NCT04345913 ACTIVE NOT RECRUITING Testing the Addition of Copanlisib to Eribulin in Metastatic Triple Negative Breast Cancer
National Cancer Institute (NCI)
NCT04550494 RECRUITING Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
National Cancer Institute (NCI)
NCT04090398 ACTIVE NOT RECRUITING Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones
National Cancer Institute (NCI)
NCT03606967 RECRUITING Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
National Cancer Institute (NCI)
NCT06324357 RECRUITING Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Boehringer Ingelheim
NCT02465060 ACTIVE NOT RECRUITING Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
National Cancer Institute (NCI)
NCT06184750 RECRUITING Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
National Cancer Institute (NCI)
NCT06966453 RECRUITING A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Pfizer
NCT03386617 ACTIVE NOT RECRUITING AKY15-HK-301_NEPA Study
Chinese University of Hong Kong
NCT05564377 RECRUITING Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
National Cancer Institute (NCI)
NCT06268665 RECRUITING Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
University of California, Davis
NCT06195306 RECRUITING Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
National Cancer Institute (NCI)
NCT02398773 ACTIVE NOT RECRUITING FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapy
National Cancer Institute (NCI)
NCT05941520 RECRUITING Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
National Cancer Institute (NCI)
NCT07276880 NOT YET RECRUITING Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer
UNC Lineberger Comprehensive Cancer Center
NCT05180474 ACTIVE NOT RECRUITING GEN1047 for Solid Tumors - First in Human (FIH) Trial
Genmab
NCT07446452 RECRUITING Disitamab Vedotin Plus Bevacizumab in HER2-Low Metastatic Breast Cancer After T-DXd Failure: A Phase II Study
The First Affiliated Hospital with Nanjing Medical University
NCT07447050 RECRUITING Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
University of California, Irvine
NCT07069595 RECRUITING PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
UNC Lineberger Comprehensive Cancer Center
NCT06806930 RECRUITING Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)
George Washington University
NCT05579366 RECRUITING Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Genmab
NCT06956690 RECRUITING A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
Hummingbird Bioscience
NCT06679036 RECRUITING A Trial of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Breast Cancer Patients
Shandong Suncadia Medicine Co., Ltd.
NCT07441889 NOT YET RECRUITING HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)
University of Virginia
NCT06486883 RECRUITING Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype
MedSIR
NCT07443943 NOT YET RECRUITING A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial
University of Michigan Rogel Cancer Center
NCT04266249 ACTIVE NOT RECRUITING CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy
ECOG-ACRIN Cancer Research Group
NCT04771520 RECRUITING Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
M.D. Anderson Cancer Center
NCT05710328 ACTIVE NOT RECRUITING Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial
ECOG-ACRIN Cancer Research Group
NCT07389733 NOT YET RECRUITING A Study of HRS-6208 in Combination With HRS-8080, or Fulvestrant, or Letrozole, With or Without HRS-6209 in Patients With Advanced Unresectable or Metastatic Breast Cancer
Shandong Suncadia Medicine Co., Ltd.
NCT05768139 RECRUITING First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT06434064 RECRUITING Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer
Roswell Park Cancer Institute
NCT07441486 NOT YET RECRUITING A Single-arm, Prospective, Phase II Clinical Study of the Combination of Entinostat and Oral Paclitaxel in the Treatment of HR+HER2- Advanced Breast Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT06502691 RECRUITING [18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer
University of Washington
NCT06750484 RECRUITING Trial of Trastuzumab Deruxtecan in Previously Treated HER2
Yale University
NCT07109726 RECRUITING A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
Terremoto Biosciences Inc.
NCT07053085 RECRUITING A Study of Surgery and Radiotherapy in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT07421141 ACTIVE NOT RECRUITING De-escalation of Neoadjuvant Treatment (Paclitaxel + HP) in Early HER2+ Breast Cancer
National Medical Research Radiological Centre of the Ministry of Health of Russia
NCT03272334 ACTIVE NOT RECRUITING Her2-BATS and Pembrolizumab in Metastatic Breast Cancer
University of Virginia
NCT04468061 RECRUITING Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
Dana-Farber Cancer Institute
NCT07054190 RECRUITING A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
Hoffmann-La Roche
NCT07109817 NOT YET RECRUITING Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer
Montefiore Medical Center
NCT06179303 RECRUITING Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer
University of Washington
NCT06875128 RECRUITING Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
Delcath Systems Inc.
NCT03808337 RECRUITING Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease
Memorial Sloan Kettering Cancer Center
NCT05467891 RECRUITING Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
Oana Danciu
NCT06206837 ACTIVE NOT RECRUITING A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.
Pfizer
NCT07162051 RECRUITING A Study on the Use of Fluzoparib Combined With Chemotherapy for Neoadjuvant Treatment of HRD-positive, HR+/HER2- Breast Cancer
Xijing Hospital
NCT06802757 RECRUITING Posaconazole Plus PD-1 Inhibitors and Chemotherapy vs PD-1 Inhibitors and Chemotherapy in Neoadjuvant Therapy for Triple Negative Breast Cancer
Shandong Cancer Hospital and Institute
NCT07371585 RECRUITING Trastuzumab Deruxtecan in First-Line HER2-Positive Metastatic Breast Cancer With Proactive Toxicity Management
SOLTI Breast Cancer Research Group
NCT06099769 RECRUITING A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT06449222 ACTIVE NOT RECRUITING Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy
BioNTech SE
NCT06695845 RECRUITING A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Jazz Pharmaceuticals
NCT07432633 RECRUITING [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
Blue Earth Diagnostics
NCT06100874 ACTIVE NOT RECRUITING A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)
Adrienne G. Waks
NCT06618287 RECRUITING A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT03179904 ACTIVE NOT RECRUITING TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer
Mayo Clinic
NCT04893109 RECRUITING ATEMPT 2.0: Adjuvant T-DM1 vs TH
Dana-Farber Cancer Institute
NCT06188520 RECRUITING A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
AstraZeneca
NCT02778685 ACTIVE NOT RECRUITING Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients With Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer
City of Hope Medical Center
NCT07368998 RECRUITING To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
Hoffmann-La Roche
NCT05969860 RECRUITING At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Mayo Clinic
NCT07427394 NOT YET RECRUITING Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer
AstraZeneca
NCT07428018 NOT YET RECRUITING Pragmatic Phase II Study to Optimize Neoadjuvant Treatment and Surgical De-escalation in HR+/HER2- Early Breast Cancer Using Oncotype DX and Abemaciclib
Mario Negri Institute for Pharmacological Research
NCT07193394 RECRUITING Tucatinib and Trastuzumab in HER3-mutant and HER2-not Amplified Metastatic Breast Cancer
Institut Curie
NCT05464082 RECRUITING Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC
University of Utah
NCT07102940 NOT YET RECRUITING Efti in Patients With Hormone Receptor Positive/HER2-neg Breast Cancer
George Washington University
NCT06998407 RECRUITING ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors
Avenzo Therapeutics, Inc.
NCT06827236 RECRUITING A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
BioNTech SE
NCT05721248 ACTIVE NOT RECRUITING STOP-HER2: Stopping Trastuzumab in HER2+ MBC
Dana-Farber Cancer Institute
NCT07423611 NOT YET RECRUITING ctDNA-Guided Chemotherapy Omission With Ribociclib Plus Endocrine Therapy in HR-Positive/HER2-Negative Breast Cancer
Fudan University
NCT07394946 NOT YET RECRUITING Neoadjuvant Letrozole in Postmenopausal Women With Hormone Receptor-Positive, HER2-Negative, Node Positive, Early-Stage Breast Cancer.
Cancer Care Hospital & Research Centre Foundation, Lahore
NCT07419867 NOT YET RECRUITING A Platform Study Based on Specific Tracer for Evaluating the Therapeutic Efficacy of Systemic Treatment for Breast Cancer Using PET/MRI
Fudan University
NCT04644068 ACTIVE NOT RECRUITING Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
AstraZeneca
NCT06595563 RECRUITING HER2 Molecular Imaging With 89Zr-trastuzumab PET/CT as a Predictive Biomarker for Antibody-drug Conjugate Sequencing in Patients With Advanced HER2-positive Breast Cancer
Jules Bordet Institute
NCT07419880 NOT YET RECRUITING Re-challenge Immunotherapy With Cromolyn, TQB2102, and Panpulimab in Immune-Refractory Triple Negative Breast Cancer
Fudan University
NCT06797635 RECRUITING Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
Merck Sharp & Dohme LLC
NCT07416253 NOT YET RECRUITING Trastuzumab Rezetecan vs Trastuzumab Deruxtecan in the Neoadjuvant Treatment of HER2 Positive Breast Cancer
Henan Cancer Hospital
NCT07410559 NOT YET RECRUITING Neoadjuvant Imlunestrant Plus Abemaciclib Treatment Guided by Ki67 Index After 2 Weeks for ER-Positive HER2-Negative Breast Cancer
Fudan University
NCT04176848 ACTIVE NOT RECRUITING CFI-400945 and Durvalumab in Patients With Advanced Triple Negative Breast Cancer
Canadian Cancer Trials Group
NCT07410676 RECRUITING EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Essen Biotech
NCT05660083 RECRUITING Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)
The Methodist Hospital Research Institute
NCT07227233 RECRUITING Artificial Intelligence and Machine Learning to Guide CDK4/6 Inhibitor Rechallenge in Breast Cancer.
University of California, San Diego
NCT07417241 NOT YET RECRUITING SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study
Peking University Cancer Hospital & Institute
NCT07410494 RECRUITING Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Essen Biotech
NCT06327490 RECRUITING A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
University of Florida
NCT05716893 RECRUITING Study of Aerobic Training for People Receiving Chemotherapy for Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT03587740 ACTIVE NOT RECRUITING ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer
Dana-Farber Cancer Institute
NCT07217990 NOT YET RECRUITING Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer
Ohio State University Comprehensive Cancer Center
NCT02927912 ACTIVE NOT RECRUITING Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction
Ohio State University Comprehensive Cancer Center
NCT07102381 RECRUITING A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
Jazz Pharmaceuticals
NCT05074290 RECRUITING Pharmacokinetics and Safety of Epidiferphane and Taxanes in Breast Cancer Patients
University of Florida
NCT05741164 NOT YET RECRUITING Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer
Emory University
NCT06348134 RECRUITING Assessing the Efficacy and Safety of Anti-HER2 Therapy in Nigerian Women With HER2+ Breast Cancer Before and After Surgery
University of Chicago
NCT04683679 RECRUITING A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT07123649 RECRUITING Individualizing Approaches to Surveillance Mammography in Older Breast Cancer Survivors - The I-MAMMO Study
Dana-Farber Cancer Institute
NCT03412877 RECRUITING Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
National Cancer Institute (NCI)
NCT07145255 RECRUITING Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
MBrace Therapeutics
NCT06224673 NOT YET RECRUITING ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer
Laura Huppert, MD, BA
NCT07285993 NOT YET RECRUITING Detection and Outcomes in Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAP PET
Randy Yeh
NCT06686394 RECRUITING Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
Merck Sharp & Dohme LLC
NCT03424005 RECRUITING A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Hoffmann-La Roche
NCT05123482 RECRUITING A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
AstraZeneca
NCT07410234 NOT YET RECRUITING Phase II Exploratory Study of Toripalimab Combined With SBRT in HER2-Negative Breast Cancer Patients With Insensitivity to Neoadjuvant Chemotherapy
Tianjin Medical University Cancer Institute and Hospital
NCT04802759 RECRUITING A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
Hoffmann-La Roche
NCT05892068 ACTIVE NOT RECRUITING A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain
Memorial Sloan Kettering Cancer Center
NCT06105632 ACTIVE NOT RECRUITING A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
Pfizer
NCT07158021 RECRUITING Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial
University of Michigan Rogel Cancer Center
NCT07100106 RECRUITING A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
Genentech, Inc.
NCT06068985 ACTIVE NOT RECRUITING Classifying for HER2 Dependence to De-Escalate Neoadjuvant Chemotherapy in Patients With HER2+ Early Breast Cancer Undergoing HER2 Double-Blockade
Latin American Cooperative Oncology Group
NCT07405801 NOT YET RECRUITING A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
Hoffmann-La Roche
NCT05985655 RECRUITING Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.
NCT07406789 NOT YET RECRUITING Phase II, Prospective, Randomized, Proof-of-concept Study to Evaluate the Effects of a Personalized Dietary Intervention in Women With Advanced Gynecologic or Breast Tumors Treated With Antibody-Drug Conjugates (ADCs).
TNC Nutrición Terapéutica S.L.
NCT06517212 RECRUITING Tirzepatide Weight Loss for MRD+ Early Breast Cancer
Baylor Research Institute
NCT02624973 ACTIVE NOT RECRUITING PErsonalized TREatment of High-risk MAmmary Cancer - the PETREMAC Trial
Haukeland University Hospital
NCT07071038 RECRUITING Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer Patients
Dartmouth-Hitchcock Medical Center
NCT04348747 RECRUITING Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
Roswell Park Cancer Institute
NCT07407920 ACTIVE NOT RECRUITING Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial
M.D. Anderson Cancer Center
NCT05601440 RECRUITING Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer
Canadian Cancer Trials Group
NCT07188246 RECRUITING Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy in Breast Cancer
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
NCT04001829 ACTIVE NOT RECRUITING Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer
ECOG-ACRIN Cancer Research Group
NCT07402473 NOT YET RECRUITING EUREKA Study:Phase 2 Study to Optimize Neoadjuvant Therapy in HER2-positive Early-stage Breast Cancer
Rutgers, The State University of New Jersey
NCT07376538 RECRUITING Response-Based Local Therapy for Regionally Advanced Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05383196 ACTIVE NOT RECRUITING Onvansertib + Paclitaxel In TNBC
Antonio Giordano, MD
NCT04585750 RECRUITING The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
PMV Pharmaceuticals, Inc
NCT04072952 ACTIVE NOT RECRUITING A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer
Arvinas Estrogen Receptor, Inc.
NCT07401537 RECRUITING Efficacy and Safety of Extended-Dose Interval Immunotherapy Versus Standard-Dose Interval Immunotherapy for Advanced Triple-Negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06064812 RECRUITING A Phase I/II Study of FWD1802 in Patients With ER+/HER2- Advanced BC.
