NCT02675829 ACTIVE NOT RECRUITING Trial of Ado-Trastuzumab Emtansine for Patients With HER2 Amplified or Mutant Cancers
Memorial Sloan Kettering Cancer Center
NCT05198830 RECRUITING Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
NCT02465060 ACTIVE NOT RECRUITING Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
National Cancer Institute (NCI)
NCT07450183 NOT YET RECRUITING Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1
Henry Ford Health System
NCT05068232 RECRUITING Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)
University of Chicago
NCT07169617 NOT YET RECRUITING Testing the SurVaxM Vaccine for Lung Cancer Prevention
National Cancer Institute (NCI)
NCT07012031 RECRUITING Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation
National Cancer Institute (NCI)
NCT06287775 RECRUITING Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
National Cancer Institute (NCI)
NCT04310020 ACTIVE NOT RECRUITING Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
National Cancer Institute (NCI)
NCT04716946 ACTIVE NOT RECRUITING Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapy
Memorial Sloan Kettering Cancer Center
NCT03057106 ACTIVE NOT RECRUITING Durvalumab and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous NSCLC
Canadian Cancer Trials Group
NCT06747585 RECRUITING A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors
Alentis Therapeutics AG
NCT07447050 RECRUITING Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
University of California, Irvine
NCT04771520 RECRUITING Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
M.D. Anderson Cancer Center
NCT03598309 ACTIVE NOT RECRUITING Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers
H. Lee Moffitt Cancer Center and Research Institute
NCT04485286 RECRUITING Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury
Massachusetts General Hospital
NCT05280470 ACTIVE NOT RECRUITING Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
Daiichi Sankyo
NCT03737994 ACTIVE NOT RECRUITING Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT04895709 RECRUITING A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT07433283 RECRUITING Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor
Sichuan Enray Pharmaceutical Sciences Company
NCT04471727 ACTIVE NOT RECRUITING A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT06618287 RECRUITING A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT06918132 RECRUITING Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer
Mayo Clinic
NCT05969860 RECRUITING At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Mayo Clinic
NCT07038343 RECRUITING AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Avenzo Therapeutics, Inc.
NCT06051695 RECRUITING A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
A2 Biotherapeutics Inc.
NCT07104630 RECRUITING Pulmonary Rehabilitation in Advanced Lung Cancer Survivors
Case Comprehensive Cancer Center
NCT06038526 ACTIVE NOT RECRUITING Evaluation of Canakinumab in High-Risk Former-Smokers
Peter Shields
NCT04892953 RECRUITING Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy
M.D. Anderson Cancer Center
NCT07410676 RECRUITING EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Essen Biotech
NCT06943664 NOT YET RECRUITING Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer
Roswell Park Cancer Institute
NCT07145255 RECRUITING Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
MBrace Therapeutics
NCT05633667 RECRUITING Study of Novel Treatment Combinations in Patients With Lung Cancer
Gilead Sciences
NCT07379476 RECRUITING Local Ablative Therapy to Oligoresidual Metastasis in EGFR Mutated Non-small Cell Lung Cancer
Chinese University of Hong Kong
NCT07405190 NOT YET RECRUITING Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLC
Massachusetts General Hospital
NCT07405086 NOT YET RECRUITING Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study
OHSU Knight Cancer Institute
NCT03830918 ACTIVE NOT RECRUITING Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy
Jonsson Comprehensive Cancer Center
NCT06731270 RECRUITING Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy
Emory University
NCT06892548 RECRUITING A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
BioNTech SE
NCT05419076 RECRUITING A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Memorial Sloan Kettering Cancer Center
NCT03582124 RECRUITING Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery
Stanford University
NCT04585750 RECRUITING The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
PMV Pharmaceuticals, Inc
NCT06878274 RECRUITING Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC
Centre hospitalier de l'Université de Montréal (CHUM)
NCT03896074 ACTIVE NOT RECRUITING Atezolizumab Versus Atezolizumab Plus Bevacizumab as First Line in NSCLC Patients (BEAT)
Fondazione Ricerca Traslazionale
NCT07393555 NOT YET RECRUITING Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial)
SWOG Cancer Research Network
NCT07230405 RECRUITING A Phase II Study of SKB571 in Patients With Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT06582771 RECRUITING A Study of Sotorasib in People With Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center
NCT03141359 ACTIVE NOT RECRUITING Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC
Wake Forest University Health Sciences
NCT04223596 ACTIVE NOT RECRUITING Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients
Fundación GECP
NCT02525757 ACTIVE NOT RECRUITING MPDL3280A With Chemoradiation for Lung Cancer
M.D. Anderson Cancer Center
NCT07242547 RECRUITING Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients
Fundación GECP
NCT05616624 ACTIVE NOT RECRUITING ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers
Washington University School of Medicine
NCT06405230 RECRUITING Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Extracellular Vesicles (EVs), Patient-derived Organoid (PDOs)s and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)
GlaxoSmithKline
NCT06810544 RECRUITING Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
Tango Therapeutics, Inc.
NCT04340882 ACTIVE NOT RECRUITING Phase 2 DoceRamPem for Patients With Metastatic or Recurrent NSCLC Who Progressed on Platinum-Doublet and PD-1/PD-L1 Blockade
Emory University
NCT05340309 ACTIVE NOT RECRUITING Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung Cancer
University of Southern California
NCT06172478 RECRUITING A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Daiichi Sankyo
NCT06926075 RECRUITING Early Phase Study of Kesonotide in Participants With Solid Tumours
Filamon LTD
NCT06810609 RECRUITING Immunochemotherapy, Surgery or Chemoradiation, and Durvalumab for Stage IIIA/B NSCLC
University Hospital, Bonn
NCT04958811 ACTIVE NOT RECRUITING Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced Non-squamous NSCLC
Georgetown University
NCT07367529 NOT YET RECRUITING A Clinical Trial on the Efficacy and Safety of TQB6411 for Injection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT07174583 RECRUITING A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer
IDEAYA Biosciences
NCT06031688 RECRUITING Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
SWOG Cancer Research Network
NCT05849129 RECRUITING Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung Cancer
The Canadian College of Naturopathic Medicine
NCT03377023 ACTIVE NOT RECRUITING Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT04748419 ACTIVE NOT RECRUITING Safety & Efficacy of Consolidative Hypofractionated Radiation Therapy for Boosting Residual Lung Cancer With Durvalumab
University of Nebraska
NCT05374603 ACTIVE NOT RECRUITING Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC
AstraZeneca
NCT05705492 RECRUITING Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
OHSU Knight Cancer Institute
NCT07354919 NOT YET RECRUITING Axelopran in Advanced Cancers
HealthPartners Institute
NCT07354711 RECRUITING A First-in-human Study of 3H-10000 in Patients With Unresectable or Metastatic Solid Tumors
3H Pharmaceuticals Co., Ltd.
NCT07353957 RECRUITING Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer
Merus B.V.
NCT03225664 ACTIVE NOT RECRUITING Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced
M.D. Anderson Cancer Center
NCT07341737 NOT YET RECRUITING SL-28 for Advanced Solid Tumours
Second Life Therapeutics
NCT05845671 ACTIVE NOT RECRUITING Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET Alterations
University of Colorado, Denver
NCT07336732 NOT YET RECRUITING Andamertinib as First-line Treatment for NSCLC With EGFR PACC or EGFR L861Q Mutation
Avistone Biotechnology Co., Ltd.
NCT07103395 RECRUITING A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer
Sun Yat-sen University
NCT05565378 ACTIVE NOT RECRUITING A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer
GlaxoSmithKline
NCT07322341 NOT YET RECRUITING SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer
University of Washington
NCT04691817 RECRUITING Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy
Abramson Cancer Center at Penn Medicine
NCT06877299 RECRUITING Low-Dose Radiation + SBRT + Tislelizumab Plus Platinum-based Chemotherapy in Stage ⅡA-ⅢB Non-small Cell Lung Cancer
Sichuan University
NCT04367311 ACTIVE NOT RECRUITING Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)
Nasser Hanna
NCT07309276 NOT YET RECRUITING A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer
Shanghai Junshi Bioscience Co., Ltd.
NCT07307443 NOT YET RECRUITING A Phase II Study of Anlotinib and Platinum-Based Chemotherapy in Patients With SMARCA4-Deficient, Locally Advanced or Metastatic Lung Cancer.
