TheraRadar

Pharma Intelligence, Simplified

Landscape Oncology

Cholangiocarcinoma

468 clinical trials

258 active
/
468 total (since 2015)
78
Phase 1 Active
146 total
192
Phase 2 Active
348 total
28
Phase 3 Active
45 total
4
Phase 4 Active
4 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
AstraZeneca 8 2 0
Eli Lilly 3 2 1
TransThera Sciences (Nanjing), Inc. 3 3 0
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 3 0 0
NGM Biopharmaceuticals, Inc 3 0 0
Chongqing Precision Biotech Co., Ltd 3 0 0
Merck 2 2 0
InnoPharmax Inc. 2 1 0
Akeso 2 0 0
SystImmune Inc. 2 0 0
TCR2 Therapeutics 2 0 0
Roche 1 2 1
Jiangsu HengRui Medicine Co., Ltd. 1 0 2
Seagen, a wholly owned subsidiary of Pfizer 1 0 1
Jazz Pharmaceuticals 1 1 0
NCT06109779 ACTIVE NOT RECRUITING
Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)
AstraZeneca n=757
NCT07437287 NOT YET RECRUITING
Testing Mitazalimab in Combination With Standard Chemotherapy in Immunotherapy Resistant Advanced Biliary Tract Cancers
UNICANCER n=160
NCT06282575 RECRUITING
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
Jazz Pharmaceuticals n=286
NCT05771480 ACTIVE NOT RECRUITING
Durvalumab With Chemotherapy as First Line Treatment in Patients With Advanced Biliary Tract Cancers (aBTCs)
AstraZeneca n=142
NCT05876754 RECRUITING
An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma
Servier Affaires Médicales n=220
NCT06467357 RECRUITING
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
AstraZeneca n=620
NCT07221253 RECRUITING
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
AstraZeneca n=1,100
NCT07229625 RECRUITING
A Phase III Study of SHR-8068 in Combination With Adebrelimab and Platinum-Containing Chemotherapy Versus Durvalumab in Combination With Platinum-Containing Chemotherapy as First-line Treatment for Advanced Biliary Tract Cancer (BTC)
Suzhou Suncadia Biopharmaceuticals Co., Ltd. n=604
NCT07265674 RECRUITING
A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer
J-Pharma Co., Ltd. n=480
NCT06591520 ACTIVE NOT RECRUITING
AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer
Akeso n=682
NCT07328919 NOT YET RECRUITING
Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations
TransThera Sciences (Nanjing), Inc. n=138
NCT04353375 RECRUITING
HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma
Hutchmed n=235
NCT06851663 RECRUITING
Trop2-targeted immunoPET Imaging of Solid Tumors
RenJi Hospital n=400
NCT07155525 RECRUITING
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
Minia University n=194
NCT04669496 ACTIVE NOT RECRUITING
Phase II-III Clinical Trial of PD1 Antibody (Toripalimab), Lenvatinib and GEMOX Neoadjuvant Treatment for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors
Shanghai Zhongshan Hospital n=178
NCT07062263 RECRUITING
Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients
Tata Memorial Centre n=220
NCT06622057 NOT YET RECRUITING
D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer
InnoPharmax Inc. n=195
NCT05065957 RECRUITING
Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer
InnoPharmax Inc. n=180
NCT05342194 RECRUITING
Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study
Shanghai Junshi Bioscience Co., Ltd. n=480
NCT05506943 ACTIVE NOT RECRUITING
A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)
Compass Therapeutics n=150
NCT06355427 RECRUITING
The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal Cholangiocarcinoma
Mara Veenstra, MD n=81
NCT06923475 NOT YET RECRUITING
Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal Cholangiocarcinoma
Amsterdam UMC, location VUmc n=150
NCT06037980 RECRUITING
CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence
Gruppo Oncologico del Nord-Ovest n=300
NCT05823311 RECRUITING
Lenvatinib, Tislelizumab Combined with Gemcitabine and Cisplatin (GPLET) in the Treatment of Advanced Cholangiocarcinoma
Second Affiliated Hospital, School of Medicine, Zhejiang University n=80
NCT06671418 ENROLLING BY INVITATION
Primary Percutaneous Stenting Above the Ampulla Versus Endoscopic Drainage for Unresectable Malignant Hilar Biliary Obstruction
Erasmus Medical Center n=148
NCT06662877 NOT YET RECRUITING
Anlotinib Plus Nab-Paclitaxels and S-1 for Patients with Advanced Biliary Tract Cancer As Second-Line Treatment
Sun Yat-sen University n=206
NCT05948475 RECRUITING
Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma
TransThera Sciences (Nanjing), Inc. n=200
NCT05429697 RECRUITING
Study of SMT-NK Inj. Plus Pembrolizumab vs Pembrolizumab Monotherapy in Patients With Advanced Biliary Tract Cancer
SMT bio Co., Ltd. n=128
NCT03768414 COMPLETED
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers
SWOG Cancer Research Network n=452
NCT04157985 COMPLETED
Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors
Dan Zandberg n=161
NCT03656536 TERMINATED
A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma
Incyte Corporation n=167
NCT02807181 TERMINATED
SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma
Sirtex Medical n=89
NCT05924880 COMPLETED
A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC)
AstraZeneca n=116
NCT02349412 COMPLETED
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
Alliance for Clinical Trials in Oncology n=405
NCT04093362 TERMINATED
Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements
Taiho Oncology, Inc. n=10
NCT03673072 COMPLETED
Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTC
Krankenhaus Nordwest n=68
NCT02989857 COMPLETED
Study of AG-120 in Previously Treated Advanced Cholangiocarcinoma With IDH1 Mutations (ClarIDHy)
Institut de Recherches Internationales Servier n=187
NCT03773302 TERMINATED
Phase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/Translocations
QED Therapeutics, a BridgeBio company n=48
NCT04066491 TERMINATED
Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC
EMD Serono Research & Development Institute, Inc. n=309
NCT04163900 TERMINATED
Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer
NuCana plc n=773
NCT02853474 COMPLETED
Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy
Centre Oscar Lambret n=480
NCT02591030 COMPLETED
Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct Tumours
Centre Hospitalier Universitaire de Saint Etienne n=191
NCT03093870 COMPLETED
Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer
ASLAN Pharmaceuticals n=151
NCT02597465 WITHDRAWN
A Randomized, Open-Label, Comparative, Parallel-Group, Multicenter Study of SPARC1507
Sun Pharma Advanced Research Company Limited
NCT03081039 WITHDRAWN
A Study of Cisplatin or Carboplatin With Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Patients With Resected or Ablation Intra-Hepatic Cholangiocarcinoma
University of Louisville