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National Cancer Institute (NCI)
NCT06324357 RECRUITING Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Boehringer Ingelheim
NCT04757363 ACTIVE NOT RECRUITING A Study of Nivolumab Combined With FOLFOX and Regorafenib in People Who Have HER2-Negative Esophagogastric Cancer
Memorial Sloan Kettering Cancer Center
NCT03641313 ACTIVE NOT RECRUITING Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer
National Cancer Institute (NCI)
NCT07282912 RECRUITING Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels
Yale University
NCT06461910 RECRUITING Efficacy and Safety of Anti-PD-1, Thymalfasin, and SOX in Neoadjuvant Treatment of cStage III Gastric/Gastroesophageal Junction Adenocarcinoma
Zekuan Xu
NCT07262619 RECRUITING EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Eikon Therapeutics
NCT06047379 RECRUITING Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Neonc Technologies, Inc.
NCT05753306 RECRUITING Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study
Mayo Clinic
NCT07432295 RECRUITING Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)
I-Mab Biopharma US Limited
NCT06695845 RECRUITING A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Jazz Pharmaceuticals
NCT07432633 RECRUITING [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
Blue Earth Diagnostics
NCT05438420 ACTIVE NOT RECRUITING Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors
Qurient Co., Ltd.
NCT04430738 ACTIVE NOT RECRUITING Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers
Seagen, a wholly owned subsidiary of Pfizer
NCT04150640 RECRUITING Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma
University of Wisconsin, Madison
NCT07277439 RECRUITING Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University
NCT06005493 RECRUITING Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors
AstraZeneca
NCT04379596 RECRUITING Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
AstraZeneca
NCT04644068 ACTIVE NOT RECRUITING Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
AstraZeneca
NCT04868877 ACTIVE NOT RECRUITING Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
Merus B.V.
NCT06519591 RECRUITING Systemic Application of Cadonilimab, LM-302, and S-1 Combined With Intraperitoneal Infusion of Paclitaxel for the Treatment of Claudin 18.2-positive Gastric Cancer With Peritoneal Metastasis
Ruijin Hospital
NCT05117931 ACTIVE NOT RECRUITING A Study of Amivantamab in People With Esophagogastric Cancer
Memorial Sloan Kettering Cancer Center
NCT06219941 RECRUITING AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
AstraZeneca
NCT06628310 RECRUITING A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
AbbVie
NCT05671822 RECRUITING Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT07392346 RECRUITING Safety and Efficacy of Fruquintinib Plus Nab-Paclitaxel and Iparomlimab and Tuvonralimab Injection in the Second-Line Treatment for Immunotherapy-experienced Advanced Gastric Cancer
Dai, Guanghai
NCT06921928 RECRUITING Study for AZD4360 in Participants With Advanced Solid Tumours
AstraZeneca
NCT06109467 RECRUITING Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT07391826 NOT YET RECRUITING Megestrol Acetate Oral Suspension for Cachexia in Patients With cStage III Gastric/Gastroesophageal Junction Adenocarcinoma Receiving Neoadjuvant Therapy With Serplulimab Combined With SOX
The First Affiliated Hospital with Nanjing Medical University
NCT06710132 RECRUITING Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)
EMD Serono Research & Development Institute, Inc.
NCT07176312 RECRUITING Zanidatamab in Combination With Pembrolizumab and Chemotherapy in HER2 and PD-L1 Positive Metastatic Gastroesophageal Adenocarcinoma (GEA) Patients
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT07384234 NOT YET RECRUITING SHR-1701 Combined With Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis
Ruijin Hospital
NCT04762953 ACTIVE NOT RECRUITING Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis
University of California, Irvine
NCT04661150 ACTIVE NOT RECRUITING A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction
Hoffmann-La Roche
NCT02734004 ACTIVE NOT RECRUITING A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.
AstraZeneca
NCT06055439 RECRUITING A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy
Chimeric Therapeutics
NCT06123338 RECRUITING A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer
Memorial Sloan Kettering Cancer Center
NCT06172478 RECRUITING A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Daiichi Sankyo
NCT07151040 RECRUITING Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
One-carbon Therapeutics AB
NCT07374250 NOT YET RECRUITING Perioperative Ivonescimab Plus S-1 and Oxaliplatin (SOX) for Locally Advanced Gastric or GEJ Adenocarcinoma
Sichuan University
NCT07266025 NOT YET RECRUITING Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma:A Randomized, Non-comparative Phase 2 Study
Shanghai Zhongshan Hospital
NCT06921837 RECRUITING A First-in-Human Study Using BDC-4182 as a Single Agent in Advanced Gastric and Gastroesophageal Cancer
Bolt Biotherapeutics, Inc.
NCT04421820 RECRUITING BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
Bold Therapeutics, Inc.
NCT07364422 NOT YET RECRUITING To Evaluate the Safety and Tolerability of Study Drug as a Third-line and Beyond Therapy for Recurrent or Metastatic Gastric Cancer
Onconic Therapeutics Inc.
NCT06761846 RECRUITING Sintilimab Combined With Chemotherapy as Adjuvant Treatment for Phase III GC and GEJ
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06808971 RECRUITING Adebrelimab Combined With Nab-paclitaxel, Oxaliplatin and Tegafur (AOS) for Perioperative Treatment of Locally Advanced Resectable GC/GEJ
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05620628 RECRUITING Ph2 Study of Savolitinib and Durvalumab (MEDI4736) Combination in Advanced MET Amplified Gastric Cancer(VIKTORY-2)
Jeeyun Lee
NCT06468280 RECRUITING Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer
Shanghai Zhongshan Hospital
NCT07354711 RECRUITING A First-in-human Study of 3H-10000 in Patients With Unresectable or Metastatic Solid Tumors
3H Pharmaceuticals Co., Ltd.
NCT03539822 RECRUITING Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies
Anwaar Saeed
NCT07143604 RECRUITING A Study to Investigate the Effects of AZD0901 Monotherapy in Adult Participants With 2L+ Advanced or Metastatic Gastric or GEJ Adenocarcinoma Expressing CLDN18.2
AstraZeneca
NCT03257163 ACTIVE NOT RECRUITING Pembrolizumab, Capecitabine, and Radiation Therapy in Treating Patients With Mismatch-Repair Deficient and Epstein-Barr Virus Positive Gastric Cancer
Rutgers, The State University of New Jersey
NCT06710756 RECRUITING Lead-212 PSV359 Therapy for Patients With Solid Tumors
Perspective Therapeutics
NCT02584244 RECRUITING Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
Lumicell, Inc.
NCT03228667 ACTIVE NOT RECRUITING QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
ImmunityBio, Inc.
NCT07059611 NOT YET RECRUITING Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma
Abramson Cancer Center at Penn Medicine
NCT07334431 RECRUITING Fruquintinib Combined With Trastuzumab and XELOX as First-line Treatment in Patients With HER2-positive Advanced Gastric Cancer
Henan Cancer Hospital
NCT07333573 NOT YET RECRUITING A Hypoxia-Inducible CAR-T Cell Targeting AXL and CD73 for Advanced Gastric Cancer
Shanghai Zhongshan Hospital
NCT07110571 RECRUITING A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06399757 RECRUITING A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
Apollo Therapeutics Ltd
NCT07315854 RECRUITING Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer
Beijing Friendship Hospital
NCT07320586 RECRUITING Carilizumab and Albumin Paclitaxel for Second-line Treatment of Advanced Gastric Cancer
Shandong Tumor Hospital
NCT07315035 NOT YET RECRUITING QL1706-SOX vs SOX Alone as Neoadjuvant Therapy for Resectable Diffuse-Type Gastric Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT07311408 RECRUITING SHR-1701 + Rivoceranib (± SHR-2554) in Advanced GC After First-Line Immunotherapy Failure
Jingdong Zhang
NCT07139951 ENROLLING BY INVITATION Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence
Mayo Clinic
NCT07304258 NOT YET RECRUITING A Prospective, Phase II Clinical Study of HIPEC Combined With NIPS and Tislelizumab Conversion Therapy for Gastric Cancer With Peritoneal Metastasis With Positive Cytology Alone or PCI Score ≤10
Hebei Medical University
NCT06962137 RECRUITING Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer
Universitaire Ziekenhuizen KU Leuven
NCT07294664 RECRUITING PD1/TGFβ In Combination With EZH2 And Chemotherapy For First - Line Treatment Of Gastric Cancer
The First Affiliated Hospital of Zhengzhou University
NCT04198766 ACTIVE NOT RECRUITING Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Inhibrx Biosciences, Inc
NCT04396821 ACTIVE NOT RECRUITING A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
Suzhou Transcenta Therapeutics Co., Ltd.
