Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea

Shionogi Apnimed Sleep Science

NCT05029336 RECRUITING

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

Stephan Grupp MD PhD

NCT05732402 ACTIVE NOT RECRUITING

An Open-label Study of Povetacicept in Autoantibody-Associated Glomerular Diseases

Alpine Immune Sciences, Inc.

NCT06687655 NOT YET RECRUITING

Impact of Exogenous Ketones on Sleep Apnea

Johns Hopkins University

NCT07198217 RECRUITING

Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient

Zibo Municipal Hospital

NCT06347718 RECRUITING

CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease

Miltenyi Biomedicine GmbH

NCT04486118 ACTIVE NOT RECRUITING

Centrally Acting ACE Inhibition in SLE

Northwell Health

NCT06585514 RECRUITING

Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus

Beijing GoBroad Hospital

NCT05282550 RECRUITING

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

Johns Hopkins University

NCT06971224 RECRUITING

NADream: Effects of Nicotinamide Adenine Dinucleotide Supplementation on Sleep Quality in Healthy Individuals

Haukeland University Hospital

NCT06477952 RECRUITING

DRonabinol Treatment of OSA

VA Office of Research and Development

NCT04857034 ACTIVE NOT RECRUITING

A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)

Bristol-Myers Squibb

NCT06599658 RECRUITING

COVID-19 Booster and IIV Schedule in Immunocompromised Hosts

McGill University Health Centre/Research Institute of the McGill University Health Centre

NCT06828042 RECRUITING

Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases

Peking University Third Hospital

NCT07125547 RECRUITING

Neoadjuvant Tislelizumab + Nab-Paclitaxel Followed by Distal Ureterectomy for Ureteral Cancer

Tianjin Medical University Second Hospital

NCT07053800 NOT YET RECRUITING

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis

Autolus Limited

NCT06266611 RECRUITING

Cannabis for Palliative Care in Cancer

University of Colorado, Boulder

NCT05966480 ACTIVE NOT RECRUITING

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

Alumis Inc

NCT07096557 RECRUITING

The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus

Ain Shams University

NCT06559163 RECRUITING

A Study of Obexelimab in Patients With Systemic Lupus Erythematosus

Zenas BioPharma (USA), LLC

NCT07089199 NOT YET RECRUITING

Tislelizumab Combined With Anlotinib and Nab-paclitaxel in III Resectable Non-small Cell Lung Cancer(TitAN) : A Prospective, Single-Arm, Phase II Study

Qilu Hospital of Shandong University

NCT05269628 RECRUITING

Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype

Tiffany J. Braley, MD, MS

NCT07085182 RECRUITING

Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer：A Prospective, Single-Arm, Phase II Study

Zibo Municipal Hospital

NCT07086456 RECRUITING

Combination of Concurrent Chemoradiotherapy With Surufatinib and Tislelizumab in Patients With Locally Advanced Non-Small Cell Lung Cancer

Sun Yat-sen University

NCT03673748 RECRUITING

Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells

Red de Terapia Celular

NCT05589753 RECRUITING

Sleep Disordered Breathing With Opioid Use

VA Office of Research and Development

NCT04868838 ACTIVE NOT RECRUITING

Daratumumab to Treat Active Lupus Nephritis

Mayo Clinic

NCT07044115 ACTIVE NOT RECRUITING

Evaluation of the Tolerance, Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of MIL62 Injection for Treating Lupus Nephritis

Beijing Mabworks Biotech Co., Ltd.

NCT05953610 RECRUITING

Endotypic Traits and Obstructive Sleep Apnea Surgery

University of California, Los Angeles

NCT07041801 RECRUITING

Treatment of Systemic Lupus Erythematosus With Human Umbilical Cord Mesenchymal Stem Cells

Shenzhen Beike Bio-Technology Co., Ltd.

NCT07000292 NOT YET RECRUITING

MSC303 Subcutaneous Injection for the Treatment of Immunologic Glomerular Disease.

Shanghai Changzheng Hospital

NCT05375734 RECRUITING

Phase II, Single-arm Exploratory Clinical Study of Tislelizumab Combined With Anlotinib in the Treatment of Advanced Pulmonary Pleomorphic Carcinoma

Second Affiliated Hospital of Nanchang University

NCT04895696 ACTIVE NOT RECRUITING

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Bristol-Myers Squibb

NCT06987565 NOT YET RECRUITING

Transcutaneous Vagus Nerve Stimulation in SLE

Northwell Health

NCT06971913 NOT YET RECRUITING

Efficacy and Safety of Low-dose IL-2 in SLE Patients With CMV Viremia

Peking University People's Hospital

NCT06970678 RECRUITING

Combining Dexmedetomidine Infusion and Paragastric Autonomic Neural Block to Enhance Postoperative Recovery in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Alexandria University

NCT06960200 RECRUITING

Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea

University of Alberta

NCT05538208 RECRUITING

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

Children's Hospital Medical Center, Cincinnati

NCT06043830 RECRUITING

Managing Opioid Related Sleep Apnea With Acetazolamide

University of California, San Diego

NCT06648681 NOT YET RECRUITING

Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients

University of British Columbia

NCT06043440 RECRUITING

Down Syndrome Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT06928766 NOT YET RECRUITING

Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty Sleeping

Flinders University

NCT06685042 RECRUITING

Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

NCT05904717 ACTIVE NOT RECRUITING

Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder

Syntara

NCT06649929 RECRUITING

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

University of Utah

NCT06794008 RECRUITING

BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases

Peking University People's Hospital

NCT06261021 RECRUITING

Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects with Discoid Lupus Erythematosus

Innovaderm Research Inc.

NCT06888973 ENROLLING BY INVITATION

Mesenchymal Stem Cells Infusion in Patients With Autoimmune Diseases

National Institute of Blood and Marrow Transplant (NIBMT), Pakistan

NCT06818981 ACTIVE NOT RECRUITING

Post-Operative Steroids After Sleep Surgery

Medical University of South Carolina

NCT06871527 NOT YET RECRUITING

Fruquintinib Combined With PD-1 Inhibitor and FOLFOX as First-Line Treatment For Advanced Gastric Cancer

Sixth Affiliated Hospital, Sun Yat-sen University

NCT06859931 NOT YET RECRUITING

Clinical Trial of TQB3702 Tablets in Subjects With Systemic Lupus Erythematosus (SLE)

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

NCT06841042 RECRUITING

A Study of SCTB35 in Patients with Systemic Lupus Erythematosus

Sinocelltech Ltd.

NCT06821659 NOT YET RECRUITING

Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined with Immunosuppressants in the Treatment of Refractory Autoimmune Diseases

Peking University Third Hospital

NCT05920863 RECRUITING

Lenvatinib Combined with Tislelizumab and TACE Applied As Neoadjuvant Regimen for the Patients of CNLC Stage IB and IIA Hepatocellular Carcinoma with High-risk Recurrence Factors

Zhejiang Cancer Hospital

NCT06286189 RECRUITING

Trazodone on OSA Endotypes

Brigham and Women's Hospital

NCT06672666 RECRUITING

Use of CBD in the Treatment of Anxiety

University of Florida

NCT06791772 NOT YET RECRUITING

Study of CM313(SC) Injection in Systemic Lupus Erythematosus(SLE)

Keymed Biosciences Co.Ltd

NCT06106893 RECRUITING

A Clinical Study of CD19 Universal CAR-γδT Cells in Active Systemic Lupus Erythematosus

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

NCT06106906 RECRUITING

A Clinical Study of CD19 CAR-T in Active Systemic Lupus Erythematosus

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

NCT06155604 RECRUITING

SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease

The University of Hong Kong

NCT03152058 RECRUITING

IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy

David Ware Branch

NCT00775476 RECRUITING

Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine

State University of New York - Upstate Medical University

NCT05804084 RECRUITING

Patient-centered and Neurocognitive Outcomes with Acetazolamide for Sleep Apnea

University of California, San Diego

NCT06675422 RECRUITING

JY231 Injection for the Treatment of Active Systemic Lupus Erythematosus (SLE)

920th Hospital of Joint Logistics Support Force of People's Liberation Army of China

NCT06428188 RECRUITING

Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases

Essen Biotech

NCT06667206 RECRUITING

Earlier Prime-BOOST Schedule to Improve MEasles Protection in High Burden Settings

University of Oxford

NCT05504187 NOT YET RECRUITING

Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Participants With Thrombotic Microangiopathy Secondary to Systemic Lupus Erythematosus

Kira Pharmacenticals (US), LLC.

NCT06350110 RECRUITING

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)

Essen Biotech

NCT05978505 RECRUITING

Reboxetine for Sleep Apnoea After ENT Surgery

Flinders University

NCT04875364 RECRUITING

Do Endotypes Predict Response and Sequelae in OSA Patients

University of California, San Diego

NCT06015230 ACTIVE NOT RECRUITING

Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GR1603 in SLE

Genrix (Shanghai) Biopharmaceutical Co., Ltd.

NCT05680480 RECRUITING

A Study of Telitacicept in Lupus Nephritis

RemeGen Co., Ltd.

NCT05933603 RECRUITING

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome

University of Arizona

NCT06249217 ACTIVE NOT RECRUITING

Good Nights Sleep Program to Improve Child and Family Sleep

Auburn University

NCT05688696 RECRUITING

Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Systemic Lupus Erythematosus

Beijing InnoCare Pharma Tech Co., Ltd.

