Landscape → Ophthalmology

Glaucoma

225 clinical trials

63 active

225 total (since 2015)

Phase 1 Active

47 total

Phase 2 Active

67 total

Phase 3 Active

74 total

Phase 4 Active

58 total

Top Sponsors (Industry)

Sorted by active Active Done Failed

AbbVie 4 9 0

Glaukos Corporation 4 5 0

Qlaris Bio, Inc. 3 6 0

SpyGlass Pharma, Inc. 3 0 0

PolyActiva Pty Ltd 2 3 0

Amneal Pharmaceuticals, LLC 2 0 0

Alcon Research 1 5 1

Santen Pharmaceutical Co., Ltd. 1 6 0

Laboratoires Thea 1 3 0

Bausch & Lomb Incorporated 1 2 0

EyeD Pharma 1 0 1

Life Biosciences Inc. 1 0 0

Huons Co., Ltd. 1 0 0

IVIEW Therapeutics Inc. 1 0 0

Perfuse Therapeutics, Inc. 1 0 0

NCT07075718 RECRUITING

Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Glaukos Corporation n=610

NCT06822738 RECRUITING

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

AbbVie n=130

NCT07354516 NOT YET RECRUITING

Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension

Qlaris Bio, Inc. n=36

NCT06066645 RECRUITING

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

Glaukos Corporation n=230

NCT07335211 RECRUITING

Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Huons Co., Ltd. n=206

NCT07082816 ACTIVE NOT RECRUITING

Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction

Alcon Research n=489

NCT05695027 ACTIVE NOT RECRUITING

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

Columbia University n=250

NCT03933631 RECRUITING

Pilocarpine Use After Kahook Goniotomy

Montefiore Medical Center n=142

NCT07218783 RECRUITING

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)

SpyGlass Pharma, Inc. n=400

NCT07218796 RECRUITING

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

SpyGlass Pharma, Inc. n=400

NCT03891446 ACTIVE NOT RECRUITING

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

AbbVie n=455

NCT06666855 RECRUITING

A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China

Santen Pharmaceutical Co., Ltd. n=338

NCT06731582 ENROLLING BY INVITATION

Nicotinamide Supplementation in Glaucoma

Singapore Eye Research Institute n=520

NCT06680245 NOT YET RECRUITING

Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery

St. Joseph's Healthcare Hamilton n=144

NCT06061718 ACTIVE NOT RECRUITING

Travoprost Intraocular Implant in Conjunction With Cataract Surgery

Glaukos Corporation n=60

NCT05405868 RECRUITING

Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial

University College, London n=496

NCT05710198 RECRUITING

Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma

Omikron Italia S.r.l. n=1,000

NCT05401357 RECRUITING

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

Amneal Pharmaceuticals, LLC n=168

NCT05411198 COMPLETED

Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma

AbbVie n=74

NCT05938699 COMPLETED

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution

Nicox Ophthalmics, Inc. n=18

NCT04630808 COMPLETED

MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Nicox Ophthalmics, Inc. n=696

NCT02390284 TERMINATED

Stop Retinal Ganglion Cell Dysfunction Study

University of Miami n=28

NCT03850782 COMPLETED

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

AbbVie n=515

NCT04445519 COMPLETED

Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Nicox Ophthalmics, Inc. n=691

NCT06431113 COMPLETED

Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in Glaucoma

Fondazione IRCCS Policlinico San Matteo di Pavia n=40

NCT04944290 COMPLETED

To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Padagis LLC n=447

NCT05583474 COMPLETED

OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects

Otsuka Beijing Research Institute n=204

NCT03193333 TERMINATED

PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)

Laboratorios Sophia S.A de C.V. n=51

NCT03519386 COMPLETED

Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%

Glaukos Corporation n=590

NCT03868124 COMPLETED

Clinical Study Comparing Two Models of a Travoprost Intraocular Implant

Glaukos Corporation n=560

NCT05397600 COMPLETED

Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients

Laboratoires Thea n=684

NCT05503901 COMPLETED

A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension

Santen Pharmaceutical Co., Ltd. n=131

NCT02801617 TERMINATED

Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension

Laboratorios Sophia S.A de C.V. n=116

NCT02507687 COMPLETED

Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension

AbbVie n=240

NCT02981446 COMPLETED

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Santen Pharmaceutical Co., Ltd. n=370