NCT06157892 RECRUITING A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT06943521 RECRUITING A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Tanabe Pharma America, Inc.
NCT05322577 ACTIVE NOT RECRUITING A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer.
Amgen
NCT07101666 NOT YET RECRUITING Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer
Washington University School of Medicine
NCT07263386 RECRUITING A Phase II, Multicenter, Randomized, Controlled Clinical Study Comparing the Efficacy and Safety of Sintilimab Plus SOX Versus SOX Alone as Adjuvant Therapy for PD-L1-Positive, Stage pN3 Gastric Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT04209686 ACTIVE NOT RECRUITING Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03190941 RECRUITING Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
National Cancer Institute (NCI)
NCT07257575 ACTIVE NOT RECRUITING A Randomized Controlled Study of Serplulimab Combined With Chemotherapy for Locally Advanced Gastric Adenocarcinoma
Guangdong Provincial People's Hospital
NCT06333314 RECRUITING Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
UNICANCER
NCT07259226 RECRUITING Optimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Biomarkers
UNICANCER
NCT06251973 RECRUITING A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer
Memorial Sloan Kettering Cancer Center
NCT05836584 ACTIVE NOT RECRUITING Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer
National Cancer Institute (NCI)
NCT06846346 RECRUITING Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenocarcinoma
UNICANCER
NCT07132918 RECRUITING HEARTS Trial for Thoracic Cancers
University of Wisconsin, Madison
NCT06313801 RECRUITING Comparing the Safety and Efficacy of First-line Polychemotherapy and Polychemotherapy in Combination With PIPAC Sessions
Nizhny Novgorod Regional Clinical Oncology Center
NCT07149090 RECRUITING Lenvatinib in Combination With Nivolumab Plus Chemotherapy in Metastatic Gastric Cancer Patients With Malignant Ascites
Asan Medical Center
NCT04982276 RECRUITING A Study of AK109 and AK104 in Advanced Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma
Akeso
NCT05977998 RECRUITING A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology
M.D. Anderson Cancer Center
NCT05438459 RECRUITING GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites
Kyushu University
NCT05702229 RECRUITING Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
AstraZeneca
NCT04656041 RECRUITING Folfox+Irinotecan+Chemort In Esophageal Cancer
Massachusetts General Hospital
NCT06503146 RECRUITING 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
National Cancer Institute (NCI)
NCT06487221 RECRUITING Avutometinib and Defactinib in Diffuse Gastric Cancer
Ryan H. Moy, MD, PhD
NCT03776487 ACTIVE NOT RECRUITING Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer
M.D. Anderson Cancer Center
NCT05205330 ACTIVE NOT RECRUITING Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers
Rottapharm Biotech
NCT03161522 RECRUITING Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer
M.D. Anderson Cancer Center
NCT03505320 ACTIVE NOT RECRUITING A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer
Astellas Pharma Global Development, Inc.
NCT05709574 RECRUITING Tadalafil Effect + Chemotherapy in Resectable Gastric/GEJ Cancer
University of Arizona
NCT06116136 ACTIVE NOT RECRUITING A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.
Servier Bio-Innovation LLC
NCT04931654 ACTIVE NOT RECRUITING A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer
AstraZeneca
NCT04107077 RECRUITING Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer
University of Chicago
NCT05177068 ACTIVE NOT RECRUITING Conversion Therapy of Fruquintinib in Combination With Sintilimab and SOX in Unresectable Gastric Cancer
Henan Cancer Hospital
NCT06008054 RECRUITING A Study of SI-B003, BL-B01D1+SI-B003 and BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Esophageal Cancer, Gastric Cancer, Colorectal Cancer and Other Gastrointestinal Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT07194005 RECRUITING Conversion Therapy With RC48, Sintilimab, and SOX for HER2 1+/2+ Unresectable Gastric Cancer
Fudan University
NCT03745326 RECRUITING Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
National Cancer Institute (NCI)
NCT06253611 RECRUITING First-line EXL01 With Nivolumab and FOLFOX for PD-L1 CPS ≥5 Metastatic Gastric Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group
NCT07178808 RECRUITING PHASE II EVALUATION OF CYTOREDUCTION SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (CRS/HIPEC) IN GASTRIC CANCER
Banner Health
NCT05632939 ACTIVE NOT RECRUITING ASKB589 in Combination With CAPOX and PD-1 Inhibitors in Patients With Advanced, and Unresectable G/GEJ Cancer.
AskGene Pharma, Inc.
NCT07165847 RECRUITING Neoadjuvant Radiotherapy Plus Tegafur, Oxaliplatin and Iparomlimab and Tuvonralimab in Resectable Gastric and GE-junction Cancer : A Randomized, Two-arm, Prospective Trial (TRIUNITE-05)
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
NCT07102901 RECRUITING Safety and Efficacy of SHR2554 Combined With Other Antitumor Therapies in Gastric or Gastro-oesophageal Junction Adenocarcinoma
Jiangsu HengRui Medicine Co., Ltd.
NCT06947291 RECRUITING Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT07007182 NOT YET RECRUITING Conversion Therapy Plus Surgery and Radiotherapy for Retroperitoneal Nodal Metastases in Gastric Cancer
Jinbo Yue
NCT05515796 RECRUITING Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
NCT04111172 ACTIVE NOT RECRUITING A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma
Thomas Jefferson University
NCT05927857 RECRUITING Ramucirumab (Cyramza), Nal-IRI (ONIVYDE) and Trifluridine/Tipiracil (Lonsurf) in Second Line Metastatic Gastric Cancer .
National Health Research Institutes, Taiwan
NCT07133490 NOT YET RECRUITING INTERACT Stomach-II
Erasmus Medical Center
NCT06250036 RECRUITING Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer
Royal Marsden NHS Foundation Trust
NCT05864144 ACTIVE NOT RECRUITING A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Sensei Biotherapeutics, Inc.
NCT07119463 RECRUITING Effect of Goal-Oriented Albumin Infusion on Postoperative Complication Management in Gastric Cancer Surgery
The First Hospital of Jilin University
NCT06298916 RECRUITING 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
Lantheus Medical Imaging
NCT04164979 ACTIVE NOT RECRUITING Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma
University of California, Irvine
NCT05057013 ACTIVE NOT RECRUITING A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours
Cancer Research UK
NCT06395519 RECRUITING A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
858 Therapeutics, Inc.
NCT06038578 RECRUITING A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer
Toray Industries, Inc
NCT04069273 RECRUITING Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma
Harry H Yoon
NCT07085273 NOT YET RECRUITING Irinotecan Liposome II + 5-FU/LV + Oxaliplatin + Karelizumab in Neoadjuvant Treatment of Gastric Cancer
The First Affiliated Hospital of Zhengzhou University
NCT03421288 ACTIVE NOT RECRUITING Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT07070466 NOT YET RECRUITING Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA
Massachusetts General Hospital
NCT05379972 ACTIVE NOT RECRUITING Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers
University of Colorado, Denver
NCT06427252 ACTIVE NOT RECRUITING The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM
The First Affiliated Hospital with Nanjing Medical University
NCT05489211 RECRUITING Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
AstraZeneca
NCT05894824 RECRUITING T-Dxd in Combination With Ramucirumab as HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Yonsei University
NCT04592211 RECRUITING Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer
Yonsei University
NCT03935893 RECRUITING Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
Udai Kammula
NCT05086692 RECRUITING A Beta-only IL-2 ImmunoTherapY Study
Medicenna Therapeutics, Inc.