Forward Pharmaceuticals Co., Ltd.
NCT05548127 ACTIVE NOT RECRUITING TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)
Pfizer
NCT06917313 RECRUITING FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
Yale University
NCT07340541 NOT YET RECRUITING Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
UNC Lineberger Comprehensive Cancer Center
NCT04478279 ACTIVE NOT RECRUITING A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
Sapience Therapeutics
NCT07395336 NOT YET RECRUITING Elacestrant and Exemestane for Patients With Pretreated HR+/HER2- Metastatic Breast Cancer and [18F] FES-avid Lesions (COMBINE)
European Institute of Oncology
NCT06129747 RECRUITING Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
Case Comprehensive Cancer Center
NCT06374459 RECRUITING Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
Washington University School of Medicine
NCT07396324 NOT YET RECRUITING Neoadjuvant Iparomlimab and Tuvonralimab (QL1706) in Patients With Hormone Receptor Positive, HER2-negative Breast Cancer
RenJi Hospital
NCT07394218 RECRUITING ctDNA-guided Treatment Decision-making
Fudan University
NCT07393425 RECRUITING Neoadjuvant Trastuzumab Deruxtecan (SHR-A1811) + Pertuzumab in HER2+ Breast Cancer
Shanghai Jiao Tong University School of Medicine
NCT02747004 ACTIVE NOT RECRUITING A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer
Eli Lilly and Company
NCT04923542 RECRUITING Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute
NCT03789110 ACTIVE NOT RECRUITING NIMBUS: Nivolumab Plus Ipilimumab in Metastatic Hypermutated HER2-negative Breast Cancer
Dana-Farber Cancer Institute
NCT04573231 RECRUITING Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer
University of Wisconsin, Madison
NCT07001241 RECRUITING Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
University of Colorado, Denver
NCT02876302 ACTIVE NOT RECRUITING Study Of Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer
Dana-Farber Cancer Institute
NCT07383818 RECRUITING Neoadjuvant Therapy Combined With Trastuzumab Rezetecan and Toripalimab for HR+/HER2-low Breast Cancer (NEOTORCH-BREAST 08)
First Affiliated Hospital of Zhejiang University
NCT07007559 RECRUITING ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies
ALX Oncology Inc.
NCT07380646 NOT YET RECRUITING the Efficacy of Leucogen in Preventing the Risk of Ribociclib-Associated Neutropenia in Early Breast Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT06833502 RECRUITING Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT07287917 RECRUITING Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
Aminex Therapeutics, Inc.
NCT07378306 NOT YET RECRUITING FMD and Neoadjuvant Chemo-immunotherapy in TNBC
Sun Yat-sen University
NCT03624543 ACTIVE NOT RECRUITING CFI-400945 in Patients With Advanced/Metastatic Breast Cancer
Canadian Cancer Trials Group
NCT04680715 RECRUITING Per-Operative Radiotherapy by Papillon +TM in Localized Breast Cancer
Centre Antoine Lacassagne
NCT07370506 NOT YET RECRUITING Telmisartan for Prevention of Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients
Tanta University
NCT05305924 RECRUITING Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer
The Methodist Hospital Research Institute
NCT06172478 RECRUITING A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Daiichi Sankyo
NCT07367178 NOT YET RECRUITING Study of Sacituzumab Govitecan With Atropine to Improve Tolerability in Advanced TNBC and HR+/HER2- Breast Cancer
MedSIR
NCT07368543 NOT YET RECRUITING Sequencing SG vs. T-DXd in HER2-Low/TROP2-High Metastatic Breast Cancer
Fudan University
NCT06860815 RECRUITING Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer
City of Hope Medical Center
NCT06926075 RECRUITING Early Phase Study of Kesonotide in Participants With Solid Tumours
Filamon LTD
NCT03804944 RECRUITING Converting HR+ Breast Cancer Into an Individualized Vaccine
Weill Medical College of Cornell University
NCT07372079 NOT YET RECRUITING Neoadjuvant Therapy for Early Triple-Negative Breast Cancer: A Response-Guided Approach Using Iparomlimab and Tuvonralimab Injection in Combination With Chemotherapy
Tianjin Medical University Cancer Institute and Hospital
NCT05968144 ACTIVE NOT RECRUITING Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness
University of Maryland, Baltimore
NCT06715826 RECRUITING Target-specific immunoPET Imaging of Breast Cancer
RenJi Hospital
NCT07371208 RECRUITING Multicenter, Phase II Clinical Study of Sacituzumab Tirumotecan (Sac-TMT) in Combination With KL-A167 for Neoadjuvant Treatment of Triple-Negative Breast Cancer
Shanghai Jiao Tong University School of Medicine
NCT04316117 ACTIVE NOT RECRUITING Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study
ECOG-ACRIN Cancer Research Group
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Peking University People's Hospital
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University of Alabama at Birmingham
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M.D. Anderson Cancer Center
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M.D. Anderson Cancer Center
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MedSIR
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YING FAN
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Kristina A. Fanucci
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University of Washington
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Second Affiliated Hospital, School of Medicine, Zhejiang University
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HealthPartners Institute
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Phoenix Molecular Designs
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Peking University People's Hospital
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Rutgers, The State University of New Jersey
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Fudan University
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Kathy Miller
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Kidney Cancer Research Bureau
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University of Chicago
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Fudan University
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Dartmouth-Hitchcock Medical Center
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Dartmouth-Hitchcock Medical Center
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Sonya Reid
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National Cancer Institute (NCI)
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Hoffmann-La Roche
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Carrick Therapeutics Limited
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Dana-Farber Cancer Institute
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Second Life Therapeutics
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Ana C Garrido-Castro, MD
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University of Illinois at Chicago
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Dartmouth-Hitchcock Medical Center
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Dana-Farber Cancer Institute
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University of Miami
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BicycleTx Limited
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Jiangsu Alphamab Biopharmaceuticals Co., Ltd
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Memorial Sloan Kettering Cancer Center
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Novartis Pharmaceuticals
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Shanghai Jiao Tong University School of Medicine
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Filipa Lynce, MD
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Criterium, Inc.
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Shandong Suncadia Medicine Co., Ltd.
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Zhejiang Cancer Hospital
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Washington University School of Medicine
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Pfizer
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Jacobio Pharmaceuticals Co., Ltd.
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Henan Cancer Hospital
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Hoffmann-La Roche
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Tel-Aviv Sourasky Medical Center
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Irada Ibrahim-zada
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OHSU Knight Cancer Institute
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Forward Pharmaceuticals Co., Ltd.
NCT05501704 RECRUITING ETHAN - ET for Male BC
Jose Pablo Leone
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Wake Forest University Health Sciences
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M.D. Anderson Cancer Center
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University of Alabama at Birmingham
NCT04872985 ACTIVE NOT RECRUITING Pyrotinib Plus Neoadjuvant Chemotherapy in HR+/HER2-, HER4-High Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
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Stemline Therapeutics, Inc.
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Mayo Clinic
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UNC Lineberger Comprehensive Cancer Center
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Ensem Therapeutics
NCT03344965 ACTIVE NOT RECRUITING Olaparib In Metastatic Breast Cancer
Beth Israel Deaconess Medical Center
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Cancer Institute and Hospital, Chinese Academy of Medical Sciences
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M.D. Anderson Cancer Center
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Memorial Sloan Kettering Cancer Center
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Asan Medical Center
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Shantou Central Hospital
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Marina N Sharifi
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Nancy Chan, MD
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Esbjerg Hospital - University Hospital of Southern Denmark
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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT04141449 ACTIVE NOT RECRUITING A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation
Brigham and Women's Hospital
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Jiangsu HengRui Medicine Co., Ltd.
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National Cancer Centre, Singapore
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Swiss Cancer Institute
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Tianjin Medical University Cancer Institute and Hospital
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Acerand Therapeutics (Shanghai) Limited
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Mayo Clinic
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Reshma L. Mahtani, D.O.
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Merck Sharp & Dohme LLC
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First Hospital of China Medical University
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Yeon Hee Park
NCT05256745 RECRUITING RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer
Georgetown University
NCT05305365 ACTIVE NOT RECRUITING Study Assessing QBS72S For Treating Brain Metastases
Stanford University
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Gustave Roussy, Cancer Campus, Grand Paris
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Anhui Provincial Cancer Hospital
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Colette Shen
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Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
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The First Affiliated Hospital of Bengbu Medical University
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Nathalie Levasseur
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Memorial Sloan Kettering Cancer Center
NCT07285044 RECRUITING The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Mayo Clinic
NCT05069038 ACTIVE NOT RECRUITING Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy
University of Nebraska
NCT06923527 RECRUITING Circulating Tumor DNA
Yale University
NCT05035836 RECRUITING A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)
M.D. Anderson Cancer Center
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H. Lee Moffitt Cancer Center and Research Institute
NCT03285412 ACTIVE NOT RECRUITING CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer
Massachusetts General Hospital
NCT07275463 ENROLLING BY INVITATION [99mTc]Tc-DB8 Accumulation in Primary Tumor in Breast Cancer With Positive and Negative Estrogen Receptor Expression
Tomsk National Research Medical Center of the Russian Academy of Sciences
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UNICANCER
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Tianjin Medical University Cancer Institute and Hospital
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University of Illinois at Chicago
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Duke University
NCT07290166 NOT YET RECRUITING A Phase II Study to Evaluate the Efficacy and Safety of Anti-HER2 Triple-targeted Drugs Combined With CDK4/6 Inhibitors in Neoadjuvant Therapy for ER-positive HER2-positive Breast Cancer Patients.
Fudan University
NCT07292207 NOT YET RECRUITING Abemaciclib for Molecular Residual Disease Detected by Circulating Tumor DNA in HR+/HER2- Early Breast Cancer
Nagoya City University
NCT07292142 NOT YET RECRUITING FMT in Triple Negative Breast Cancer Guided by ctDNA
Jewish General Hospital
NCT07292571 ENROLLING BY INVITATION Evaluation of Different Types of HER2 Expression in Breast Cancer Using [99mTc]Tc -ZHER2:4107
Tomsk National Research Medical Center of the Russian Academy of Sciences
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Incyte Corporation
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Hoffmann-La Roche
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Wake Forest University Health Sciences
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Memorial Sloan Kettering Cancer Center
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Emory University
NCT07285382 RECRUITING Different Doses of Dalpicicl Combined With Letrozole in the First-line Treatment of HR-positive, HER2-negative Advanced Breast Cancer
wanghaibo
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Zhejiang Cancer Hospital
NCT05226663 ACTIVE NOT RECRUITING A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer
M.D. Anderson Cancer Center
NCT07078604 NOT YET RECRUITING A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer
University of Washington
NCT07112053 RECRUITING A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer
University of Washington
NCT04563507 RECRUITING Combined Immunotherapies in Metastatic ER+ Breast Cancer
Weill Medical College of Cornell University
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AHS Cancer Control Alberta
NCT04965064 RECRUITING Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling
University of Rochester
NCT06635980 RECRUITING Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer
Mayo Clinic
NCT06157892 RECRUITING A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
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MedSIR
NCT05812924 ACTIVE NOT RECRUITING A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause
University of Miami
NCT06518057 RECRUITING Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
University of Washington
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Tanabe Pharma America, Inc.
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Hebei Medical University Fourth Hospital
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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Puma Biotechnology, Inc.
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Alice Chung
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Dana-Farber Cancer Institute
NCT06961955 RECRUITING 5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer
University of Utah
NCT04538742 ACTIVE NOT RECRUITING A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
AstraZeneca
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City of Hope Medical Center
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MedSIR
NCT07117630 RECRUITING An Open-Label, Bayesian Adaptive Phase II Clinical Study in HR+/HER2- Advanced Breast Cancer After Progression on Standard Therapy
Fudan University
NCT06238921 RECRUITING Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute
NCT05318469 RECRUITING Ivermectin in Combination With Balstilimab or Pembrolizumab in Patients With Metastatic Triple Negative Breast Cancer
Yuan Yuan
NCT06731894 RECRUITING Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors
City of Hope Medical Center
NCT03384914 ACTIVE NOT RECRUITING Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
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Mayo Clinic
NCT06409390 RECRUITING Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
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Mayo Clinic
NCT04373031 ACTIVE NOT RECRUITING Pembrolizumab, IRX-2, and Chemotherapy in Triple Negative Breast Cancer
Providence Health & Services
NCT07258108 NOT YET RECRUITING Lucentis Plus Tagolimumab in PD-L1+, HR+/HER2- Advanced Breast Cancer After CDK4/6 Inhibitors
Sun Yat-sen University
NCT07259226 RECRUITING Optimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Biomarkers
UNICANCER
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Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd.
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GBG Forschungs GmbH
NCT07159451 RECRUITING A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer
Gustave Roussy, Cancer Campus, Grand Paris
NCT07255612 NOT YET RECRUITING Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer)
Sun Yat-sen University
NCT06843681 ENROLLING BY INVITATION Trastuzumab Plus Taxane Neoadjuvant Therapy for HER2-Positive Breast Ductal Carcinoma In Situ (DCIS) : A Phase II Study
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
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Tianjin Medical University Cancer Institute and Hospital
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Centre Leon Berard
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MediLink Therapeutics (Suzhou) Co., Ltd.