Zhijie Wang
NCT07308106 NOT YET RECRUITING A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With MET Abnormalities
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT04789681 RECRUITING Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial
M.D. Anderson Cancer Center
NCT02905591 ACTIVE NOT RECRUITING A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC
Joseph J. Cullen, MD, FACS
NCT07303881 NOT YET RECRUITING Golidocitinib for Refractory Immune-related Hematologic Toxicities of Advanced Lung Cancer
The First Affiliated Hospital of Guangzhou Medical University
NCT03410043 ACTIVE NOT RECRUITING Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study
M.D. Anderson Cancer Center
NCT05305365 ACTIVE NOT RECRUITING Study Assessing QBS72S For Treating Brain Metastases
Stanford University
NCT05975073 ACTIVE NOT RECRUITING A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors
Amgen
NCT05632809 RECRUITING REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)
M.D. Anderson Cancer Center
NCT07295821 NOT YET RECRUITING Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study
AstraZeneca
NCT03634241 ACTIVE NOT RECRUITING Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study
M.D. Anderson Cancer Center
NCT07285044 RECRUITING The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Mayo Clinic
NCT07155200 RECRUITING Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)
Washington University School of Medicine
NCT04940299 ACTIVE NOT RECRUITING Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma
M.D. Anderson Cancer Center
NCT02638090 ACTIVE NOT RECRUITING Pembro and Vorinostat for Patients With Stage IV Non-small Cell Lung Cancer (NSCLC)
H. Lee Moffitt Cancer Center and Research Institute
NCT07017829 RECRUITING GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer
Roswell Park Cancer Institute
NCT07169734 RECRUITING A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Alentis Therapeutics AG
NCT03728361 ACTIVE NOT RECRUITING Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer
Dwight Owen
NCT04728230 ACTIVE NOT RECRUITING Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial
M.D. Anderson Cancer Center
NCT02971501 ACTIVE NOT RECRUITING Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases
National Cancer Institute (NCI)
NCT06293690 ACTIVE NOT RECRUITING Toripalimab Combined With SBRT for NSCLC
Shanghai Pulmonary Hospital, Shanghai, China
NCT02955940 ACTIVE NOT RECRUITING An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
Incyte Corporation
NCT07288034 NOT YET RECRUITING Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial
City of Hope Medical Center
NCT05450965 RECRUITING Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer
University of Maryland, Baltimore
NCT07285148 NOT YET RECRUITING A Study to Evaluate ANS014004 in Combination With EGFR-TKI in Non-Small Cell Lung Cancer
Beijing Pearl Biotechnology Limited Liability Company
NCT04736173 ACTIVE NOT RECRUITING Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer
Arcus Biosciences, Inc.
NCT04701307 ACTIVE NOT RECRUITING Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas
M.D. Anderson Cancer Center
NCT07232849 RECRUITING A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT03556228 RECRUITING VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
VM Oncology, LLC
NCT06922591 RECRUITING Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
Tango Therapeutics, Inc.
NCT06518057 RECRUITING Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
University of Washington
NCT04745689 ACTIVE NOT RECRUITING Study of AZD2811 + Durvalumab in ES-SCLC
AstraZeneca
NCT05256290 ACTIVE NOT RECRUITING Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations
Black Diamond Therapeutics, Inc.
NCT07019675 RECRUITING A Study of SKB518 in Patients With Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT05886439 RECRUITING LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06910761 RECRUITING Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer
City of Hope Medical Center
NCT04625647 ACTIVE NOT RECRUITING Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
SWOG Cancer Research Network
NCT06449209 ACTIVE NOT RECRUITING Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy
BioNTech SE
NCT05642572 RECRUITING Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
SWOG Cancer Research Network
NCT06194448 ACTIVE NOT RECRUITING To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations
AstraZeneca
NCT05986318 RECRUITING Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
David Palma
NCT05570825 RECRUITING SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer
University of Washington
NCT07261098 NOT YET RECRUITING The Efficacy and Safety of ARNI on the Outcome of Advanced Lung Cancer With Concurrent Hypertension
Shanghai Chest Hospital
NCT04010357 ACTIVE NOT RECRUITING Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC
Case Comprehensive Cancer Center
NCT07258147 NOT YET RECRUITING Safety and Efficacy of Radiotherapy Combined With Immunochemotherapy in Pre-treated SCLC Patients With Liver Metastases
Sichuan University
NCT07260058 NOT YET RECRUITING Immune Cell Therapy for Advanced Solid Tumors
Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd.
NCT05568212 RECRUITING Randomized Trial Comparing Standard of Care Versus Immune- Based Combination in Relapsed Stage III Non-small-cell Lung Cancer (NSCLC) Pretreated With Chemoradiotherapy and Durvalumab
Fondazione Ricerca Traslazionale
NCT03999710 ACTIVE NOT RECRUITING Determining Whether Durvalumab in Combination With Radiation Therapy Can Prevent the Progression of Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center
NCT04940325 ACTIVE NOT RECRUITING Datopotamab Deruxtecan (Dato-DXd, DS-1062a) in Advanced and/or Unresectable Non-Small Cell Lung Cancer
Gustave Roussy, Cancer Campus, Grand Paris
NCT07016230 RECRUITING Study Investigating Tarlatamab (AMG 757) in Patients With Metastatic/Locally Advanced Small-Cell Lung Cancer (SCLC) and Other Poorly Differentiated Neuroendocrine Carcinomas (NECs), With Biomarker Analysis to Characterize Response/Resistance (UNLOCK TARLATAMAB)
Gustave Roussy, Cancer Campus, Grand Paris
NCT04995523 RECRUITING A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC
AstraZeneca
NCT07244926 NOT YET RECRUITING Sac-TMT Plus Bevacizumab as Second-Line Treatment for Advanced Non-Squamous Non-Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT07241767 RECRUITING A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT05786924 RECRUITING Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Institut de Recherches Internationales Servier
NCT05017025 ACTIVE NOT RECRUITING Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT06455917 RECRUITING TIL Therapy in Non-small-cell Lung Cancer (NSCLC) Patients
University Hospital, Basel, Switzerland
NCT07153445 RECRUITING Neoadjuvant Treatment With Atezolizumab and Atezolizumab as Maintenance for the Treatment of Stage III Non Small-Cell Lung Cancer (NSCLC)
Fundación GECP
NCT05887492 RECRUITING Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
Tango Therapeutics, Inc.
NCT07229599 RECRUITING A Study of MHB036C Combined With Anti-tumor Therapies in Patients With Advanced Lung Cancer
Minghui Pharmaceutical (Hangzhou) Ltd
NCT04310007 ACTIVE NOT RECRUITING Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT05588388 RECRUITING Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases
Kamya Sankar
NCT02955290 ACTIVE NOT RECRUITING CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer
Roswell Park Cancer Institute
NCT05902988 RECRUITING A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Volastra Therapeutics, Inc.
NCT03110978 ACTIVE NOT RECRUITING Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT04919382 RECRUITING Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer
Dwight Owen
NCT05607108 RECRUITING A Study of ZEN003694 in People With Squamous Cell Lung Cancer
Memorial Sloan Kettering Cancer Center
NCT06228326 RECRUITING A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
Krystal Biotech, Inc.
NCT05987644 RECRUITING Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
Joshua Palmer
NCT04991025 RECRUITING Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery
Memorial Sloan Kettering Cancer Center
NCT05118854 RECRUITING A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation
M.D. Anderson Cancer Center
NCT06644768 RECRUITING A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
Daiichi Sankyo
NCT02414269 ACTIVE NOT RECRUITING Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Memorial Sloan Kettering Cancer Center
NCT03600701 ACTIVE NOT RECRUITING Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT04931017 ACTIVE NOT RECRUITING Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer
Northwestern University
NCT07207395 RECRUITING A Study of Orally Administered JBI-802 Alone or in Combination With Pembrolizumab for Patients With Non-small Cell Lung Cancer With an STK11 Mutation.
The Christ Hospital
NCT03693014 ACTIVE NOT RECRUITING A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors
Memorial Sloan Kettering Cancer Center
NCT07202611 RECRUITING DC/NK Cell Therapy
National Taiwan University Clinical Trial Center
NCT04472949 ACTIVE NOT RECRUITING Thoracic Radiotherapy Plus Maintenance Durvalumab After First Line Carboplatin and Etoposide Plus Durvalumab in Extensive-stage Disease Small Cell Lung Cancer (ED-SCLC).