NCT07053332 NOT YET RECRUITING A Study on Immunotherapy Combined With Radiotherapy for Esophagogastric Junction/Gastric Adenocarcinoma
Jiangsu Cancer Institute & Hospital
NCT07050524 NOT YET RECRUITING Omega-3 Supplementation and Immunotherapy in Gastric Cancer: A Phase II Trial
The First Affiliated Hospital with Nanjing Medical University
NCT03093688 RECRUITING Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor
Shanghai Public Health Clinical Center
NCT07045805 NOT YET RECRUITING Phase II Study of QL1706 Combined With Paclitaxel and Bevacizumab for Second-Line Immune Rechallenge in Gastric Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT06895447 RECRUITING Robotic Gastrectomy for Locally Advanced Gastric Cancer After Neoadjuvant Therapy
The First Affiliated Hospital with Nanjing Medical University
NCT03175224 RECRUITING APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Apollomics Inc.
NCT07040059 RECRUITING A Phase 1b/2 Clinical Trial Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma
Aurigene Discovery Technologies Limited
NCT06580002 RECRUITING Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
University of California, Irvine
NCT06239194 RECRUITING Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
ModeX Therapeutics, An OPKO Health Company
NCT07025889 RECRUITING IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer
Ruijin Hospital
NCT06766305 RECRUITING QL1706 Combined With SOX Used in Theperioperative Treatment
Xiangdong Cheng
NCT04118114 RECRUITING Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors
National Cancer Centre, Singapore
NCT04817826 ACTIVE NOT RECRUITING TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.
Gruppo Oncologico del Nord-Ovest
NCT03448835 ACTIVE NOT RECRUITING Neoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer (PANDA)
The Netherlands Cancer Institute
NCT05504720 ACTIVE NOT RECRUITING Evaluating Pembrolizumab, Trastuzumab and FLOT as Perioperative Treatment of HER2-positive, Localized Esophagogastric Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT04581473 ACTIVE NOT RECRUITING Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection
CARsgen Therapeutics Co., Ltd.
NCT06992024 ACTIVE NOT RECRUITING Electroacupuncture Combined With Paclitaxel Protein-bound and PD-1 Antibody for Second-line Treatment of HER2 Negative, pMMR/MSS Advanced Gastric Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT06199895 RECRUITING Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Liu Huang
NCT06998771 NOT YET RECRUITING JSKN003 Combined Treatment of HER2-positive Gastric Cancer
Shanghai JMT-Bio Inc.
NCT06157996 RECRUITING Lenvatinib Plus Tislelizumab and CapeOX as First-Line Treatment for Advanced GC/GEJC With Positive PD-L1 and Low TMEscore
Nanfang Hospital, Southern Medical University
NCT04923932 ACTIVE NOT RECRUITING Savolitinib for Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients
Hutchison Medipharma Limited
NCT04140526 ACTIVE NOT RECRUITING Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
OncoC4, Inc.
NCT06985602 RECRUITING Adebrelimab With Chemoradiotherapy and Surgery for G/GEJ
Jiangsu Cancer Institute & Hospital
NCT06340711 RECRUITING Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma
Weill Medical College of Cornell University
NCT04152499 ACTIVE NOT RECRUITING Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)
Klus Pharma Inc.
NCT06957977 NOT YET RECRUITING A Randomized Controlled Study of Endoscopic Cryoablation Combined With PD-1 Inhibitor for Maintenance Therapy in Advanced Gastric Cancer
Zhongguang Luo, MD
NCT06759233 NOT YET RECRUITING Endoscopic Cryoablation Combined With PD-1 in Advanced Gastric Cancer
Zhongguang Luo, MD
NCT06942767 NOT YET RECRUITING Combination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Qilu Pharmaceutical Co., Ltd.
NCT06940921 ACTIVE NOT RECRUITING SBRT-LDRT-Cadonilimab for Advanced Gastric, Colorectal and Ovarian Cancers With Peritoneal Metastases
Zhang Tao
NCT06942663 NOT YET RECRUITING Randomized Phase II Trial Evaluating DFS in The Absence of an Adjuvant Component of Perioperative Chemotherapy in Patients With Gastric Cancer
Nizhny Novgorod Regional Clinical Oncology Center
NCT06933966 NOT YET RECRUITING Evaluation of Efficacy and Safety De-escalation Versus Standard Adjuvant Chemotherapy in Patients With Low Risk Localized Gastroesophageal Adenocarcinoma
Centre Leon Berard
NCT06685887 RECRUITING A Clinical Study Evaluating the Efficacy of Systemic Chemotherapy and Immune Checkpoint Inhibitors Combined With Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer Patients With Peritoneal Metastasis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT04196465 ACTIVE NOT RECRUITING Phase II Study of Neoadjuvant Immune Checkpoint Inhibitor in Patients With Resectable Gastrointestinal Cancers
Asan Medical Center
NCT06914687 NOT YET RECRUITING Efficacy of Tirellizumab Combined With Oral, Intravenous and Abdominal Chemotherapy in Peritoneal Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma
Fudan University
NCT04166721 ACTIVE NOT RECRUITING WaKING: Wnt and checKpoint INhibition in Gastric Cancer
Royal Marsden NHS Foundation Trust
NCT06731803 RECRUITING Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT06888037 NOT YET RECRUITING Fruquintinib Combined With PD-1 Inhibitor as First-line Maintenance Therapy for Advanced Gastric Cancer
Ruijin Hospital
NCT06881017 NOT YET RECRUITING Establishment of Precision Targeted Therapy Strategies for Advanced Gastric Cancer Based on Novel Molecular Subtyping
China Medical University, China
NCT06871527 NOT YET RECRUITING Fruquintinib Combined With PD-1 Inhibitor and FOLFOX as First-Line Treatment For Advanced Gastric Cancer
Sixth Affiliated Hospital, Sun Yat-sen University
NCT05319639 RECRUITING Phase I/II Study of the Combination of Irinotecan and POF (POFI) and Tislelizumab
Fujian Cancer Hospital
NCT06405113 RECRUITING FMT+SOX+Sintilimab As First-line Treatment for Advanced Gastric Cancer
Changzhou No.2 People's Hospital
NCT04114136 RECRUITING Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
Dan Zandberg
NCT05586061 ACTIVE NOT RECRUITING First-line Treatment with RC48 Plus Tislelizumab and S-1(RCTS) in Advanced Gastric Cancer
Qilu Hospital of Shandong University
NCT03526835 RECRUITING A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Merus B.V.
NCT06791083 RECRUITING Clinical Study of Envafolimab Combined With Fruquintinib and Chemotherapy for Neoadjuvant Treatment of Gastric Cancer
First Affiliated Hospital of Fujian Medical University
NCT06791148 RECRUITING Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT06792162 RECRUITING PD-1 Antibody Carilizumab Combined with Apatinib for Unresectable Stage III and IV DMMR Gastric Cancer
Peking University Third Hospital
NCT04902872 ACTIVE NOT RECRUITING Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors
Cybrexa Therapeutics
NCT06776770 RECRUITING A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
NCT06422403 RECRUITING A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
National University Hospital, Singapore
NCT04404595 ACTIVE NOT RECRUITING Claudin18.2 CAR-T (CT041) in Patients with Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers
CARsgen Therapeutics Co., Ltd.
NCT03368963 ACTIVE NOT RECRUITING TAS102 in Combination With NAL-IRI in Advanced GI Cancers
Emory University
NCT06730373 RECRUITING First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)
Qilu Hospital of Shandong University
NCT06054906 RECRUITING Neoadjuvant of Sintilimab Combined Weekly Metronomic Chemotherapy (PLOF) for Resectable Locally Advanced Gastric Cancer
Huashan Hospital
NCT05572684 ACTIVE NOT RECRUITING A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectable or Metastatic Solid Tumors
NextCure, Inc.
NCT06730581 NOT YET RECRUITING Utidelone Capsule Monotherapy for Patients with Advanced Solid Tumors
Beijing Biostar Pharmaceuticals Co., Ltd.