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Pfizer
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Dana-Farber Cancer Institute
NCT07245069 RECRUITING Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients
University Medical Centre Ljubljana
NCT02849496 ACTIVE NOT RECRUITING Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer
National Cancer Institute (NCI)
NCT07245797 NOT YET RECRUITING A Phase II, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Neoadjuvant Therapy With Inavolisib Plus Pertuzumab and Trastuzumab as Subcutaneous (PH-FDC SC) and 3-week Cycle Nab-paclitaxel for PIK3CA-mutated, HER2+, eBC
Zhimin Shao
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Fujian Cancer Hospital
NCT06185205 RECRUITING ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy
Virginia Commonwealth University
NCT04733118 ACTIVE NOT RECRUITING Chemotherapy-Free pCR-Guided Strategy With Trastuzumab-pertuzumab and T-DM1 in HER2-positive Early Breast Cancer
MedSIR
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Seoul National University Hospital
NCT06535893 RECRUITING Sustainable and Efficient Platform Trial of New Therapeutic Development for Early Breast Cancer
Nagoya City University
NCT03879629 ACTIVE NOT RECRUITING Treating Breast Cancer Patients Undergoing Trastuzumab Treatment With Carvedilol to Reduce Incidence of Heart Failure
Mayo Clinic
NCT07235618 NOT YET RECRUITING A Study of Entinostat in Combination With Fulvestrant for the Treatment of Locally Advanced or Metastatic Breast Cancer
Sun Yat-sen University
NCT05704829 ACTIVE NOT RECRUITING NeoAdjuvant Therapy With Trastuzumab-deruxtecan Versus Chemotherapy+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer
West German Study Group
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Avenzo Therapeutics, Inc.
NCT04986579 RECRUITING Scalp Cooling in MBC
Dana-Farber Cancer Institute
NCT06649331 RECRUITING Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer
Fudan University
NCT05800275 RECRUITING Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease
UNICANCER
NCT07180160 RECRUITING Iparomlimab and Tuvonralimab (QL1706) in Patients With HR-positive, HER2-negative Advanced Breast Cancer
Wenjin Yin
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Minghui Pharmaceutical (Hangzhou) Ltd
NCT07076485 RECRUITING Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer
M.D. Anderson Cancer Center
NCT04425018 ACTIVE NOT RECRUITING MARGetuximab Or Trastuzumab (MARGOT)
Dana-Farber Cancer Institute
NCT06364267 RECRUITING Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer.
Andrea DeCensi
NCT07180082 RECRUITING Continuous or Intermittent Pyrotinib for HER2-positive Advanced Breast Cancer
Wenjin Yin
NCT05041842 ACTIVE NOT RECRUITING Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer
UNICANCER
NCT06731140 RECRUITING Reverse HER2-negative Immune Resistant Breast Cancer
Fudan University
NCT05559164 RECRUITING Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
Rutgers, The State University of New Jersey
NCT02827877 ACTIVE NOT RECRUITING Cu64-DOTA-trastuzumab PET and Markers Predicting Response to Neoadjuvant Trastuzumab + Pertuzum in HER2+ Breast Cancer
City of Hope Medical Center
NCT04829604 ACTIVE NOT RECRUITING ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
Ambrx, Inc.
NCT04569747 RECRUITING A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer
Dana-Farber Cancer Institute
NCT04553770 RECRUITING Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
Jonsson Comprehensive Cancer Center
NCT02311933 ACTIVE NOT RECRUITING Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer
National Cancer Institute (NCI)
NCT07191717 NOT YET RECRUITING Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI Trial
Jonsson Comprehensive Cancer Center
NCT07203378 RECRUITING Nurturing Exercise Routine for Greater Improvement in Zest and Energy on Enhertu
University of Utah
NCT06247995 RECRUITING A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
Novartis Pharmaceuticals
NCT04329065 RECRUITING Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer
University of Washington
NCT06444269 RECRUITING Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
University of Texas Southwestern Medical Center
NCT07198724 NOT YET RECRUITING ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer
Sarah Sammons, MD
NCT05675579 ACTIVE NOT RECRUITING A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)
M.D. Anderson Cancer Center
NCT03707340 ACTIVE NOT RECRUITING A Study of Flibanserin in Breast Cancer Survivors on Tamoxifen or Aromatase Inhibitors
Memorial Sloan Kettering Cancer Center
NCT06125522 ACTIVE NOT RECRUITING TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)
Pfizer
NCT05607004 RECRUITING (Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
Atossa Therapeutics, Inc.
NCT07016399 RECRUITING Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC
Vandana Abramson
NCT04529044 NOT YET RECRUITING 177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer
OHSU Knight Cancer Institute
NCT02713269 ACTIVE NOT RECRUITING Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord
M.D. Anderson Cancer Center
NCT06897488 RECRUITING EMERALD: Endocrine Therapy oMission With Radiation in ER+ Breast Cancer: Assessing Quality of Life and Disease Control: a Prospective Phase II Trial
M.D. Anderson Cancer Center
NCT04821141 ACTIVE NOT RECRUITING Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens
University of Kansas Medical Center
NCT06954831 RECRUITING Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer
City of Hope Medical Center
NCT05608252 RECRUITING VS-6766+Abema+Fulv in Met HR+/HER- BC
Adrienne G. Waks
NCT02700386 ACTIVE NOT RECRUITING Shorter Course Radiation for the Treatment of Breast Cancer That Has Spread to Lymph Nodes
University of Colorado, Denver
NCT03546686 RECRUITING Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer
University of Texas Southwestern Medical Center
NCT05090358 ACTIVE NOT RECRUITING Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT05570253 RECRUITING A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT05455658 ACTIVE NOT RECRUITING STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
University of Washington
NCT06533826 RECRUITING TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd
Ana C Garrido-Castro, MD
NCT07220135 NOT YET RECRUITING Trial of Neoadjuvant THP vs TCHP for HER2-Amplified/Positive Breast Cancer
University of Kansas Medical Center
NCT04272801 ACTIVE NOT RECRUITING Pre-Operative Window of Adjuvant Endocrine Therapy to Inform RT Decisions in Older Women With Early-Stage Breast Cancer
Shayna Showalter, MD
NCT04886531 RECRUITING Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
Ruth O'Regan
NCT02754752 ACTIVE NOT RECRUITING Electroacupuncture Therapy in Reducing Chronic Pain in Patients After Breast Cancer Treatment
M.D. Anderson Cancer Center
NCT06062498 RECRUITING Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer
Northwestern University
NCT04567420 RECRUITING DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
Criterium, Inc.
NCT02883062 ACTIVE NOT RECRUITING Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer
National Cancer Institute (NCI)
NCT05565417 ACTIVE NOT RECRUITING Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas
Immunitas Therapeutics
NCT05900986 ACTIVE NOT RECRUITING LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer
Integro Theranostics
NCT05573126 RECRUITING Phase 1/2 Study to Evaluate Vosilasarm (EP0062) as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
Ellipses Pharma
NCT06361940 RECRUITING Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer
Medical College of Wisconsin
NCT07173101 RECRUITING Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients
University of Utah
NCT04230109 RECRUITING Sacituzumab Govitecan In TNBC
Massachusetts General Hospital
NCT06810804 RECRUITING A Phase IIa Study to Evaluate NBQ72S
Nantong Bencao Quadriga Medical Technology Co. Ltd.
NCT02876107 ACTIVE NOT RECRUITING Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer
M.D. Anderson Cancer Center
NCT06450873 RECRUITING Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery
Mayo Clinic
NCT06042569 RECRUITING Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial
City of Hope Medical Center
NCT04009044 ACTIVE NOT RECRUITING Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast
Northwestern University
NCT02414269 ACTIVE NOT RECRUITING Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Memorial Sloan Kettering Cancer Center
NCT05645380 RECRUITING Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC
University of Kansas Medical Center
NCT07017673 RECRUITING Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer
Cedars-Sinai Medical Center
NCT05534438 RECRUITING A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT06260033 RECRUITING Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer
City of Hope Medical Center
NCT02393794 ACTIVE NOT RECRUITING Cisplatin Plus Romidepsin & Nivolumab in Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC)
Priyanka Sharma
NCT06525766 RECRUITING Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer
Mayo Clinic
NCT07195227 NOT YET RECRUITING Efficacy and Safety of Camizestrant Plus Ribociclib in Patients With Breast Cancer
MedSIR
NCT07203729 NOT YET RECRUITING The Efficacy and Safety of Trastuzumab Rezetecan (SHR-A1811) in HER2-Low Unresectable/Metastatic Breast Cancer Patients With Visceral Crisis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04837209 ACTIVE NOT RECRUITING Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer
Massachusetts General Hospital
NCT07054242 NOT YET RECRUITING A Prospective, Single-center, Phase II Study of Sacituzumab Tirumotecan in Combination With Pembrolizumab for Neoadjuvant Treatment of Triple-Negative Breast Cancer (TNBC)
Yantai Yuhuangding Hospital
NCT06086704 RECRUITING Study of 18F-FFNP Breast PET/MRI
University of Wisconsin, Madison
NCT06640881 RECRUITING Preoperative Partial Breast Reirradiation and Repeat Breast-conserving Surgery in Patients With Recurrent Breast Cancer: the REPEAT Trial
Amsterdam UMC, location VUmc
NCT06178159 RECRUITING DV in Combination With Pertuzumab With or Without Toripalimab Neoadjuvant Therapy With HER2-positive Breast Cancer
RemeGen Co., Ltd.
NCT04454528 RECRUITING BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy
Abramson Cancer Center at Penn Medicine
NCT03147287 ACTIVE NOT RECRUITING Palbociclib After CDK and Endocrine Therapy (PACE)
Dana-Farber Cancer Institute
NCT07197697 NOT YET RECRUITING A Phase II Exploratory Study of Iparomlimab and Tuvonralimab Combined With Chemotherapy in Neoadjuvant Treatment of HR+/HER2- Breast Cancer Patients
Anhui Provincial Cancer Hospital
NCT03414684 ACTIVE NOT RECRUITING Carboplatin +/- Nivolumab in Metastatic Triple Negative Breast Cancer
Dana-Farber Cancer Institute
NCT03359954 ACTIVE NOT RECRUITING Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer
M.D. Anderson Cancer Center
NCT06042894 RECRUITING A Study of SI-B003 or BL-B01D1+SI-B003 in Patients With Unresectable Locally Advanced or Recurrent Metastatic HER2 Negative Breast Cancer
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06710197 RECRUITING IL-1 Inhibition in Early TNBC
University Health Network, Toronto
NCT02562118 ACTIVE NOT RECRUITING Neoadjuvant Lenvatinib Combined With Letrozole in Hormone Receptor Positive Breast Cancer
National University Hospital, Singapore
NCT04520269 ACTIVE NOT RECRUITING A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)
National University Hospital, Singapore
NCT02498613 ACTIVE NOT RECRUITING A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors
National Cancer Institute (NCI)
NCT05866432 RECRUITING Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases
Medical University of Vienna
NCT06335069 RECRUITING 18F-FDG Versus 68Ga-FAPI-46 as PET Tracer in ER-positive Breast Cancer.
Maastricht University Medical Center
NCT06827613 RECRUITING A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors
Marengo Therapeutics, Inc.
NCT04305834 RECRUITING Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.
City of Hope Medical Center
NCT07189884 NOT YET RECRUITING Pyrotinib Maleate Tablets in Combination With Dalpiciclib Isethionate Tablets and Standard Endocrine Therapy
The First Affiliated Hospital of Xiamen University
NCT05381038 RECRUITING Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI
National University Hospital, Singapore
NCT04280536 ACTIVE NOT RECRUITING Phase II Study of FTD/TPI (Lonsurf) in Metastatic Breast Cancers With or Without Prior Exposure to Fluoropyrimidines (LONBRECA)
National University Hospital, Singapore
NCT06027983 NOT YET RECRUITING Chimeric Receptor T Cells With Trastuzumab in HER2+ Advanced Breast Cancer and Other Solid Tumors
National University Hospital, Singapore
NCT06680596 ENROLLING BY INVITATION Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd Therapy
UNICANCER
NCT03573648 ACTIVE NOT RECRUITING Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04273061 RECRUITING Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
British Columbia Cancer Agency
NCT05810870 RECRUITING PIK3CA/PTEN-altered Advanced Breast Cancer Treated With MEN1611 Monotherapy or in Combination With Eribulin
MedSIR
NCT07182721 RECRUITING SKB264 Plus Inetetamab in HER2-Positive Metastatic Breast Cancer Patients Progressing After T-DXd Treatment
Fudan University
NCT05735080 RECRUITING Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
Incyclix Bio
NCT03820063 ACTIVE NOT RECRUITING Image-guided De-escalation of Neo-adjuvant Chemotherapy in HER2-positive Breast Cancer: the TRAIN-3 Study
Borstkanker Onderzoek Groep
NCT04293393 ACTIVE NOT RECRUITING Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients
Spanish Breast Cancer Research Group
NCT05795101 RECRUITING TRUDI: TDXD+Durva in HER2+/Low IBC
Filipa Lynce, MD
NCT04090567 RECRUITING Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer
M.D. Anderson Cancer Center
NCT07177950 NOT YET RECRUITING A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases
Peking University Cancer Hospital & Institute
NCT04084730 RECRUITING Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT07173556 NOT YET RECRUITING A Phase Ib/II Study of QLC1401 Combined With CDK4/6 or mTOR Inhibitors in ER+/HER2- Advanced Breast Cancer
Qilu Pharmaceutical Co., Ltd.
NCT03515798 ACTIVE NOT RECRUITING Study of Immunotherapy in Combination With Chemotherapy in HER2-negative Inflammatory Breast Cancer
Institut Paoli-Calmettes
NCT07169994 RECRUITING A Study of YL202 in Combination With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd.
NCT07080619 NOT YET RECRUITING SC-101 in Subjects With Advanced NECTIN4-Amplified Cancers
Tianjin ConjuStar Biologics Co., Ltd.
