TheraRadar

Pharma Intelligence, Simplified

Landscape → Cardiovascular

Heart Failure

739 clinical trials

262 active
/
739 total (since 2015)
46
Phase 1 Active
152 total
104
Phase 2 Active
287 total
63
Phase 3 Active
159 total
84
Phase 4 Active
219 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Novo Nordisk 5 2 0
AstraZeneca 3 20 6
Tasly Pharmaceutical Group Co., Ltd 3 2 0
Bayer 2 12 1
Boehringer Ingelheim 2 6 0
Cytokinetics 2 3 1
Sarfez Pharmaceuticals, Inc. 2 1 2
Salubris Biotherapeutics Inc 2 1 1
Help Therapeutics 2 1 0
Fujian Shengdi Pharmaceutical Co., Ltd. 2 1 0
Heartseed Inc. 2 0 0
Shandong Suncadia Medicine Co., Ltd. 2 0 0
AskBio Inc 2 0 0
Beijing Suncadia Pharmaceuticals Co., Ltd 2 0 0
Sardocor Corp. 2 0 0
NCT06578078 RECRUITING
A Clinical Trial to Define the Best Strategy for the Management of Heart Failure in Elderly Patients
Fundación para la Investigación del Hospital Clínico de Valencia n=94
NCT07037459 RECRUITING
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen n=5,056
NCT06128980 RECRUITING
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
Herlev and Gentofte Hospital n=348
NCT06008197 RECRUITING
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Colorado Prevention Center n=5,200
NCT06935370 RECRUITING
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Boehringer Ingelheim n=4,200
NCT06677060 RECRUITING
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
AstraZeneca n=11,300
NCT05714085 RECRUITING
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC n=342
NCT06424288 RECRUITING
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim n=6,000
NCT06307652 RECRUITING
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
AstraZeneca n=4,800
NCT06736574 RECRUITING
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Cytokinetics n=1,800
NCT05825573 ACTIVE NOT RECRUITING
Anticoagulation Therapy in Non-device-related Intra-cardiac Thrombus
Centre Hospitalier Universitaire de Nīmes n=340
NCT05392764 RECRUITING
Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure
Juntendo University n=444
NCT05636176 RECRUITING
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
Novo Nordisk A/S n=5,600
NCT07399587 RECRUITING
Optimizing HFrEF Patients Using BaroStim and CardioMems
Northwell Health n=15
NCT06200207 RECRUITING
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
Novo Nordisk A/S n=680
NCT07192952 NOT YET RECRUITING
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Bayer n=117
NCT07188805 RECRUITING
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Bayer n=111
NCT06518694 RECRUITING
Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction
Assistance Publique - Hôpitaux de Paris n=1,300
NCT07018297 NOT YET RECRUITING
Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure
University of Texas Southwestern Medical Center n=250
NCT06027307 ACTIVE NOT RECRUITING
Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation
Asan Medical Center n=541
NCT07038356 RECRUITING
Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure
Christian Schulze n=536
NCT07288749 NOT YET RECRUITING
Efficacy Evaluation of Glimepiride in Patients With Type 2 Diabetes Mellitus and Chronic Heart Failure With Reduced Ejection Fraction.
Tongji Hospital n=1,484
NCT00610051 NOT YET RECRUITING
ALP-1 Continuous Intravenous Infusion to Maintain Clinical Stability in Advanced Heart Failure
Biopeutics Co., Ltd n=600
NCT04982419 RECRUITING
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
VA Office of Research and Development n=240
NCT05613218 RECRUITING
Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
Copenhagen University Hospital, Hvidovre n=122
NCT07270367 NOT YET RECRUITING
Finerenone and Cardiac Remodeling
Subodh Verma n=156
NCT07262723 NOT YET RECRUITING
Levosimendan in Acute Decompensated Heart Failure
Chittagong Medical College n=332
NCT05374291 ENROLLING BY INVITATION
The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD
University Medical Center Groningen n=1,750
NCT06898515 RECRUITING
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Reprieve Cardiovascular, Inc n=400
NCT07234422 NOT YET RECRUITING
The SELEQT-HF (SELEnium and CoQ10 NuTrition for Heart Failure) Study Will Evaluate the Effect of Adding Selenium/and coQ10 on Top of Standard HF Therapy in Patients With HF and Will do so Using a Pragmatic, Registry Based Randomized Controlled Trial in the Netherlands.