Swiss Cancer Institute
NCT07200154 NOT YET RECRUITING Adebrelimab Plus Chemoradiotherapy Followed by Adebrelimab Maintenance in Limited-Stage SCLC
Peking University Cancer Hospital & Institute
NCT07198841 NOT YET RECRUITING IBI351 Plus Cetuximab β in Untreated Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation
Guangdong Association of Clinical Trials
NCT06822543 RECRUITING A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)
Latin American Cooperative Oncology Group
NCT07197008 NOT YET RECRUITING Sacituzumab Tirumotecan (Sac-TMT) Plus Bevacizumab in 3rd Generation EGFR-TKI Treated Advanced EGFR-mutant Nonsquamous NSCLC With Brain Metastasis
Li-kun Chen
NCT06463665 RECRUITING Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer
Genelux Corporation
NCT06448910 ACTIVE NOT RECRUITING Cadonilimab(AK104) Plus Concurrent Chemoradiotherapy in Patients With Locally Advanced, Unresectable, Stage III NSCLC
Fudan University
NCT03965689 ACTIVE NOT RECRUITING Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy
National Cancer Institute (NCI)
NCT04273061 RECRUITING Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
British Columbia Cancer Agency
NCT03831932 ACTIVE NOT RECRUITING Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT07064876 NOT YET RECRUITING Serplulimab Combined With Cryoablation for Early-Stage Non-Small Cell Lung Cancer
Xi Junjie
NCT04105270 RECRUITING RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial
Masonic Cancer Center, University of Minnesota
NCT06682793 RECRUITING A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A2 Biotherapeutics Inc.
NCT04516070 ACTIVE NOT RECRUITING Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis
M.D. Anderson Cancer Center
NCT04067830 RECRUITING Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
Roswell Park Cancer Institute
NCT06784791 RECRUITING Preoperative Amivantamab or Amivantamab and Carboplatin/Pemetrexed Treatment in Patients With Resectable Non-small-cell Lung Cancer Harboring Oncogenic EGFR Mutations (NEOpredict-EGFR)
University Hospital, Essen
NCT06060613 RECRUITING Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Obsidian Therapeutics, Inc.
NCT05796089 ACTIVE NOT RECRUITING Chemotherapy and Immunotherapy in Extensive-Stage Small-Cell Lung Cancer With Thoracic Radiotherapy
Trans Tasman Radiation Oncology Group
NCT07139041 NOT YET RECRUITING Iparomlimab and Tuvonralimab Plus Chemotherapy for Inducing Conversion to Resectability in Initially Unresectable Stage III NSCLC
Chang Chen
NCT05242965 ACTIVE NOT RECRUITING A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer
University of Washington
NCT05609578 RECRUITING Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation
Mirati Therapeutics Inc.
NCT07120282 NOT YET RECRUITING Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLC
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT07103408 NOT YET RECRUITING A Study Evaluating Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade for Limited-stage Small Cell Lung Cancer
Sun Yat-sen University
NCT07101627 NOT YET RECRUITING A Prospective, Multicenter Clinical Study of Hetrombopag in the Prevention of Thrombocytopenia Caused by Lung Cancer Therapy
Shanghai Pulmonary Hospital, Shanghai, China
NCT05318027 RECRUITING ChatBot and Activity Monitoring in Patients Undergoing Chemoradiotherapy
Abramson Cancer Center at Penn Medicine
NCT07092137 NOT YET RECRUITING Nano-crystalline Megestrol Acetate for Anorexia-Cachexia Syndrome in Advanced Lung Cancer
Guangzhou Institute of Respiratory Disease
NCT07083687 NOT YET RECRUITING Lorlatinib in ROS1+ NSCLC With Brain Metastasis
Hunan Cancer Hospital
NCT07076914 NOT YET RECRUITING Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
NCT07058948 RECRUITING Spatially Fractionated Radiotherapy Combined With Immunotherapy for Advanced Solid Tumors
Tianjin Medical University Cancer Institute and Hospital
NCT07061535 NOT YET RECRUITING Sintilimab Combined With Tafolecimab and Chemotherapy as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04268550 ACTIVE NOT RECRUITING Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial)
SWOG Cancer Research Network
NCT06227546 ACTIVE NOT RECRUITING MGC018 in Patients With Relapsed or Refractory Extensive-Stage Small-Cell Lung Cancer
Georgetown University
NCT05578326 RECRUITING Study of Trilaciclib and Lurbinectidin
UNC Lineberger Comprehensive Cancer Center
NCT05919147 ACTIVE NOT RECRUITING The Neuroendocrine Effects of Pioglitazone in Patients With Cancer and Cachexia
Pennington Biomedical Research Center
NCT04181788 ACTIVE NOT RECRUITING Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies
Pfizer
NCT03175224 RECRUITING APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Apollomics Inc.
NCT04285671 ACTIVE NOT RECRUITING Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer
Jonsson Comprehensive Cancer Center
NCT06580002 RECRUITING Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
University of California, Irvine
NCT04591002 RECRUITING Osimertinib to Suppress the Progression of GGN(EGFR Mutation-positive)
Samsung Medical Center
NCT06987734 RECRUITING Neoadjuvant Sugemalimab + Chemotherapy Followed by Adjuvant Sugemalimab for Patients With Resectable Stage II-IIIA Non-small-cell Lung Cancer Patients
Shanghai Pulmonary Hospital, Shanghai, China
NCT06713798 NOT YET RECRUITING Targeting PD-L1 and TIGIT in Tumors With Tertiary Lymphoid Structures
Gustave Roussy, Cancer Campus, Grand Paris
NCT04699188 ACTIVE NOT RECRUITING Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
Novartis Pharmaceuticals
NCT06775678 RECRUITING Spatial Fragmentation Combined With Low-dose Radiotherapy for Immunotherapy Combined With Chemotherapy-resistant Locally Advanced or Advanced Non-small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT04533451 ACTIVE NOT RECRUITING Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer
Alliance for Clinical Trials in Oncology
NCT06924398 RECRUITING Postoperative EGFR-TKI Therapy forContralateral Pulmonary Nodules in Patients With EGFR-Mutant NSCLC(ARMOR2501)
Sun Yat-sen University
NCT07009925 NOT YET RECRUITING Phase II Study of Platinum (Cisplatin/Carboplatin)and Polymeric Micelles Paclitaxel(Pm-Pac) With Ivonescimab in First Line Metastatic Squamous NSCLC.
Jiangsu Cancer Institute & Hospital
NCT06199895 RECRUITING Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Liu Huang
NCT06424067 RECRUITING Phase 2 Study of Fingolimod in Lung Cancers
Medical University of South Carolina
NCT06343064 RECRUITING Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKI
Avistone Biotechnology Co., Ltd.
NCT06574347 RECRUITING Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC.
Avistone Biotechnology Co., Ltd.
NCT04152499 ACTIVE NOT RECRUITING Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)
Klus Pharma Inc.
NCT06659042 RECRUITING Perioperative Tislelizumab for Resectable II-IIIB(N2) KRAS-mutated Nonsquamous Non-small Cell Lung Cancer
Shanghai Chest Hospital
NCT06055465 RECRUITING Neoadjuvant Sacituzumab Govitecan Plus Pembrolizumab in Resectable Non-Small Cell Lung Cancer
Chinese University of Hong Kong
NCT06165419 RECRUITING Definitive Radiation for High-Risk Spine Metastases
Stony Brook University
NCT06437509 RECRUITING A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd.
NCT02983578 ACTIVE NOT RECRUITING Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer
M.D. Anderson Cancer Center
NCT06014827 RECRUITING Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma
City of Hope Medical Center
NCT04548830 ACTIVE NOT RECRUITING Safety of Lung Cryobiopsy in People With Cancer
Memorial Sloan Kettering Cancer Center
NCT05736731 ACTIVE NOT RECRUITING A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
A2 Biotherapeutics Inc.