NCT04126525 ACTIVE NOT RECRUITING Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer
RenJi Hospital
NCT04138719 RECRUITING Nab-paclitaxel Plus Carboplatin Versus Nab-paclitaxel Plus Epirubicin in the Neoadjuvant Therapy for Breast Cancer
Hebei Medical University Fourth Hospital
NCT07164976 NOT YET RECRUITING Ribociclib for HR-positive HER2-negative Metastatic Breast Cancer
Nagoya City University
NCT05130801 RECRUITING A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery
Memorial Sloan Kettering Cancer Center
NCT05919108 RECRUITING Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
Vanderbilt-Ingram Cancer Center
NCT07161791 NOT YET RECRUITING Camrelizumab, Pirfenidone, and Chemotherapy in the Treatment of Advanced Triple-Negative Breast Cancer
Harbin Medical University
NCT07162298 RECRUITING Dragon Boat Race Versus Family Unsupervised Training to Improve the Physical Function and Quality of Life in Breast Cancer Patients
First Affiliated Hospital of Zhejiang University
NCT04759248 ACTIVE NOT RECRUITING Study With Atezolizumab in Combination With Trastuzumab and Vinorelbine in HER2-positive Advanced/Metastatic Breast Cancer
SOLTI Breast Cancer Research Group
NCT04243616 ACTIVE NOT RECRUITING Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer
Medical College of Wisconsin
NCT07151586 NOT YET RECRUITING Testing Two Different Drugs (Sacituzumab-govitecan and Trastuzumab-deruxtecan) Combinations Prescribed in an Alterning Pattern to Patients With Metastatic or Locally Advanced Triple-negative Breast Cancer
UNICANCER
NCT07152782 NOT YET RECRUITING T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis
Fudan University
NCT06727773 RECRUITING Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
UNC Lineberger Comprehensive Cancer Center
NCT07150208 NOT YET RECRUITING T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis
Fudan University
NCT05900206 RECRUITING Trastuzumab Deruxtecan Versus Standard Neoadjuvant Treatment for HER2-positive Breast Cancer
Karolinska University Hospital
NCT06954623 RECRUITING Partial Breast Re-irradiation for Breast Cancer
University Hospital Heidelberg
NCT06538389 RECRUITING High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
City of Hope Medical Center
NCT06616987 RECRUITING Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer
Yeon Hee Park
NCT05374915 ACTIVE NOT RECRUITING Efficacy and Safety Study of REM-001 Photodynamic Therapy for Treatment of Cutaneous Metastatic Breast Cancer (CMBC)
Kintara Therapeutics, Inc.
NCT04553133 ACTIVE NOT RECRUITING PF-07104091 as a Single Agent and in Combination Therapy
Pfizer
NCT02957968 ACTIVE NOT RECRUITING Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca
Virginia Commonwealth University
NCT05458284 ACTIVE NOT RECRUITING The Effect of Acupuncture on Nerve Pain Caused by Taxane (Chemotherapy) Treatment
Memorial Sloan Kettering Cancer Center
NCT05491226 ACTIVE NOT RECRUITING Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation
Stephen Shiao
NCT07015853 NOT YET RECRUITING ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation
Stephen Shiao
NCT07129187 NOT YET RECRUITING SHR-A1811 for HER2-positive Breast Cancer With Suboptimal Neoadjuvant Response
Chuan Wang
NCT05582499 RECRUITING Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
Fudan University
NCT07137793 RECRUITING Clinical Study to Evaluate The Cardioprotective Effect of Pentoxifylline Against Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients
Tanta University
NCT07136974 NOT YET RECRUITING Efficacy of TQB2102 Versus TCbHP in Neoadjuvant Therapy for HER2-positive Early Breast Cancer.
Henan Cancer Hospital
NCT06599216 ACTIVE NOT RECRUITING Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR + / HER2- Breast Cancer
Harbin Medical University
NCT07134153 RECRUITING Phase I/II Study of Intrathecal/Ommaya T-DXd in HER2-Expressing Breast Cancer With Leptomeningeal/Brain Metastases
Fudan University
NCT05625087 ACTIVE NOT RECRUITING Detection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or Ribociclib
UNICANCER
NCT07132242 NOT YET RECRUITING SHR-A1811 Combine With Pyrotinib for Locally Advanced/Metastatic HER2 Positive Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04434040 RECRUITING Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
Dana-Farber Cancer Institute
NCT06198751 ACTIVE NOT RECRUITING A Study of Neoadjuvant Treatment With TQB2102 for Injection for Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT07107217 NOT YET RECRUITING Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer
Blokhin's Russian Cancer Research Center
NCT05872347 RECRUITING Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.
Shanghai Pharmaceuticals Holding Co., Ltd
NCT07125950 NOT YET RECRUITING SHR2554 Combined With Endocrine Therapy in Advanced Breast Cancer
Henan Cancer Hospital
NCT05864144 ACTIVE NOT RECRUITING A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Sensei Biotherapeutics, Inc.
NCT06556862 NOT YET RECRUITING Exploration of Dalpiciclib Plus HDACi in HR+/HER2- Advanced Breast Cancer After Failure of CDK4/6 Inhibitor
Beijing 302 Hospital
NCT03439735 ACTIVE NOT RECRUITING Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for HR+ MBC
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06590857 RECRUITING Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
RayzeBio, Inc.
NCT06478589 RECRUITING Patient Priorities for Survivorship Care in Older Breast Cancer Survivors
The University of Texas Health Science Center, Houston
NCT07100600 RECRUITING Trastuzumab Rezetecan Combined With Radiotherapy Versus Trastuzumab Rezetecan in the Treatment of HER2-positive Advanced Breast Cancer With Brain Metastases
Henan Cancer Hospital
NCT07113613 RECRUITING Prospective Study on Exemption of Tumor Bed Boost Radiotherapy for pCR Patients After Breast Conserving Surgery With Neoadjuvant Therapy
The First Affiliated Hospital with Nanjing Medical University
NCT03990896 RECRUITING Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
Massachusetts General Hospital
NCT05573555 ACTIVE NOT RECRUITING TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)
Pfizer
NCT04039230 RECRUITING Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.
Massachusetts General Hospital
NCT06395519 RECRUITING A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
858 Therapeutics, Inc.
NCT07103447 NOT YET RECRUITING Prospective Multicenter Single-arm Trial: AK112 + Nab-paclitaxel/Carboplatin Neoadjuvant for TNBC
Shuangyue Liu
NCT05524584 ACTIVE NOT RECRUITING Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
University of California, Irvine
NCT07101159 NOT YET RECRUITING Dalpiciclib as Adjuvant Therapy for HR-positive/HER2-negative Early-stage Patients
Fujian Cancer Hospital
NCT03936478 RECRUITING Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer
University of Wisconsin, Madison
NCT03627988 ACTIVE NOT RECRUITING Prospective, Multicentric Study Evaluating the Surgical Treatment by Mastectomy With Immediate Prosthetic Breast Reconstruction in Patients With Breast Cancer and Receiving Adjuvant Therapy by TomoTherapy +/-Chemotherapy.
Institut Claudius Regaud
NCT05806138 ACTIVE NOT RECRUITING A Study of Vericiguat in People With Breast Cancer and Cancer Therapy-Related Cardiac Dysfunction
Memorial Sloan Kettering Cancer Center
NCT06176261 RECRUITING DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
Sarah Sammons, MD
NCT05676255 RECRUITING The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
University of Arizona
NCT07007780 NOT YET RECRUITING Sacituzumab Tirumotecan in Neoadjuvant Treatment of Early-Stage TNBC
Xijing Hospital
NCT07044310 RECRUITING 5-strain Probiotic Formulation in HR-positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone Loss
Mayo Clinic
NCT04482244 ACTIVE NOT RECRUITING RCT of CBD for Anxiety in Advanced Breast Cancer
Dana-Farber Cancer Institute
NCT02476786 RECRUITING Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
Washington University School of Medicine
NCT04584255 ACTIVE NOT RECRUITING Niraparib + Dostarlimab In BRCA Mutated Breast Cancer
Dana-Farber Cancer Institute
NCT06224244 ACTIVE NOT RECRUITING External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients
Regina Elena Cancer Institute
NCT05181033 RECRUITING Lenvatinib+Letrozole Versus Fulvestrant in Metastatic ER+/HER2- Breast Cancer, Post Progression on Al + CDK4/6 Inhibitor
National University Hospital, Singapore
NCT07083505 NOT YET RECRUITING A Study Comparing the Efficacy and Safety of HB1801 With Taxotere® in Advanced Breast Cancer
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT03032406 ACTIVE NOT RECRUITING CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer
Abramson Cancer Center at Penn Medicine
NCT03323346 RECRUITING Phase II Trial of Disulfiram With Copper in Metastatic Breast Cancer
The Institute of Molecular and Translational Medicine, Czech Republic
NCT07074106 NOT YET RECRUITING TIL-Driven De-escalated Chemotherapy in Stage I-II TNBC
D'Or Institute for Research and Education
NCT05837455 RECRUITING NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer
Washington University School of Medicine
NCT05394285 RECRUITING A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Anti-tumor Treatment in Advanced Breast Cancer
Henan Cancer Hospital
NCT04480619 NOT YET RECRUITING Safety and Efficacy of Ga68-IAC PET/CT for Diagnosis and Clinical Management in Metastatic Breast Cancer Patients
Advanced Imaging Projects, LLC
NCT07067307 NOT YET RECRUITING Melatonin in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
Mansoura University
NCT06914440 RECRUITING Neoadjuvant SBRT Followed by Nab-Paclitaxel Combined With Toripalimab in HR+/HER2- Breast Cancer
Xijing Hospital
NCT07065435 RECRUITING RC48 Plus Bevacizumab or Pyrotinib in HER2-Positive Metastatic Breast Cancer After T-DXd Failure: A Phase II Study
The First Affiliated Hospital with Nanjing Medical University
NCT06953882 RECRUITING Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy
Yale University
NCT02436993 ACTIVE NOT RECRUITING Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab
University of California, Irvine
NCT06441890 RECRUITING BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
University of Illinois at Chicago
NCT04298086 ACTIVE NOT RECRUITING A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT02955394 ACTIVE NOT RECRUITING Preoperative Fulvestrant With or Without Enzalutamide in ER+/Her2- Breast Cancer
University of Colorado, Denver
NCT06026657 RECRUITING Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer
Margaret Gatti-Mays
NCT06113016 RECRUITING Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors
Jonsson Comprehensive Cancer Center
NCT02605486 ACTIVE NOT RECRUITING Palbociclib in Combination With Bicalutamide for the Treatment of AR(+) Metastatic Breast Cancer (MBC)
Memorial Sloan Kettering Cancer Center
NCT07047755 NOT YET RECRUITING Trastuzumab Rezetecan Plus Pertuzumab in the Neoadjuvant Treatment of HER2 Positive BC
Henan Cancer Hospital
NCT07047443 NOT YET RECRUITING SHR-1811 Combined With Carboplatin in the Treatment of Advanced Breast Cancer With HER2 Expression
Anhui Provincial Cancer Hospital
NCT06402435 RECRUITING SBRT, Chemotherapy, and AK112 Neoadjuvant Therapy for Luminal-type Breast Cancer
Hubei Cancer Hospital
NCT05595499 RECRUITING Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors
Jonsson Comprehensive Cancer Center
NCT03414658 ACTIVE NOT RECRUITING The AVIATOR Study: Trastuzumab and Vinorelbine With Avelumab OR Avelumab & Utomilumab in Advanced HER2+ Breast Cancer
Adrienne G. Waks
NCT04677816 RECRUITING Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
Wake Forest University Health Sciences
NCT03747120 ACTIVE NOT RECRUITING Neoadjuvant Her2-targeted Therapy and Immunotherapy With Pembrolizumab [IIT2018-04-MCARTHUR-NEOHP]
University of Texas Southwestern Medical Center
NCT07041437 NOT YET RECRUITING Study of SHR-A2102 Combined Other Antitumor Drugs in Advanced Breast Cancer
Fudan University
NCT06439693 RECRUITING The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
Dana-Farber Cancer Institute
NCT06580002 RECRUITING Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
University of California, Irvine
NCT06500208 RECRUITING Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC
Shanghai Jiao Tong University School of Medicine
NCT02238808 ACTIVE NOT RECRUITING A Study to See Whether Estrogen Can Slow the Growth of Some ER Positive Breast Cancers
AHS Cancer Control Alberta
NCT03831178 ACTIVE NOT RECRUITING Docosahexaenoic Acid (DHA) for Women With Breast Cancer in the Neoadjuvant Setting
AHS Cancer Control Alberta
NCT06665178 RECRUITING Genomic and Transcriptomic Predictors of Sequential SG Sensitivity After T-DXd in ER+/HER2-Low Metastatic Breast Cancer
British Columbia Cancer Agency
NCT06927180 RECRUITING SHR-A1811 Plus Pertuzumab in the Neoadjuvant Treatment of HER2 Positive BC
Henan Cancer Hospital
NCT06394661 ACTIVE NOT RECRUITING Serplulimab Plus Chemotherapy for Early-stage HR+/HER2- Breast Cancer
Henan Cancer Hospital
NCT02750358 ACTIVE NOT RECRUITING Feasibility Study of Adjuvant Enzalutamide for the Treatment of Early Stage AR (+) Triple Negative Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT06239194 RECRUITING Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
ModeX Therapeutics, An OPKO Health Company
NCT06555068 RECRUITING A Trial of HRS-6209 in Combination With Fulvestrant, Letrozole, HRS-8080, or HRS-1358 in Breast Cancer Patients
Jiangsu HengRui Medicine Co., Ltd.
NCT06568692 RECRUITING A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
Processa Pharmaceuticals
NCT05323955 ACTIVE NOT RECRUITING Secondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of Tucatinib
Carey Anders, M.D.
NCT06832202 RECRUITING A Phase II Study of HLX22 in Combination With Trastuzumab Deruxtecan in HER2-low, Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer Patients
Shanghai Henlius Biotech
NCT06150898 RECRUITING Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)
Jules Bordet Institute
NCT07019337 NOT YET RECRUITING Oral Metronomic Capecitabine Combined With Pyrotinib in ADC-treated HER2-positive Metastatic Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT07014410 RECRUITING Pyrotinib Combined With Dalpiciclib Combined With Letrozole in ER-positive and HER2-positive Advanced Breast Cancer
Zhejiang Cancer Hospital
NCT02788981 ACTIVE NOT RECRUITING Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast Cancer
University of Chicago
NCT05498155 ACTIVE NOT RECRUITING Study of Neoadjuvant Olaparib Monotherapy and Olaparib and Durvalumab Combination in HER2 Negative BRCAm Breast Cancer
AstraZeneca
NCT06993714 RECRUITING 3D-printed Biodegradable Breast Implants for Breast Restoration
Xijing Hospital
NCT06678048 RECRUITING Arsenous Acid for Refractory Triple-Negative Breast Cancer
Sun Yat-sen University
NCT05596409 ACTIVE NOT RECRUITING ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study
Stemline Therapeutics, Inc.