NCT04903951 RECRUITING

Impact of Early Ventilation in Stroke Outcomes in Patients With Sleep Apnea After First Ever Stroke

Philips Portuguesa S.A.

NCT06535412 NOT YET RECRUITING

A Study of IMC-002 for the Treatment of Active Systemic Lupus Erythematosus

ImmuneCare Biopharmaceuticals (Shanghai) Co., Ltd.

NCT05293600 RECRUITING

Rescue Pharmacotherapy for OSA

Brigham and Women's Hospital

NCT05565833 RECRUITING

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

University of Virginia

NCT06290063 RECRUITING

Cannabidiol and Older Adult Cannabis Users

University of Colorado, Boulder

NCT06360068 NOT YET RECRUITING

A Prospective, Single Arm, Open Label, Proof of Concept Clinical Study of Sulfasalazine in the Treatment of Active Systemic Lupus Erythematosus

Qiong Fu

NCT06356740 NOT YET RECRUITING

Efficacy and Tolerance of Abacavir/Lamivudine Treatment in Patients With Systemic Lupus Erythematosus

Hospices Civils de Lyon

NCT06058078 RECRUITING

RY_SW01 Cell Injection Therapy in Active Lupus Nephritis

Jiangsu Renocell Biotech Company

NCT05970302 RECRUITING

XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

NCT05508009 RECRUITING

Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor

Alice Bertaina

NCT04736953 NOT YET RECRUITING

Sirolimus Treatment Of Patients With SLE

State University of New York - Upstate Medical University

NCT05841134 NOT YET RECRUITING

Tislelizumab Combined With Chemotherapy (CAPOX) in the Perioperative Treatment of MSI-H/dMMR Stage II or III Colorectal Cancer

The First Affiliated Hospital of Zhengzhou University

NCT03858751 RECRUITING

Pharmacological Activation of HMN for OSA Aim 2

Brigham and Women's Hospital

NCT03288324 COMPLETED

Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus

Children's Hospital Medical Center, Cincinnati

NCT05879718 TERMINATED

A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms.

Pfizer

NCT04883619 WITHDRAWN

A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis

Janssen Research & Development, LLC

NCT05629208 TERMINATED

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

Gilead Sciences

NCT05301894 TERMINATED

Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Neurocrine Biosciences

NCT02633163 COMPLETED

Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)

Medical University of South Carolina

NCT05789212 COMPLETED

A Personalized Mind-Body Intervention (MBI) for Improving Sleep Among Women Working in Healthcare

Northwell Health

NCT06404086 COMPLETED

RECOVER-SLEEP: Platform Protocol

Duke University

NCT04564339 TERMINATED

Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Alexion Pharmaceuticals, Inc.

NCT05589792 COMPLETED

Acetazolamide on REM OSA

Brigham and Women's Hospital

NCT04007796 COMPLETED

Apnea and Insomnia Relief Study

VA Office of Research and Development

NCT06785454 COMPLETED

A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension

Mineralys Therapeutics Inc.

NCT03995628 COMPLETED

Steroids and Pain Control After Tonsillectomy

Medical University of South Carolina

NCT06311500 COMPLETED

Sleep Health Enhancement in Midlife Adults

University of Kansas Medical Center

NCT03919955 COMPLETED

A Novel Pharmacological Therapy for Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT05810948 COMPLETED

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)

argenx

NCT07281105 COMPLETED

EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study

Evergreen Therapeutics, Inc.

NCT04882878 COMPLETED

A Study of Nipocalimab in Adult Participants With Active Systemic Lupus Erythematosus

Janssen Research & Development, LLC

NCT05781750 TERMINATED

A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

Kezar Life Sciences, Inc.

NCT05162586 COMPLETED

The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)

EMD Serono Research & Development Institute, Inc.

NCT05616260 COMPLETED

Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health

University of California, San Diego

NCT05951023 COMPLETED

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

University of California, San Diego

NCT04287062 COMPLETED

Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder

Johns Hopkins University

NCT05433857 COMPLETED

Probiotics in Systemic Lupus Erythematosus

Ain Shams University

NCT03393013 COMPLETED

A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis

Kezar Life Sciences, Inc.

NCT05591222 TERMINATED

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

Amgen

NCT02770170 COMPLETED

Dose Finding, Efficacy and Safety of BI 655064 in Patients With Active Lupus Nephritis

Boehringer Ingelheim

NCT05097989 TERMINATED

Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Alexion Pharmaceuticals, Inc.

NCT03656562 COMPLETED

Study the Efficacy and Safety of VAY736 and CFZ533 in SLE Patients

Novartis Pharmaceuticals

NCT02472795 COMPLETED

Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of ACT-334441 in Subjects With Systemic Lupus Erythematosus

Viatris Innovation GmbH

NCT03742037 COMPLETED

Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

Viatris Innovation GmbH

NCT03030118 COMPLETED

Study of Anti-Malarials in Incomplete Lupus Erythematosus

Milton S. Hershey Medical Center

NCT05814016 TERMINATED

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery

Takeda

NCT03948074 COMPLETED

Cannabis For Cancer-Related Symptoms

Pippa Hawley

NCT05306873 TERMINATED

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04398706 COMPLETED

Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

Sanofi Pasteur, a Sanofi Company

NCT04625101 COMPLETED

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Neurocrine Biosciences

NCT04781816 COMPLETED

Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus

Sanofi

NCT05000216 TERMINATED

COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04932096 COMPLETED

Sleep Management And Recovery After Traumatic Brain Injury in Kids: Pilot Intervention of Melatonin

Oregon Health and Science University

NCT04115878 COMPLETED

Medications for Obstructive Sleep Apnea In Children With Down Syndrome

University of Arizona

NCT04835441 COMPLETED

ALPN-101 (Acazicolcept) in Systemic Lupus Erythematosus

Alpine Immune Sciences Inc, A Subsidiary of Vertex

NCT02484716 COMPLETED

Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)

Hospices Civils de Lyon

NCT06161116 TERMINATED

Efficacy And Safety Of MK-6194 In Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)

Merck Sharp & Dohme LLC

NCT03954782 COMPLETED

Efficacy of Nintedanib Per os as a Treatment for Epistaxis in HHT Disease.

Hospices Civils de Lyon

NCT05594589 COMPLETED

A Study to Assess the Pharmacodynamics of Lemborexant in Korean Participants With Insomnia Disorder

Eisai Co., Ltd.

NCT05630846 COMPLETED

A Study on the Immune Response and Safety of a Combined Measles, Mumps, Rubella, Chickenpox Vaccine Compared to a Marketed Combined Vaccine, Given to Healthy Children 4 to 6 Years of Age

GlaxoSmithKline

NCT04908280 COMPLETED

Study of Ruxolitinib Cream for the Treatment of Discoid Lupus Erythematosus

University of Rochester

NCT05087628 TERMINATED

PRV-3279-2a Trial in Systemic Lupus

Provention Bio, a Sanofi Company

NCT03189173 COMPLETED

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT04886518 COMPLETED

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Harmony Biosciences Management, Inc.

NCT06419205 WITHDRAWN

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

Q32 Bio Inc.

NCT05841979 COMPLETED

The Lived Experiences Measured Using Rings Pilot Study

University of Vermont

NCT03920267 COMPLETED

Long-Term Safety and Efficacy Study of Deucravacitinib in Participants With Systemic Lupus Erythematosus

Bristol-Myers Squibb

NCT05638802 COMPLETED

A Study of DS-7011a in Patients With Systemic Lupus Erythematosus

Daiichi Sankyo

NCT04376827 TERMINATED

A Study of Guselkumab in Participants With Active Lupus Nephritis

Janssen Research & Development, LLC

NCT05540665 TERMINATED

Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN)

Amgen

NCT03675282 COMPLETED

Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls

Weill Medical College of Cornell University

NCT03194217 COMPLETED

BEN-2001 in Parkinson Disease Patients With Excessive Daytime Sleepiness

BenevolentAI Bio

NCT03958955 TERMINATED

Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.

LEO Pharma

NCT03453619 COMPLETED

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

Apellis Pharmaceuticals, Inc.

NCT06153095 WITHDRAWN

A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE)

Lyell Immunopharma, Inc.

NCT05123586 TERMINATED

A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus

Eli Lilly and Company

NCT04451772 COMPLETED

A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State

AbbVie

NCT03308578 COMPLETED

Statins and CPAP in Adipose Tissue of OSA

Mayo Clinic

NCT04077684 COMPLETED

Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter, Randomised, Placebo-controlled Trial

Peking University People's Hospital

NCT04928157 COMPLETED

Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids

University of California, San Diego

NCT04643470 COMPLETED

Zanubrutinib in Participants With Active Proliferative Lupus Nephritis

BeiGene

NCT05714670 COMPLETED

The Effect of Curcumin on the Clinical Outcome of Pediatric Patients with Active Lupus Nephritis

Ain Shams University

NCT04883346 COMPLETED

Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT04211870 COMPLETED

Effects of Photobiomodulation in Children With Down Syndrome and Possible Sleep Bruxism

University of Nove de Julho

NCT05244226 COMPLETED

Pediatric Pain Optimization After Tonsillectomy

Duke University

NCT06570434 WITHDRAWN

Phase 1b/2a in SLE With Budoputug

Tenet Medicines

NCT03610516 COMPLETED

Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

Novartis Pharmaceuticals

NCT03355053 COMPLETED

Investigation of Sleep in the Intensive Care Unit

Massachusetts General Hospital

NCT04262193 TERMINATED

Dual-Orexin Antagonism As a Mechanism for Improving Sleep and Drug Abstinence in Opioid Use Disorder

Wayne State University

NCT04058028 COMPLETED

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Amgen

NCT05430854 TERMINATED

Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension Study

Amgen

NCT03049306 COMPLETED

Propranolol for Sleep Apnea Therapy

Johns Hopkins University

NCT03845517 COMPLETED

A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Pfizer

NCT02550652 COMPLETED

A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)

Hoffmann-La Roche

NCT04925934 COMPLETED

Study of VIB7734 for the Treatment of Moderate to Severely Active SLE

Amgen

NCT04680637 TERMINATED

Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus

Amgen

NCT04639193 COMPLETED

Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea

University of California, San Diego

NCT04643067 COMPLETED

Phase 1b/2a Study to Evaluate Safety and Efficacy of KPG-818 in SLE

Kangpu Biopharmaceuticals, Ltd.