NCT06914050 NOT YET RECRUITING Hypofractionated Radiotherapy Followed by Chemo-immunotherapy Induction Therapy
Tianjin Medical University Cancer Institute and Hospital
NCT06926790 RECRUITING Neoadjuvant Nivolumab Plus Ipilimumab in Resectable NSCLC (GALAXY 3)
The First Affiliated Hospital of Guangzhou Medical University
NCT06936644 NOT YET RECRUITING A Multicenter, Single-arm Phase II Study to Evaluate the Efficacy and Safety of Fulzerasib (IBI351) in Combination With Ivonescimab (AK-112) in First-line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer Patients With KRAS G12C Mutation
Shanghai Chest Hospital
NCT06495125 RECRUITING Defactinib, Avutometinib and Nivolumab for the Treatment of Anti-PD1 Refractory LKB1-Mutant Advanced Non-Small Cell Lung Cancer
Emory University
NCT05144529 ACTIVE NOT RECRUITING A Randomized Pilot Study of Evolocumab Plus Nivolumab/Ipilimumab in Treatment-Naïve Patients With Metastatic NSCLC
Scott Antonia
NCT06120803 RECRUITING Esomeprazole and Radiation Induced Esophagitis
Rush University Medical Center
NCT06918782 NOT YET RECRUITING Real-world Experience With Combination Chemotherapy and Osimertinib in Poor Prognostic Group of Metastatic EGFR-mutated Lung Adenocarcinoma
The University of Hong Kong
NCT05012254 ACTIVE NOT RECRUITING Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases
Fundación GECP
NCT05800587 RECRUITING Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer
Fox Chase Cancer Center
NCT06660407 RECRUITING Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer
Mayo Clinic
NCT03290534 RECRUITING Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®
CivaTech Oncology
NCT06015503 RECRUITING A Phase Ⅱ Study Assessing the Safety and Efficacy of PLB1004 in EGFR ex20ins Mutation Patients With Advanced and Metastatic Non-small Cell Lung Cancer(NSCLC)
Avistone Biotechnology Co., Ltd.
NCT06896890 RECRUITING Cisplatin (CIS) Administered As Dry Powder for Inhalation (DPI) in Patients with Stage IV Non-Small Cell Lung Cancer
Inhatarget Therapeutics
NCT06883552 NOT YET RECRUITING An Open-label, Single-arm Clinical Study of Stapokibart Injection in Combination with Tislelizumab Injection in Patients with Non-Small Cell Lung Cancer
Sichuan University
NCT06730295 RECRUITING Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Centrally Located Early-stage Non-small Cell Lung Cancer
Sun Yat-sen University
NCT06222489 RECRUITING Whole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CT
The Netherlands Cancer Institute
NCT06827145 ACTIVE NOT RECRUITING Combination of Vebreltinib and Osimertinib in Patients with EGFR 21 L858R Mutation Advanced NSCLC
National Cancer Center, China
NCT06816966 ENROLLING BY INVITATION Chemotherapy-immunotherapy-based Split-course Adaptive Hypofractionated Radiotherapy for Extensive-stage SCLC
Fujian Medical University Union Hospital
NCT06792435 RECRUITING XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.
Evopoint Biosciences Inc.
NCT03589547 ACTIVE NOT RECRUITING Durvalumab and Consolidation SBRT Following Chemoradiation for Locally Advanced Stage III Non-Small Cell Lung
Brown University
NCT06793813 RECRUITING Cadonilimab in Patients (Pts) with Advanced Non-small Cell Lung Cancer (NSCLC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06769295 RECRUITING A Phase II Study of AK112 (PD1/VEGF Bispecific) in Combination with Chemotherapy in Patients with NSCLC
Sichuan University
NCT06749860 RECRUITING Disitamab Vedotin in Combination with Tislelizumab and Bevacizumab in a Phase II Clinical Study of Locally Advanced or Metastatic Non-small Cell Lung Cancer with HER2 Mutation/amplification/expression
Shanghai Pulmonary Hospital, Shanghai, China
NCT06749886 RECRUITING An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting
Shanghai Pulmonary Hospital, Shanghai, China
NCT05572684 ACTIVE NOT RECRUITING A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectable or Metastatic Solid Tumors
NextCure, Inc.
NCT06728852 RECRUITING Efficacy and Safety of Vorolanib Monotherapy As Third-line or Later Treatment for Advanced Non-small Cell Lung Cancer Patients: a Single-arm, Prospective, Open-label Phase II Clinical Study
Li-kun Chen
NCT06728865 RECRUITING Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study
Li-kun Chen
NCT06563999 RECRUITING Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.
Sun Yat-sen University
NCT06426511 RECRUITING ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC
Sun Yat-sen University
NCT03872661 RECRUITING Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC
Sun Yat-sen University
NCT06698965 RECRUITING Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin
Shanghai Chest Hospital
NCT06690671 NOT YET RECRUITING A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC
Shanghai Chest Hospital
NCT05199272 ACTIVE NOT RECRUITING A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies
23andMe, Inc.
NCT06688656 NOT YET RECRUITING Neoadjuvant Chemotherapy Sequentially Combined with Sintilimab in Resectable EGFR-Mutant NSCLC
Shanghai Chest Hospital
NCT03769103 ACTIVE NOT RECRUITING Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC
British Columbia Cancer Agency
NCT06667154 RECRUITING Efficacy Analysis of Neoadjuvant Treatment in Lung Cancer Using Low-dose Nivolumab Combined With Chemotherapy
Aline Fusco Fares, MD
NCT04899908 RECRUITING Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
Dana-Farber Cancer Institute
NCT05400070 ACTIVE NOT RECRUITING Neoadjuvant PD-1 Inhibitor (Sintilimab), Anlotinib Combined With Chemotherapy in Resectable Stage IIA-IIIB NSCLC
Tang-Du Hospital
NCT05501665 RECRUITING Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer
Vanderbilt-Ingram Cancer Center
NCT05620134 ACTIVE NOT RECRUITING Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer
Salubris Biotherapeutics Inc
NCT06193239 RECRUITING Diagnostic Accuracy Study for OWL-EVO1 As a Lung Cancer EVOC® Probe (Evolution Phase 2)
Owlstone Ltd
NCT06607770 RECRUITING Safety and Efficacy of Cryoablation With Karelizumab and Apatinib for Multiple Lung Cancers
Zhou Chengzhi
NCT06538012 RECRUITING TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer
Essen Biotech
NCT06497543 NOT YET RECRUITING Intrathecal Pemetrexed for SCLC Patients With Refractory Brain Metastases or Leptomeninges Metastatic
Hunan Province Tumor Hospital
NCT05865990 ACTIVE NOT RECRUITING HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease
MedSIR
NCT06527898 RECRUITING Hypofractionated Radiotherapy Combined with Immunotherapy for Limited-stage Small-cell Lung Cancer
Anhui Provincial Hospital
NCT04951947 RECRUITING JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer
Hunan Province Tumor Hospital
NCT06141226 RECRUITING Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT06586697 RECRUITING First-line Treatment for ES-SCLC with Chemotherapy Combined with PD-1/PD-L1 Inhibitor Sequential Thoracic Radiotherapy
Henan Cancer Hospital
NCT06585644 NOT YET RECRUITING A Clinical Trial of Furmonertinib Combination Therapy As Neoadjuvant Treatment in Resectable EGFR-Mutated NSCLC
Shanghai Pulmonary Hospital, Shanghai, China
NCT05258279 ACTIVE NOT RECRUITING Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR Mutations
Juntendo University
NCT06572722 NOT YET RECRUITING Perioperative Immunotherapy for NSCLC (ECTOP-1030)
Fudan University
NCT06551896 NOT YET RECRUITING Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06006390 RECRUITING CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT06536868 RECRUITING Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC
Second Hospital of Shanxi Medical University
NCT04545710 ACTIVE NOT RECRUITING Osimertinib and Abemaciclib in EGFR Mutant Non-Small Cell Lung Cancer After Osimertinib Resistance
University of California, San Diego
NCT06530719 NOT YET RECRUITING A Study to Evaluate the Efficacy of Osimertinib in Patients With EGFR-sensitive Mutated Non-small Cell Lung Cancer Progression After Receiving Adjuvant Targeted Therapy Following Radical Surgery
Jin Ying
NCT05077709 ACTIVE NOT RECRUITING IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC
IO Biotech
NCT06331455 RECRUITING Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection
Marc de Perrot
NCT04084717 RECRUITING Study of Crizotinib for ROS1 and MET Activated Lung Cancer
University Health Network, Toronto
NCT03540420 ACTIVE NOT RECRUITING Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer
Norwegian University of Science and Technology
NCT06492421 RECRUITING Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.