NCT07005882 NOT YET RECRUITING Hormonal Receptor (HR)-Positive HER2 Negative Breast Cancer Patients Treated With Preoperative ELacestrant and PULSAR Radiotherapy
Azienda Ospedaliero-Universitaria Careggi
NCT02546232 ACTIVE NOT RECRUITING Improved Breast Cancer Therapy (I-BCT-1) in the Neoadjuvant and Metastatic Setting
Oslo University Hospital
NCT06199895 RECRUITING Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Liu Huang
NCT04614194 RECRUITING Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib
University of Texas Southwestern Medical Center
NCT06677879 RECRUITING A Prospective Cohort Study of Proton and Photon Therapy for Left-sided Breast Cancer.
Shanghai Proton and Heavy Ion Center
NCT06049355 RECRUITING EMBRACE: Exercising Together
OHSU Knight Cancer Institute
NCT05455619 RECRUITING Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
SynDevRx, Inc.
NCT06638931 ACTIVE NOT RECRUITING Agnostic Therapy in Rare Solid Tumors
Instituto do Cancer do Estado de São Paulo
NCT06992336 RECRUITING Circulating Tumor DNA Guided Boost Therapy in Early Triple Negative Breast Patients With Residual Disease After Neoadjuvant Therapy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT05472792 RECRUITING Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
UNC Lineberger Comprehensive Cancer Center
NCT04140526 ACTIVE NOT RECRUITING Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
OncoC4, Inc.
NCT05982093 ACTIVE NOT RECRUITING Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer
SOLTI Breast Cancer Research Group
NCT03964532 ACTIVE NOT RECRUITING TALAVE: Induction Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer
Georgetown University
NCT06369831 RECRUITING HER2 Targeted Molecular Imaging in mBC Using 68Ga-ABS011
Abscint NV/SA
NCT04007770 ACTIVE NOT RECRUITING Acupuncture Pilot Study for Cancer-related Cognitive Function
Memorial Sloan Kettering Cancer Center
NCT04152499 ACTIVE NOT RECRUITING Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)
Klus Pharma Inc.
NCT05251714 ACTIVE NOT RECRUITING CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer
Treadwell Therapeutics, Inc
NCT06975462 NOT YET RECRUITING A Phase II Study of SHR-A1811 Combined With Radiotherapy in HER2-positive and HER2-low Breast Cancer Brain Metastases
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT06975475 NOT YET RECRUITING SHR-A1811 and THPy in First or Second Line for HER2 Positive Advanced Breast Cancer Brain Metastases
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT05463601 ACTIVE NOT RECRUITING Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06165419 RECRUITING Definitive Radiation for High-Risk Spine Metastases
Stony Brook University
NCT05319873 RECRUITING Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer
Jonsson Comprehensive Cancer Center
NCT02764541 ACTIVE NOT RECRUITING Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)
Dana-Farber Cancer Institute
NCT05190094 RECRUITING Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies.
International Cancer Research Group, United Arab Emirates
NCT06958445 ENROLLING BY INVITATION Prevention of Oral Mucositis and Improvement of Quality of Life for Patients With Breast Cancer Undergoing Adjuvant Radiotherapy
Taipei City Hospital
NCT02917421 ACTIVE NOT RECRUITING Accelerated Radiation Therapy (ART) to the Breast and Nodal Stations
Weill Medical College of Cornell University
NCT03946202 RECRUITING KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer
Institute of Cancer Research, United Kingdom
NCT06957379 ACTIVE NOT RECRUITING Sirolimus for Injection (Albumin-bound) in Combination With Endocrine Therapy for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Who Have Failed Standard Therapy
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT03971409 RECRUITING Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer
Laura Huppert, MD, BA
NCT06207734 RECRUITING Discontinuation of CDK4/6 Inhibitors in Patients With Metastatic HR Positive, HER2 Negative Breast Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT04503265 RECRUITING A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
AtlasMedx, Incorporated
NCT06837792 RECRUITING Trastuzumab Deruxtecan vs Endocrine Therapy in Low-HER2 HR+ Advanced Breast Cancer
Yonsei University
NCT06225284 RECRUITING Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients
National Taiwan University Hospital
NCT06950086 RECRUITING Study of TYK-00540 Tablets in Patients With Advanced Solid Tumors
TYK Medicines, Inc
NCT03366844 ACTIVE NOT RECRUITING Breast Cancer Study of Preoperative Pembrolizumab + Radiation
Stephen Shiao
NCT05535413 RECRUITING UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases
Hunan Cancer Hospital
NCT06188559 ACTIVE NOT RECRUITING A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer
Eisai Inc.
NCT04647916 ACTIVE NOT RECRUITING Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases
SWOG Cancer Research Network
NCT03449238 RECRUITING Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
Weill Medical College of Cornell University
NCT04837820 ACTIVE NOT RECRUITING The Effect of Acupuncture on Cancer-Related Cognitive Difficulties
Memorial Sloan Kettering Cancer Center
NCT03161353 ACTIVE NOT RECRUITING Chemotherapy-free Trastuzumab and Pertuzumab in HER2-positive Breast Cancer: FDG-PET Response-adapted Strategy.
MedSIR
NCT06067503 RECRUITING Biomarkers to Detect Endocrine Therapy Resistance
University of Wisconsin, Madison
NCT06048718 RECRUITING T-DXd Therapy for HER2-low Breast Cancer Patients With Brain Metastases
MedSIR
NCT05536128 RECRUITING Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitor
Seoul National University Hospital
NCT04296162 ACTIVE NOT RECRUITING Oral Vinorelbine or Capecitabine Combined With Trastuzumab as Adjuvant Treatment for Patients With Lymph Node Negative, HER-2 Positive and Small Tumor Size Breast Cancer (ORCHID)
Fudan University
NCT04892693 RECRUITING Talazoparib in Advanced Breast Cancer Patients With Homologous Recombinant Deficiency
Seoul National University Hospital
NCT06768268 ENROLLING BY INVITATION A Dose-Image Optimization Trial Evaluating Mannitol and Voluven as Adjuncts for Indocyanine Green
National Taiwan University Hospital
NCT03377387 ACTIVE NOT RECRUITING Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT05013255 RECRUITING Pioglitazone Therapy Targeting Fatigue in Breast Cancer
West Virginia University
NCT04680442 RECRUITING Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction
Population Health Research Institute
NCT04523857 RECRUITING ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer
Abramson Cancer Center at Penn Medicine
NCT04445844 ACTIVE NOT RECRUITING INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study
Mridula George, MD
NCT05770531 RECRUITING Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy
Vanderbilt-Ingram Cancer Center
NCT06908668 NOT YET RECRUITING Evaluate the Efficacy and Safety of Adebrelimab Combined With Chemotherapy With or Without Radiotherapy as Neoadjuvant Treatment for HER2-Negative Locally Advanced Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT03417544 ACTIVE NOT RECRUITING Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC
Nancy Lin, MD
NCT05095207 RECRUITING Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer
Icahn School of Medicine at Mount Sinai
NCT05252988 ACTIVE NOT RECRUITING Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib
Spanish Breast Cancer Research Group
NCT06811870 RECRUITING A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Breast Cancer Patients
Guangdong Provincial People's Hospital
NCT06902311 RECRUITING Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)
UNC Lineberger Comprehensive Cancer Center
NCT05297617 RECRUITING Deescalation of Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk
UNICANCER
NCT05664893 RECRUITING Study to Determine the Safety and Efficacy of Ribociclib in Combination With Hormone Therapy and Hypofractionated Radiotherapy in Breast Cancer, With Positive Hormone Receptors and Negative HER2 Status, in Newly Diagnosed, Not Immediately Operable Elderly Patient (CALHYS)
Centre Antoine Lacassagne
NCT06788197 NOT YET RECRUITING A Study of SHR-A1811 and Fulvestrant, With or Without HS-10352, in Locally Advanced or Metastatic Breast Cancer Patients
Henan Cancer Hospital
NCT06632405 NOT YET RECRUITING A Trial of Camrelizumab Plus Nab-paclitaxel and Levocetirizine in Metastatic or Recurrent TNBC
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT03568422 ACTIVE NOT RECRUITING CFI-402257 in Combination With Paclitaxel in Patients With Advanced/Metastatic HER2-Negative Breast Cancer
Canadian Cancer Trials Group
NCT05101096 ACTIVE NOT RECRUITING Study of Sacituzumab Govitecan (SG) in Japanese Participants With Advanced Solid Tumors
Gilead Sciences
NCT06890871 ENROLLING BY INVITATION Radiotherapy with Immunotherapy and Anti-Angiogenic Therapy for Advanced HER2-Negative Breast Cancer: a Single-Arm Study
Zhongnan Hospital
NCT05485766 RECRUITING Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer
Okayama University
NCT04768426 RECRUITING Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer
Stanford University
NCT05332561 RECRUITING Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)
German Cancer Research Center
NCT06775236 NOT YET RECRUITING Clinical Trial of SYS6010±SYH2051 Versus Chemotherapy in Advanced Breast Cancer and Other Solid Tumors
CSPC Megalith Biopharmaceutical Co.,Ltd.
NCT05296746 RECRUITING Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer
SOLTI Breast Cancer Research Group
NCT05816655 RECRUITING Comparison of Clinical Efficacy Between Letrozole + Ribociclib and Fulvestrant + Letrozole + Ribociclib in Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer
Korea University Guro Hospital
NCT06768931 RECRUITING Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer
Sun Yat-sen University
NCT02547987 ACTIVE NOT RECRUITING Neoadjuvant Carboplatin and Docetaxel in Triple Negative Breast Cancer
Mothaffar Rimawi
NCT04053322 ACTIVE NOT RECRUITING Durvalumab, With Olaparib and Fulvestrant in Advanced ER+, HER2- Breast Cancer Patients.
UNICANCER
NCT03632941 ACTIVE NOT RECRUITING A Study to Evaluate Concurrent VRP-HER2 Vaccination and Pembrolizumab for Patients With Breast Cancer
Herbert Lyerly
NCT04841148 RECRUITING Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer
Abramson Cancer Center at Penn Medicine
NCT02482376 ACTIVE NOT RECRUITING Preoperative Single-Fraction Radiotherapy in Early Stage Breast Cancer
Duke University
NCT03820141 ACTIVE NOT RECRUITING Durvalumab with Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer
The Methodist Hospital Research Institute
NCT03650894 ACTIVE NOT RECRUITING Nivolumab, Ipilimumab, and Bicalutamide in Human Epidermal Growth Factor (HER) 2 Negative Breast Cancer Patients
Providence Health & Services
NCT05918328 RECRUITING Comparing the Efficacy of Nab-PH+Pyrrolitinib and TCbHP in the Neoadjuvant Treatment of HER2 Positive BC
Henan Cancer Hospital
NCT02326974 ACTIVE NOT RECRUITING T-DM1+Pertuzumab in Pre-OP Early-Stage HER2+ BRCA
Dana-Farber Cancer Institute
NCT06193525 RECRUITING FUnctional Selection of Advanced Breast Cancer Patients for Talazoparib Treatment Using the REpair Capacity (RECAP) Test
Erasmus Medical Center
NCT05020860 RECRUITING Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
Baylor Breast Care Center
NCT03324425 ACTIVE NOT RECRUITING Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer
Baylor Breast Care Center
NCT03944434 ACTIVE NOT RECRUITING FACILE: FeAsibility of First-line RiboCIclib in OLdEr Patients with Advanced Breast Cancer
Fondazione Sandro Pitigliani
NCT06847555 RECRUITING Phase I-II Clinical Study of Taurine for External Use in the Prevention and Treatment of Acute Radiation Skin Injury
Shandong Cancer Hospital and Institute
NCT06842472 NOT YET RECRUITING PD-L1 Inhibitor + RT ± Ursodeoxycholic Acid in Recurrent/Metastatic HER2-Neg Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04990921 RECRUITING Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
University of Louisville
NCT06691594 NOT YET RECRUITING Neoadjuvant Treatment of Triple-Negative Breast Cancer with Stereotactic Radiotherapy, PD-1 Monoclonal Antibody, and Chemotherapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06450314 RECRUITING Decreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests.
UNICANCER
NCT06259929 RECRUITING NEOadjuvant Abemaciclib and GIredestrant TriaL in Patients with ER-positive, HER2-negative Early Breast Cancer
Fondazione Oncotech
NCT06642545 RECRUITING Efficacy and Safety Study of Disitamab Vedotin + RC148 vs. Albumin-Paclitaxone ± Toripalimab in HR-/HER2-low Breast Cancer
RemeGen Co., Ltd.
NCT04356209 RECRUITING Improving Theempowerment in Patients With Severe Breast Fibrosis Radio-induced Treated by Pravastatin : Benefit of e-PROs (Electronic " Patient Reported Outcome ") on Breast-related Quality of Life
Institut du Cancer de Montpellier - Val d'Aurelle
NCT05020574 RECRUITING Microbiome and Association With Implant Infections
University of California, San Francisco
NCT06819215 RECRUITING Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors
Zhejiang Yangli Pharmaceutical Technology Co., Ltd.