Netherlands Heart Institute n=1,100
NCT07223242 RECRUITING
Tailored Exercise Training Study Among Adults With HFpEF
University of Texas Southwestern Medical Center n=120
NCT05887271 RECRUITING
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
University of Leicester n=63
NCT06694727 RECRUITING
A Danish Pragmatic Randomized Trial of Nutritional Supplements in Heart Failure
Tor Biering-Sørensen n=4,044
NCT06217302 RECRUITING
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Alessandro Doria n=150
NCT06349941 RECRUITING
Home-based Cardiac Rehabilitation in Heart Failure
University of Texas Southwestern Medical Center n=332
NCT07090343 NOT YET RECRUITING
Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement
Leiden University Medical Center n=826
NCT06929806 RECRUITING
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
Pharmacosmos A/S n=1,900
NCT06566183 NOT YET RECRUITING
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial
NYU Langone Health n=1,200
NCT05873881 RECRUITING
COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease
Hamilton Health Sciences Corporation n=2,500
NCT07008365 RECRUITING
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Instituto de Investigación Sanitaria Aragón n=168
NCT06946095 NOT YET RECRUITING
Efficacy and Safety of Xinyue Capsule in the Treatment of Heart Failure With Preserved Ejection Fraction
Beijing Anzhen Hospital n=246
NCT06033950 RECRUITING
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists
Colorado Prevention Center n=2,600
NCT06024746 RECRUITING
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF)
Colorado Prevention Center n=1,500
NCT06837623 ACTIVE NOT RECRUITING
Role of Colchicine as Anti-Inflammatory Therapy in HFpEF
Cairo University n=75
NCT06619600 ACTIVE NOT RECRUITING
Effect of Dapagliflozin in Myocardial Fibrosis and Ventricular Function in Patients With a ST-segment Elevation Myocardial Infarction
Hospital Clinic of Barcelona n=54
NCT02984124 ACTIVE NOT RECRUITING
Communication During Hospitalization About Resuscitation Trial
University of Vermont n=182
NCT06783166 RECRUITING
Assessing the Clinical Outcomes of Dapagliflozin Versus Acetazolamide in Patients With Acute Heart Failure
Mansoura University n=100
NCT06082063 RECRUITING
Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes
Steno Diabetes Center Copenhagen n=2,000
NCT06158698 RECRUITING
CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine
Niguarda Hospital n=80
NCT06304857 RECRUITING
CardioPROTECTion with Dapagliflozin in Breast Cancer Patients Treated with AnthrAcycline - PROTECTAA TRIAL
4th Military Clinical Hospital with Polyclinic, Poland n=188
NCT06683053 ACTIVE NOT RECRUITING
Evaluation of the Use of Empagliflozin in Patients with HF with PEF in a Cardiology Outpatient Department
Conrado Roberto Hoffmann Filho n=90
NCT05508035 RECRUITING
The Effect of Sacubitril/valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients with Ischemic Heart Failure with Mid-range Ejection Fraction
John Paul II Hospital, Krakow n=666
NCT02901184 RECRUITING
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Uppsala University n=2,000
NCT06630923 RECRUITING
PREVENTION OF WORSENING RENAL FUNCTION OF INTRAVENUS ALBUMIN IN HEART FAILURE PATIENTS
Democritus University of Thrace n=250
NCT04201015 RECRUITING
Optimising Pacing for Contractility 2
University of Leeds n=400
NCT05824923 RECRUITING
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Pulnovo Medical (Wuxi) Co., Ltd. n=264