Second Affiliated Hospital of Guangzhou Medical University
NCT06478043 NOT YET RECRUITING A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC
Zhejiang Cancer Hospital
NCT04216316 ACTIVE NOT RECRUITING Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT06483347 RECRUITING Checkpoint Inhibitor Combinations Therapy as First Line for Inoperable Lung Cancer Via IT
Second Affiliated Hospital of Guangzhou Medical University
NCT05187338 RECRUITING Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT05060432 ACTIVE NOT RECRUITING Study of EOS-448 With Standard of Care and/or Investigational Therapies in Participants With Advanced Solid Tumors
iTeos Belgium SA
NCT06110572 RECRUITING Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation
Vanderbilt-Ingram Cancer Center
NCT05765825 RECRUITING Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC
Sichuan University
NCT06463171 NOT YET RECRUITING Phase II Trial of Almonertinib Plus Lastet for EGFR+ Non-small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China
NCT06456138 NOT YET RECRUITING Trametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLC
Shanghai Chest Hospital
NCT05269381 RECRUITING Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Mayo Clinic
NCT06434740 NOT YET RECRUITING A Study of SBRT Combined With Puterizumab in Intrapulmonary Metastasis From NSCLC
Sir Run Run Shaw Hospital
NCT06421298 RECRUITING A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.
Jinghui Wang
NCT06217757 RECRUITING Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC
Sichuan University
NCT06383728 RECRUITING Neoadjuvant Targeted Therapy in Patients With Resectable EGFR-mutated Lung Squamous Cell Carcinoma
The First Affiliated Hospital of Guangzhou Medical University
NCT05859217 NOT YET RECRUITING A Study of Combining Cabozantinib and Atezolizumab for Advanced/Metastatic NSCLC (Cabatezo-1)
Jun Zhang, MD, PhD
NCT03804580 ACTIVE NOT RECRUITING First-line Treatment With Osimertinib in EGFR-mutated Non-small Cell Lung Cancer
Vestre Viken Hospital Trust
NCT06381960 RECRUITING Clinical Study on the Prevention and Treatment of Postoperative Metastasis of Lung Cancer by Fuzheng Quxie Recipe
Jianhui Tian
NCT04085250 ACTIVE NOT RECRUITING Study of Nivolumab for Non-Small Cell Lung Cancer (Stage III) Following Neoadjuvant Chemotherapy Plus Nivolumab and Definitive Concurrent Chemoradiation Therapy
Sun Yat-sen University
NCT04808752 ACTIVE NOT RECRUITING Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases
Zhejiang Cancer Hospital
NCT06375109 NOT YET RECRUITING PD-L1/PD-1 Inhibitors Plus Chemotherapy Versus Chemotherapy Alone for the Neoadjuvant Treatment of Limited-stage SCLC
Beijing Chest Hospital, Capital Medical University
NCT05358548 RECRUITING ATATcH Alternating Treatment Plans for Advanced Cancer
Rutgers, The State University of New Jersey
NCT06223711 RECRUITING Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC
Universität des Saarlandes
NCT06332950 NOT YET RECRUITING Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy
Baohui Han
NCT06319950 NOT YET RECRUITING High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases
Taizhou Hospital
NCT05669586 RECRUITING Organoids Predict Therapeutic Response in Patients With Multi-line Drug-resistant Lung Cancer
Affiliated Hospital of Jiangnan University
NCT06032052 RECRUITING Single-drug Chemotherapy Plus Immunotherapy in Metastatic Non-small Cell Lung Cancer Elderly Patients
Hubei Cancer Hospital
NCT05801133 RECRUITING Pifenidone Prophylactic Therapy for Radiation Lung Injury in Patients Who Have Previously Received Immune Checkpoint Inhibitors
Hubei Cancer Hospital
NCT06306560 NOT YET RECRUITING A Study of Adebrelimab Combined With Famitinib and Chemotherapy in the Treatment of ES-SCLC.
Harbin Medical University
NCT03654105 ACTIVE NOT RECRUITING Screening and Multiple Intervention on Lung Epidemics
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
NCT05904379 RECRUITING AK112 and AK104 With or Without Chemotherapy in Advanced Non-small Cell Lung Cancer
Akeso
NCT06022757 RECRUITING Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)
Evopoint Biosciences Inc.
NCT06229340 RECRUITING Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations
N.N. Petrov National Medical Research Center of Oncology
NCT06198907 NOT YET RECRUITING Golidocitinib in Combination With Sintilimab for PD-L1 Selected Treatment Locally Advanced or Metastatic Non-Small Cell Lung Cancer(NSCLC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04459065 RECRUITING Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery
University of Saskatchewan
NCT04235114 RECRUITING Evaluation of 89Zr-DFO-nimotuzumab for Non-invasive Imaging of EGFR+ Cancers by Positron Emission Tomography (PET)
University of Saskatchewan
NCT04405401 RECRUITING Stereotactic Ablative Radiotherapy for Oligo-Progressive Non Small Cell Lung Cancer
Centre hospitalier de l'Université de Montréal (CHUM)
NCT05502913 RECRUITING Fecal Microbiota Transplantation With Immune Checkpoint Inhibitors in Lung Cancer
Soroka University Medical Center
NCT06028633 NOT YET RECRUITING Efficacy and Safety of Nab-paclitaxel-Lenvatinib-Pembrolizumab as Second-line Treatment in Advanced NSCLC Patients
Peking University First Hospital
NCT04539977 RECRUITING PD-L1 Antibody (TQB2450) Plus Chemotherapy for Previously Untreated Limited- Stage Small-cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China
NCT05784974 NOT YET RECRUITING Cadonilimab Monotherapy as Neoadjuvant Therapy for Resectable II-IIIA Squamous Cell Lung Cancer
The First Hospital of Jilin University
NCT05784142 ACTIVE NOT RECRUITING Chemo-immunotherapy Induction Followed by Hypo-radiotherapy in LA-NSCLC(CHIC)
Jiangsu Cancer Institute & Hospital
NCT05733000 RECRUITING CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors
Northwestern University
NCT05484583 NOT YET RECRUITING Durvalumab Combined With Consolidation Radiotherapy After First-line Treatment in Extensive Stage Small Cell Lung Cancer With Oligometastases
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
NCT05053802 RECRUITING Efficiency and Safety of Microwave Ablation Plus Immune Checkpoint Inhibitor for Patients With Multiple Primary Lung Cancer: A Open, Multi-center, Phase II Clinical Trial
Shanghai Pulmonary Hospital, Shanghai, China
NCT04237805 RECRUITING A Phase I/II Clinical Study of SAF-189s in Non-small Cell Lung Cancer (NSCLC) Patients
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
NCT04785287 TERMINATED Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies
M.D. Anderson Cancer Center
NCT05566223 WITHDRAWN CISH Inactivated TILs in the Treatment of NSCLC
Intima Bioscience, Inc.
NCT02513563 COMPLETED AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT04515004 TERMINATED Leucoselect Phytosome for Neoadjuvant Treatment of Early Stage Lung Cancer
VA Office of Research and Development
NCT02917993 COMPLETED An Open-Label Phase 1/2 Study of Itacitinib in Combination With Osimertinib in Subjects With Non-Small Cell Lung Cancer
Incyte Corporation
NCT05551117 TERMINATED A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors
MacroGenics
NCT04184921 COMPLETED Combination of Osimertinib and Aspirin to Treat EGFR Mutation NSCLC Patients
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
NCT03575793 COMPLETED A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer
Salma Sabbour
NCT05860296 TERMINATED Testing Experimental Anti-cancer Drug SLC-391 With an Approved Immunotherapy Drug, Pembrolizumab, for Advanced Lung Cancers
SignalChem Lifesciences Corporation
NCT06219174 SUSPENDED Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC (DFMO)
H. Lee Moffitt Cancer Center and Research Institute
NCT05664971 COMPLETED JS004 Combined With Toripalimab and With Standard Chemotherapy Treat Patients With Advanced Lung Cancer
Shanghai Junshi Bioscience Co., Ltd.
NCT03132532 COMPLETED Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Mayo Clinic
NCT04396535 TERMINATED Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer
Mayo Clinic
NCT05194735 TERMINATED Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors
Alaunos Therapeutics
NCT04504916 TERMINATED A Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT03581487 COMPLETED Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT04964960 TERMINATED Pembro+Chemo in Brain Mets
John L. Villano, MD, PhD
NCT04524689 TERMINATED Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Platinum-based Chemotherapy With or Without Pemetrexed in Patients With NSQ NSCLC
Sanofi
NCT05215951 TERMINATED Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLC
AstraZeneca
NCT03184571 COMPLETED Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
BerGenBio ASA
NCT04681131 COMPLETED CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC
BioAtla, Inc.
NCT05815862 COMPLETED Clinical Study of AL2846 Capsules in the Treatment of Advanced Lung Tumor and Advanced Ovarian Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04262856 COMPLETED Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer
Arcus Biosciences, Inc.