NCT05591547 ACTIVE NOT RECRUITING Evaluating the Safety and Efficacy of a Novel Accelerated Partial Breast Irradiation Regimen
Sanford Health
NCT05545150 ACTIVE NOT RECRUITING Volumetric Specimen Imager Device for the Intraoperative Imaging of Patients With Breast Carcinoma and Breast Ductal Carcinoma In Situ, The VIVID Study
Northwestern University
NCT06718933 RECRUITING Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis
Fudan University
NCT05301881 RECRUITING COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO Study
The Netherlands Cancer Institute
NCT03328026 ENROLLING BY INVITATION Combination Study of SV-BR-1-GM With Retifanlimab
BriaCell Therapeutics Corporation
NCT05388149 RECRUITING Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual Disease
University Health Network, Toronto
NCT05748834 RECRUITING Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
SCRI Development Innovations, LLC
NCT06793553 RECRUITING Induction Therapy of PTX+BV Followed by Atezolizumab+Nab-PTX for PD-L1+ TNBC
Japan Breast Cancer Research Group
NCT02752685 ACTIVE NOT RECRUITING Phase II Study of Pembrolizumab and Nab-paclitaxel in HER-2 Negative Metastatic Breast Cancer
NYU Langone Health
NCT06797622 NOT YET RECRUITING Heterogeneity of 68Ga-FAPI Uptake As Imaging Biomarker in T-DXd Treatment for Brain Metastasis of HER2 Positive Breast Cancer
Fudan University
NCT05475678 RECRUITING Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer
Zhenzhen Liu
NCT04902872 ACTIVE NOT RECRUITING Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors
Cybrexa Therapeutics
NCT06787339 NOT YET RECRUITING Capecitabine in Low Risk Triple Negative Breast Cancer
Fudan University
NCT06780748 RECRUITING Photo-medicine-Guided Dual Approach for Reoperation of Sentinel Lymph Nodes in Locally Recurrent Breast Cancer Patients
National Cancer Center, Korea
NCT04215146 ACTIVE NOT RECRUITING A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel - BRACELET-1 Study
Oncolytics Biotech
NCT04819243 RECRUITING PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study
Samsung Medical Center
NCT06757335 NOT YET RECRUITING A Phase I/II Trial to Evaluate Oral HP568 Tablets in Patients with ER+/HER2 Advanced Breast Cancer
Hinova Pharmaceuticals Inc.
NCT06750848 NOT YET RECRUITING Chidamide Combined With Angiogenesis Inhibitors and Fulvestrant for Advanced HR-positive, HER2-negative Breast Cancer
Jundong Wu
NCT06702618 NOT YET RECRUITING Evaluation of TQB3616 Capsules in a Phase II Clinical Trial for Recurrent/Metastatic Breast Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06470672 NOT YET RECRUITING Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer
Fudan University
NCT06276868 RECRUITING Darsilide Combined With AI, Trastuzumab and Patuzumab in the Neoadjuvant Treatment of HR+/HER2+ Breast Cancer
Henan Cancer Hospital
NCT06732336 RECRUITING HER2-PET Imaging in HER2-low Breast Cancers
Centre de recherche du Centre hospitalier universitaire de Sherbrooke
NCT06733233 NOT YET RECRUITING A Study Evaluating the Efficacy and Safety of De Trastuzumab (T-DXd) in Combination with Immunotherapy for the Neoadjuvant Treatment of HR-positive HER2 Low-expressing Chinese Patients with Early-stage Breast Cancer
Guangzhou Women and Children's Medical Center
NCT06516289 RECRUITING Neoadjuvant Treatment of gBRCA-Mutated HER2-Negative Breast Cancer With HRS-1167 and Famitinib ± Camrelizumab
Fudan University
NCT05974449 RECRUITING Lactobacillus Vaginalis Capsules for Treatment of Vulvovaginal Atrophy in Young Breast Cancer Patients
The First Affiliated Hospital with Nanjing Medical University
NCT06731153 NOT YET RECRUITING JAK1 Inhibitor Ivarmacitinib Reversing Immunotherapy Resistance in TNBC
Fudan University
NCT06727357 ACTIVE NOT RECRUITING Next Generation Sequencing-based "Oncochip" for Therapeutic Decision in Metastatic Breast Cancer. Study SHARP
European Institute of Oncology
NCT04985266 RECRUITING A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer
Royal Marsden NHS Foundation Trust
NCT04551495 ACTIVE NOT RECRUITING Neoadjuvant Study of Targeting ROS1 in Combination With Endocrine Therapy in Invasive Lobular Carcinoma of the Breast (ROSALINE)
Jules Bordet Institute
NCT06340230 RECRUITING SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer
Shengjing Hospital
NCT06401005 RECRUITING SBRT, Chemotherapy, and AK104 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC)
Hubei Cancer Hospital
NCT05165225 ACTIVE NOT RECRUITING Phase II Neoadjuvant Pyrotinib Combined with Neoadjuvant Chemotherapy in HER2-low-expressing and HR Positive Early or Locally Advanced Breast Cancer: a Single-arm, Non-randomized, Single-center, Open Label Trial
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT05891561 RECRUITING Short-course Trastuzumab, Pertuzumab with Taxanes in the Adjuvant Treatment of Early HER2-positive Breast Cancer
Shanghai Jiao Tong University School of Medicine
NCT06102824 RECRUITING Organoid-based Functional Precision Therapy for Advanced Breast Cancer
Guangdong Provincial People's Hospital
NCT05824975 RECRUITING A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
GI Innovation, Inc.
NCT06222879 RECRUITING Study of HRS-8080 or SHR-A2009 Combined With Anti-tumor Therapy in Patients With Unresectable or Metastatic Breast Cancer
Shandong Suncadia Medicine Co., Ltd.
NCT03934905 RECRUITING Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
Texas Tech University Health Sciences Center
NCT04879563 ACTIVE NOT RECRUITING Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project
Region Örebro County
NCT03971045 RECRUITING Pembrolizumab and Oral Metronomic Cyclophosphamide in Patients With Chest Wall Breast Cancer
European Institute of Oncology
NCT06452706 RECRUITING The Clinical Trial of TQB2102 for Injection Against Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT05262400 ACTIVE NOT RECRUITING A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors
Pfizer
NCT06439771 RECRUITING A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC
MediLink Therapeutics (Suzhou) Co., Ltd.
NCT06532812 RECRUITING TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer
Essen Biotech
NCT06677944 RECRUITING Preoperative Partial Breast Irradiation in Early-Stage Breast Cancer
Yonsei University
NCT06679387 RECRUITING "The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients"
Ain Shams University
NCT05911958 RECRUITING A Study of SHR-A1811 as Neoadjuvant Treatment for Patients With HR-Positive, Low HER2 Expression Breast Cancer
Henan Cancer Hospital
NCT06663748 NOT YET RECRUITING ARX788 in HER2-positive Metastatic Breast Cancer Patients
Henan Cancer Hospital
NCT06650748 NOT YET RECRUITING Multigene Risk Score Combined With Ki-67 Dynamic Assessment in Stratified Neoadjuvant Endocrine Therapy Treatment With or Without CDK4/6 Inhibitors in HR+/HER2- Breast Cancer
Peking University
NCT06656624 RECRUITING Efficacy and Safety of Ribociclib Combined With AI Versus Physician&Amp;#39;s Choice of Chemotherapy Sequential Endocrine Therapy in ER Middle-low-expression/HER2-negative Advanced Breast Cancer (Rachel)
The First Affiliated Hospital with Nanjing Medical University
NCT04899908 RECRUITING Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
Dana-Farber Cancer Institute
NCT06653972 NOT YET RECRUITING Efficacy and Safety of a Two-week Dosing Regimen of Vinorelbine Combined with Liposomal Doxorubicin in the Treatment of HER2-negative Advanced Breast Cancer
Wang Jiayu
NCT05620134 ACTIVE NOT RECRUITING Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer
Salubris Biotherapeutics Inc
NCT06568705 RECRUITING Hypofractionated Online Adaptive Radiotherapy of Breast Cancer
Peking Union Medical College Hospital
NCT05769010 RECRUITING Study of SHR-A1811 in HER2-expression Advanced Breast Cancer with Brain Metastases
Henan Cancer Hospital
NCT05594095 RECRUITING SNF Platform Study of HR+/ HER2-advanced Breast Cancer
Fudan University
NCT04913337 ACTIVE NOT RECRUITING Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
NGM Biopharmaceuticals, Inc
NCT06185972 RECRUITING Novel Magnetic Resonance Imaging-Guided Ultrasound-Stimulated Microbubble Radiation Treatment for Patients With Chest-Wall and Breast Cancer
Sunnybrook Health Sciences Centre
NCT05865990 ACTIVE NOT RECRUITING HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease
MedSIR
NCT06592625 NOT YET RECRUITING Neoadjuvant SHR-A1811 Plus Adebrelimab in HR Negative/Low & HER2 Low Breast Cancer Patients
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06598046 RECRUITING A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC
Henan Cancer Hospital
NCT05772390 RECRUITING Partial Breast Re-irradiation in Women in Women with Locally Recurrent Breast Cancer Previously Treated with Conservative Surgery and Whole Breast Irradiation
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT06342037 RECRUITING NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 Trial
The Netherlands Cancer Institute
NCT04539496 ACTIVE NOT RECRUITING A Phase I/II Study of XZP-3287 in Metastasis Solid Tumors
Sihuan Pharmaceutical Holdings Group Ltd.
NCT06578286 NOT YET RECRUITING ARX788 in HER2-positive Metastatic Breast Cancer Patients Who Were Previously Treated With T-DXd
Fudan University
NCT06471673 RECRUITING A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer
BriaCell Therapeutics Corporation
NCT06176534 RECRUITING Combination Followed by Maintenance Chemotherapy Versus CDK4/6 Inhibitor Combined With Endocrine Therapy for HR Low/HER2-negative Advanced Breast Cancer: a Prospective, Randomized, Open-label Phase Ⅱ Clinical Trial
Henan Cancer Hospital
NCT06561022 NOT YET RECRUITING Precision Treatment of HR+ HER2- Advanced Breast Cancer Based on SNF Molecular Subtyping
Fudan University
NCT06547476 NOT YET RECRUITING Chidamide and PD-1 Inhibitor Plus Anlotinib for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed
Guangdong Provincial People's Hospital
NCT06006390 RECRUITING CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT06543992 RECRUITING Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis
The First Affiliated Hospital with Nanjing Medical University
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NovaOnco Therapeutics Co., Ltd.
NCT03900637 ACTIVE NOT RECRUITING PersonaLized neoAdjuvant Strategy ER Positive and HER2 Negative Breast Cancer TO Increase BCS Rate
Seoul National University Hospital
NCT06508216 RECRUITING A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast Cancer
Gustave Roussy, Cancer Campus, Grand Paris
NCT06236269 RECRUITING HR+/HER2- Advanced or Metastatic Breast Cancer Patients Treated With Sacituzumab Govitecan
SOLTI Breast Cancer Research Group
NCT06510465 NOT YET RECRUITING Neoadjuvant Therapy With Weekly Utidelone Combined With Cisplatin for Patients With Breast Cancer (NeoURANIA)
RenJi Hospital
NCT04303988 RECRUITING A Phase II Study of Triple-negative Breast Cancer Brain Metastases.
Fudan University
NCT06435104 NOT YET RECRUITING Aromatherapy in the Treatment of Early Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06483386 NOT YET RECRUITING Pyrotinib and Subcutaneous Preparation of Trastuzumab Combined With Capecitabine Neoadjuvant Therapy for HER2+ Study of Breast Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT06481956 ENROLLING BY INVITATION T-DM1 Combined With CDK4/6 Inhibitor Ribociclib
Zheng Yabing
NCT06475443 NOT YET RECRUITING Efficacy of Pyrotinib Plus Capecitabine in HER2-positive MBC With Active Brain Metastases That Have Failed ADCs
Henan Cancer Hospital
NCT05187338 RECRUITING Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT06472583 RECRUITING Preoperative Immunotherapy Combined With Stereotactic Radiation Therapy Boost in the Treatment of HER2-negative Breast Cancer
Maria Sklodowska-Curie National Research Institute of Oncology
NCT06470633 NOT YET RECRUITING To Evaluate the Efficacy of Adebrelimab Combined With Chemotherapy After HIFU Induction Neoadjuvant Therapy HR+/HER2- Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT06470347 RECRUITING A Real-World Study of Pyrrolitinib Maleate Tablets for HER-2-Positive Early or Locally Advanced Breast Cancer After Adjuvant Trastuzumab Therapy
Zunyi Medical College
NCT06311695 RECRUITING Contrast-Enhanced Spectral Mammography (CESM)
European Institute of Oncology
NCT06458413 RECRUITING Utidelone Capsule Plus Capecitabine (CAP) for Metastatic Breast Cancer
Min Yan, MD
NCT05269381 RECRUITING Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Mayo Clinic
NCT05720260 RECRUITING Immunotherapy, Hormone Therapy, and AKT Inhibitor for Premenopausal ER Positive MBC
National Taiwan University Hospital
NCT04215003 RECRUITING A Clinical Trial of Breast Cancer Neo-adjuvant Therapy Based on Molecular Pathway in FUSCC
Fudan University
NCT02993198 ACTIVE NOT RECRUITING A Prospective Study of Breast Cancer Patients With Abnormal Strain Imaging
Northwestern University
NCT03815890 RECRUITING Pre-operative Trial for Breast Cancer With Nivolumab in Combination With Novel IO
The Netherlands Cancer Institute
NCT06433609 NOT YET RECRUITING Study of ADCs Combined With Adebrelimab in HER2-negative Advanced Breast Cancer
Beijing GoBroad Hospital
NCT06389006 RECRUITING To Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With Toripalimab Sequential Chemotherapy as Neoadjuvant Treatment in Patients With HR-positive, HER2-low Breast Cancer
RemeGen Co., Ltd.
NCT06427226 NOT YET RECRUITING Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity
Tanta University
NCT06411457 RECRUITING SHR-A1811 in Combination With Adebrelimab for the Treatment of HER2 Low-expressing Metastatic Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05396118 ENROLLING BY INVITATION Simultaneous Hyperpolarized [1-13C]Pyruvate and 18F-FDG PET/MRS in Cancer Patients
Rigshospitalet, Denmark
NCT06404697 RECRUITING Boost Irradiation to the Supraclavicular Area Among High Risk cN3c Breast Cancer Patients
Ruijin Hospital
NCT06404736 NOT YET RECRUITING QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer
Fudan University
NCT06404463 NOT YET RECRUITING QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk ER+/HER2- Breast Cancer
Fudan University
NCT05420779 RECRUITING A Study to Evaluate the Efficacy and Safety of TSL-1502 Capsules in Breast Cancer Patients With Germline BRCA Mutations
Jiangsu Tasly Diyi Pharmaceutical Co., Ltd.