NCT06711471 RECRUITING Trifluridine/tipiracil (TAS-102), Bevacizumab, and Camrelizumab As Third-line or Later-line Therapy of Gastric Cancer
LIN YANG
NCT06706895 NOT YET RECRUITING A Single-arm, Single-center Phase II Clinical Study on the Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection Combined With Fruquintinib Capsules in the Second-line Treatment of Patients With Advanced Gastric Cancer
Shanghai Zhongshan Hospital
NCT05640830 RECRUITING Trastuzumab, Bevacizumab with Paclitaxel for HER2-positive Gastric Cancer in a Second-line Therapy
Kangbuk Samsung Hospital
NCT03259867 RECRUITING Combination of TATE and PD-1 Inhibitor in Liver Cancer
Teclison Ltd.
NCT06697366 NOT YET RECRUITING Liposomal Irinotecan Combined with Sintilimab for Second-line Treatment of Progressive Gastric Cancer
Ruijin Hospital
NCT05034887 RECRUITING Phase 2 Study of Trastuzumab Deruxtecan in the Neoadjuvant Treatment, or Trastuzumab Deruxtecan Plus Capecitabine Plus Durvalumab(MEDI4736) in the Preoperative and Postoperative Adjuvant Treatment for Patients with HER2 Positive Gastric and Gastroesophageal Junction Adenocarcinoma
National Cancer Center Hospital East
NCT04745988 ACTIVE NOT RECRUITING An Open Label Phase 2 Study to Evaluate the Safety and Efficacy of Lenvatinib with Pembrolizumab or Lenvatinib, Pembrolizumab and FLOT in the Neoadjuvant / Adjuvant Treatment for Patients with Gastric Cancer
National Cancer Center Hospital East
NCT06532799 RECRUITING TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer
Essen Biotech
NCT06667050 ACTIVE NOT RECRUITING CAPOX Plus Sintilimab and Bevacizumab Biosimilar (IBI305) for Neoadjuvant Treatment of Locally Advanced Gastric Cancer
West China Hospital
NCT05476796 RECRUITING Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer
UNICANCER
NCT04492488 ACTIVE NOT RECRUITING A Study of MRG002 in Patients with HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer
Shanghai Miracogen Inc.
NCT05620134 ACTIVE NOT RECRUITING Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer
Salubris Biotherapeutics Inc
NCT06459921 NOT YET RECRUITING Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer
Xijing Hospital
NCT04913337 ACTIVE NOT RECRUITING Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
NGM Biopharmaceuticals, Inc
NCT04725994 RECRUITING Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination with XELOX or Irinotecan in Patients with Advanced Gastric Cancer
Idience Co., Ltd.
NCT04515615 ACTIVE NOT RECRUITING Adjuvant Chemotherapy in Combination With Camrelizumab for Stage III Gastric Cancer (FOCUS-02)
Yu jiren
NCT06586294 NOT YET RECRUITING A Study of Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma
Akeso
NCT06592287 NOT YET RECRUITING The Combination of Adebrelimab, Apatinib, and Lrinotecan Liposome for Second-line Treatment of Advanced Gastric Cancer
Xianglin Yuan
NCT05715931 RECRUITING Perioperative Chemotherapy Plus Trastuzumab Plus Toripalimab in HER2 Positive Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma
Yu jiren
NCT06577376 NOT YET RECRUITING A PhaseⅠ/Ⅱ Study of Simmitinib or Irinotecan Liposomes Combined With DP303c in Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma
Shanghai Runshi Pharmaceutical Technology Co., Ltd
NCT06580574 RECRUITING Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers
Peking University
NCT06572319 RECRUITING Disitamab Vedotin Plus Trastuzumab in Patients With HER2 Positive GC/GEJ Patiens
Zhejiang Cancer Hospital
NCT06560528 RECRUITING Disitamab Vedotin Combined With Tislelizumab and Capecitabine in the Perioperative Treatment of Locally Advanced Gastric Cancer With HER2 Overexpression
Tianjin Medical University Cancer Institute and Hospital
NCT06555471 RECRUITING A Single-arm, Phase II Exploratory Study of Sintilimab in Combination With Chemoradiotherapy in Elderly Patients With Locally Advanced Gastric Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT06551896 NOT YET RECRUITING Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06006390 RECRUITING CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT05177133 RECRUITING Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT06531291 NOT YET RECRUITING Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine Differentiation
RenJi Hospital
NCT06256328 ACTIVE NOT RECRUITING A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)
Ono Pharmaceutical Co. Ltd
NCT06496789 RECRUITING Neoadjuvant Serplulimab in Combination With Chemotherapy in Locally Advanced Gastric or Gastro-esophageal Junction Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT04278222 RECRUITING Anlotinib Plus Toripalimab as First-line Treatment for Advanced Gastric Cancer With ECOG 2 (APICAL-GC)
Shanghai Changzheng Hospital
NCT05771584 RECRUITING Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Gastric Cancer
Aston Sci. Inc.
NCT05739045 RECRUITING Nivolumab Combined With SOX Used in the Perioperative Treatment
Xiangdong Cheng
NCT06492317 NOT YET RECRUITING RC48 Plus AK104 as First-line Treatment for HER2-overexpressing Advanced Gastric Cancer
The First Affiliated Hospital of Zhengzhou University
NCT05394740 ACTIVE NOT RECRUITING Clinical Study of Regorafenib and Nivolumab Plus Chemotherapy
National Cancer Center Hospital East
NCT03760822 ACTIVE NOT RECRUITING Second-Line Chemotherapy With Ramucirumab +/- Paclitaxel in Elderly Advanced Gastric or Gastroesophageal Junction Cancer Patients
Federation Francophone de Cancerologie Digestive
NCT03959293 ACTIVE NOT RECRUITING Clinical Trial Evaluating FOLFIRI + Durvalumab vs FOLFIRI + Durvalumab and Tremelimumab in Second-line Treatment of Patients With Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma
Federation Francophone de Cancerologie Digestive
NCT06487429 RECRUITING Short Course Radiotherapy With Sequential Disitamab Vedotin Combined With S-1 and Sintilimab as Whole Course Neoadjuvant Therapy for HER2 Expressed Locally Progressive Gastric Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT06487715 ENROLLING BY INVITATION Safety and Efficacy of Systemic Chemotherapy Plus PD-1 Inhibitor in Combination With Bevacizumab in Gastric Cancer With Peritoneal Metastasis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT06196697 RECRUITING AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer
Harbin Medical University
NCT06475417 RECRUITING Neoadjuvant Adebrelimab + DOS in Locally Advanced Resectable Gastric Cancer
Tang-Du Hospital
NCT05187338 RECRUITING Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT06385691 RECRUITING Study Evaluating the Efficacy of the myDIET Software Tool in the Nutritional Management of Patients With Localized and Resectable Gastric or Esogastric Junction Cancer.
Centre Leon Berard
NCT06253650 RECRUITING Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease
Gruppo Oncologico del Nord-Ovest
NCT06454435 NOT YET RECRUITING Conversion Therapy of Sintilimab in Combination With Fruquintinib and Chemotherapy Versus Sintilimab and Chemotherpay in Stage IV Gastric Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT05269381 RECRUITING Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Mayo Clinic
NCT06451211 RECRUITING Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer
Sun Yat-sen University
NCT06447636 NOT YET RECRUITING Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma
Fudan University
NCT06439550 NOT YET RECRUITING Adjuvant Treatment With Serplulimab,Trastuzumab and SOX in the HER-2 Positive GC/GEJC
The First Affiliated Hospital of Zhengzhou University
NCT06437678 NOT YET RECRUITING Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer
Zhejiang Cancer Hospital
NCT06426654 NOT YET RECRUITING Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer
West China Hospital
NCT04799548 RECRUITING A Phase II Study of TACE Plus PD-1 Antibody in the Locally Advanced Stomach Adenocarcinoma
Shanghai Zhongshan Hospital
NCT06419140 NOT YET RECRUITING Multimodal Rehabilitation on Gastric Adenocarcinoma Patients Following Radical D2 Gastrectomy
Zhejiang Cancer Hospital
NCT06385873 NOT YET RECRUITING RC48 Combined With Adebrelimab, Apatinib and S-1 as Neoadjuvant Therapy in Locally Advanced Gastric Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT06023758 RECRUITING Phase 2 Trial of KN026+KN046±XELOX in HER2-positive Locally Advanced GC
Peking University
NCT02931890 ACTIVE NOT RECRUITING Multicentric Randomised Trial for Resectable Gastric Cancer
The Netherlands Cancer Institute
NCT06383559 RECRUITING Safety and Efficacy of XELOX Combined With Sintilimab and Lenvatinib in Advanced AFP-positive Gastric Cancer Patients
Tianjin Medical University Cancer Institute and Hospital
NCT06374888 NOT YET RECRUITING Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases
Convalife (Shanghai) Co., Ltd.