NCT06535529 RECRUITING
Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
Helwan University n=60
NCT06434025 NOT YET RECRUITING
IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency
Hospital de Clinicas de Porto Alegre n=99
NCT06423599 RECRUITING
Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure
Jens D Hove, MD,PHD n=100
NCT06405555 NOT YET RECRUITING
Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension
Ottawa Heart Institute Research Corporation n=56
NCT06044194 RECRUITING
Evaluation of the Effect of Liposomal L-Arg and Vit C Integration on Mitochondrial Function in Patients With Heart Failure
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico n=56
NCT06142474 RECRUITING
SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning
National Taiwan University Hospital n=450
NCT05553886 RECRUITING
S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction
Shenzhen People's Hospital n=5
NCT04158674 TERMINATED
Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS
Centre Hospitalier Universitaire Dijon n=82
NCT05668676 COMPLETED
Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )
Assistance Publique - Hôpitaux de Paris n=3
NCT05858320 COMPLETED
The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients
University of Michigan n=225
NCT04551222 COMPLETED
The Re-Prosper HF Study
VA Office of Research and Development n=99
NCT05093933 COMPLETED
A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)
Merck Sharp & Dohme LLC n=6,106
NCT04916470 COMPLETED
Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes
Novo Nordisk A/S n=617
NCT03296813 COMPLETED
TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure
Duke University n=2,973
NCT06149104 COMPLETED
A Safety Study of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study
Novartis Pharmaceuticals n=8
NCT02438306 COMPLETED
CardiAMP™ Cell Therapy for Heart Failure Trial
BioCardia, Inc. n=125
NCT04986202 COMPLETED
Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40%
AstraZeneca n=711
NCT04435626 COMPLETED
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%
Bayer n=6,016
NCT04847557 COMPLETED
A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial
Eli Lilly and Company n=731
NCT05676684 COMPLETED
Dapagliflozin With or Without Spironolactone for HFpEF
Universidade do Porto n=108
NCT05237323 COMPLETED
Micophenolate Mofetil Versus Azathioprine in Myocarditis
I.M. Sechenov First Moscow State Medical University n=50
NCT07023016 COMPLETED
Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart Failure
National Heart Institute, Egypt n=515
NCT04600921 TERMINATED
Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study
Medical University of Graz n=55
NCT03341156 TERMINATED
Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation
University of Maryland, Baltimore n=14
NCT03833336 COMPLETED
Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF)
Institut de Recerca Biomèdica de Lleida n=72
NCT03785405 COMPLETED
Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF
Novartis Pharmaceuticals n=216
NCT04536272 COMPLETED
Reduced Anticoagulation Targets in ECLS (RATE)
University Medical Center Groningen n=330
NCT04252287 COMPLETED
A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
Janssen Research & Development, LLC n=476
NCT04727073 TERMINATED
Spironolactone in the Treatment of Heart Failure
Charite University, Berlin, Germany n=743
NCT04564742 COMPLETED
Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack.