NCT05097651 WITHDRAWN

CBD for Sleep in People With HIV

Mariana Cherner, PhD

NCT02908100 COMPLETED

A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus

Genentech, Inc.

NCT04433585 COMPLETED

A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE)

Nektar Therapeutics

NCT04767997 COMPLETED

Probiotics on Sleep Among Adults Study

Lallemand Health Solutions

NCT03355482 TERMINATED

MRI Evaluation Assessing Synovitis to Address the Unmet Need for Reliable Endpoints in SLE

Oklahoma Medical Research Foundation

NCT04186871 COMPLETED

Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Bristol-Myers Squibb

NCT05236842 COMPLETED

Efficacy, Safety and Tolerability of Sulthiame in Patients With Obstructive Sleep Apnea (OSA)

Desitin Arzneimittel GmbH

NCT05793684 COMPLETED

AD816 Crossover Study

Apnimed

NCT02847598 COMPLETED

Study to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)

Biogen

NCT03951259 COMPLETED

Safety and Efficacy of SM934 Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

RenJi Hospital

NCT05278663 COMPLETED

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of E6742 in Systemic Lupus Erythematosus Participants

Eisai Co., Ltd.

NCT04445688 COMPLETED

Crossover Trial of AD036 in Obstructive Sleep Apnea

Apnimed

NCT05101447 WITHDRAWN

Pharmacokinetically-driven Dosing of Mycophenolate Mofetil for the Treatment of Pediatric Proliferative Lupus Nephritis

Children's Hospital Medical Center, Cincinnati

NCT03881852 COMPLETED

Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment (CONCERT)

Axsome Therapeutics, Inc.

NCT04905979 COMPLETED

Trial of AD113 and Atomoxetine in OSA Patients With Hypertension

Apnimed

NCT05253417 COMPLETED

The CANabidiol Use for RElief of Short Term Insomnia

Bod Australia

NCT03978520 COMPLETED

A Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)

AbbVie

NCT05303935 COMPLETED

Effects of Quetiapine on Sleep and Next Day Alertness in People With Obstructive Sleep Apnea

Flinders University

NCT05921058 COMPLETED

The Effects of Mesenchymal Stem Cell Secretome in Lupus Patients

Universitas Sebelas Maret

NCT03161483 COMPLETED

A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus

Celgene

NCT04872816 COMPLETED

Obstructive Sleep Apnea and Telomere Length

Associação Fundo de Incentivo à Pesquisa

NCT05101122 COMPLETED

Study for Efficacy and Dose Escalation of AD313 + Atomoxetine (SEED)

Apnimed

NCT04394689 COMPLETED

Measles and Rubella Vaccine Microneedle Patch Phase 1-2 Age De-escalation Trial

Micron Biomedical, Inc

NCT03959202 COMPLETED

A Personalized Behavioral Intervention to Improve Physical Activity, Sleep and Cognition in Sedentary Older Adults

Johns Hopkins University

NCT03148899 COMPLETED

Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep

George Washington University

NCT04580394 COMPLETED

Crossover Trial of AD109 in Obstructive Sleep Apnea

Apnimed

NCT03025464 TERMINATED

Validation of Sleep Apnea Screening Device Phase II

University of Michigan

NCT04530747 TERMINATED

Metabolic Effects of Metformin Therapy in Obstructive Sleep Apnea

Pennington Biomedical Research Center

NCT03845023 COMPLETED

Trial of AD036 in Obstructive Sleep Apnea

Apnimed

NCT02962960 COMPLETED

A Study to Characterize the Pharmacokinetics, Pharmacodynamics, and Safety of Anifrolumab in Adult Type I Interferon Test High Systemic Lupus Erythematosus Subject With Active Skin Manifestations

AstraZeneca

NCT04631107 COMPLETED

AD109 Dose Finding in Mild to Moderate OSA

Apnimed

NCT03252587 COMPLETED

An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus Erythematosus

Bristol-Myers Squibb

NCT05071612 COMPLETED

Parallel Arm Trial of AD109 and AD504 In Patients With OSA

Apnimed

NCT04305197 COMPLETED

A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)

Beijing InnoCare Pharma Tech Co., Ltd.

NCT03093402 COMPLETED

JBT-101 in Systemic Lupus Erythematosus (SLE)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04713826 COMPLETED

A Trial to Learn More About How Well BAY2586116 Works and How Safe it is in Participants With Moderate to Severe Obstructive Sleep Apnea

Bayer

NCT03943147 TERMINATED

An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis

Bristol-Myers Squibb

NCT05535179 COMPLETED

Effect of Gargle Containing Honeysuckle and Semen Oroxyli

Hubei Hospital of Traditional Chinese Medicine

NCT04645524 COMPLETED

Crossover Trial of AD182 and AD504 in Obstructive Sleep Apnea

Apnimed

NCT04923594 COMPLETED

Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in the Treatment of Narcolepsy

NLS Pharmaceutics

NCT03789214 COMPLETED

Medical Management of Sleep Disturbance During Opioid Tapering

Johns Hopkins University

NCT04236440 COMPLETED

Study on the Safety of Drug BAY2586116 and How it Works in Patients With Obstructive Sleep Apnea (a Sleep Disorder Caused by the Narrowing and Collapse of the Airway During Sleep) Including the Blood Level of the Drug and Effect of Its Doses and Routes of Administration

Bayer

NCT03953261 TERMINATED

Effect of Curcumin on Systemic Lupus Erythematosus

Loma Linda University

NCT03385564 COMPLETED

An Exploratory Maintenance Trial of BI 655064 in Patients With Lupus Nephritis

Boehringer Ingelheim

NCT05430087 COMPLETED

Vitamin D and Curcumin Piperine Attenuates Disease Activity and Cytokine Levels in Systemic Lupus Erythematosus Patients

Saiful Anwar Hospital

NCT05430685 COMPLETED

The Impact of Ashwagandha on Perceived Stress, Sleep and Food Cravings in College Students

University of Colorado, Colorado Springs

NCT02677688 TERMINATED

Autologous EBV-specific Cytotoxic T Cells for the Treatment of Systemic Lupus Erythematosus (SLE)

Nantes University Hospital

NCT03371251 COMPLETED

Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care

Boston Pharmaceuticals

NCT03892772 COMPLETED

Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT02259725 COMPLETED

Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors

University of Southern California

NCT02547922 COMPLETED

Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis

AstraZeneca

NCT04449133 COMPLETED

Study of AD128 Versus Placebo in Obstructive Sleep Apnea

Istituto Auxologico Italiano

NCT02338999 COMPLETED

Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT03866317 WITHDRAWN

A Study to Assess the Safety and Efficacy of Secukinumab in Alleviating Symptoms of Discoid Lupus Erythematosus

Massachusetts General Hospital

NCT03152864 COMPLETED

Stabilizing Behavioral Rhythms to Improve Mental Health

HealthRhythms, Inc.

NCT02804763 COMPLETED

A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus

UCB Biopharma S.P.R.L.

NCT03001557 COMPLETED

Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia

Eisai Inc.

NCT02429934 TERMINATED

Abatacept for SLE Arthritis (IM101-330)

University of California, Los Angeles

NCT02975336 TERMINATED

A Phase II Study of M2951 in SLE

EMD Serono Research & Development Institute, Inc.

NCT02543203 COMPLETED

Essential Oils for Enhancing QOL in ASD

Jill Hollway

NCT02949973 COMPLETED

Aurinia Early Urinary Protein Reduction Predicts Response

Aurinia Pharmaceuticals Inc.

NCT02660944 COMPLETED

A Phase 2a of RSLV-132 in Subjects With Systemic Lupus Erythematosus (SLE)

Resolve Therapeutics

NCT04184258 COMPLETED

Treatment of Systemic Lupus Erythematosus With Pooled Allogenic Mesenchymal Stem Cells

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

NCT02806895 COMPLETED

Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in OSA

Jazz Pharmaceuticals

NCT02806908 COMPLETED

Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy

Jazz Pharmaceuticals

NCT03407482 TERMINATED

An Extension Study of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus

Genentech, Inc.