NCT03579784 ACTIVE NOT RECRUITING Biomarker-oriented Study of Durvalumab (MEDI4736) in Combination With Olaparib and Paclitaxel in Gastric Cancer
Do-Youn Oh
NCT06374901 NOT YET RECRUITING Tislelizumab Combined With Neoadjuvant Chemotherapy Used in the Perioperative Treatment.
Xiangdong Cheng
NCT06371586 RECRUITING Neo-Sequence 2:NCT Plus Anti-angiogenesis Therapy and Immunotherapy for LADGC
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06365008 RECRUITING Sintilimab Plus FOLFIRI as Salvage Therapy for Patients With Advanced Gastric Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT04908813 ACTIVE NOT RECRUITING Study of HLX22 in Combanition With Trastuzumab and Chemotherapy Versus Placebo in Combination With Trastuzumab and Chemotherapy for Treatment of Locally Advanced or Metastatic Gastric Cancer
Shanghai Henlius Biotech
NCT06349967 NOT YET RECRUITING Nab-paclitaxel Combined With Cadonilimab (AK104) for the Second-line Treatment of Advanced Gastric Cancer
West China Hospital
NCT06341595 RECRUITING Concurrent Chemoradiotherapy Combined With Sintilimab as Neoadjuvant Therapy for GC Patients With PALM
The First Affiliated Hospital with Nanjing Medical University
NCT04660760 RECRUITING Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer
Academic and Community Cancer Research United
NCT06339216 NOT YET RECRUITING A Clinical Study of Adebrelimab Combined With Apatinib and Paclitaxel in Patients With Advanced Gastric Cancer.
Chinese PLA General Hospital
NCT06202716 NOT YET RECRUITING Cadonilimab Plus CapeOX as First-Line Treatment for Advanced GC/GEJC With High TMEscore
Nanfang Hospital, Southern Medical University
NCT04840264 RECRUITING Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction
Sixth Affiliated Hospital, Sun Yat-sen University
NCT06310473 NOT YET RECRUITING Neoadjuvant Cadonilimab Plus Chemotherapy for Locally Advanced Esophagogastric Junction and Gastric Cancer Trial
Nanfang Hospital, Southern Medical University
NCT04249739 ACTIVE NOT RECRUITING Pembrolizumab + Capecitabine/Oxaliplatin (CapeOx) -HER2 Nagative and Pembrolizumab + Trastuzumab + Cisplatin/Capecitabine HER2 Positive
Samsung Medical Center
NCT05975749 RECRUITING Adjuvant Serplulimab and Trastuzuma and Chemotherapy in Her-2+ Gastric Cancer
Fudan University
NCT06036745 RECRUITING Exploratory Single-arm, Single-center Adjuvant Treatment of Stage IIIB-IIIC Gastric Cancer With Combination of Palizumab and SOX Regimen
Shanghai Minimally Invasive Surgery Center
NCT06295094 NOT YET RECRUITING The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients.
Odense University Hospital
NCT06283121 NOT YET RECRUITING A Clinical Study of BioTTT001 in Combination With SOX and Toripalimab in Patients With Gastric Cancer
China Medical University, China
NCT03950271 ACTIVE NOT RECRUITING SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine for Neoadjuvant Therapy of Gastric Adenocarcinoma/Gastroesophageal Junction Adenocarcinoma
Henan Cancer Hospital
NCT06266871 NOT YET RECRUITING SOX Combined With Tislelizumab and LDRT for Neoadjuvant Treatment of Locally Advanced Gastric Cancer
West China Hospital
NCT06241469 NOT YET RECRUITING Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction,a Phase II Clinical Study
Wu Jun
NCT06059495 RECRUITING Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study
GERCOR - Multidisciplinary Oncology Cooperative Group
NCT06238167 NOT YET RECRUITING Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC
First Affiliated Hospital of Wenzhou Medical University
NCT06222944 NOT YET RECRUITING Anlotinib, TQB2450 (PD-L1 Inhibitor), and Albumin-bound Paclitaxel Regimens in the Treatment of GC/GEJA
Peking University
NCT06213519 NOT YET RECRUITING HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis
Sichuan University
NCT06155383 RECRUITING Perioperative Disitamab Vedotin Plus Toripalimab and XELOX in Gastric or Gastroesophageal Junction Adenocarcinoma.
RemeGen Co., Ltd.
NCT06091423 RECRUITING XELOX Combined With Fruquintinib and Sintilimab Regimen Conversion Therapy for Gastric Cancer/Gastroesophageal Junction Adenocarcinoma Only With Liver and/or Retroperitoneal Lymph Node Metastasis, a Prospective Single-arm, Multicenter Study
Xiaofeng Chen
NCT06121700 RECRUITING Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
Fudan University
NCT05494060 RECRUITING XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University
NCT06118645 NOT YET RECRUITING Cadonilimab+ Paclitaxel (Albumin-bound) Treat Advanced Gastric Adenocarcinoma With PD-(L)1 Inhibitors Resistance
China Medical University, China
NCT06094868 NOT YET RECRUITING Clinical Study of Fruquintinib Combined With Sintilimab and XELOX Regimen in the Treatment of Advanced Cancer
Second Affiliated Hospital of Nanchang University
NCT05318794 NOT YET RECRUITING Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer
Imperial College London
NCT06008925 RECRUITING Clinical Study of VG161 Combined With Nivolumab Injection in Patients With Advanced Metastatic Gastric Cancer
CNBG-Virogin Biotech (Shanghai) Ltd.
NCT03488667 ACTIVE NOT RECRUITING Perioperative mFOLFOX Plus Pembrolizumab in Gastroesophageal Junction (GEJ) and Stomach Adenocarcinoma
University of Kansas Medical Center
NCT05687357 RECRUITING Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT05721651 RECRUITING Efficacy and Safety of Fruquintinib in Combination With PD-1 Inhibitors as First-line Maintenance Therapy for Advanced HER-2 Negative Gastric Cancer: a Single-arm, Prospective, Exploratory Clinical Study
Wu Jun
NCT05769725 RECRUITING A Study to Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer
RenJi Hospital
NCT05536102 RECRUITING The Effectiveness and Safety of XELOX and Tislelizumab + PLD for Resectable Gastric Cancer (LidingStudy)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
NCT04736485 ACTIVE NOT RECRUITING Perioperative Treatment in Resectable Gastric Cancer With Spartalizumab (PDR001) in Combination With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel (FLOT)
Centre Francois Baclesse
NCT05648487 NOT YET RECRUITING HIPEC Combined With Sintilimab for Gastric Cancer With Peritoneal Metastasis
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
NCT05618821 RECRUITING Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection for Remnant Gastric Cancer
Fujian Medical University
NCT05190445 ACTIVE NOT RECRUITING Cinrebafusp Alfa in Combination With Ramucirumab and Paclitaxel in HER2-High Gastric or GEJ Adenocarcinoma and in Combination With Tucatinib in HER2-Low Gastric or GEJ Andenocarinoma
Pieris Pharmaceuticals, Inc.