NCT03235232 COMPLETED

BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension

EMS n=406

NCT05022004 COMPLETED

A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Sun Pharmaceutical Industries Limited n=599

NCT05495061 COMPLETED

A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Santen Pharmaceutical Co., Ltd. n=325

NCT03825380 COMPLETED

Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous Patients

Laboratoires Thea n=485

NCT05042609 COMPLETED

A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

Tarsier Pharma n=142

NCT05973318 COMPLETED

Comparative Study of Dorzotimol Eye Drops, 20 mg/mL + 5 mg/mL Versus Cosopt® Eye Drops, 20 mg/mL + 5 mg/mL

Jadran Galenski laboratorij d.d. n=110

NCT05973305 COMPLETED

Comparative Study of Dorzol Eye Drops, 20 mg/ml Versus Trusopt® Eye Drops, 20 mg/ml

Jadran Galenski laboratorij d.d. n=118

NCT04061044 COMPLETED

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Ocular Therapeutix, Inc. n=40

NCT04285580 COMPLETED

A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension

AbbVie n=37

NCT03362931 COMPLETED

Safety and Effectiveness of the XEN45 Glaucoma Treatment System in Patients With Angle Closure Glaucoma

Allergan n=65

NCT02617459 COMPLETED

Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension

Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. n=366

NCT04024072 COMPLETED

To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Padagis LLC n=495

NCT04620135 COMPLETED

Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Aerie Pharmaceuticals n=245

NCT04890106 COMPLETED

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% to LUMIGAN® In The Treatment of Chronic Open-Angle Glaucoma

Mankind Pharma Limited n=310

NCT05127525 TERMINATED

EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN)

iRenix Medical, Inc. n=5

NCT04005079 WITHDRAWN

Pilocarpine After Combined Cataract/Trabectome Surgery

Montefiore Medical Center

NCT02636946 COMPLETED

A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

Allergan n=144

NCT03450629 COMPLETED

Evaluation of Safety and Efficacy of PDP-716

Sun Pharma Advanced Research Company Limited n=682

NCT03284853 COMPLETED

Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension

Aerie Pharmaceuticals n=436

NCT03927443 WITHDRAWN

A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertension

Sun Pharmaceutical Industries Limited

NCT04563559 WITHDRAWN

PREFERENTIAL Study

Duke University

NCT02914509 COMPLETED

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Ocular Therapeutix, Inc. n=565

NCT02767219 COMPLETED

The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery

Moorfields Eye Hospital NHS Foundation Trust n=6

NCT02731118 TERMINATED

Antisecretory Factor (AF) Effects on Intraocular-pressure

St. Erik Eye Hospital n=50

NCT04052269 SUSPENDED

Phosphodiesterase Inhibitors in Glaucoma Study (PhiGS)

Imperial College London n=30

NCT04455126 COMPLETED

Preservative-free Tafluprost Eye Drops in Newly Diagnosed Patients With Glaucoma

Alexandria University n=30

NCT03639675 COMPLETED

Study to Learn How the Drug Aflibercept Works in in Japanese Patients With Increased Eye Pressure That is Caused by New Blood Vessels Growing in the Eye (Neovascular Glaucoma or NVG). Safety of the Drug and Patients' Tolerability of the Drug Injection is Also Studied

Bayer n=16

NCT02512042 COMPLETED

Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes

Actavis Inc. n=973

NCT03257813 COMPLETED

Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)

Laboratorios Sophia S.A de C.V. n=60

NCT03419975 COMPLETED

A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients

Taejoon Pharmaceutical Co., Ltd. n=146

NCT02558400 COMPLETED

Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Aerie Pharmaceuticals n=718

NCT02674854 COMPLETED

Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Aerie Pharmaceuticals n=750

NCT02339584 COMPLETED

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Alcon Research n=493

NCT02558374 COMPLETED

Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

Aerie Pharmaceuticals n=708

NCT02822729 COMPLETED

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Santen Pharmaceutical Co., Ltd. n=125

NCT02623738 COMPLETED

A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-

Santen Pharmaceutical Co., Ltd. n=253

NCT02822742 COMPLETED

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Santen Pharmaceutical Co., Ltd. n=26

NCT02396316 COMPLETED

Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients

Bayer n=54

NCT02565173 COMPLETED

Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma

Inotek Pharmaceuticals Corporation n=303

NCT07354477 RECRUITING

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

Qlaris Bio, Inc.