NCT06555263 WITHDRAWN Study to Investigate Luveltamab Tazevibulin in Adults With Advanced or Metastatic Non-small Cell Lung Cancer
Sutro Biopharma, Inc.
NCT03322540 COMPLETED Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)
Incyte Corporation
NCT06236516 COMPLETED One Fraction Simulation-Free Treatment With CT-Guided Stereotactic Adaptive Radiotherapy for Patients With Oligometastatic and Primary Lung Tumors
Washington University School of Medicine
NCT04581824 TERMINATED Efficacy Comparison of Dostarlimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC)
GlaxoSmithKline
NCT05420636 TERMINATED Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET
Fox Chase Cancer Center
NCT03862131 TERMINATED PROactive Evaluation of Function to Avoid CardioToxicity
Washington University School of Medicine
NCT04120454 COMPLETED Ramucirumab and Pembrolizumab for the Treatment of EGFR Mutant Recurrent or Metastatic Non-small Cell Lung Cancer
Ohio State University Comprehensive Cancer Center
NCT05879484 WITHDRAWN Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS
National Cancer Institute (NCI)
NCT05253053 COMPLETED To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT03292133 TERMINATED A Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung Cancer
Massachusetts General Hospital
NCT06140407 TERMINATED Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer
Vanderbilt-Ingram Cancer Center
NCT04902040 TERMINATED Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies
M.D. Anderson Cancer Center
NCT04441138 TERMINATED Chemoradiation Followed by Durvalumab in Poor Risk and/or Elderly Patients With Stage III NSCLC
Rush University Medical Center
NCT05840770 WITHDRAWN Cemiplimab for the Treatment of Untreated Brain Metastases From PD-L1 >= 50% Non-Small Cell Lung Cancer
City of Hope Medical Center
NCT04314895 COMPLETED Trial of NanoPac Intratumoral Injection in Lung Cancer
NanOlogy, LLC
NCT03845296 COMPLETED Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
SWOG Cancer Research Network
NCT04671303 COMPLETED To Evaluate the Efficacy and Safety of Anlotinib Combined With Furmonertinib Mesylate in Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT03554473 COMPLETED M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers
National Cancer Institute (NCI)
NCT03212469 COMPLETED A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer
Gustave Roussy, Cancer Campus, Grand Paris
NCT06003075 TERMINATED Induction Chemo-Nivo in Unresectable Stage III NSCLC
Ralph G Zinner
NCT05275673 TERMINATED A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer
Faeth Therapeutics
NCT04496674 TERMINATED Bispecific PSMAxCD3 Antibody CC-1 in Patients With Squamous Cell Carcinoma of the Lung
German Cancer Research Center
NCT02496585 COMPLETED Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis
Memorial Sloan Kettering Cancer Center
NCT03735095 TERMINATED Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer
Roswell Park Cancer Institute
NCT04383210 TERMINATED Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Elevation Oncology
NCT06145048 COMPLETED Phase 2B Safety and Efficacy Study of VGT-309 in Subjects With Cancer in the Lung.
Vergent Bioscience, Inc.
NCT03526887 COMPLETED Re-challenge Pembrolizumab Study as a Second or Further Line in Patients With Advanced NSCLC
Spanish Lung Cancer Group
NCT05137067 COMPLETED A Novel Approach for Alleviating the Side Effects of Chemotherapeutic Agents.
Optimal Health Research
NCT04003246 COMPLETED Phase II Concurrent Durvalumab and Radiotherapy for for Stage III Non-Small Cell Lung Cancer
University of Texas Southwestern Medical Center
NCT04172506 COMPLETED A Study to Evaluate the Efficacy and Safety of Anti-PD-1 Antibody AK105 in Patients With Selected Advanced Solid Tumors
Akeso
NCT03058289 COMPLETED A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Intensity Therapeutics, Inc.
NCT05000684 COMPLETED Study of JS004 Combined With Toripalimab for Advanced Lung Cancer
Shanghai Junshi Bioscience Co., Ltd.
NCT04357873 COMPLETED Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations
UNICANCER
NCT04538378 TERMINATED Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors
National Cancer Institute (NCI)
NCT05309629 COMPLETED Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy in Extensive-Stage Small Cell Lung Cancer
Qilu Pharmaceutical Co., Ltd.
NCT03069924 COMPLETED Gain-framed Messages and NRT for Lung Cancer Screening Patients
Medical University of South Carolina
NCT04923776 TERMINATED Liver Directed RT + Chemo-immunotherapy for ES-SCLC
Brian Henick, MD
NCT04364048 TERMINATED Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer
Rachel Sanborn
NCT03232138 COMPLETED Clinical Trial of Lung Cancer Chemoprevention With Sulforaphane in Former Smokers
Jian-Min Yuan, MD
NCT04789668 COMPLETED Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases
M.D. Anderson Cancer Center
NCT02428764 WITHDRAWN Neoadjuvant Nimotuzumab Plus Gemcitabine and Carboplatin in Unresectable Stage III Squamous Cell Lung Carcinoma
Sun Yat-sen University
NCT03164694 WITHDRAWN APatinib Plus Chemotherapy vErsus Chemotherapy As First-line Treatment for Advanced NSCLC
Sun Yat-sen University
NCT02347839 WITHDRAWN NEoadjuvant Gefitinib fOllowed by Surgery and gefiTinib In unresectAble sTage III NSCLC With EGFR Mutations.
Sun Yat-sen University
NCT06227897 WITHDRAWN Aumolertinib in EGFR-Mutant Resected Stage IB-IIIA NSCLC (AERESA).
Sun Yat-sen University
NCT02495233 TERMINATED A Study of ASP2215 in Combination With Erlotinib in Subjects With Epidermal Growth Factor Receptor (EGFR) Activating Mutation-Positive (EGFRm+) Advanced Non-Small-Cell Lung Cancer (NSCLC) Who Have Acquired Resistance to an EGFR Tyrosine Kinase Inhibitor (TKI)
Astellas Pharma Global Development, Inc.
NCT04951115 TERMINATED A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung Cancer
Weill Medical College of Cornell University
NCT03761914 COMPLETED Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers
Sellas Life Sciences Group
NCT05048082 COMPLETED A Study to Evaluate Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies
OncoNano Medicine, Inc.
NCT04987281 WITHDRAWN Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study
M.D. Anderson Cancer Center
NCT03432598 COMPLETED Anti-PD-1 in Combination With Chemotherapy as First-Line Treatment to Lung Cancer
BeiGene
NCT05400226 COMPLETED Phase 2 Study of VGT-309 in Lung Cancer
Vergent Bioscience, Inc.
NCT03583086 COMPLETED Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors
Vanderbilt-Ingram Cancer Center
NCT04768296 COMPLETED Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)
EMD Serono Research & Development Institute, Inc.
NCT02264210 COMPLETED Icotinib for Completed Resected IB NSCLC With EGFR Mutation
Sun Yat-sen University
NCT06024941 WITHDRAWN Re-induction of a Systemic Immune Response in Metastatic or Locally Recurrent Lung Cancer
Maastricht Radiation Oncology
NCT02664181 COMPLETED Rational EpigenetiC Immunotherapy for SEcond Line Therapy in Patients With NSCLC: PRECISE Trial
Case Comprehensive Cancer Center
NCT04173507 COMPLETED Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial)
SWOG Cancer Research Network
NCT03971474 COMPLETED Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)
SWOG Cancer Research Network
NCT04944173 WITHDRAWN SCION: SABR and Checkpoint Inhibition of NSCLC
University of British Columbia
NCT02431676 COMPLETED Survivorship Promotion In Reducing IGF-1 Trial
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05849246 TERMINATED The Study of Tusamitamab Ravtansine (IBI126) Combined With Sintilimab and Tusamitamab Ravtansine (IBI126) Combined With Sintilimab Plus Platinum-based Chemotherapy and Pemetrexed in Subjects With CEACAM5 Positive Expression Advanced/Metastatic Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)
Innovent Biologics (Suzhou) Co. Ltd.
NCT03417895 COMPLETED SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy
Jiangsu HengRui Medicine Co., Ltd.
NCT03127098 TERMINATED QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer
NantCell, Inc.
NCT04931420 WITHDRAWN Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
University of Chicago
NCT04198818 TERMINATED A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors
Haihe Biopharma Co., Ltd.