NCT05524974 NOT YET RECRUITING Clinical Study of Camrelizumab, Apatinib Mesylate and Nab-paclitaxel Combined With Oxplatin and S-1 in the Neoadjuvant Treatment of Locally Advanced Gastric Cancer With Different Genotypes
Fujian Medical University
NCT05439993 RECRUITING Tepotinib Plus Paclitaxel in MET Amplified or MET Exon 14 Alterated Gastric and GEJ Carcinoma
Hallym University Medical Center
NCT05000554 RECRUITING The Safety and Efficacy of PD-1 Monoantrapical Chemotherapy in the Treatment of Local Advanced Stomach Cancer
The First Hospital of Jilin University
NCT04973475 NOT YET RECRUITING Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer
Fujian Medical University
NCT04908566 RECRUITING Immune Checkpoint Inhibitor PD-1 Antibody Combined With Chemotherapy in the Perioperative Treatment of Locally Advanced Resectable Gastric or Gastroesophageal Junction Adenocarcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT03825861 RECRUITING Neoadjuvant FOLFIRINOX in the Treatment of Locally Advanced Gastric Cancer
Instituto do Cancer do Estado de São Paulo
NCT03686488 COMPLETED TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
H. Lee Moffitt Cancer Center and Research Institute
NCT05567835 TERMINATED A Study of Total Neoadjuvant Chemotherapy With FLOT VS Standard Perioperative FLOT in Patients With Gastric or GEJ Cancer
Baylor College of Medicine
NCT04426669 COMPLETED A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering
Intima Bioscience, Inc.
NCT03008278 COMPLETED Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT05070247 TERMINATED A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors
Takeda
NCT05641896 COMPLETED Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers
SOFIE
NCT04260802 TERMINATED A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
Ocellaris Pharma, Inc.
NCT06123468 COMPLETED Study Evaluating Treatment of Sacituzumab-govitecan for Patients With Metastatic Esophagogastric Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT05898854 COMPLETED [68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer
Aalborg University Hospital
NCT05419362 COMPLETED GEN-001 in Combination With Avelumab for Patients With PD-L1 Positive Gastric Cancer
Genome & Company
NCT03281369 COMPLETED A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)
Hoffmann-La Roche
NCT04798781 COMPLETED Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma
Andrew Hendifar, MD
NCT04779151 TERMINATED Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab
Gustave Roussy, Cancer Campus, Grand Paris
NCT05507658 COMPLETED Tislelizumab Combined With XELOX as Neoadjuvant Therapy for G/GEJ Adenocarcinoma
Xijing Hospital
NCT03797326 COMPLETED Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)
Merck Sharp & Dohme LLC
NCT04504916 TERMINATED A Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT03620643 COMPLETED Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours
Royal Marsden NHS Foundation Trust
NCT04208958 COMPLETED Study of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic Cancer
Vedanta Biosciences, Inc.
NCT04363801 TERMINATED A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer
Leap Therapeutics, Inc.
NCT04768686 COMPLETED FLX475 Combined With Pembrolizumab in Patients With Advanced or Metastatic Gastric Cancer
Hanmi Pharmaceutical Company Limited
NCT05104567 COMPLETED A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)
Sanofi
NCT05259696 COMPLETED Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)
Palleon Pharmaceuticals, Inc.
NCT05678205 WITHDRAWN A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors
Artiva Biotherapeutics, Inc.
NCT03636893 COMPLETED Dragon III: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer
Ruijin Hospital
NCT05714553 TERMINATED NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours
NuCana plc
NCT05563272 TERMINATED 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT04963088 COMPLETED Tislelizumab Combined With Anlotinib and Chemotherapy (XELOX) in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (TALENT)
The First Affiliated Hospital with Nanjing Medical University
NCT06812403 COMPLETED Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastrointestinal Endoscopy for Obese Patients
Zhejiang University
NCT02730546 COMPLETED Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery
Mayo Clinic
NCT05253053 COMPLETED To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT04727151 TERMINATED TAC T-cells for the Treatment of HER2-positive Solid Tumors
Triumvira Immunologics, Inc.
NCT04068896 COMPLETED Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
NGM Biopharmaceuticals, Inc
NCT06804876 COMPLETED COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients
Zhejiang University
NCT04383938 COMPLETED Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies
Aprea Therapeutics
NCT05311176 TERMINATED A Study of IMU-131 (HER-Vaxx) in Combination With Chemotherapy or Pembrolizumab in Patients With Metastatic HER2/Neu Over-Expressing Gastric Cancer (nextHERIZON)
Imugene Limited
NCT04579757 TERMINATED Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors
Hutchmed
NCT03609359 COMPLETED Lenvatinib and Pembrolizumab Simultaneous Combination Study
National Cancer Center Hospital East
NCT03064490 COMPLETED Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED)
Duke University
NCT03829501 TERMINATED A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies
Kymab Limited
NCT04195828 COMPLETED Camrelizumab Combined with Apatinib Mesylate Tablets, Nab-paclitaxel and S-1 in the Treatment of Locally Advanced Gastric Cancer
Fujian Medical University
NCT03724851 COMPLETED Vactosertib in Combination with Pembrolizumab in Metastatic Colorectal or Gastric Cancer
MedPacto, Inc.
NCT04976660 WITHDRAWN TT-4 As a Single Agent in Subjects with Advanced Selected Solid Tumors
Tarus Therapeutics, Inc.
NCT02689284 COMPLETED Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer
MacroGenics
NCT03627728 COMPLETED Study Maintenance Regorafenib vs Placebo, no Progression Patients After I Line Chemotherapy Metastatic Gastric Cancer
Gruppo Oncologico Italiano di Ricerca Clinica
NCT04510064 COMPLETED Conversion Effects of PD-1 Antibody Camrelizumab Combined With Nab-POF Regimen Chemotherpy in Patients With Initially Unresectable Locally Advanced or Limited Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma:FDZL-GC001 Trial
Fudan University
NCT04032704 TERMINATED A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors
Seagen Inc.
NCT04863430 WITHDRAWN Apatinib with Oxaliplatin and S-1 Treatment for Advanced Hepatoid Adenocarcinoma of the Stomach
Peking University
NCT05268510 COMPLETED Chemotherapy and Pembrolizumab, Followed by Pembrolizumab and Olaparib As Firstline Therapy in Her-2 Negative Gastric/GEJ Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT03092518 COMPLETED Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
National Cancer Institute (NCI)
NCT03662659 COMPLETED An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers
Bristol-Myers Squibb
NCT04034251 COMPLETED Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis
National Cancer Institute (NCI)
NCT02615730 COMPLETED PI3Kβ Selective Inhibitor With Paclitaxel, Advanced Gastric Adenocarcinoma
Yonsei University
NCT02485834 TERMINATED FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer
Alliance for Clinical Trials in Oncology
NCT04535414 COMPLETED Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers
National Cancer Institute (NCI)
NCT04162665 TERMINATED Pre-operative Adaptive Short Court Radiation Therapy in Gastric Cancer
Washington University School of Medicine
NCT03814759 COMPLETED Preoperative Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma
Yonsei University
NCT05500508 TERMINATED Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Aminex Therapeutics, Inc.
NCT03878472 COMPLETED Neoadjuvant Immunotherapy for Resectable Gastric Cancer
Qilu Hospital of Shandong University
NCT05555251 TERMINATED BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors
BioInvent International AB
NCT03698825 COMPLETED TEW-7197 with Paclitaxel for the Treatment of Metastatic Gastric Cancer
MedPacto, Inc.