NCT03603678 COMPLETED

Obstructive Sleep Apnea (OSA) Treated With a Potassium Channel Inhibitor

Bayer

NCT02260934 COMPLETED

Rituximab and Belimumab for Lupus Nephritis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03042780 TERMINATED

FOLFIRINOX in Metastatic High Grade Gastroenteropancreatic Neuroendocrine Carcinomas

H. Lee Moffitt Cancer Center and Research Institute

NCT03601169 COMPLETED

Comparison of MMFS Dosages in Older Adults

Neurocentria, Inc.

NCT03312335 COMPLETED

Low-dose Interleukin-2 for Treatment of Systemic Lupus Erythematosus

Onur Boyman, MD

NCT04167475 COMPLETED

Effect of B. Longum 1714™ on Sleep Quality

PrecisionBiotics Group Ltd.

NCT03134222 COMPLETED

Study to Evaluate Safety and Efficacy of Filgotinib and Lanraplenib in Females With Moderately-to-Severely Active Cutaneous Lupus Erythematosus (CLE)

Gilead Sciences

NCT02708186 COMPLETED

Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)

Axovant Sciences Ltd.

NCT03285711 COMPLETED

Study to Evaluate the Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)

Gilead Sciences

NCT02665364 TERMINATED

Phase IIb Study of IFN-K in Systemic Lupus Erythematosus

Neovacs

NCT02349061 COMPLETED

A Phase 2a, Efficacy and Safety Study of Ustekinumab in Systemic Lupus Erythematosus

Janssen Research & Development, LLC

NCT02885610 COMPLETED

Study of RC18 Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus(SLE)

RemeGen Co., Ltd.

NCT02917265 TERMINATED

Transcutaneous Vagus Nerve Stimulation for the Treatment of Lupus

Aikaterini Thanou

NCT03383887 COMPLETED

DAW1033D in Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT03640052 COMPLETED

Pharmacological Activation of HMN for OSA

Brigham and Women's Hospital

NCT03426631 COMPLETED

DAW1033B2 in Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT02554019 COMPLETED

Proof-of-Concept Study With BT063 in Subjects With Systemic Lupus Erythematosus

Biotest

NCT03037203 COMPLETED

A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

Jazz Pharmaceuticals

NCT02418273 WITHDRAWN

Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders

Indiana University

NCT02080195 TERMINATED

Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE)

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02818569 COMPLETED

Repurposing Dexmedetomidine as an Orally Administered Sleep Therapeutic

Massachusetts General Hospital

NCT02725515 COMPLETED

A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus

Xencor, Inc.

NCT02871427 TERMINATED

Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

Axovant Sciences Ltd.

NCT02955615 COMPLETED

ILT-101 in Patients With Active Moderate to Severe Systemic Lupus Erythematosus (SLE)

Iltoo Pharma

NCT02656082 COMPLETED

Targeted Therapy Using Intradermal Injection of Etanercept for Remission Induction in Discoid Lupus Erythematosus

University of Leeds

NCT02437890 COMPLETED

A Phase II Study to Evaluate Safety and Efficacy of ALX-0061 in Subjects With Systemic Lupus Erythematosus

Ablynx, a Sanofi company

NCT02908529 COMPLETED

Atomoxetine and Oxybutynin in Obstructive Sleep Apnea

Brigham and Women's Hospital

NCT02708095 COMPLETED

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus (SLE)

Eli Lilly and Company

NCT02533570 TERMINATED

Dose Ranging Study of Brentuximab Vedotin in Adults With Lupus

Seagen Inc.

NCT02711813 TERMINATED

TAB08 in Patients With Systemic Lupus Erythematosus (SLE), Not Adequately Controlled With Current Treatment

Theramab LLC

NCT02320357 COMPLETED

Pilot Study Related to the Effect of Clopidogrel on Plasmatic Soluble CD40 Ligand During Systemic Lupus Erythematous

University Hospital, Bordeaux

NCT02387710 COMPLETED

Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea

Brigham and Women's Hospital

NCT02656160 COMPLETED

Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults

Brigham and Women's Hospital

NCT02438137 COMPLETED

Dimethyl Fumarate for Obstructive Sleep Apnea

University of Michigan

NCT02428478 COMPLETED

Effect of Desipramine on Genioglossus Muscle Activity in Healthy Adults Study A

Brigham and Women's Hospital

NCT02436031 COMPLETED

Effect of Desipramine on Upper Airway Collapsibility and Genioglossus Muscle Activity in Patients With Obstructive Sleep Apnea - Study B

Brigham and Women's Hospital

NCT02949349 COMPLETED

Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis

Genovate Biotechnology Co., Ltd.,

NCT02875691 COMPLETED

Effect of Green Tea on Treatment of Lupus

Ahvaz Jundishapur University of Medical Sciences

NCT02312908 COMPLETED

Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism

Seoul National University Hospital

NCT07262983 RECRUITING

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03816345 RECRUITING

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT07236762 RECRUITING

An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases

China Immunotech (Beijing) Biotechnology Co., Ltd.

NCT06013995 RECRUITING

A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus

Bristol-Myers Squibb

NCT07236801 RECRUITING

Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases

China Immunotech (Beijing) Biotechnology Co., Ltd.

NCT07104721 RECRUITING

A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases

China Immunotech (Beijing) Biotechnology Co., Ltd.

NCT07123519 RECRUITING

A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases

China Immunotech (Beijing) Biotechnology Co., Ltd.

NCT07444307 RECRUITING

A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus

Hangzhou Qihan Biotech Co., Ltd.

NCT06335979 RECRUITING

An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE).

Novartis Pharmaceuticals

NCT07439029 NOT YET RECRUITING

YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases

Children's Hospital of Fudan University

NCT06333483 RECRUITING

Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus

Autolus Limited

NCT07432334 NOT YET RECRUITING

CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus

Vinmec Research Institute of Stem Cell and Gene Technology

NCT07219563 RECRUITING

Alnuctamab for Refractory SLE (LATTE Study)

Icahn School of Medicine at Mount Sinai

NCT07363590 RECRUITING

A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)

Merck Sharp & Dohme LLC

NCT06152172 ACTIVE NOT RECRUITING

CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101

David Porter

NCT07413341 RECRUITING

A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases

Therorna

NCT07201558 RECRUITING

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

AstraZeneca

NCT05289063 RECRUITING

Vascular Endothelial Dysfunction in Sleep Apnea

Columbia University

NCT07408908 NOT YET RECRUITING

Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic (PK/PD) Profile of ACT100 in Healthy Participants..

Xiamen Amoytop Biotech Co., Ltd.

NCT06977724 RECRUITING

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE) and Sjogren's Disease (SjD)

AbbVie

NCT06916806 RECRUITING

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

AstraZeneca

NCT07403097 RECRUITING

Study of CD19 CAR-T Therapy for Refractory SLE

Chongqing Precision Biotech Co., Ltd

NCT05835986 RECRUITING

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Hoffmann-La Roche

NCT06308978 RECRUITING

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

Fate Therapeutics

NCT06647069 RECRUITING

DR-0201 in Subjects With Autoimmune Diseases

Dren Bio

NCT07085104 RECRUITING

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

Allogene Therapeutics

NCT06222853 ACTIVE NOT RECRUITING

Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cells in Refractory Systemic Lupus Erythematosus

The Children's Hospital of Zhejiang University School of Medicine

NCT07387705 NOT YET RECRUITING

On Track for Wellness (OTW) Stepped Wedge Cluster Randomized Trial

University of Illinois at Chicago

NCT07305116 RECRUITING

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

The Children's Hospital of Zhejiang University School of Medicine

NCT07318259 RECRUITING

Study of Ultra-Fast BCMA/CD70 CAR-T Therapy for Refractory SLE

Chongqing Precision Biotech Co., Ltd

NCT06984341 NOT YET RECRUITING

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)

Genentech, Inc.

NCT07331272 RECRUITING

A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)

Nanjing Legend Biotech Co.

NCT07371468 NOT YET RECRUITING

A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)

GlaxoSmithKline

NCT07306585 NOT YET RECRUITING

The Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HC022 Injection in Subjects With SLE/CLE

HC Biopharma Inc.

NCT07109986 RECRUITING

UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis

Nanjing IASO Biotechnology Co., Ltd.

NCT07361094 RECRUITING

Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases

Beijing Boren Hospital

NCT07358988 NOT YET RECRUITING

KN5501 Cell Injection for Refractory SLE(CLEAR)

Ruitherapeutics Co., LTD

NCT06975787 RECRUITING

Dose Escalation Study With Bispecific Antibodies in Adult Patients With Lupus Nephritis

Regeneron Pharmaceuticals

NCT07315087 RECRUITING

CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases

Institute of Hematology & Blood Diseases Hospital, China

NCT07224074 RECRUITING

Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)

Johns Hopkins University

NCT05869955 RECRUITING

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

NCT07331467 RECRUITING

Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE

Chongqing Precision Biotech Co., Ltd

NCT07038447 ENROLLING BY INVITATION

A Study of KITE-363 in Participants With Refractory Autoimmune Diseases

Kite, A Gilead Company

NCT06913608 NOT YET RECRUITING

A Study to Assess CLBR001+SWI019 in Subjects With Autoimmune Diseases

Calibr, a division of Scripps Research

NCT06255028 ACTIVE NOT RECRUITING

A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases

Century Therapeutics, Inc.

NCT07323173 RECRUITING

A Phase I Study to Assess LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus

Nanjing Leads Biolabs Co.,Ltd

NCT07011043 RECRUITING

A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)

Climb Bio, Inc.