NCT05981924 COMPLETED Perioperative Music Therapy Plus Oxycodone in Perioperative Management of Lung Surgery
Hao Long
NCT05364645 WITHDRAWN Testing the Use of Targeted Treatment for RET Positive Advanced Non-small Cell Lung Cancer
SWOG Cancer Research Network
NCT05572476 WITHDRAWN Lurbinectedin Combined With Durvalumab in Pre-treated Patients With Extensive Stage Small-cell Lung Cancer
Institut Bergonié
NCT03847519 COMPLETED Study of ADXS-503 With or Without Pembro in Subjects With Metastatic Non-Small Cell Lung Cancer
Advaxis, Inc.
NCT05411107 WITHDRAWN Oral Iloprost for the Prevention of Lung Cancer In Former Smokers
National Cancer Institute (NCI)
NCT03146962 COMPLETED High Dose Vitamin C Intravenous Infusion in Patients With Resectable or Metastatic Solid Tumor Malignancies
Weill Medical College of Cornell University
NCT04742959 COMPLETED Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT04647344 COMPLETED A Study of AK104 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer
Akeso
NCT04772053 TERMINATED Molecular Disease Characterization Initiative (MDCI)
GlaxoSmithKline
NCT04027946 TERMINATED LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
National Cancer Institute (NCI)
NCT05338580 WITHDRAWN Clinical Trial of TJ271 Injection Combined With Pembrolizumab in the Treatment of Advanced Solid Tumors
TJ Biopharma Co., Ltd.
NCT03076164 COMPLETED A Phase 1/2 Trial of Trametinib and Erlotinib in Patients With EGFR-Mutant Lung Adenocarcinomas and Acquired Resistance to Erlotinib
Memorial Sloan Kettering Cancer Center
NCT04610684 TERMINATED Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases
Jeffrey Clarke
NCT03665285 COMPLETED A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors
NextCure, Inc.
NCT03190239 WITHDRAWN Efficacy and Safety of Maintenance Apatinib Combined With Pemetrexed in Advanced Non-squamous Non-small Cell Lung Cancer Patients
Xinqiao Hospital of Chongqing
NCT04238169 COMPLETED Clinical Trial Assessing the Efficacy of Abscopal Effect Induced by SBRT and Immunotherapy in Advanced NSCLC
Xinqiao Hospital of Chongqing
NCT04491084 TERMINATED FLT3 Ligand, CD40 Agonist Antibody, and Stereotactic Radiotherapy
Albert Einstein College of Medicine
NCT05703555 WITHDRAWN INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701
Erasmus Medical Center
NCT03360630 COMPLETED Anti-PD-1 Alone or Combined With Autologous Cell Therapy in Advanced NSCLC
Capital Medical University
NCT02768337 TERMINATED Cambridge Brain Mets Trial 1
Cambridge University Hospitals NHS Foundation Trust
NCT02709720 COMPLETED Study of Vinorelbine and Cisplatin as Induction Therapy With Radiotherapy in Patients With Unresectable NSCLC
Spanish Lung Cancer Group
NCT04939662 COMPLETED Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects
Se-Hoon Lee
NCT05363605 TERMINATED A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours
Fusion Pharmaceuticals Inc.
NCT05948462 WITHDRAWN Lorlatinib in Combination With Chemotherapy in Participants With Metastatic Anaplastic Lymphoma Kinase Positive (ALK+) Non-small Cell Lung Cancer (NSCLC) Who Progressed on Single-agent Lorlatinib
SCRI Development Innovations, LLC
NCT03871153 TERMINATED Chemoradiation Plus Durvalumab Followed by Surgery Followed by Adjuvant Durvalumab in Patients With Surgically Resectable Stage III (N2) Non-Small Cell Lung Cancer
Greg Durm, MD
NCT02407171 COMPLETED Evaluating the Combination of MK-3475 and Sterotactic Body Radiotherapy in Patients With Metastatic Melanoma or NSCLC
Yale University
NCT03995667 TERMINATED Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer
OHSU Knight Cancer Institute
NCT02321540 COMPLETED A Phase I/II Study of Ibrutinib in Previously Treated Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT04648189 WITHDRAWN Cetuxibab to Reduce Circulating Tumor Cells in Early Stage NSCLC
The Netherlands Cancer Institute
NCT05161533 WITHDRAWN Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial
University of Washington
NCT04989283 WITHDRAWN Testing the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy Treatment During Radiation Therapy for Superior Sulcus Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT02803203 COMPLETED Osimertinib and Bevacizumab as Treatment for EGFR-mutant Lung Cancers
Memorial Sloan Kettering Cancer Center
NCT04790409 COMPLETED Sintilimab Combined With Anlotinib in Advanced NSCLC With EGFR Uncommon Mutations
Zhejiang Cancer Hospital
NCT05045404 WITHDRAWN Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT05935774 WITHDRAWN OT-101 in Combination With Atezolizumab for the Treatment of Metastatic or Recurrent Non-Small Cell Lung Cancer
University of Washington
NCT03083808 COMPLETED Phase II Trial of Continuation Therapy in Advanced NSCLC
Greg Durm, MD
NCT05027867 TERMINATED KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer
Kartos Therapeutics, Inc.
NCT04639245 TERMINATED Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer
Fred Hutchinson Cancer Center
NCT03602079 COMPLETED Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Klus Pharma Inc.
NCT03662074 TERMINATED Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer
Wake Forest University Health Sciences
NCT04971187 TERMINATED Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT03345810 COMPLETED Durvalumab (MEDI4736) in Frail and Elder Patients With Metastatic NSCLC (DURATION)
AIO-Studien-gGmbH
NCT04372927 TERMINATED ADMIRAL Trial: Adaptive Mediastinal Radiation With Chemo-Immunotherapy
University of Washington
NCT03113851 COMPLETED Abscopal Effect of Radiation in Combination With rhGM-CSF for Metastatic Non-small Cell Lung Cancer
Peking University Cancer Hospital & Institute
NCT05411679 WITHDRAWN EP0057 in Combination With Olaparib in Relapsed Advanced Gastric Cancer and Small Cell Lung Cancer
Ellipses Pharma
NCT03827850 TERMINATED FGFR Inhibitor in FGFR Dysregulated Cancer
Lung Cancer Group Cologne
NCT03373760 COMPLETED Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer
SWOG Cancer Research Network
NCT04699968 WITHDRAWN A Trial of SHR-1701 With or Without Famitinib in Patients With Advanced or Metastatic NSCLC
Jiangsu HengRui Medicine Co., Ltd.
NCT03233724 TERMINATED Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas
National Cancer Institute (NCI)
NCT03455829 COMPLETED G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer
G1 Therapeutics, Inc.
NCT04863248 TERMINATED Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Docetaxel for Metastatic Non-Small Cell Lung Cancer (NSCLC) (PRESERVE 4)
G1 Therapeutics, Inc.
NCT02659059 COMPLETED Nivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer
Bristol-Myers Squibb
NCT03406715 TERMINATED Combination Immunotherapy-Ipilimumab-Nivolumab-Dendritic Cell p53 Vac - Patients With Small Cell Lung Cancer (SCLC)
H. Lee Moffitt Cancer Center and Research Institute
NCT02872701 COMPLETED OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
On Target Laboratories, LLC
NCT02393248 TERMINATED Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)
Incyte Corporation
NCT04634110 TERMINATED Brigatinib Before Brain Irradiation Trial (B3i Trial)
University of Colorado, Denver
NCT02448225 COMPLETED 18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules
Vanderbilt-Ingram Cancer Center
NCT02293005 COMPLETED Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma
M.D. Anderson Cancer Center
NCT04265534 TERMINATED KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC
Calithera Biosciences, Inc
NCT02967133 TERMINATED A Study of Nivolumab +/- Nab-paclitaxel in Non-small Cell Lung Cancer
Alliance Foundation Trials, LLC.
NCT03325166 TERMINATED Pembrolizumab and Magnetic Resonance Imaging With Ferumoxytol in Treating Patients With Non-small Cell Lung Cancer and Brain Metastases
OHSU Knight Cancer Institute
NCT02404441 COMPLETED Phase I/II Study of PDR001 in Patients With Advanced Malignancies
Novartis Pharmaceuticals
NCT04069936 TERMINATED Marrow Infiltrating Lymphocytes - Non-Small Cell Lung Cancer (MILs™ - NSCLC) Alone or in Combination With Nivolumab With or Without Tadalafil in Locally Advanced and Unresectable or Metastatic NSCLC
WindMIL Therapeutics
NCT04560686 TERMINATED Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT03041181 TERMINATED Single Agent Chemotherapy +/- Nivolumab in Patients With Advanced Squamous or Non-squamous NSCLC With Primary Resistance to Prior PD-1 or PDL-1 Inhibitor
Nasser Hanna, M.D.