NCT04276493 COMPLETED Anti-HER2 Bispecific Antibody Zanidatamab (ZW25) Activity in Combination With Chemotherapy With/Without Tislelizumab
BeiGene
NCT04508140 TERMINATED Study of BO-112 With Pembrolizumab for Colorectal or Gastric/GEJ Cancer With Liver Metastasis
Highlight Therapeutics
NCT04933227 TERMINATED A Study to Explore the Efficacy and Safety of Atezolizumab Plus Tiragolumab and Chemotherapy in 1st Line HER2 Negative Unresectable, Recurrent or Metastatic Gastric Cancer or Adenocarcinoma of Gastroesophageal Junction (GEJ)
Hoffmann-La Roche
NCT04937738 TERMINATED Perioperative Chemotherapy in Gastric Cancer
Ukrainian Society of Clinical Oncology
NCT04294784 TERMINATED Nab-paclitaxel Plus PD-1 Inhibitor Versus Nab-paclitaxel As Second-line Treatment in Advanced Gastric Cancer
Huazhong University of Science and Technology
NCT04871204 COMPLETED Octreotide Treatment to Improve Nutritional Recovery After Surgery for Patients with Esophageal or Gastric Cancer
Fredrik Klevebro
NCT03427814 COMPLETED Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer
BeiGene
NCT05012397 TERMINATED Milademetan in Advanced/Metastatic Solid Tumors
Rain Oncology Inc
NCT02794428 COMPLETED Chemoprevention of Gastric Carcinogenesis
Vanderbilt-Ingram Cancer Center
NCT04683939 TERMINATED Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors
BioNTech SE
NCT03453164 COMPLETED Checkpoint Inhibitor and Radiotherapy for Recurrent Gastric Cancer (CIRCUIT)
Fukushima Medical University
NCT02891447 COMPLETED Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer
M.D. Anderson Cancer Center
NCT04065139 COMPLETED Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Gastric Carcinomatosis. Phase II Randomized Study
Assistance Publique - Hôpitaux de Paris
NCT06206278 TERMINATED Evaluation of Infigratinib in Patients With Locally Advanced or Metastatic Gastric Cancer or GEJ Adenocarcinoma
LianBio LLC
NCT03852251 COMPLETED A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody, for Advanced Solid Tumors or With mXELOX/XELOX as First-line Therapy for Advanced Gastric or GEJ Adenocarcinoma
Akeso
NCT04931420 WITHDRAWN Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
University of Chicago
NCT04408599 TERMINATED A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors
NextCure, Inc.
NCT03141034 COMPLETED Ramucirumab Plus Irinotecan for Previously Treated Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma
Washington University School of Medicine
NCT03921021 COMPLETED Phase 2 Study of Telomelysin (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma
Weill Medical College of Cornell University
NCT03382600 COMPLETED Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With TS-1+Cisplatin or TS-1+Oxaliplatin as First Line Chemotherapy in Gastric Cancer (MK-3475-659/KEYNOTE-659)
Merck Sharp & Dohme LLC
NCT03840967 TERMINATED A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma
Shadia Jalal, MD
NCT04089904 TERMINATED Phase II Trial of Neoadjuvant Pembrolizumab for Patients With Early Stage Gastroesophageal Adenocarcinoma
University of Chicago
NCT05529667 COMPLETED Fibroblast Growth Factor (FGFs) / Fibroblast Growth Factor Receptor (FGFRs) Genetic as a Second-line Therapy for Recurrent / Progressive Gastric Cancer With INCB054828 and Paclitaxel a Study to Evaluate the Safety and Efficacy of Combination Therapy.
Yonsei University
NCT04835896 COMPLETED Study of M7824 and Paclitaxel Combination as a Second-line Treatment in Patients With Recurrent/Metastatic Gastric Cancer
Yonsei University
NCT04742959 COMPLETED Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT04604132 TERMINATED Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
Basilea Pharmaceutica
NCT05687617 TERMINATED Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Laval University
NCT03321630 COMPLETED A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies
NYU Langone Health
NCT04547153 COMPLETED Infusional Fluorouracil and Weekly Docetaxel for Gastric Cancer With Bone Marrow Involvement and DIC
Sixth Affiliated Hospital, Sun Yat-sen University
NCT03342937 COMPLETED KeyLargo: Pembrolizumab + Oxaliplatin + Capecitabine in Gastric Cancer
Duke University
NCT05101616 SUSPENDED A Pilot Study of Neoadjuvant Chemotherapy With or Without Camrelizumab for Locally Advanced Gastric Cancer
Shanghai Minimally Invasive Surgery Center
NCT03694522 COMPLETED A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer
Five Prime Therapeutics, Inc.
NCT03751761 COMPLETED GC 2nd Line Durvalumab(MEDI4736)/Tremelimumab Plus Paclitaxel Study
Asan Medical Center
NCT05703555 WITHDRAWN INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701
Erasmus Medical Center
NCT02830594 COMPLETED Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer
City of Hope Medical Center
NCT02918162 COMPLETED Perioperative Chemo and Pembrolizumab in Gastric Cancer
Gulam Manji
NCT03283761 COMPLETED FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma
Al B. Benson, III, MD
NCT06238752 COMPLETED First-line Apatinib Combined With Tislelizumab and Chemotherapy for Advanced GC
Renmin Hospital of Wuhan University
NCT04770623 COMPLETED Docetaxel and Irinotecan in Gastric Cancer
Menoufia University
NCT03196232 COMPLETED Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric Cancer
George Albert Fisher
NCT03472365 COMPLETED A Study of SHR-1210 in Combination With Capecitabine + Oxaliplatin or Apatinib in Treatment of Advanced Gastric Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT03783936 COMPLETED Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas
Ashwin Somasundaram
NCT05363605 TERMINATED A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours
Fusion Pharmaceuticals Inc.
NCT03618758 COMPLETED Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6
Seoul National University Bundang Hospital
NCT02599324 COMPLETED Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors
Pharmacyclics LLC.
NCT05400915 COMPLETED Two-Part, Phase Ib/II, Open Label, Single-Arm, Multi-center Study to Evaluate the Safety and Efficacy of Varlitinib in Combination With Weekly Paclitaxel in EGFR/HER2 Co-expressing Advanced or Metastatic Gastric Cancer Patients
Yonsei University
NCT06090318 WITHDRAWN Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss
Rain Oncology Inc
NCT02995850 COMPLETED A Phase Ib/II Study of Efficacy and Feasibility of Cytoreductive Surgery, Extensive Peritoneal Lavage, Hyperthermicintraperitoneal Chemotherapy and Post-operative Intraperitoneal Chemotherapy Combination in Gastric Cancer With Peritoneal Metastasis
Yonsei University
NCT03602079 COMPLETED Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Klus Pharma Inc.
NCT03576131 TERMINATED GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors
Genmab
NCT05512182 WITHDRAWN Efficacy of Triplet Combination With Pembrolizumab, Neratinib, and Paclitaxel as a Second Line Treatment in Recurrent/Advanced Gastric Cancer Having Somatic Human Epidermal Growth Factor Receptor Family (EGFR, HER2, HER3, HER4) Mutations or HER2 Amplification/Overexpression
Yonsei University
NCT05411679 WITHDRAWN EP0057 in Combination With Olaparib in Relapsed Advanced Gastric Cancer and Small Cell Lung Cancer
Ellipses Pharma
NCT02935634 COMPLETED A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer
Bristol-Myers Squibb
NCT02344810 WITHDRAWN C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer
Eastern Cooperative Oncology Group
NCT02589496 COMPLETED Study of Pembrolizumab in Subjects With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Who Progressed After First-Line Therapy With Platinum and Fluoropyrimidine: Integration of Molecular Subtypes Through Integrative Genomic Analysis
Samsung Medical Center
NCT02489214 TERMINATED Donafenib Monotherapy for Previously Treated Metastatic Gastric Cancer
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NCT03918499 COMPLETED IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer
City of Hope Medical Center
NCT02954536 COMPLETED Phase II Trial of Pembrolizumab With Trastuzumab and Chemotherapy in Advanced HER2 Positive Esophagogastric (EG) Cancer
Memorial Sloan Kettering Cancer Center
NCT02983045 COMPLETED A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors
Nektar Therapeutics
NCT04099641 COMPLETED An Open Label Study of Bavituximab and Pembrolizumab in Advanced Gastric and GEJ Cancer Patients
OncXerna Theraputics, Inc.