NCT06030193 ACTIVE NOT RECRUITING

Study of an Investigational Product, QLS-111, Provided as an Eyedrop, for Treatment of Normal Tension Glaucoma (NTG)

Qlaris Bio, Inc.

NCT04499248 RECRUITING

AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

AbbVie

NCT05426044 RECRUITING

Metformin as a Neuroprotective Therapy for Glaucoma

Christopher Kai Shun Leung

NCT07168902 RECRUITING

Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension

Bausch & Lomb Incorporated

NCT04577300 ACTIVE NOT RECRUITING

Dual Intravitreal Implantation of NT-501 Encapsulated Cell Therapy for Glaucoma

Stanford University

NCT02862938 ACTIVE NOT RECRUITING

Study of NT-501 Encapsulated Cell Therapy for Glaucoma Neuroprotection and Vision Restoration

Stanford University

NCT06921317 RECRUITING

GVB-2001 Gene Therapy Via Intracameral Injection for the Treatment of Primary Open Angle Glaucoma

IVIEW Therapeutics Inc.

NCT06120842 ACTIVE NOT RECRUITING

Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution

SpyGlass Pharma, Inc.

NCT05694858 RECRUITING

Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting

Universiti Kebangsaan Malaysia Medical Centre

NCT06991712 RECRUITING

Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients

Christopher Kai Shun Leung

NCT06964191 RECRUITING

Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular Hypertension

PolyActiva Pty Ltd

NCT05822245 ACTIVE NOT RECRUITING

A Study of PER-001 in Participants With Open-Angle Glaucoma

Perfuse Therapeutics, Inc.

NCT05180994 RECRUITING

Topical Infliximab in Eyes With Penetrating Keratoplasty

Centre hospitalier de l'Université de Montréal (CHUM)

NCT06223048 RECRUITING

A Study of AMDX-2011P in Participants With Primary Open Angle Glaucoma

Amydis Inc.

NCT05389267 ACTIVE NOT RECRUITING

Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients.

Laboratoires Thea

NCT06144918 COMPLETED

Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye Pressure

Skye Bioscience, Inc.

NCT06394973 COMPLETED

Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Laboratoires Thea

NCT06903156 COMPLETED

Efficacy and Safety of Different Dosages of Mexidol® in Patients With Primary Open-angle Glaucoma (POAG)

Pharmasoft

NCT06441643 COMPLETED

Next Generation Rocklatan

Alcon Research

NCT05913232 COMPLETED

Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

D. Western Therapeutics Institute, Inc.

NCT04149899 COMPLETED

Safety and IOP-Lowering Effects of WB007

Bausch & Lomb Incorporated

NCT05335122 COMPLETED

A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Ocular Therapeutix, Inc.

NCT04947124 COMPLETED

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Qlaris Bio, Inc.

NCT06249152 COMPLETED

Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients

Qlaris Bio, Inc.

NCT06016972 COMPLETED

Qlaris Phase 2 Study of QLS-111 in POAG And/or OHT Patients

Qlaris Bio, Inc.

NCT04857827 COMPLETED

A Study to Evaluate Safety and Tolerability of QLS-101 in NTG

Qlaris Bio, Inc.

NCT05495269 COMPLETED

Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP)

Qlaris Bio, Inc.

NCT04830397 COMPLETED

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Qlaris Bio, Inc.

NCT06582732 COMPLETED

Performance of the Travoprost Intraocular Implant

Glaukos Corporation

NCT04761705 SUSPENDED

Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension

JeniVision, Inc.

NCT04910100 COMPLETED

Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension

Betaliq, Inc.

NCT05451329 COMPLETED

A Phase 2 Double-masked Study of VVN539 in Subjects With Elevated Intraocular Pressure

VivaVision Biotech, Inc

NCT02754596 COMPLETED

Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution

Glaukos Corporation

NCT04615403 COMPLETED

Study of Exchange of Travoprost Intraocular Implant

Glaukos Corporation

NCT03960866 COMPLETED

Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma

Ocuphire Pharma, Inc.