AstraZeneca n=4,017
NCT03988634 COMPLETED
Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)
Novartis Pharmaceuticals n=467
NCT05652322 WITHDRAWN
Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure
Jan Kochanowski University
NCT05949801 COMPLETED
Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. n=202
NCT03717194 COMPLETED
Effect of Ertugliflozin on Cardiac Function in Diabetes
Soo Lim n=102
NCT05043610 COMPLETED
MSCs for Prevention of MI-induced HF
Shiraz University of Medical Sciences n=420
NCT05093621 COMPLETED
Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
Yale University n=47
NCT04755816 TERMINATED
A Mobile Application to Promote Self-management and Improve Outcomes in Heart Failure
University of Michigan n=62
NCT03255226 COMPLETED
Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
Otsuka Pharmaceutical Co., Ltd. n=60
NCT02884206 COMPLETED
Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction
Novartis Pharmaceuticals n=592
NCT04468529 COMPLETED
Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. n=154
NCT05364190 COMPLETED
Canagliflozin in Patients With Acute Decompansted Heart Failure
October 6 University n=142
NCT03037931 COMPLETED
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency / and Sub-Study
American Regent, Inc. n=3,065
NCT05962255 COMPLETED
Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure
Wroclaw Medical University n=50
NCT04705987 COMPLETED
Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia n=279
NCT04298229 COMPLETED
Efficacy and Safety of Dapagliflozin in Acute Heart Failure
Vanderbilt University Medical Center n=240
NCT03917459 COMPLETED
COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure
Novartis Pharmaceuticals n=27
NCT04415658 COMPLETED
Intravenous Thyroxine for Heart-Eligible Organ Donors
Washington University School of Medicine n=838
NCT03991000 TERMINATED
Iron in Patients With Cardiovascular Disease
Dr. med. Mahir Karakas n=8
NCT02468232 COMPLETED
Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction
Novartis Pharmaceuticals n=225
NCT02592824 COMPLETED
Glutamate for Metabolic Intervention in Coronary Surgery II
University Hospital, Linkoeping n=321
NCT04533997 COMPLETED
Hypertonic Saline Therapy in Ambulatory Heart Failure Unit.
Puerta de Hierro University Hospital n=167
NCT04738279 COMPLETED
The CASCADE HF Soft Launch and Calibration Phase I and II
Endeavor Health n=20
NCT05406505 COMPLETED
Effect of Dapagliflozin in Patients With Acute Heart Failure (DAPA-RESPONSE-AHF)
Mansoura University n=87
NCT03745898 TERMINATED
The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
Brigham and Women's Hospital n=98
NCT04707352 COMPLETED
Impact on Atrial Remodeling of Dapaglifozin in Patients With Heart Failure .
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia n=162
NCT03619213 COMPLETED
Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.
AstraZeneca n=6,263
NCT03552575 COMPLETED
The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MI
NHS Greater Glasgow and Clyde n=93
NCT03759392 COMPLETED
Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure
Cytokinetics n=276
NCT03458325 COMPLETED
Furoscix Real-World Evaluation for Decreasing Hospital Admissions in Heart Failure
scPharmaceuticals, Inc. n=27
NCT02678312 COMPLETED
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure
Novartis Pharmaceuticals n=393
NCT04507347 WITHDRAWN
Efficacy and Safety of TRC041266 in Patients With Heart Failure, LVEF ≥40%, Diastolic Dysfunction and Type 2 Diabetes Mellitus
Torrent Pharmaceuticals Limited
NCT02329834 COMPLETED
Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure
scPharmaceuticals, Inc. n=23
NCT03315143 TERMINATED
Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk
Lexicon Pharmaceuticals n=10,584
NCT03521934 TERMINATED
Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)
Lexicon Pharmaceuticals n=1,222
NCT03884504 COMPLETED
MDT-1118 Japan DT Study
Medtronic Cardiac Rhythm and Heart Failure n=10
NCT03359161 TERMINATED
Clinical Utility of Subcutaneous Furosemide in Patients Presenting With Early Signs of Fluid Overload
Steward St. Elizabeth's Medical Center of Boston, Inc. n=9
NCT02674438 COMPLETED
Comparison of Outcomes and Access to Care for Heart Failure Trial
Institute for Clinical Evaluative Sciences n=5,452
NCT04157751 COMPLETED
A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure
Boehringer Ingelheim n=530
NCT03057951 COMPLETED
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
Boehringer Ingelheim n=5,988
NCT02809131 COMPLETED
Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.