NCT05033756 ACTIVE NOT RECRUITING Comprehensive Analysis of Predictors of the Treatment With Pembrolizumab and Olaparib in Patients With Unresectable or Metastatic HER2 Negative Breast Cancer and a Deleterious Germline Mutation or a Homologous Recombination Deficiency (COMPRENDO
Institut fuer Frauengesundheit
NCT03982485 ACTIVE NOT RECRUITING Combination Neoadjuvant Chemotherapy With or Without Apatinib for HER2 Negative Breast Cancer
RenJi Hospital
NCT04997941 ACTIVE NOT RECRUITING Higher Dose Preoperative taMOxifen in Premenopausal bREast Cancer Patients
Seoul National University Hospital
NCT05695313 RECRUITING Randomized Study Versus Placebo for the Prevention of Neurotoxicity Induced by Weekly PACLITAXEL
Centre Georges Francois Leclerc
NCT06339281 NOT YET RECRUITING A Multicenter Clinical Study of Apatinib Mesylate Combined With Doctor's Choice for Advanced Breast Cancer
Li Huiping
NCT06375707 RECRUITING Efficacy and Safety of Ribociclib in Combination With NSAI Versus Physician's Choice of Chemotherapy Sequential Endocrine Therapy in HR+/HER2- Advanced Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT05925257 RECRUITING Digital Health Intervention to Improve Health Care and Outcomes for Breast Cancer Patients
Coordinación de Investigación en Salud, Mexico
NCT06371807 NOT YET RECRUITING Trial for Treatment of High Risk BC With Two Sequences of Neoadjuvant Chemotherapy With Pembrolizumab
Fundacao Champalimaud
NCT06125834 RECRUITING Trastuzumab Emtansine (T-DM1) in HER2-positive Breast Cancer Patients With Progressive Disease After TKIs or HP Therapy
The First Affiliated Hospital with Nanjing Medical University
NCT05659056 RECRUITING Neoadjuvant Study With Pyrotinib and Trastuzumab and Abraxane in Patients With HER2-enriched Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT06149130 RECRUITING Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer
Tongji Hospital
NCT06362096 NOT YET RECRUITING A Multicenter, Prospective Study of Diarrhea Tolerance of Pyrotinib Combined With Trastumab and Taxane in the First-line Treatment of HER2-positive Advanced Breast Cancer
Huihua Xiong
NCT04469127 NOT YET RECRUITING A Phase I/II Multicenter, Open-Label Study of Lu-177-DOTAGA-IAC, for the Treatment of Angiogenic Breast Cancer Patients.
Advanced Imaging Projects, LLC
NCT06354114 NOT YET RECRUITING A Study to Evaluate the Efficacy and Safety in Subjects With Advanced Breast Cancer Treated With SYHX2011
CSPC Ouyi Pharmaceutical Co., Ltd.
NCT06341894 RECRUITING Efficacy and Safety of Dalpiciclib With Endocrine Therapy as Adjuvant Treatment in HR+/ HER2- Early Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT06341842 RECRUITING Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity
Fondazione IRCCS Policlinico San Matteo di Pavia
NCT06298084 RECRUITING Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd
Gustave Roussy, Cancer Campus, Grand Paris
NCT05986071 NOT YET RECRUITING I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers
Institut Paoli-Calmettes
NCT06328387 RECRUITING HCQ+ADC vs ADC in the Treatment of Advanced Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT04383275 RECRUITING Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS)
Fudan University
NCT05861271 RECRUITING Adjuvant Pyrotinib and Capecitabine For HER2 Positive Micro Invasive Breast Cancer
Fudan University
NCT06265025 RECRUITING GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors
GeneMedicine Co., Ltd.
NCT06227117 RECRUITING Neoadjuvant Study of DV in Combination Toripalimab or Sequence Chemotherapy in HR-negative, HER2 Low-expressing Breast Cancer
RemeGen Co., Ltd.
NCT05230810 RECRUITING Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.
Criterium, Inc.
NCT06176339 ACTIVE NOT RECRUITING Assessing the Clinical Utility of Adding Pentoxifylline to Neoadjuvant Chemotherapy Protocols in Breast Cancer Patients"
Mansoura University
NCT06308939 NOT YET RECRUITING Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial
Zhejiang Cancer Hospital
NCT06202261 RECRUITING A Study of TQB2930 for Injection Monotherapy or Combination Therapy in Patients With Recurrent/Metastatic Breast Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06297811 NOT YET RECRUITING Myeloprotection With Trilaciclib in Pan-cancer Population
Sun Yat-sen University
NCT03474822 RECRUITING Plasmodium Immunotherapy for Breast and Liver Cancers
CAS Lamvac Biotech Co., Ltd.
NCT06254066 NOT YET RECRUITING Adebrelimab Combined With Fluzoparib in HRD-positive HR +/HER2- Advanced Breast Cancer
Zhejiang Cancer Hospital
NCT06254690 RECRUITING The Dosing Regimen of Pyrotinib in HER2-positive Advanced First-line Breast Cancer: a Phase II Clinical Study
The First Affiliated Hospital with Nanjing Medical University
NCT05949541 RECRUITING Efficacy of Everolimus Combined With First-line Endocrine Therapy for HR+/HER2- SNF1-subtype Advanced Breast Cancer
Fudan University
NCT05205200 RECRUITING Immune Therapy in HR-positive/HER2-negative Metastatic Breast Cancer(ENIGMA)-BCTOP-L-M02
Fudan University
NCT05759546 RECRUITING PARP Inhibitor With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer
Fudan University
NCT05759572 RECRUITING Apatinib With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2- Advanced Breast Cancer
Fudan University
NCT06229067 NOT YET RECRUITING Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With Metronomic VEX in Advanced Triple-negative Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06169072 RECRUITING Sentinel Lymph Node Localisation With an Ultra-low Dose of Magtrace in Breast Cancer Patients
Vastra Gotaland Region
NCT03609047 ACTIVE NOT RECRUITING Adjuvant Palbociclib in Elderly Patients With Breast Cancer
European Organisation for Research and Treatment of Cancer - EORTC
NCT02965950 ACTIVE NOT RECRUITING The p53 Breast Cancer Trial
Haukeland University Hospital
NCT06165900 RECRUITING Stereotactic Radiotherapy Combined With Adebrelimab and TCb (Nab-paclitaxel + Carboplatin) in Neoadjuvant Treatment of TNBC
Shengjing Hospital
NCT06001086 RECRUITING A Phase II Clinical Study of Treatment With Disitamb Vedotin Plus Pyrotinib in HER2-positive Early Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT05451784 RECRUITING Treatment of Advanced or Metastatic Triple-negative Breast Cancer With Adoptive Therapy of PD1+ TILS
Fundacio Clinic Barcelona
NCT04920708 RECRUITING Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression
Royal Marsden NHS Foundation Trust
NCT06088056 NOT YET RECRUITING A Phase II Study of T-DXd Plus SRT in HER2-positive Breast Cancer Brain Metastases
Fudan University
NCT04172259 ACTIVE NOT RECRUITING ACHP-THP vs EC-THP as Neoadjuvant Therapy for HER2-positive EBC
Sun Yat-sen University
NCT04817540 RECRUITING Phase II Trial of Anti-HER2 Treatment in HER2-enriched Early Breast Cancer Identified by PAM50 (HER2E-PAM, PAMILIA Study)
Gangnam Severance Hospital
NCT05569811 ACTIVE NOT RECRUITING NeoadjuVAnt muLti-agENT Chemotherapy or Patritumab Deruxtecan With or Without endocrINE Therapy for High-risk HR+/HER2- Breast Cancer - VALENTINE Trial
SOLTI Breast Cancer Research Group
NCT06023277 NOT YET RECRUITING A Phase 1b/2 Clinical Trial to Evaluate the Safety and Efficacy of ConvitVax in Metastatic Breast Cancer
Jacinto Convit World Organization Inc.
NCT06000917 RECRUITING A Study of Neoadjuvant TCHpy(Pyrotinib ,Trastuzumab,Carboplatin and Paclitaxel)for ER+/HER2+ Breast Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT05983094 NOT YET RECRUITING Study of Utidelone Based Neoadjuvant Treatment on Early High-risk or Locally Advanced Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05983107 RECRUITING Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05979220 NOT YET RECRUITING Study of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line Chemotherapy
Shuangyue Liu
NCT05914831 RECRUITING Ultra-hypofractionated for Whole Breast Irradiation (WBI) Compared to Partial Breast Irradiation (PBI)
Oncology Institute of Vojvodina
NCT05824325 ACTIVE NOT RECRUITING Different Targeted Antibody-drug Conjugates For HER2 Ultra-low or No Expression Advanced Breast Cancer(GALAXY)
Fudan University
NCT03917082 ACTIVE NOT RECRUITING Limited Adjuvant Endocrine Therapy for Low Risk Breast Cancer
British Columbia Cancer Agency
NCT05763992 RECRUITING Targeting Triple Negative BREAst Cancer Metabolism With a Combination of Chemoimmunotherapy and a FASTing-like Approach in the Preoperative Setting: the BREAKFAST 2 Trial
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
NCT02315196 ACTIVE NOT RECRUITING Pegylated Liposomal Doxorubicin Hydrochloride and Carboplatin Followed by Surgery and Paclitaxel in Treating Patients With Triple Negative Stage II-III Breast Cancer
Rutgers, The State University of New Jersey
NCT05638594 RECRUITING Pyrotinib Combined With Trastuzumab, Dalpiciclib, Letrozole Versus TCbHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HR +/HER2 + Breast Cancer
Shengjing Hospital
NCT05732051 RECRUITING Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients
University Hospital, Akershus
NCT05766410 RECRUITING A Randomized Study Comparing the Immune Modulation Effect of Ribociclib, Palbociclib, and Abemaciclib in ER+/HER2- EBC
National Taiwan University Hospital
NCT05762900 RECRUITING Ultra-hypofractioNated Adjuvant Radiotherapy ± sImultaneous Integrated Boost for Low-risk Breast Cancer Patients
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05761470 RECRUITING Neoadjuvant Camrelizumab and Fluzoparib and Nab-paclitaxel in Early Breast Cancer With HRR Gene Mutation
Ying Lin
NCT05656131 RECRUITING Fluzoparib in Combination With or Without Camrelizumab for Homologous Recombinant Deficiency (HRD) HER2 Negative Advanced Breast Cancer
wang shusen
NCT05692674 RECRUITING A Prospective Phase II Study for Adjuvant Hypofractionated Intensity-modulated Proton Radiotherapy for Post Operative Breast Cancer With Implantation Reconstruction
Shanghai Proton and Heavy Ion Center
NCT03012100 ACTIVE NOT RECRUITING Multi-epitope Folate Receptor Alpha Peptide Vaccine, GM-CSF, and Cyclophosphamide in Treating Patients With Triple Negative Breast Cancer
Academic and Community Cancer Research United
NCT03428802 RECRUITING Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability
Rutgers, The State University of New Jersey
NCT05228951 RECRUITING Pyrotinib Maleate, Trastuzumab, SHR6390 and Letrozole in Combination for Stage II-III TPBC
Shengjing Hospital
NCT05519670 NOT YET RECRUITING A Phase 1b/2 Trial Evaluating Safety and Efficacy of CAPecitabine in Combination With Ni-rapaRIb in HER2-negative Advanced Breast canCEr
Institut Paoli-Calmettes
NCT04698252 RECRUITING Local Therapy for ER/PR-positive Oligometastatic Breast Cancer
Instituto do Cancer do Estado de São Paulo
NCT04486911 ACTIVE NOT RECRUITING Pyrotinib Maleate, CDK4/6 Inhibitor and Letrozole in Combination for Stage II-III TPBC: a Phase II Trial
Shengjing Hospital
NCT05431504 NOT YET RECRUITING The Efficacy and Safety of Dalpiciclib Plus Endocrine Therapy in HR-positive / HER2-negative Advanced Breast Cancer Patients With Visceral Crisis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04836156 RECRUITING Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for Human Epidermal Growth Factor Receptor 2 (HER2) Negative Early Breast Cancer Patients
Peking University People's Hospital
NCT04398914 ACTIVE NOT RECRUITING Pyrotinib, Trastuzumab, Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer
Shanghai Jiao Tong University School of Medicine
NCT05292742 RECRUITING Compare Continuation of Original Targeted Therapy With Trastuzumab Combined With Pyrotinib and Capecitabine as Postoperative Adjuvant Therapy in Non-pCR Patients With HER2 Positive Early Breast Cancer
Fujian Medical University Union Hospital
NCT04159818 RECRUITING Immune Induction Strategies to Improve Response to Immune Checkpoint Blockade in Triple Negative Breast Cancer (TNBC) Patients
The Netherlands Cancer Institute
NCT05232006 NOT YET RECRUITING PARP-inhibitor on Advanced Metastatic Breast Cancer in Germline PALB2 Mutations Carriers
Assistance Publique - Hôpitaux de Paris
NCT02603679 ACTIVE NOT RECRUITING Neoadjuvant Response-guided Treatment of Luminal B-type Tumors and Luminal A-type Tumors With Node Metastases
Thomas Hatschek
NCT04947280 RECRUITING Single Arm Phase II Study of Fractionated Stereotatic Radiation Therapy (FSRT) for Bone Metastases in Breast Cancer
Fudan University
NCT04922008 NOT YET RECRUITING Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS-C/D)
Fudan University
NCT03213041 RECRUITING Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer
Northwestern University
NCT04750122 RECRUITING Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for HER2 Positive Early Breast Cancer Patients
Peking University People's Hospital
NCT03591276 RECRUITING Phase 1b Study of Pegylated Liposomal Doxorubicin and Pembrolizumab in Endocrine-resistant Breast Cancer
Shaare Zedek Medical Center
NCT02592083 ACTIVE NOT RECRUITING Neoadjuvant Response-guided Treatment of Slowly Proliferating Hormone Receptor Positive Tumors
Thomas Hatschek
NCT03392233 RECRUITING Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors
RenJi Hospital
NCT02491697 ACTIVE NOT RECRUITING Immunotherapy Combined With Capecitabine Versus Capecitabine Monotherapy in Advanced Breast Cancer
The First People's Hospital of Changzhou
NCT05554354 TERMINATED Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06617455 TERMINATED Fezolinetant for the Improvement of Vasomotor Symptoms in Breast Cancer Patients Taking Endocrine Therapy, VENT Trial
University of Michigan Rogel Cancer Center
NCT02860000 COMPLETED Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer
Mayo Clinic
NCT03953326 TERMINATED HeartPhone Cancer Survivors Trial 2019
Penn State University
NCT03801369 TERMINATED AMTEC IIT: Phase 2 Multiarm Study in TNBC
Gordon Mills, MD, PhD
NCT05896566 COMPLETED A Window-of-Opportunity Trial of Giredestrant +/- Triptorelin vs. Anastrozole + Triptorelin in Premenopausal Patients With ER-positive/HER2-negative Early Breast Cancer
ETOP IBCSG Partners Foundation
NCT04059484 TERMINATED Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer
Sanofi
NCT03130439 TERMINATED Abemaciclib for Patients With Retinoblastoma-Positive, Triple Negative Metastatic Breast Cancer
Dana-Farber Cancer Institute
NCT05000294 SUSPENDED Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
University of Florida
NCT02530489 COMPLETED Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer
M.D. Anderson Cancer Center
NCT05269160 TERMINATED Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ)
Baylor College of Medicine
NCT07307911 COMPLETED Coenzyme Q10 for Neuroprotection in Paclitaxel-Induced Neuropathy
Damanhour University
NCT03301350 COMPLETED Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer
University of Wisconsin, Madison
NCT06975085 COMPLETED Understanding and Addressing Rejection of Personalized Breast Cancer Risk Information: Administrative Supplement Study
University of Colorado, Denver
NCT03101748 TERMINATED Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer
M.D. Anderson Cancer Center
NCT05101564 COMPLETED Umbrella Trial of Subtype-Targeted Therapies in ER+/HER2- Breast Cancer
Jennifer Lee Caswell-Jin
NCT03025035 COMPLETED Pembrolizumab in Combination With Olaparib in Advanced BRCA-mutated or HDR-defect Breast Cancer
Yuan Yuan
NCT02520063 COMPLETED Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer
University of Alabama at Birmingham
NCT05751668 SUSPENDED Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)
Alliance for Clinical Trials in Oncology
NCT04275661 COMPLETED Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery
Assiut University
NCT03781063 COMPLETED Evaluation of Lasofoxifene Versus Fulvestrant in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Sermonix Pharmaceuticals Inc.