NCT06064929 ACTIVE NOT RECRUITING

A Study to Learn More About the Safety and Effects of Felzartamab in Adults With Lupus Nephritis Aged 18 to 75 Years Old

HI-Bio, A Biogen Company

NCT06530849 RECRUITING

A Study of GC012F Injection in Subjects With Refractory Systemic Lupus Erythematosus

Gracell Biotechnologies (Shanghai) Co., Ltd.

NCT07082829 RECRUITING

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

Centessa Pharmaceuticals (UK) Limited

NCT06892145 RECRUITING

Clinical Trial of CD19 Targeted CAR-T Cell in Refractory Adult SLE

Chongqing Precision Biotech Co., Ltd

NCT07167316 NOT YET RECRUITING

The Role of the LC-NA System in Experimental Sleep Fragmentation

Hans-Peter Landolt

NCT06925542 RECRUITING

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

CRISPR Therapeutics

NCT06465147 RECRUITING

REACT-01: Reversing Autoimmunity Through Cell Therapy

Seattle Children's Hospital

NCT06576271 RECRUITING

A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants and Healthy Chinese and Japanese Participants

GlaxoSmithKline

NCT07276958 NOT YET RECRUITING

A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

Eli Lilly and Company

NCT06265220 ACTIVE NOT RECRUITING

AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus

Artiva Biotherapeutics, Inc.

NCT06789107 RECRUITING

Blinatumomab in Refractory Active Childhood Systemic Lupus Erythematosus

Mao Jianhua

NCT06613360 RECRUITING

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

Cullinan Therapeutics Inc.

NCT06294236 ACTIVE NOT RECRUITING

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM)

Sana Biotechnology

NCT07031713 RECRUITING

Safety, Efficacy and Cellular Metabolic Dynamics of ct1192 in Patients With Moderate to Severe Refractory SLE

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

NCT07237659 RECRUITING

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

Neutrolis

NCT07233642 RECRUITING

Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE

The Children's Hospital of Zhejiang University School of Medicine

NCT07215663 RECRUITING

Clinical Study of Cizutamig in Systemic Lupus Erythematosus

Candid Therapeutics

NCT06544330 ACTIVE NOT RECRUITING

A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease

Synthekine

NCT06941129 RECRUITING

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases

Institute of Hematology & Blood Diseases Hospital, China

NCT05411016 ACTIVE NOT RECRUITING

A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus

Kyowa Kirin Co., Ltd.

NCT06400537 RECRUITING

Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

NCT07177911 RECRUITING

Safety and Efficacy Study of CC312 for Moderate to Severe SLE

CytoCares Inc

NCT06799520 RECRUITING

A Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of VIS171 in Participants With Autoimmune Disease(s)

Otsuka Pharmaceutical Development & Commercialization, Inc.

NCT06822881 RECRUITING

CT1190B in the Treatment of Patients With Moderate to Severe Refractory Systemic Lupus Erythematosus (SLE) or Refractory/Progressive Systemic Sclerosis (SSc)

Beijing GoBroad Hospital

NCT03142893 ACTIVE NOT RECRUITING

Hormonal Mechanisms of Sleep Restriction - Axis Study

Peter y. Liu

NCT06737380 RECRUITING

UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

LiveKidney.Bio

NCT07136389 RECRUITING

Safety, Pharmacokinetics, Immunogenicity BCD-256-1 and Divozilimab in Subjects With Systemic Lupus Erythematosus

Biocad

NCT05497180 RECRUITING

Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea

University of Alberta

NCT06375993 RECRUITING

A Phase 1 Study of ADI-001 in Autoimmune Disease

Adicet Therapeutics

NCT06249438 RECRUITING

A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

RenJi Hospital

NCT06518668 RECRUITING

A Study of NKX019, a CD19 CAR NK Cell Therapy, in Subjects With Systemic Lupus Erythematosus

Columbia University

NCT07085676 RECRUITING

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Polina Stepensky

NCT06978647 RECRUITING

A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases

China Immunotech (Beijing) Biotechnology Co., Ltd.

NCT06881290 RECRUITING

Vunakizumab for the Treatment of Mild to Moderate Systemic Lupus Erythematosus

Chinese SLE Treatment And Research Group

NCT06144710 RECRUITING

SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus

Hangzhou Sumgen Biotech Co., Ltd.

NCT06857214 RECRUITING

A Study of GNC-038 Tetra-specific Antibody Injection in Patients With Systemic Lupus Erythematosus

Sichuan Baili Pharmaceutical Co., Ltd.

NCT06285279 RECRUITING

The BCMA/CD19 Dual Targeted CAR-T Cell in Participants With Autoimmune Kidney Diseases

Nanjing University School of Medicine

NCT07001839 NOT YET RECRUITING

A Phase Ib Study of QLS4131 in Subjects With Systemic Lupus Erythematosus

Qilu Pharmaceutical Co., Ltd.

NCT06340750 RECRUITING

BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus

Luminary Therapeutics

NCT06676631 RECRUITING

NK010 or NK042 in Combination With Rituximab for Refractory Systemic Lupus Erythematosus/Lupus Nephritis

Guangdong Provincial People's Hospital

NCT06710717 RECRUITING

Autologous CD19 Car T-Cell Therapy For Severe Refractory Systemic Lupus Erythematosus (SLE)

National University of Malaysia

NCT06644573 NOT YET RECRUITING

Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia

Nyree Penn

NCT06421701 RECRUITING

Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus

Second Affiliated Hospital, School of Medicine, Zhejiang University

NCT06980597 RECRUITING

A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases

Beijing GoBroad Hospital

NCT06978738 NOT YET RECRUITING

UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases

Changzhou No.2 People's Hospital

NCT06943937 RECRUITING

A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus

China Immunotech (Beijing) Biotechnology Co., Ltd.

NCT06960161 RECRUITING

Exploring the Use of Phototherapy to Improve CPAP Compliance

University of Alberta

NCT06945068 NOT YET RECRUITING

An Open-label Study of GB261 in Refractory Seropositive Systemic Lupus Erythematosus

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

NCT06934447 RECRUITING

Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE

The Children's Hospital of Zhejiang University School of Medicine

NCT06657703 RECRUITING

Safety, Tolerability, and Pharmacokinetics of Single Doses of HC022 in Healthy Subjects.

HC Biopharma Inc.

NCT05018858 RECRUITING

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Lupus

The Foundation for Orthopaedics and Regenerative Medicine

NCT06349343 RECRUITING

CD19/BCMA CAR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

NCT03860233 RECRUITING

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Vivek Jain

NCT06852573 NOT YET RECRUITING

Clinical Study of ZM001 Injection in the Treatment of Refractory Systemic Lupus Erythematosus

Beijing Immunochina Medical Science & Technology Co., Ltd.

NCT05866861 ACTIVE NOT RECRUITING

A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus

Cugene Inc.

NCT05094271 RECRUITING

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

University of California, San Diego

NCT04478305 RECRUITING

Affect of Duavive on Mood & Anxiety Symptoms

St. Joseph's Healthcare Hamilton

NCT06708845 NOT YET RECRUITING

US Zamto-cel Autoimmune Diseases

Miltenyi Biomedicine GmbH

NCT06694298 NOT YET RECRUITING

A Study of SYS6020 Injection in Refractory Active Systemic Lupus Erythematosus

CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

NCT06691152 RECRUITING

Efficacy and Safety of CD19 UCAR T Cells in Refractory Systemic Lupus Erythematosus

The Children's Hospital of Zhejiang University School of Medicine

NCT05687526 RECRUITING

A Study of Telitacicept in Subjects With Childhood-onset Systemic Lupus Erythematosus

RemeGen Co., Ltd.

NCT06581562 RECRUITING

Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.

IRIS Research and Development, LLC

NCT06567080 NOT YET RECRUITING

JWCAR201 for the Treatment of Hematology Malignancy and Autoimmune Diseases

RenJi Hospital

NCT06448273 RECRUITING

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacokinetic of TQB3702 Tablets in Healthy Adult Subjects

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

NCT06468683 NOT YET RECRUITING

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Shanghai Simnova Biotechnology Co.,Ltd.

NCT06373991 NOT YET RECRUITING

A Study to Evaluate the Safety and Efficacy of ATHENA CAR-T in Subjects With Systemic Lupus Erythematosus

EdiGene Inc.

NCT06340490 NOT YET RECRUITING

A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE)

Guangdong Ruishun Biotech Co., Ltd

NCT06316076 RECRUITING

Safety and Efficacy Study of CD19-CAR-DNT Cells in Autoimmune Diseases

RenJi Hospital

NCT06297408 NOT YET RECRUITING

Relma-cel for Moderate to Severe Active Systemic Lupus Erythematosus

Shanghai Ming Ju Biotechnology Co., Ltd.