NCT05135845 SUSPENDED Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma
Assistance Publique - Hôpitaux de Paris
NCT04510285 TERMINATED A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection
Memorial Sloan Kettering Cancer Center
NCT02501603 COMPLETED Afatinib, Paclitaxel, 2nd Line, Advanced Gastric Cancer
Yonsei University
NCT05025033 COMPLETED Chemotherapy Combined With Apatinib and PD-1 Antibody
Tianjin Medical University Cancer Institute and Hospital
NCT04168931 TERMINATED Trastuzumab to Patients With Advanced Gastric Cancer With HER2 Positive Expression in CTC
AC Camargo Cancer Center
NCT02393248 TERMINATED Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)
Incyte Corporation
NCT02191566 TERMINATED S-1/Oxaliplatin for High Risk Patients Who Underwent Gastrectomy
Kangbuk Samsung Hospital
NCT03755440 COMPLETED PD-1 Antibody in EBV Positive Metastatic Gastric Cancer Patients.
Sun Yat-sen University
NCT05535569 COMPLETED Phase Ib/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With Paclitaxel in Epstein-Barr Virus(EBV)-Related, or Microsatellite Instability-High (MSI-H), or Programmed Cell Death Ligand 1 (PD-L1) Positive Advanced Gastric Cancer
Yonsei University
NCT05091528 TERMINATED A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers
Silverback Therapeutics
NCT02725424 COMPLETED Optimizing the Strategy for Preoperative Chemotherapy in Locally Advanced Gastric/Gastroesophageal Cancer
Chinese Academy of Medical Sciences
NCT02335411 COMPLETED A Study of Pembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059)
Merck Sharp & Dohme LLC
NCT02447406 COMPLETED Phase Ib, Single-arm Study of AZD6094 (Volitinib) in Combination With Docetaxel, in Any Solid Cancer and Sequential Phase II, Single-arm Study of AZD6094 (Volitinib) in Combination With Docetaxel in Advanced Gastric Adenocarcinoma Patients With MET Amplification as a Second Line Treatment
Samsung Medical Center
NCT02449551 COMPLETED Study of AZD6094 (Volitinib) in Advanced Gastric Adenocarcinoma Patients With MET Amplification as a Third-line Treatment
Samsung Medical Center
NCT02448329 COMPLETED Study of AZD1775 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring TP53 Mutation as a Second-line Chemotherapy
Samsung Medical Center
NCT03365791 COMPLETED PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies
Novartis Pharmaceuticals
NCT03409848 COMPLETED Ipilimumab or FOLFOX in Combination With Nivolumab and Trastuzumab in HER2 Positive EsophagoGastric Adenocarcinoma
AIO-Studien-gGmbH
NCT03707028 TERMINATED A Study to Evaluate Safety, Tolerability, and Efficacy Profile of Rivoceranib With Paclitaxel in Advanced Gastric or Gastroesophageal Junction Cancer
Elevar Therapeutics
NCT03104283 COMPLETED Apatinib for the Elderly Advanced Gastric Cancer
Affiliated Hospital of Qinghai University
NCT02539225 COMPLETED A Study of Ramucirumab in Participants With Gastric or Gastroesophageal Junction Adenocarcinoma
Eli Lilly and Company
NCT05181865 WITHDRAWN Phase 1/2a Study to Evaluate FL-301 in Patients With Advanced Solid Tumors
Flame Biosciences
NCT03556345 COMPLETED A Study of RC48-ADC in Local Advanced or Metastatic Gastric Cancer Subjects With the Overexpression of HER2
RemeGen Co., Ltd.
NCT04105062 WITHDRAWN LS301 Uptake in Tumors of Patients Undergoing Liver, Pancreas, or Gastric Surgery
Washington University School of Medicine
NCT03342417 TERMINATED Combination of Nivolumab and Ipilimumab in Breast, Ovarian and Gastric Cancer Patients
ExcellaBio LLC
NCT03648879 COMPLETED Confocal Endoscopic Microscopy for Detection of Early Stage Gastric Cancer in Subjects With Hereditary Diffuse Gastric Cancer Syndrome
National Cancer Institute (NCI)
NCT04464967 WITHDRAWN Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers
NKGen Biotech, Inc.
NCT03083613 COMPLETED Raltitrexed and Paclitaxel for Gastric or Gastroesophageal Junction Adenocarcinoma
Chinese Academy of Medical Sciences
NCT02628951 COMPLETED Ramucirumab/Paclitaxel as Second-line Treatment in Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma With Integrative Genomic Analysis
Samsung Medical Center
NCT04338438 COMPLETED Efficacy and Safety of Apatinib Combined With S-1 for Patients With Advance Gastric Cancer
Beijing Friendship Hospital
NCT03554395 WITHDRAWN Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Gastric Cancer
Fuda Cancer Hospital, Guangzhou
NCT02864381 COMPLETED Study to Evaluate the Efficacy and Safety of Andecaliximab Combined With Nivolumab Versus Nivolumab Alone in Adults With Unresectable or Recurrent Gastric or Gastroesophageal Junction Adenocarcinoma
Gilead Sciences
NCT02443883 COMPLETED A Phase 2 Study of Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Junction (GEJ) Cancer
Eli Lilly and Company
NCT02514551 COMPLETED A Study of Ramucirumab (LY3009806) in Combination With Paclitaxel in Participants With Gastric Cancer
Eli Lilly and Company
NCT03704077 WITHDRAWN An Investigational Immuno-therapy Study of Relatlimab Plus Nivolumab Compared to Various Standard-of-Care Therapies in Previously Treated Participants With Recurrent, Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
Bristol-Myers Squibb
NCT03739801 WITHDRAWN MM-398 and Ramucirumab in Treating Patients With Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
University of Southern California
NCT03606928 COMPLETED mFLOT Chemotherapy as First-line Treatment in GC
Ruijin Hospital
NCT02713984 WITHDRAWN A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer
Zhi Yang
NCT02726399 TERMINATED Phase II Study of Ramucirumab With Chemotherapy in Patients With Metastatic Gastroesophageal Junction and Gastric Cancer
Memorial Sloan Kettering Cancer Center
NCT02451956 COMPLETED Study of AZD5363 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring PIK3CA Mutation and/or PIK3CA Amplification as a Second-line Chemotherapy
Samsung Medical Center
NCT02447380 COMPLETED Study of AZD6094 (Volitinib) in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With MET Overexpression as a Second-line Treatment
Samsung Medical Center
NCT03766607 WITHDRAWN Trastuzumab Beyond Progression in HER2 Positive Metastatic Gastric Cancer
Korean South West Oncology Group
NCT02999295 COMPLETED A Phase 1/2 Study of Ramucirumab Plus Nivolumab in Participants With Gastric or GEJ Cancer
National Cancer Center, Japan
NCT02449655 TERMINATED Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53/MET) Gastric Adenocarcinoma Patients as Second-line Chemotherapy
Samsung Medical Center
NCT03150628 TERMINATED Cytoreductive Surgery and Intraperitoneal Chemotherapy for Stomach CAncer: a Feasibility Study
Richard van Hillegersberg
NCT03122548 TERMINATED Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal Cancers
Aduro Biotech, Inc.
NCT02216149 TERMINATED Effects of S-1 and Capecitabine on Coronary Artery Blood Flow
Heikki Joensuu
NCT02943603 WITHDRAWN A Study of Perioperative mFOLFOX6 Plus Pembrolizumab in Patients With Potentially Resectable Adenocarcinoma of the Gastroesophageal Junction (GEJ) and Stomach
Weijing Sun, MD, FACP
NCT02638909 TERMINATED Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies
Criterium, Inc.
NCT02856867 WITHDRAWN Nintedanib Plus mFOLFOX6 for Previously Untreated Metastatic Esophagogastric Adenocarcinoma (MEGAN)
European Organisation for Research and Treatment of Cancer - EORTC
NCT01946061 TERMINATED A Phase II Trial of Adjuvant Chemotherapy With S-1 Plus Oxaliplatin for Locally Advanced Gastric Cancer
Yonsei University
NCT02296671 WITHDRAWN Personalized Therapy for Esophagogastric Cancer Using Thymidylate Synthase Genetic Markers
Washington University School of Medicine
NCT02347956 COMPLETED The Safety and Feasibility of Reduced Port Robotic Distal Gastrectomy Using Single-site for Surgical Treatment of Early Gastric Cancer
Yonsei University