NCT04742283 COMPLETED

Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Santen Inc.

NCT03657797 COMPLETED

Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Nicox Ophthalmics, Inc.

NCT04405245 COMPLETED

Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma

EyePoint Pharmaceuticals, Inc.

NCT03896633 COMPLETED

Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt

Bausch & Lomb Incorporated

NCT03959592 TERMINATED

Macular Pigment and Visual Performance in Glaucoma Patients

Felipe Medeiros, MD

NCT03452033 COMPLETED

H-1337 Ophthalmic Solution Phase 1/2

Allysta Pharmaceutical

NCT04747808 COMPLETED

Study of LL-BMT1 in Patients With Elevated Intraocular Pressure

MediPrint Ophthalmics, Inc.

NCT02805257 COMPLETED

Ahmed Glaucoma Valve Surgery With Mitomycin-C

University of California, San Francisco

NCT02466399 COMPLETED

POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma

Peregrine Ophthalmic

NCT03844945 COMPLETED

Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan

Aerie Pharmaceuticals

NCT03292796 COMPLETED

RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery.

Julie Dawson

NCT02358369 COMPLETED

Dose-Ranging Study of the Bimatoprost Ocular Insert

ForSight Vision5, Inc.

NCT04317573 COMPLETED

Effect on the Adherence to Glaucoma Eye Drops by Improving Patient Understanding and Using a Tele-reminder System

National University Health System, Singapore

NCT04205201 COMPLETED

The Effectiveness of Topical Latanoprost Compared With Topical Brimonidine in the Treatment of the Primary Open Angle Glaucoma

Chittagong Medical College

NCT03310580 COMPLETED

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Aerie Pharmaceuticals

NCT04088084 COMPLETED

Effects of Palmitoylethanolamide on Inner Retinal Function in Glaucoma Patients by Pattern Electroretinogram

Fondazione IRCCS Policlinico San Matteo di Pavia

NCT01864317 TERMINATED

Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging

Medical University of Vienna

NCT03233308 COMPLETED

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Aerie Pharmaceuticals

NCT02537015 COMPLETED

An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Insert

ForSight Vision5, Inc.

NCT02742649 COMPLETED

A Study to Evaluate Efficacy and Safety of a Fixed Combination Ocular Insert in Participants With Open-angle Glaucoma or Ocular Hypertension

ForSight Vision5, Inc.

NCT03106532 COMPLETED

Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma

pH Pharma

NCT02743780 COMPLETED

A Three Part Study of MGV354 in Ocular Hypertension or Glaucoma

Alcon Research

NCT02874846 COMPLETED

Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution

Aerie Pharmaceuticals

NCT02829996 COMPLETED

Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAG

Inotek Pharmaceuticals Corporation

NCT07290244 NOT YET RECRUITING

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Life Biosciences Inc.

NCT06964061 RECRUITING

Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension

PolyActiva Pty Ltd

NCT05206877 RECRUITING

Topical Insulin for Glaucoma

Stanford University

NCT07036510 RECRUITING

Safety of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery

EyeD Pharma

NCT04844619 ACTIVE NOT RECRUITING

KDR2-2 Suspension Eyedrop in the Treatment of Neovascular Glaucoma (KDR-NVG) Trial

Sun Yat-sen University

NCT04118920 ACTIVE NOT RECRUITING

Safety of Topical Insulin Drops for Open-angle Glaucoma

Centre hospitalier de l'Université de Montréal (CHUM)

NCT06267274 RECRUITING

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Amneal Pharmaceuticals, LLC

NCT06506305 NOT YET RECRUITING

Clinical Study of FB1001 in Patients

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

NCT04060758 COMPLETED

Open Label, Sequential-dose Study of PA5108 Latanoprost FA SR Ocular Implant for Mild-moderate Glaucoma

PolyActiva Pty Ltd

NCT04500574 TERMINATED

Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension

Massachusetts Eye and Ear Infirmary

NCT06321562 TERMINATED

Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucoma

EyeD Pharma

NCT06572397 COMPLETED

Open-Label Study of Safety of H1337 in Healthy Volunteers

D. Western Therapeutics Institute, Inc.

NCT05160805 COMPLETED

A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients with Progressing Open Angle Glaucoma

ONL Therapeutics

NCT04360174 COMPLETED

CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension

Ocular Therapeutix, Inc.