NCT04976465 RECRUITING

Treatment and Clinical Outcomes Among SLE Patients in Pregnancy

Qilu Hospital of Shandong University

NCT04906044 ACTIVE NOT RECRUITING

Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer

The First Hospital of Jilin University

NCT06056921 RECRUITING

Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease

Chongqing Precision Biotech Co., Ltd

NCT05973734 NOT YET RECRUITING

Islet Transplantation With Recipient T-Reg Cells or Deceased Donor Vertebral Bone Marrow Therapy

Stanford University

NCT06935123 COMPLETED

Impact of Nutritional Supplementation on Sleep Quality

Pharmavite LLC

NCT06955598 COMPLETED

A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Subcutaneous Injections of SHR-2173 in Patients With Systemic Lupus Erythematosus

Guangdong Hengrui Pharmaceutical Co., Ltd

NCT05917288 COMPLETED

A Study of Belimumab in Chinese Pediatric Participants With Systemic Lupus Erythematosus

GlaxoSmithKline

NCT06655649 SUSPENDED

Impact of Exogenous Ketones on Sleep Disruption in Vulnerable Populations

Johns Hopkins University

NCT06188507 SUSPENDED

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

GlaxoSmithKline

NCT06752876 WITHDRAWN

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)

Caribou Biosciences, Inc.

NCT05048238 COMPLETED

Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04611763 COMPLETED

Effect of Preemptive Analgesia With Flurbiprofen Axetil on Perioperative Sleep Quality and Postoperative Pain in Patients Undergoing Laparoscopic Gynecological Surgery.

Beijing Friendship Hospital

NCT04721691 COMPLETED

Efficacy of Epidiolex in Patients With Electrical Status Epilepticus of Sleep (ESES).

Northwell Health

NCT05592379 COMPLETED

Consciousness, Psilocybin, and Well-Being

University of Wisconsin, Madison

NCT05155345 COMPLETED

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered Mosunetuzumab to Participants With Systemic Lupus Erythematosus

Hoffmann-La Roche

NCT03796026 COMPLETED

A Study to Assess the Effect of Seltorexant Compared to Placebo on Respiration During Sleep in Adult Participants With Obstructive Sleep Apnea

Janssen Research & Development, LLC

NCT06429800 WITHDRAWN

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Systemic Lupus Erythematosus

Atara Biotherapeutics

NCT04128579 COMPLETED

Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis

Equillium

NCT06377228 WITHDRAWN

A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN) or Refractory Systemic Sclerosis (SSc)

Takeda

NCT06238531 WITHDRAWN

A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Systemic Lupus Erythematosus (SLE) or Lupus

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT04746105 COMPLETED

A Clinical Pharmacology Study of TS-142 in Patients with Obstructive Sleep Apnea Hypopnea.

Taisho Pharmaceutical Co., Ltd.

NCT05328557 COMPLETED

A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers

Cugene Inc.

NCT06041568 TERMINATED

A Study of Imvotamab in Severe Systemic Lupus Erythematosus

IGM Biosciences, Inc.

NCT02609789 COMPLETED

A Single Ascending Dose Study in Healthy Participants and Multiple Dose Study of JNJ-55920839 in Participants With Mild to Moderate Systemic Lupus Erythematosus

Janssen Research & Development, LLC

NCT06411639 WITHDRAWN

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Novartis Pharmaceuticals

NCT05857384 COMPLETED

Bioavailability, Bioequivalence and Tolerability of IHL-42X Compared to the Reference Drugs

Incannex Healthcare Ltd

NCT02780674 COMPLETED

A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases

Amgen

NCT03817424 COMPLETED

A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis

Amgen

NCT03882801 COMPLETED

Safety and Tolerability of Gefapixant (MK-7264) in Participants With Obstructive Sleep Apnea (MK-7264-039)

Merck Sharp & Dohme LLC

NCT05203419 TERMINATED

Multiple Ascending Dose Study of MHS552 in Adults Participants With Systemic Lupus Erythematosus (SLE)

Novartis Pharmaceuticals

NCT04983680 COMPLETED

Remote-delivered MBCT for SCAD Survivors

Massachusetts General Hospital

NCT05780515 COMPLETED

A Study of ANX009 in Adult Participants With Lupus Nephritis

Annexon, Inc.

NCT05349188 COMPLETED

Feasibility Study of Personalized Trials to Improve Sleep Quality

Northwell Health

NCT02618967 COMPLETED

Single Ascending Dose Study of AMG 570 in Healthy Subjects

Amgen

NCT05140824 TERMINATED

A Study to Evaluate the Safety, Tolerability, and PK Profile of Single and Multiple Doses TJ202 in Patient With Systemic Lupus Erythematosus

TJ Biopharma Co., Ltd.

NCT04809623 TERMINATED

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

Gilead Sciences

NCT03724916 COMPLETED

A Study to Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE)

Millennium Pharmaceuticals, Inc.

NCT02776215 COMPLETED

Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents

Vanda Pharmaceuticals

NCT04647708 COMPLETED

Study of M5049 in CLE and SLE Participants

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

NCT05247203 COMPLETED

Telitacicept Study in Chinese Subjects With Systemic Lupus Erythematosus

RemeGen Co., Ltd.

NCT03556007 COMPLETED

A Study of NKTR-358 (LY3471851) in Participants With Systemic Lupus Erythematosus (SLE)

Nektar Therapeutics

NCT03334851 COMPLETED

Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis

Pfizer

NCT04647383 COMPLETED

A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease

Eisai Inc.

NCT03451422 COMPLETED

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Efavaleukin Alfa in Participants With Systemic Lupus Erythematosus

Amgen

NCT05868798 COMPLETED

Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?

Jan Malecek

NCT04493541 COMPLETED

A Study to Assess the Safety and Drug Levels of BMS-986256 in Participants With Active Cutaneous Lupus Erythematosus

Bristol-Myers Squibb

NCT05008341 COMPLETED

Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration

Axsome Therapeutics, Inc.

NCT05203692 COMPLETED

A Study of a Single Ascending Dose Study of DS-7011a in Healthy Subjects

Daiichi Sankyo

NCT05458193 COMPLETED

A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep

Idorsia Pharmaceuticals Ltd.

NCT04872387 COMPLETED

A Study to Learn More About How Safe BAY2586116 is, How it Affects the Body, How it Moves Into, Through and Out of the Body at Different Doses in Healthy Japanese Male Participants After Taking Single and Multiple Doses Through the Nose

Bayer

NCT03656627 TERMINATED

Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease

Alliance Foundation Trials, LLC.

NCT05527457 COMPLETED

BAY2586116 Nasal Spray and OSA Severity

Flinders University

NCT05180890 COMPLETED

A Study of Danavorexton (TAK-925) in Adults With Obstructive Sleep Apnea

Takeda

NCT05001698 COMPLETED

Anifrolumab PK Study for Systemic Lupus Erythematosus (SLE)

AstraZeneca

NCT04618263 TERMINATED

Safety and Tolerability of Single and Multiple Ascending Doses of GATE-101 in Normal Human Volunteers

Syndeio Biosciences, Inc

NCT03618056 COMPLETED

Evaluating HIV-1 Neutralization Antibody Breadth in Response to HIV gp120 Protein Vaccine in HIV-uninfected Adults With Quiescent Systemic Lupus Erythematosus

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03771885 WITHDRAWN

BI 705564 in Patients With Systemic Lupus Erythematosus (SLE)

Boehringer Ingelheim

NCT04700267 TERMINATED

A Study Evaluating the Effects of GLPG3970 Given as Oral Treatment for 12 Weeks in Adults With Systemic Lupus Erythematosus

Galapagos NV

NCT02927457 COMPLETED

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of GSK2646264 in Cutaneous Lupus Erythematosus Subjects

GlaxoSmithKline

NCT03933943 COMPLETED

A Study of LY3361237 in Participants With Systemic Lupus Erythematosus

Eli Lilly and Company

NCT04093271 COMPLETED

Investigating the Efficacy of Rest-ZZZ Formula in Healthy Participants With Difficulty Falling Asleep or Staying a Sleep

LifeSeasons Inc.

NCT04065932 COMPLETED

A Study to Determine the Pharmacokinetic Profile of BMS-986165 Tablets

Bristol-Myers Squibb

NCT04136145 COMPLETED

Single Dose Study to Investigate the Pharmacokinetics (PK) and Safety of Belimumab 200 Milligrams (mg) Intravenous and 200 mg Subcutaneous Via Auto-injector in Chinese Healthy Subjects

GlaxoSmithKline

NCT03269760 COMPLETED

Multimodal Sleep Pathway for Shoulder Arthroplasty

University of California, San Francisco

NCT02945644 SUSPENDED

Trazodone Dose Tolerance and APAP Adherence

Louis Stokes VA Medical Center

NCT04091425 COMPLETED

Study of TAK-925 in Participants With Obstructive Sleep Apnea (OSA) Who Are Experiencing Excessive Daytime Sleepiness (EDS) Despite Adequate Use of Continuous Positive Airway Pressure (CPAP)

Millennium Pharmaceuticals, Inc.

NCT02880852 COMPLETED

Belimumab Phase I Study in Chinese Subjects With Systemic Lupus Erythematosus

GlaxoSmithKline

NCT03262727 COMPLETED

The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients

Bristol-Myers Squibb

NCT03949426 COMPLETED

Safety, Tolerability and Pharmacokinetics of KPG-818 in Healthy Subjects

Kangpu Biopharmaceuticals, Ltd.

NCT03402087 COMPLETED

A Study to Investigate BMS-986165 and Methotrexate in Healthy Male Patients

Bristol-Myers Squibb

NCT03254784 COMPLETED

A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation

Bristol-Myers Squibb

NCT03471871 COMPLETED

Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea

Eisai Inc.

NCT03541564 COMPLETED

An Investigational Study of Experimental Medication BMS-986165 in Healthy Participants to Study Electrocardiogram Effects

Bristol-Myers Squibb

NCT03765294 COMPLETED

A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep Apnea

Idorsia Pharmaceuticals Ltd.