Vanderbilt University Medical Center n=1,010
NCT03926754 COMPLETED
Beta 3 Agonist Treatment in Heart Failure-2
Henning Bundgaard n=56
NCT03877224 COMPLETED
DETERMINE-preserved - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Preserved Ejection Fraction
AstraZeneca n=504
NCT02861534 COMPLETED
A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-001)
Merck Sharp & Dohme LLC n=5,050
NCT02929329 COMPLETED
Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction
Cytokinetics n=8,256
NCT03066804 COMPLETED
A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients
Novartis Pharmaceuticals n=2,572
NCT03909295 TERMINATED
An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan.
Novartis Pharmaceuticals n=52
NCT03962101 COMPLETED
Safety Trial of OPC-61815 Injection in Patients With Congestive Heart Failure Who Have Difficulty With or Are Incapable of Oral Intake
Otsuka Pharmaceutical Co., Ltd. n=45
NCT04128891 WITHDRAWN
Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction
Flinders University
NCT03772041 COMPLETED
Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure
Otsuka Pharmaceutical Co., Ltd. n=294
NCT04464525 WITHDRAWN
Omecamtiv Mecarbil Post-trial Access Study
Cytokinetics
NCT03332212 COMPLETED
A Study That Looks at the Function of the Heart in Patients With Heart Failure Who Take Empagliflozin
Boehringer Ingelheim n=72
NCT03057977 COMPLETED
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
Boehringer Ingelheim n=3,730
NCT03877237 COMPLETED
DETERMINE-reduced - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Reduced Ejection Fraction
AstraZeneca n=313
NCT03418233 COMPLETED
Randomized Clinical Trial to Evaluate the Regenerative Capacity of CardioCell in Patients With Chronic Ischaemic Heart Failure (CIHF)
John Paul II Hospital, Krakow n=115
NCT02708771 COMPLETED
Effect of W-3 Polyunsaturated Fatty Acids on Serum Albumin Concentration in Patients With Acute Heart Failure, Hypoalbuminemia, and High Inflammatory Activity
Hospital San Juan de la Cruz n=42
NCT03448406 COMPLETED
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Preserved Ejection Fraction (HFpEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms.
Boehringer Ingelheim n=315
NCT03448419 COMPLETED
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms
Boehringer Ingelheim n=312
NCT04628325 COMPLETED
Effects of Furosemide Plus Small HSS in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)
University of Palermo n=136
NCT03037580 TERMINATED
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
United Therapeutics n=84
NCT02900378 COMPLETED
randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure
Novartis Pharmaceuticals n=621
NCT03036124 COMPLETED
Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure
AstraZeneca n=4,744
NCT02598505 COMPLETED
Indacaterol in Heart Failure Patients: Any Role on Lung Fluid Regulation
Centro Cardiologico Monzino n=44
NCT02869022 COMPLETED
Study of Organ Perfusion With Custodiol-N Solution Compared With Custodiol Solution in Heart Transplantation
Dr. F. Köhler Chemie GmbH n=105
NCT02585843 COMPLETED
Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance
Columbia University n=20
NCT02488525 TERMINATED
Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support
University Hospital, Lille n=31
NCT03360448 WITHDRAWN
AC6 Gene Transfer in Patients With Reduced Left Ventricular Ejection Fraction Heart Failure
Renova Therapeutics
NCT02656329 TERMINATED
International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device
GE Healthcare n=395
NCT02885636 COMPLETED
Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
Mayo Clinic n=30
NCT02620384 TERMINATED
Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure (MELT-HF)--A Single Center Pilot Study.
Aultman Health Foundation n=147
NCT03102827 TERMINATED
High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure
Heart and Diabetes Center North-Rhine Westfalia n=14
NCT02804282 COMPLETED
Product Design Clinical Performance Study of sc2Wear Furosemide Combination Product
scPharmaceuticals, Inc. n=74
NCT02579057 COMPLETED
Sub-Q Versus IV Furosemide in Acute Heart Failure
Johns Hopkins University n=40
NCT02998697 COMPLETED
Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemia
National Cardiovascular Center Harapan Kita Hospital Indonesia n=54

Data: ClinicalTrials.gov