NCT05333419 COMPLETED

Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension.

PolyActiva Pty Ltd

NCT05207761 COMPLETED

Study to Evaluate Drug-drug Interaction, Safety and Tolerability in Case of the Co-administration of D565 and D930

Chong Kun Dang Pharmaceutical

NCT04035239 COMPLETED

Retinal Effects of Balance Goggles System in Glaucoma Balance Goggles System (BGS) in Patients With Glaucoma

Stanford University

NCT02852057 COMPLETED

Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses

University of Florida

NCT03131167 COMPLETED

Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma

Shire

NCT02984813 TERMINATED

Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy

The New York Eye & Ear Infirmary

NCT02855450 COMPLETED

Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With Glaucoma

Dompé Farmaceutici S.p.A

NCT03604328 COMPLETED

Safety and Tolerability of a Prostaglandin Ocular Implant for Treatment of Open Angle Glaucoma

PolyActiva Pty Ltd

NCT03488550 COMPLETED

Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma

Annexon, Inc.

NCT04188015 COMPLETED

Study of ANX007 in Participants With Primary Open-angle Glaucoma

Annexon, Inc.

NCT03293992 COMPLETED

A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Hoffmann-La Roche

NCT04284514 COMPLETED

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solution

Aerpio Therapeutics

NCT03966365 COMPLETED

Safety and Tolerability of the Preservative-free Ophthalmic Solution PRO-122 Compared With Krytantek Ofteno®

Laboratorios Sophia S.A de C.V.

NCT03965052 COMPLETED

Safety and Tolerability of the Ophthalmic Solution PRO-179 Compared With Travatan®

Laboratorios Sophia S.A de C.V.

NCT02639975 COMPLETED

"First-in-human" Study To Assess the Safety and Tolerability of PBF-677 in Healthy Volunteers

Palobiofarma SL

NCT02967614 COMPLETED

KJ-TFC-004 Drug-drug Interaction Study

Kukje Pharma

NCT02622334 COMPLETED

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Hoffmann-La Roche

NCT02406833 COMPLETED

Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing Trabeculectomy

Isarna Therapeutics GmbH

NCT02531152 COMPLETED

28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Sanofi

NCT07408154 NOT YET RECRUITING

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

Medical University of South Carolina

NCT07217678 RECRUITING

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

University of Miami

NCT07396441 RECRUITING

Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye

Universiti Sains Malaysia

NCT06848946 RECRUITING

Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone

Glaukos Corporation

NCT07325240 ACTIVE NOT RECRUITING

24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients

Mayo Clinic

NCT07174401 NOT YET RECRUITING

Rocklatan Retinal Perfusion OCT Study

Oregon Health and Science University

NCT05344274 RECRUITING

Retinal Blood Flow and Autoregulation

University of Maryland, Baltimore

NCT05821855 RECRUITING

A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China

AbbVie

NCT07209410 RECRUITING

Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma

Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,

NCT07228221 RECRUITING

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

Jonathon Myers

NCT04007276 NOT YET RECRUITING

The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients

Tulane University

NCT07048886 NOT YET RECRUITING

Rocklatan Adds Pressure Reduction After MIGS (Minimally Invasive Glaucoma Surgery)

Center for Sight Las Vegas

NCT06865144 RECRUITING

Effect of Rhopressa on Intraocular Pressure (IOP) in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension Post-SLT

East Coast Institute for Research

NCT06883123 RECRUITING

Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost

Prairie Eye Center

NCT06792422 RECRUITING

A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma

Glostrup University Hospital, Copenhagen

NCT06761313 ACTIVE NOT RECRUITING

Triplenex (triple Fixed Combination) Use Evaluation in Patients with Glaucoma

Federal University of São Paulo

NCT06017362 RECRUITING

Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical Hypotensors

Barbara Burgos Blasco

NCT06498440 NOT YET RECRUITING

Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT

St. Joseph's Healthcare Hamilton

NCT06294015 NOT YET RECRUITING

Efficacy of 20% Autologous Serum Drops in the Treatment of Corneal Epitheliopathy Associated With Antihypertensive Glaucoma Drops.