NCT03174587 COMPLETED

Evaluate the Safety of CS20AT04 Inj. in Subjects With Lupus Nephritis

Corestemchemon, Inc.

NCT02428309 TERMINATED

Autologous Polyclonal Tregs for Lupus

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02735694 TERMINATED

Cycloserine in the Treatment of Sleep Apnea

University of Manitoba

NCT03189017 COMPLETED

A Phase I Study of ICP-022 in Healthy Subjects

Innocare Pharma Australia Pty Ltd

NCT03171194 COMPLETED

Pilot Trial of Mesenchymal Stem Cells for Systemic Lupus Erythematosus

Medical University of South Carolina

NCT02535689 COMPLETED

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT02920424 WITHDRAWN

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-56022473 in Subjects With Systemic Lupus Erythematosus

Janssen Research & Development, LLC

NCT02537028 COMPLETED

MSC2364447C Phase 1b in Systemic Lupus Erythematosus

EMD Serono Research & Development Institute, Inc.

NCT02307643 COMPLETED

Exploratory Study of MT-1303 in Systemic Lupus Erythematosus Patients

Tanabe Pharma Corporation

NCT03182413 COMPLETED

Impact of THN102 on Attention, Wakefulness and Cognitive Performance During Total Sleep Deprivation

Theranexus

NCT02829541 COMPLETED

A Phase 1, Single-Ascending-Dose, Safety, Tolerability, Pharmacokinetic(PK), and Pharmacodynamic(PD) Study of BIIB068 in Healthy Participants

Biogen

NCT02741362 TERMINATED

Safety and Efficacy of Adipose Derived Stem Cells in Refractory Rheumatoid Arthritis, Systemic Lupus Erythematosus or Sharp's Syndrome

Arkansas Heart Hospital

NCT02196285 COMPLETED

Study to Evaluate Safety and Imunogenicity of Double Viral Vaccine (MR) for Measles and Rubella

The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)

NCT02331810 WITHDRAWN

Pharmacodynamics Assessment Study After Single Subcutaneous Dose Of SAR113244 Versus Placebo In Lupus Male And Female Patients

Sanofi

NCT02483624 TERMINATED

3,3'-Diindolylmethane in Patients With Systemic Lupus Erythematosus

Northwell Health

NCT06594068 RECRUITING

Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users

AstraZeneca

NCT07087912 NOT YET RECRUITING

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

University of Sao Paulo General Hospital

NCT06784479 ACTIVE NOT RECRUITING

Combination of Remimazolam and Propofol During Drug-induced Sleep Endoscopy

Dan Liu

NCT06875960 RECRUITING

A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132

Bristol-Myers Squibb

NCT07407400 NOT YET RECRUITING

Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients

Mahidol University

NCT07323524 NOT YET RECRUITING

Dapagliflozin in Active Lupus Nephritis

Brigham and Women's Hospital

NCT07381465 NOT YET RECRUITING

Efficacy and Safety of IL-1 Inhibitors in Mild to Moderate Systemic Lupus Erythematosus

Chinese SLE Treatment And Research Group

NCT07077486 RECRUITING

Effects of Telitacicept vs Cyclophosphamide on Lupus Related Interstitial Lung Disease

Tongji Hospital

NCT06480539 RECRUITING

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

Ziekenhuis Oost-Limburg

NCT06132477 RECRUITING

Impact GLP-1 Agonists Following Bariatric

University of Missouri-Columbia

NCT07328594 NOT YET RECRUITING

Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking

Legacy Health System

NCT04991389 RECRUITING

Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

Children's Hospital Medical Center, Cincinnati

NCT05209035 ACTIVE NOT RECRUITING

Evaluation of Trazodone in OSA-MCI

Chinese University of Hong Kong

NCT05559671 RECRUITING

Safety of the Herpes Zoster Subunit Vaccine in Lupus

NYU Langone Health

NCT07280468 NOT YET RECRUITING

Endotype DIrected Treatment for OSA in Down Syndrome

University of Arizona

NCT07228195 NOT YET RECRUITING

SGLT2i Therapy in Islet Transplantation (SIT)

University of Minnesota

NCT06576830 RECRUITING

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

Duke University

NCT05879419 ACTIVE NOT RECRUITING

Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases

University of Sao Paulo General Hospital

NCT06411249 RECRUITING

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

GlaxoSmithKline

NCT02922894 RECRUITING

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

John D. Dingell VA Medical Center

NCT07225387 RECRUITING

Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial

NephroNet, Inc.

NCT02703220 RECRUITING

Sleep Apnea in Elderly

VA Office of Research and Development

NCT06089603 RECRUITING

CPAP Effect on the Polycythemia in Patients With Obstructive Sleep Apnea

Hospital Universitario Ramon y Cajal

NCT05612594 RECRUITING

Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study

Yale University

NCT05950646 RECRUITING

Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality

Peking University First Hospital

NCT04220671 ENROLLING BY INVITATION

Measles Vaccination at Health System Contacts

Bandim Health Project

NCT03642028 RECRUITING

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

VA Office of Research and Development

NCT05514106 ENROLLING BY INVITATION

MIBG in Aging and Neurologic Disorders

Mayo Clinic

NCT07035834 NOT YET RECRUITING

SGLT-2 Inhibitors on Albuminuria in Chronic Kidney Disease Patients With Lupus Nephritis and ANCA- Associated Vasculitis

Federico II University

NCT06498531 RECRUITING

HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men

University of Zurich

NCT06902285 RECRUITING

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

University of Miami

NCT06874855 RECRUITING

Lemborexant in Delayed Sleep Phase Syndrome

University of California, San Francisco

NCT06859892 RECRUITING

Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery

Peking University First Hospital

NCT06778811 RECRUITING

Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery

Nanjing First Hospital, Nanjing Medical University

NCT02630121 RECRUITING

Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

University of South Florida

NCT06763783 ENROLLING BY INVITATION

Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases

Region Skane

NCT06710574 RECRUITING

Multimodal Image Technologies Investigate the Role and Mechanism of Probiotics in Improving RBD with Parkinson's Disease

Beijing Friendship Hospital

NCT06684444 ENROLLING BY INVITATION

Evaluating Worksite Sleep Health Coaching in Firefighters: The Sleep Assistance for Firefighters Study

University of Arizona

NCT06677801 ACTIVE NOT RECRUITING

Immune Cell Subsets in SLE Patients Treated with Telitacicept

Second Affiliated Hospital, School of Medicine, Zhejiang University

NCT05042258 RECRUITING

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Northwestern University

NCT06566482 RECRUITING

Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA

Peking University First Hospital

NCT06463561 RECRUITING

CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea

Hospital Universitario La Paz

NCT05916781 RECRUITING

Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus

Chinese SLE Treatment And Research Group

NCT04227093 ACTIVE NOT RECRUITING

Acetazolamide Add-On Therapy to OSA Surgery

University Hospital, Antwerp

NCT05846490 RECRUITING

Impact of Obstructive Sleep Apnea (OSA) Treatment on Blood Pressure Control in Chronic Kidney Disease

University of Sao Paulo

NCT06380491 RECRUITING

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

NCT05924425 RECRUITING

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

University Hospital, Montpellier

NCT06017921 RECRUITING

Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA

University of Sao Paulo General Hospital

NCT03543839 RECRUITING

Trial of Belimumab in Early Lupus

Northwell Health

NCT05828147 RECRUITING

Anti-CD20 Antibodies for Treatment of SLE-PAH

Chinese SLE Treatment And Research Group

NCT04899765 RECRUITING

Measles and BCG Vaccines for Mother and Child

Bandim Health Project

NCT06009289 NOT YET RECRUITING

Light and Sleep Fragmentation

Stanford University

NCT05207358 RECRUITING

Minimizing Glucocorticoid Administration in Patients With Proliferative Lupus Nephritis

Institutul Clinic Fundeni

NCT04627480 ACTIVE NOT RECRUITING

Evaluation of a Neurostimulation Device for Insomnia: A Randomized Trial

ProofPilot

NCT04192656 RECRUITING

The Effect of PAP on ISSHL Comorbided With OSA

Beijing Tsinghua Chang Gung Hospital

NCT05463861 COMPLETED

Lemborexant in Delayed Sleep Phase Syndrome

Stanford University

NCT05344443 COMPLETED

Lemborexant Shift Work Treatment Study

University of California, San Francisco

NCT04789174 COMPLETED

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study

Axsome Therapeutics, Inc.