NCT02920476 COMPLETED TAS-102 in Previously Treated Unresectable or Metastatic Squamous Cell Lung Carcinoma (UF-STO-LUNG-003)
University of Florida
NCT05022394 WITHDRAWN Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study
M.D. Anderson Cancer Center
NCT02385812 TERMINATED Screening of Alberta Asbestos Exposed Workers for Lung Cancer and Mesothelioma
University of Calgary
NCT03770299 WITHDRAWN An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease
Bristol-Myers Squibb
NCT04061590 WITHDRAWN Pembrolizumab With or Without Chemotherapy Before Surgery in Treating Patients With Stage I-IIIA Non-Small Cell Lung Cancer
University of California, San Francisco
NCT04470674 WITHDRAWN Study of Durvalumab or Durvalumab Plus Chemotherapy in Kras Mutation Positive and PD-L1 High (≥ 50%) NSCLC Patients
Shirish M Gadgeel
NCT03088930 COMPLETED Evaluating Crizotinib in the Neoadjuvant Setting in Patients With Non-small Cell Lung Cancer
University of Colorado, Denver
NCT03321760 WITHDRAWN SABR for T1-2a N1 NSCLC
Indiana University
NCT04928950 WITHDRAWN Charcoal in Lung Cancer Patients Undergoing TEMLA
Masonic Cancer Center, University of Minnesota
NCT03322566 COMPLETED A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)
Incyte Corporation
NCT02318277 COMPLETED A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)
Incyte Corporation
NCT03245736 COMPLETED Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.
Seagen Inc.
NCT03371979 COMPLETED Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancer
Aeglea Biotherapeutics
NCT04262869 WITHDRAWN Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer
Emory University
NCT03574753 COMPLETED Lung-MAP S1400K: c-MET Positive
SWOG Cancer Research Network
NCT03377556 COMPLETED Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer
SWOG Cancer Research Network
NCT02475330 TERMINATED Dietary Flaxseed in NSCLC
Abramson Cancer Center at Penn Medicine
NCT03597009 TERMINATED A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion
UNC Lineberger Comprehensive Cancer Center
NCT02552121 COMPLETED Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors
Seagen Inc.
NCT02450903 COMPLETED LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.
Novartis Pharmaceuticals
NCT02733250 COMPLETED Pembrolizumab With Nab-Paclitaxel in Non-Small Cell Lung Cancer
Centre hospitalier de l'Université de Montréal (CHUM)
NCT02577341 COMPLETED Nimotuzumab Combined With Chemoradiotherapy for Unresectable Locally Advanced Squamous Cell Lung Cancer
Sun Yat-sen University
NCT03044626 COMPLETED Fostering Efficacy of Anti - PD-1 - Treatment: Nivolumab Plus Radiotherapy in Advanced NSCLC
AIO-Studien-gGmbH
NCT02525653 COMPLETED Albumin-Bound Paclitaxel and Gemcitabine in Patients With Untreated Stage IV or Recurrent Squamous Cell Lung Cancers
Memorial Sloan Kettering Cancer Center
NCT02276027 COMPLETED A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer
Novartis Pharmaceuticals
NCT03547804 COMPLETED A Prospective, Single-center, One-arm Clinical Study of Apatinib Combined With Chemotherapy for Pretreated Patients With Advanced Small Cell Lung Cancer
The First Hospital of Jilin University
NCT04267913 WITHDRAWN Testing of TAK228 (MLN0128, Sapanisertib) Plus Docetaxel to the Usual Standard of Care for Advanced Squamous Cell Lung Cancer (A Lung-MAP Treatment Trial)
SWOG Cancer Research Network
NCT03256136 COMPLETED Nivolumab in Combination With Chemotherapy, or Nivolumab in Combination With Ipilimumab, in Advanced EGFR-Mutant or ALK-Rearranged NSCLC
Massachusetts General Hospital
NCT03501056 WITHDRAWN Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Lung Cancer
Fuda Cancer Hospital, Guangzhou
NCT03086733 COMPLETED Phase II Lung Metcore - Preoperative Metformin for Lung Cancer
University Health Network, Toronto
NCT03183232 COMPLETED Safety and Efficiency of γδ T Cell Against Lung Cancer
Fuda Cancer Hospital, Guangzhou
NCT03704870 COMPLETED Outcomes Following Omission of Daily Routine Chest Radiographs Following Pulmonary Resection
University Health Network, Toronto
NCT02713984 WITHDRAWN A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer
Zhi Yang
NCT03574818 TERMINATED Necitumumab in the Neoadjuvant Setting With Gemcitabine in Surgically Resectable - 14X-US-I001
Montefiore Medical Center
NCT03763851 TERMINATED Cannabis Oil and Radiation Therapy for the Management of Pain
Tetra Bio-Pharma
NCT02469701 TERMINATED Advanced Non-Small Cell Lung Cancer Progressing After at Least One Prior Therapy For Metastatic Disease
howard safran
NCT02285855 TERMINATED Metformin in Non Small Cell Lung Cancer (NSCLC)
M.D. Anderson Cancer Center
NCT03684967 WITHDRAWN Study of Fruquintinib (HMPL-013) in High Risk Patients With Advanced NSCLC
Hutchison Medipharma Limited
NCT02425748 COMPLETED Safety and Efficiency of γδ T Cell Against Non Small Lung Cancer ( Without EGFR Mutation)
Fuda Cancer Hospital, Guangzhou
NCT02466568 WITHDRAWN Study of Nivolumab in Combination With GM.CD40L Vaccine in Adenocarcinoma of the Lung
H. Lee Moffitt Cancer Center and Research Institute
NCT02271906 TERMINATED The ATTAIN Study: A Therapeutic Trial of Afatinib In the Neoadjuvant Setting
M.D. Anderson Cancer Center
NCT02595840 TERMINATED Biomarker Study Accompanying the AIO-TRK-0114 Study (MARBLE)
Universität Duisburg-Essen
NCT02976883 COMPLETED [18F]HX4 PET/CT Imaging for Detection of Hypoxia
Nottingham University Hospitals NHS Trust
NCT02763761 WITHDRAWN An Investigational Study of Infliximab With Prednisone or Methylprednisolone Versus Prednisone Combination Treatment in Immune Related or Severe Diarrhea in Patients Treated With Yervoy and/or Opdivo
Bristol-Myers Squibb
NCT02672358 WITHDRAWN Study of Efficacy and Safety of Dabrafenib and Trametinib Combination Therapy in Japanese Patients With BRAF V600E Stage IV NSCLC
Novartis Pharmaceuticals
NCT03240393 WITHDRAWN Study of Oral cMET Inhibitor INC280 in Chinese Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (NSCLC)
Novartis Pharmaceuticals
NCT03353428 WITHDRAWN Intervention of Engineered Immune Effector T Cells Against Lung Cancer
Shenzhen Geno-Immune Medical Institute
NCT03004105 WITHDRAWN MEDI4736 With Selumetinib for KRAS Mutant Non-Small Cell Lung Cancer (NSCLC)
M.D. Anderson Cancer Center
NCT02166658 TERMINATED A Study of Cabazitaxel for Patients With Breast or Lung Cancer and Recurrent or Progressive Brain Metastases - Cabazitaxel for Brain Metastases (CaBaMet)
AIO-Studien-gGmbH
NCT02488694 TERMINATED Maintaining ERBB Blockade in EGFR-mutated Lung Cancer
AIO-Studien-gGmbH
NCT02950038 WITHDRAWN Study of Ibrutinib Followed by Ibrutinib in Combination With Nivolumab in Non-Small Cell Lung Cancer (NSCLC)
M.D. Anderson Cancer Center
NCT02416570 TERMINATED Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer?
University of Nottingham
NCT02523404 COMPLETED HepaSphere Interventional Therapy Using Digital Subtraction Angiography(DSA)for Lung Cancer
Fuda Cancer Hospital, Guangzhou
NCT02449122 COMPLETED Nano Drug Interventional Therapy Using Digital Subtraction Angiography(DSA) for Lung Carcinoma
Fuda Cancer Hospital, Guangzhou
NCT02536495 WITHDRAWN Selinexor and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Lung Cancer
Erin Bertino