Université de Sherbrooke

NCT05498103 ACTIVE NOT RECRUITING

Use of Methazolamide to Lower Intraocular Pressure

University of Colorado, Denver

NCT04957329 RECRUITING

Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells

Rigshospitalet, Denmark

NCT04412096 COMPLETED

Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance

Ohio State University

NCT06437639 COMPLETED

MEXIDOL® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)

Pharmasoft

NCT06449352 COMPLETED

Effect of Netarsudil vs Brimonidine in NTG Patients on Latanoprost

Westlake Eye Specialists

NCT06539715 COMPLETED

Comparison of Visual Field Assessments Between Three Perimeters

Gainesville Eye Associates

NCT06078592 COMPLETED

Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive

CHA University

NCT06407973 TERMINATED

A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Patients With Primary Open Angle Glaucoma

Sight Sciences, Inc.

NCT05857267 COMPLETED

Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safety

Laboratorios Poen

NCT06369077 TERMINATED

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

CT Glaucoma Associates

NCT04846179 COMPLETED

To Evaluate the Effect of Ginkgo Biloba Extract on Optic Nerve Head Perfusion Examined Using OCTA

Nova Scotia Health Authority

NCT05283395 COMPLETED

Rocklatan® Evaluation

Aerie Pharmaceuticals

NCT04200651 TERMINATED

Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery

The New York Eye Surgery Center

NCT03875911 TERMINATED

Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in Trabeculectomy

University of California, Los Angeles

NCT04702789 TERMINATED

Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension.

Laboratorios Sophia S.A de C.V.

NCT04676126 WITHDRAWN

Augmented Macular Pigment-containing Nutraceutical and Central Visual Function

University of the Incarnate Word

NCT04465864 COMPLETED

Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert

Wolstan and Goldberg Eye Associates

NCT05474716 COMPLETED

The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of POAG Using OCTA

Fayoum University

NCT03654885 COMPLETED

XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS)

Allergan

NCT03949244 COMPLETED

Nailfold Capillary Blood Flow With Latanoprost Bunod

Icahn School of Medicine at Mount Sinai

NCT03648229 WITHDRAWN

African Glaucoma Laser Trial

West Virginia University

NCT04743622 COMPLETED

Comparison of Efficacy and Ocular Surface Disease Assessment Between Monoprost and BAK-preserved Latanoprost

CHA University

NCT03323164 COMPLETED

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

Wills Eye

NCT03612817 COMPLETED

Preservative-free Tafluprost/Timolol Fixed Combination: Morning vs Evening Dosing

Aristotle University Of Thessaloniki

NCT02802137 COMPLETED

24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy

Aristotle University Of Thessaloniki

NCT04654611 COMPLETED

Tafluprost Preservative Free Switch Study

Tun Hussein Onn National Eye Hospital

NCT02796560 COMPLETED

Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Université de Sherbrooke

NCT03808688 COMPLETED

Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting

Aerie Pharmaceuticals

NCT04352660 COMPLETED

Subconjunctival Versus Direct Mitomycin C in Trabeculectomy

University of California, San Diego

NCT04075227 COMPLETED

Topical 0.2% Loteprednol Etabonate vs. Topical 0.1% Dexamethasone in Impending Recurrent Pterygium

Wannisa Suphachearabhan

NCT02730871 TERMINATED

Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®

Alcon Research

NCT03150160 COMPLETED

Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension Glaucoma

Novartis Pharmaceuticals

NCT02419508 COMPLETED

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Alcon Research

NCT03690622 COMPLETED

Effect of Topical Dexmedetomidine on Intraocular Pressure

Beirut Eye Specialist Hospital

NCT02863705 COMPLETED

Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)

Allergan

NCT02571712 COMPLETED

Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertension

Allergan

NCT02770248 COMPLETED

24-hr Intraocular Pressure Control With SIMBRINZA ®

Alcon Research

NCT03331770 COMPLETED

Efficacy and Tolerability of an Innovative Formulation of BAK-free Latanoprost

Laboratorios Poen

NCT03204487 COMPLETED

A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thickness

Ordination Dr. Hommer

Data: ClinicalTrials.gov