NCT05718024 COMPLETED

Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients

Peking University First Hospital

NCT06295562 COMPLETED

Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea

China Medical University Hospital

NCT04092894 COMPLETED

Suvorexant and Sleep/Delirium in ICU Patients

Beth Israel Deaconess Medical Center

NCT05382494 COMPLETED

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children

Murdoch Childrens Research Institute

NCT04726982 COMPLETED

Optimal Dosage of Acetazolamide for OSA Treatment

University Hospital, Antwerp

NCT04788953 TERMINATED

Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder

Charles A. Czeisler, PhD, MD

NCT06331702 COMPLETED

Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR)

Liaoning Chengda Biotechnology CO., LTD

NCT05732064 COMPLETED

Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality

Peking University First Hospital

NCT04263363 COMPLETED

Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications

University of California, Los Angeles

NCT04908865 COMPLETED

Open-label Study of Belimumab Plus Standard Therapy in Chinese Pediatric Participants With Active Systemic Lupus Erythematosus (SLE)

GlaxoSmithKline

NCT03071575 COMPLETED

Measles-Rubella Vaccine Immunogenicity at 6 and 9 Months of Age

Centers for Disease Control and Prevention

NCT03031626 COMPLETED

Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome

The Hospital for Sick Children

NCT04515719 COMPLETED

Efficacy and Safety of Belimumab in SLE Patients

RenJi Hospital

NCT06898463 COMPLETED

Comparison Of The Effects Of Melatonin Premedication And Ketamine On Postoperative Sleep Quality İn Rhinoplasty

Konya City Hospital

NCT05748925 COMPLETED

Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients

Mansoura University

NCT03679611 COMPLETED

Impact of Sugammadex vs. Neostigmine Reversal on Post-Operative Recovery and Complications

University Health Network, Toronto

NCT05393531 COMPLETED

First Line Obstructive Sleep Apnea Treatment Study

University Hospital, Antwerp

NCT05074056 COMPLETED

Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectomy

St. Louis University

NCT05704088 COMPLETED

SGLT2 Inhibitors Between Reno Protective Effects and Impact on Bone and Mineral Disease Among Lupus Nephritis Patients

Mansoura University

NCT03467750 COMPLETED

Effect of Ketorolac on Post Adenotonsillectomy Pain

Emory University

NCT03945955 COMPLETED

Melatonin and DNA Damage Study

University of British Columbia

NCT03011294 COMPLETED

Cardiovascular Impact, Quality e Quantity of Sleep in Bed Partners of Patients With Obstructive Sleep Apnea

University of Sao Paulo

NCT03936751 TERMINATED

Obstructive Sleep Apnea Treatment on Cardiovascular Events in Patients With Acute Cardiogenic Pulmonary Edema: CPAP-CARE STUDY.

University of Sao Paulo

NCT03111485 COMPLETED

Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease

McGill University Health Centre/Research Institute of the McGill University Health Centre

NCT03435003 COMPLETED

Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy

Stony Brook University

NCT04720547 COMPLETED

Sleep and Breathing in the General Population - Chemical Stimuli

Wayne State University

NCT04006925 COMPLETED

Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate

Stanford University

NCT05037032 COMPLETED

Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude

VA Loma Linda Health Care System

NCT03762824 COMPLETED

Combined Pneumococcal Conjugate and Polysaccharide Vaccination in Inflammatory Rheumatic Disease

Region Skane

NCT04188106 COMPLETED

Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment

Rose Research Center, LLC

NCT04329091 TERMINATED

Implications of Anesthetics on Sleep Consolidation

University of Chicago

NCT04608331 COMPLETED

Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep Apnea

Peking University First Hospital

NCT03856788 COMPLETED

Unilateral TAP Block for Laparoscopic Gastric Sleeve Surgery

Icahn School of Medicine at Mount Sinai

NCT04120363 COMPLETED

Trial of Testosterone Undecanoate for Optimizing Performance During Military Operations

Pennington Biomedical Research Center

NCT04956484 COMPLETED

Belimumab In Early Systemic Lupus Erythematosus

Peking Union Medical College Hospital

NCT04424602 COMPLETED

Comparison between2 Drugs in Lupus Nephritis

Al-Azhar University

NCT04205136 WITHDRAWN

Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients

University of Michigan

NCT05250245 COMPLETED

Tolterodine Relieves Overactive Bladder Symptoms in Women With Moderate-to-severe Obstructive Sleep Apnea Syndrome

Yuzuncu Yil University

NCT04479566 COMPLETED

Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery

China Medical University, China

NCT03122431 COMPLETED

Relevance of Monitoring Blood and Salivar Levels of Drugs Used in Rheumatic Autoimmune Diseases

University of Sao Paulo General Hospital

NCT02807922 COMPLETED

Pharmacological Treatment of Insomnia in Palliative Care

St. Olavs Hospital

NCT02916160 COMPLETED

Sacubitril-valsartan and Heart Failure Patients : the ENTRESTO-SAS Study

University Hospital, Montpellier

NCT02820441 TERMINATED

Benefit of One Month Zopiclone Intake on Adaptative Servoventilation Compliance

University Hospital, Grenoble

NCT02874313 COMPLETED

CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea

Hospital Universitario La Paz

NCT02816762 COMPLETED

CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea

Hospital Universitario La Paz

NCT03117790 COMPLETED

Impact of Dexmedetomidine on Sleep Quality

Peking University First Hospital

NCT03859570 WITHDRAWN

Pentoxifylline in Lupus Nephritis

MetroHealth Medical Center

NCT03920059 TERMINATED

Fixed-dose Versus Concentration-controlled Mycophenolate Mofetil for the Treatment of Active Lupus Nephritis

Chulalongkorn University

NCT03454217 COMPLETED

Impact of Tramadol and Oxycodone on Sleep Apnea

Centre Hospitalier Universitaire Vaudois

NCT02699125 COMPLETED

Treatment of OSA Associated Hypertension With Alpha 2 Agonist or Diuretic

University of California, San Diego

NCT02880865 COMPLETED

Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella (MMR) Vaccine

PATH

NCT02953821 COMPLETED

Acthar Gel for Active Systemic Lupus Erythematosus (SLE)

Mallinckrodt

NCT03098823 COMPLETED

A Crossover Study to Compare RAYOS to IR Prednisone to Improve Fatigue and Morning Symptoms for SLE

Ampel BioSolutions, LLC

NCT02295202 COMPLETED

Impact of Obstructive Sleep Apnea Treatment in Patients With Metabolic Syndrome

University of Sao Paulo

NCT02714400 COMPLETED

The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea

University of California, San Diego

NCT02162433 TERMINATED

The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation

Massachusetts Eye and Ear Infirmary

NCT04162743 COMPLETED

The Effect of Trazodone on the Severity of Obstructive Sleep Apnea in Insomnic Stroke Patients With Depression

Chang Gung Memorial Hospital

NCT03307005 COMPLETED

Improving Sleep Quality in Heart Failure

Johns Hopkins University

NCT02643979 TERMINATED

Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy

Icahn School of Medicine at Mount Sinai

NCT03522207 TERMINATED

Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient

Centre hospitalier de l'Université de Montréal (CHUM)

NCT02566226 COMPLETED

Impact of Intrathecal Morphine on Sleep Apnea Syndrome

Centre Hospitalier Universitaire Vaudois

NCT04146220 COMPLETED

Efficacy of Lower Dose Prednisolone in the Induction of Remission of Lupus Nephritis

Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

NCT02741960 COMPLETED

The Effect of Metformin on Reducing Lupus Flares

RenJi Hospital

NCT02779153 WITHDRAWN

Acthar SLE (Systemic Lupus Erythematosus)

NYU Langone Health

NCT02477150 COMPLETED

Safety and Immunogenicity of a Zoster Vaccine in SLE

Tuen Mun Hospital

NCT02494102 TERMINATED

Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea

Milton S. Hershey Medical Center

NCT03540823 COMPLETED

Evaluation of Influenza A/H3N2 Vaccine in Patients With Rheumatologic Diseases

University of Sao Paulo General Hospital

NCT02717780 COMPLETED

Short Life Agents in Balanced Anesthesia on Obstructive Sleep Apnea Syndrome

Centre Hospitalier Universitaire Vaudois

NCT02042001 COMPLETED

Switching From Efavirenz/Atripla to Rilpivirine Among Patients With Neurocognitive or Neuropsychological Side Effects

Azienda Ospedaliera San Gerardo di Monza

NCT02325310 COMPLETED

Search for the Measles Vaccine Virus Excretion in Breast Milk of Breastfeeding Women After Postpartum Vaccination With MMR

Assistance Publique - Hôpitaux de Paris

NCT02426424 WITHDRAWN

Effect Of Early C-PAP Treatment For Sleep Apnea On Rehabilitation Of Stroke Patients

Soroka University Medical Center

NCT03091894 COMPLETED

Dexmedetomidine Added to Propofol for Drug Induced Sleep Endoscopy

Essam Fathi

NCT02234362 COMPLETED

Vortioxetine for Menopausal Depression

Massachusetts General Hospital

NCT03160820 COMPLETED

Study on Immunization Schedule of Beijing Tiantan Biological's Measles-mumps-rubella(MMR) Vaccine

Centers for Disease Control and Prevention, China

NCT02651519 COMPLETED

Sleep Quality After Stellate-ganglion Block of Patients Undergoing Breast Cancer Operation

China Medical University, China

NCT02645565 COMPLETED

Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis

Jawaharlal Institute of Postgraduate Medical Education & Research

NCT02675816 TERMINATED

Inspire® Upper Airway Stimulation System

Inspire Medical Systems, Inc.

NCT02643433 COMPLETED

Immunogenicity of Co-administration of Measles and Japanese Encephalitis Vaccines

Centers for Disease Control and Prevention, China

NCT02599701 TERMINATED

Acute Effects of Gabapentin in Sleep Parameters and Hormonal Release During Sleep in Older Men

Associação Fundo de Incentivo à Pesquisa

NCT02529514 SUSPENDED

Usage of Baclofen for Sleep Improvement After Cardiac Surgery

University of Liege

Data: ClinicalTrials.gov