TheraRadar

Pharma Intelligence, Simplified

Landscape Gastrointestinal

Constipation

130 clinical trials

40 active
/
130 total (since 2015)
8
Phase 1 Active
17 total
20
Phase 2 Active
58 total
11
Phase 3 Active
40 total
11
Phase 4 Active
32 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Ardelyx 4 3 0
Shionogi 1 0 0
HK inno.N Corporation 1 0 0
Braintree Laboratories 0 6 0
AbbVie 0 5 0
Takeda 0 3 1
Bausch Health Americas, Inc. 0 3 0
Enterin Inc. 0 2 1
Ironwood Pharmaceuticals, Inc. 0 2 1
Forest Laboratories 0 2 1
KGK Science Inc. 0 3 0
NCT07382167 RECRUITING
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Ardelyx n=692
NCT07277907 RECRUITING
Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation
Third Military Medical University n=346
NCT05905926 ENROLLING BY INVITATION
Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C
Ardelyx n=150
NCT05643534 RECRUITING
Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years
Ardelyx n=180
NCT05519683 RECRUITING
Home Transcutaneous Electrical Acustimulation (TEA)
University of Michigan n=160
NCT04547816 RECRUITING
Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse
Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology n=100
NCT06810167 RECRUITING
Assessing Tenapanor as a Treatment of CF-related Constipation.
Massachusetts General Hospital n=25
NCT06836024 NOT YET RECRUITING
A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation
Hamilton Health Sciences Corporation n=60
NCT06740422 NOT YET RECRUITING
Xuanhuang Runtong Tablet in the Treatment of Constipation (Yin-deficiency Type)
Beijing Hospital of Traditional Chinese Medicine n=300
NCT06413368 NOT YET RECRUITING
Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study
Children's Hospital Los Angeles n=20
NCT06351995 ACTIVE NOT RECRUITING
Neostigmine and Glycopyrrolate by Iontophoresis
James J. Peters Veterans Affairs Medical Center n=6
NCT04166058 COMPLETED
Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
AbbVie n=381
NCT05652205 COMPLETED
A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
AbbVie n=123
NCT04026113 COMPLETED
Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
AbbVie n=438
NCT02809105 COMPLETED
A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation
Astellas Pharma Inc n=186
NCT05151328 COMPLETED
Efficacy and Safety of Plecanatide Comparing With Placebo in the Treatment of Functional Constipation
Shandong Luoxin Pharmaceutical Group Stock Co., Ltd. n=648
NCT04759833 TERMINATED
A Study of Prucalopride For Functional Constipation in Children and Teenagers
Takeda n=175
NCT02822508 COMPLETED
A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation
Braintree Laboratories n=434
NCT05341180 COMPLETED
Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial
All India Institute of Medical Sciences, Bhubaneswar n=144
NCT04433390 COMPLETED
Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery
CMC Ambroise Paré n=305
NCT02705378 WITHDRAWN
The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit
Massachusetts General Hospital
NCT03573908 COMPLETED
A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Ironwood Pharmaceuticals, Inc. n=614
NCT02727751 COMPLETED
A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C
Ardelyx n=312
NCT02481947 COMPLETED
A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
Braintree Laboratories n=459
NCT02819297 COMPLETED
BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
Braintree Laboratories n=1,020
NCT02819310 COMPLETED
An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults
Braintree Laboratories n=330
NCT04451096 COMPLETED
Probiotics-prebiotic Fiber Therapy in Parkinson's Disease Patients With Constipation
National University of Malaysia n=48
NCT02766777 COMPLETED
Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation
Sucampo Pharma Americas, LLC n=87
NCT02686138 COMPLETED
A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
Ardelyx n=593
NCT02621892 COMPLETED
A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C
Ardelyx n=606
NCT03097861 COMPLETED
Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo
Sucampo Pharma Americas, LLC n=552
NCT02493452 COMPLETED
Second Plecanatide Study In Irritable Bowel Syndrome With Constipation (IBS-C)
Bausch Health Americas, Inc. n=1,135
NCT02729909 COMPLETED
Lubiprostone for Chronic Idiopathic Constipation Treatment
Takeda n=211
NCT03885973 COMPLETED
Lactobacillus Plantarum IS 10560 Supplementation in Women With Functional Constipation
Fakultas Kedokteran Universitas Indonesia n=76
NCT03829358 COMPLETED
The Role of Probiotics in Improving Quality of Life in Women With Functional Constipation
Fakultas Kedokteran Universitas Indonesia n=76
NCT02695719 COMPLETED
Lubiprostone for Treatment of Chronic Idiopathic Constipation
Takeda n=156
NCT02651155 COMPLETED
Lubiprostone for the Treatment of Chronic Idiopathic Constipation
Takeda n=204
NCT02961556 COMPLETED
General Clinical Study of AJG555 in Pediatric Patients With Chronic Constipation
EA Pharma Co., Ltd. n=39
NCT03100851 COMPLETED
Effect of Probiotic on Constipation
China Agricultural University n=62
NCT02292459 WITHDRAWN
Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005)
Bayer