NCT04570956 TERMINATED Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk
Mayo Clinic
NCT05070247 TERMINATED A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors
Takeda
NCT03765983 TERMINATED GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases
Dana-Farber Cancer Institute
NCT03289039 TERMINATED Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer
Dana-Farber Cancer Institute
NCT02668666 COMPLETED Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer
Oana Danciu, MD
NCT05280067 COMPLETED ZETAMET™ BONE GRAFT IN THE REPAIR OF BONE DEFECTS FROM METASTATIC BREAST CANCER IN VERTEBRAL BONES
Zetagen Therapeutics, Inc
NCT03056755 COMPLETED Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole, Based on Prior Endocrine Therapy, in Patients With PIK3CA Mutant, HR+, HER2- Advanced Breast Cancer Who Have Progressed on or After Prior Treatments
Novartis Pharmaceuticals
NCT04578106 TERMINATED Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy
Fundacio Clinic Barcelona
NCT03212170 COMPLETED FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer
University of Wisconsin, Madison
NCT03345420 COMPLETED Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer
University of Utah
NCT02806258 TERMINATED Comparing Sequential Neoadjuvant Treatment Including Chemotherapy and Accelerated Radiation Focused to the Tumor Bed vs Neoadjuvant Chemotherapy Alone
University Hospital, Grenoble
NCT06570811 COMPLETED Coenzyme Q10 and Chemotherapeutic Toxicity in Breast Cancer Patients
Damanhour University
NCT05963984 COMPLETED A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants
Carrick Therapeutics Limited
NCT06613516 WITHDRAWN Effect of Capivasertib on ctDNA in ER Positive Breast Cancer
Imperial College London
NCT03225547 TERMINATED Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer
University of Chicago
NCT04699630 COMPLETED A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer
SCRI Development Innovations, LLC
NCT03095352 COMPLETED Pembrolizumab With Carboplatin Compared to Carboplatin Alone in Breast Cancer Patients With Chest Wall Disease
Laura Huppert, MD, BA
NCT02760030 COMPLETED Endocrine Therapy Fulvestrant & Palbociclib or Aromatase Inhibitor Therapy in Treating Older Patients With Hormone Responsive Breast Cancer That Cannot Be Removed by Surgery
Ohio State University Comprehensive Cancer Center
NCT06851442 TERMINATED Clinical Trial of Evaluating TQB3912 Tablets Combined With Fulvestrant Injection±TQB3616 Capsules for Locally Advanced or Metastatic Hormone Receptor(HR)-Positive and Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT02654119 COMPLETED Cyclophosphamide, Paclitaxel, and Trastuzumab in Treating Stage I-II HER2/Neu Positive Breast Cancer After Surgery
University of Nebraska
NCT04603183 COMPLETED ABemaciclib, ET ± paclItaxel in aGgressive HR+/HER2- MBC trIaL
MedSIR
NCT05583110 TERMINATED Efficacy and Safety of the Combination of Trastuzumab Plus TUCAtinib Plus viNorelbine in Patients With HER2-positive Non-resectable Locally Advanced or Metastatic Breast Cancer
Spanish Breast Cancer Research Group
NCT06008158 SUSPENDED Evaluation of a Once Per Day Regimen of Accelerated Partial Breast Irradiation for Improved Breast Appearance in Pts w/Low Risk, Hormone Responsive Brst Ca
City of Hope Medical Center
NCT04188119 WITHDRAWN A Proof of Concept Window Trial of the IMmunological Effects of AveLumab and Aspirin in Triple-Negative Breast Cancer
The Christie NHS Foundation Trust
NCT05520723 COMPLETED Preventive stRategy for IMMU132-relatED AEs in TNBC or Luminal Breast Cancer- PRIMED
MedSIR
NCT02783690 COMPLETED A Trial of 15 Fraction vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy in Patients Requiring Regional Nodal Irradiation
Mayo Clinic
NCT05190770 COMPLETED A Study of Oleogel-S10 Gel for the Treatment of Radiation Dermatitis in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT06695039 COMPLETED Diagnostic Performance of [18F]FES PET/CT for Axillary LN Metastasis in ER-positive Breast Cancer
Asan Medical Center
NCT05180006 TERMINATED Impact of Neoadjuvant Immunotherapy in Early Stage Breast Cancer Before Standard Therapy
Gustave Roussy, Cancer Campus, Grand Paris
NCT05383170 COMPLETED A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers
Cytovation AS
NCT03624478 COMPLETED Hypofractionated Radiation Therapy in Treating Participants With Breast Cancer Before Surgery
Mayo Clinic
NCT02630693 COMPLETED Two Different Schedules of Palbociclib + Second Line Endocrine Therapy in Estrogen Receptor Positive, HER2 Neg Advanced/Metastatic Breast Cancer
Canadian Cancer Trials Group
NCT03284957 TERMINATED Phase 1/2 Study of Amcenestrant (SAR439859) Single Agent and in Combination With Other Anti-cancer Therapies in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer
Sanofi
NCT05954143 TERMINATED Trial of BDC-1001 +/- Pertuzumab in Subjects With HER2-Positive Metastatic Breast Cancer
Bolt Biotherapeutics, Inc.
NCT04024436 TERMINATED A Study of TAS-120 in Patients With Metastatic Breast Cancer
Taiho Oncology, Inc.
NCT03979508 TERMINATED Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer
Mayo Clinic
NCT04504916 TERMINATED A Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT02593175 COMPLETED Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC
M.D. Anderson Cancer Center
NCT03671330 COMPLETED Efficacy and Safety of Ribociclib in Pre- and Postmenopausal Chinese Women With HR Positive, HER2-negative, Advanced Breast Cancer.
Novartis Pharmaceuticals
NCT03620643 COMPLETED Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours
Royal Marsden NHS Foundation Trust
NCT03822468 COMPLETED Study of 2 Ribociclib Doses in Combination With Aromatase Inhibitors in Women With HR+, HER2- Advanced Breast Cancer
Novartis Pharmaceuticals
NCT04136912 TERMINATED 3-D Super Resolution Ultrasound Microvascular Imaging
UNC Lineberger Comprehensive Cancer Center
NCT05198843 TERMINATED Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body
National Cancer Institute (NCI)
NCT04659603 TERMINATED Tusamitamab Ravtansine Monotherapy and in Combination in Patients With CEACAM5-positive Advanced Solid Tumors
Sanofi
NCT04108858 TERMINATED Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer
National Cancer Institute (NCI)
NCT06703593 COMPLETED Prevention of Doxorubicin-induced Cardiotoxicity in Breast Cancer Patients
British University In Egypt
NCT06465368 COMPLETED A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
Pfizer
NCT04539938 COMPLETED A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer
Seagen, a wholly owned subsidiary of Pfizer
NCT04216472 TERMINATED Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN Alterations
M.D. Anderson Cancer Center
NCT04191382 TERMINATED Phase 2 Window Study of SAR439859 (Amcenestrant) Versus Letrozole in Post-menopausal Patients With ER+, HER2- Pre-operative Post-menopausal Primary Breast Cancer
Sanofi
NCT04249622 TERMINATED Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer
Mayo Clinic
NCT02958852 COMPLETED A Clinical Trial to Compare Efficacy and Tolerability of Atorvastatin in Addition to Endocrine Treatment With Focus on Mechanisms of Resistance to Endocrine Treatment (Fulvestrant/Aromatase Inhibitors) in Patients With Advanced Breast Cancer
Lund University Hospital
NCT03093350 COMPLETED TACTIC - TAA Specific Cytotoxic T Lymphocytes in Patients With Breast Cancer
Baylor College of Medicine
NCT03501979 TERMINATED Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD
University of Alabama at Birmingham
NCT05549505 COMPLETED A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery
Arvinas Inc.
NCT02423902 TERMINATED A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer
Alaunos Therapeutics
NCT07143097 COMPLETED Capecitabine as Maintenance Therapy vs Observation in Early-stage Triple-negative Breast Cancer
Beni-Suef University
NCT04505826 COMPLETED A Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast Cancer
Olema Pharmaceuticals, Inc.
NCT05259696 COMPLETED Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)
Palleon Pharmaceuticals, Inc.
NCT06155331 COMPLETED Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients
Tanta University
NCT04756765 WITHDRAWN Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancer
Stanford University
NCT02807597 TERMINATED Real-time Intraoperative Breast Cancer Visualization for Margin Assessment
Samuel Achilefu
NCT03568656 COMPLETED Study to Evaluate CCS1477 in Advanced Tumours
CellCentric Ltd.
NCT02409316 COMPLETED [18F]FES PET/CT in Endocrine Refractory Breast Cancer
University of Pennsylvania
NCT04224272 COMPLETED A Study of ZW25 (Zanidatamab) With Palbociclib Plus Fulvestrant in Patients With HER2+/HR+ Advanced Breast Cancer
Jazz Pharmaceuticals
NCT05678205 WITHDRAWN A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors
Artiva Biotherapeutics, Inc.
NCT04300790 COMPLETED Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients
MedSIR
NCT03862131 TERMINATED PROactive Evaluation of Function to Avoid CardioToxicity
Washington University School of Medicine
NCT04227327 TERMINATED Study Evaluating Abemaciclib + Aromatase Inhibitors in HR+, HER2- Advanced Breast Cancer Patients (HERMIONE-7)
University of Milano Bicocca
NCT06186700 COMPLETED Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer
Mansoura University
NCT05744375 TERMINATED Trastuzumab Deruxtecan in First-line HER2-positive Locally Advanced/MBC Patients Resistant to Trastuzumab+Pertuzumab
Spanish Breast Cancer Research Group
NCT07081581 COMPLETED Analgesic Effect of Serratus Plane Block With Adjuvant Agents in Breast Cancer Surgery
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
NCT05417451 COMPLETED Multi-Omics Study of the Effect and Mechanisms of Acupuncture on Psychoneurological Symptoms Among Breast Cancer Survivors
University of Illinois at Chicago
NCT03755141 COMPLETED Efficacy and Safety of Trastuzumab Biosimilar (Herzuma®) Plus Treatment of Physician's Choice (TPC) in Patients With HER-2 Positive Metastatic Breast Cancer
National Cancer Center, Korea
NCT04352777 COMPLETED Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer
Duke University
NCT04290897 COMPLETED Oxaloacetate for the Improvement of Cognitive Complaints in Stage 0-IIIA Breast Cancer Survivors
Jonsson Comprehensive Cancer Center
NCT04737265 COMPLETED Pilot Study of an NTproBNP Guided Strategy of Cardioprotection
Abramson Cancer Center at Penn Medicine
NCT03106415 COMPLETED Pembrolizumab and Binimetinib in Treating Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer
Mayo Clinic
NCT06087237 COMPLETED The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery
Mansoura University
NCT03248492 TERMINATED A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1)
Daiichi Sankyo
NCT03094052 COMPLETED Incidence and Severity of Diarrhea in Patients With HER2 Positive Breast Cancer Treated With Trastuzumab and Neratinib
University of California, San Francisco
NCT04420598 COMPLETED DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease
MedSIR
NCT05756166 TERMINATED Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer
Roswell Park Cancer Institute
NCT04720729 TERMINATED Chemotherapy Monitoring by ctDNA in HER2- Metastatic Breast Cancer
Institut Curie
NCT05243641 TERMINATED Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
M.D. Anderson Cancer Center
NCT06533722 COMPLETED Adaptive Therapy for Post-Second-Line Advanced Breast Cancer
Sun Yat-sen University
NCT04789096 TERMINATED Tucatinib Together With Pembrolizumab and Trastuzumab
Breast Cancer Trials, Australia and New Zealand
NCT03222856 COMPLETED Ph II Study of Pembrolizumab & Eribulin in Patients With HR+/HER2- MBC Previously Treated With Anthracyclines & Taxanes
MedSIR
NCT04542135 COMPLETED Sulindac and Breast Density in Women at Risk of Developing Breast Cancer
Alison Stopeck
NCT04251169 TERMINATED Pembrolizumab + Paclitaxel in HR+/HER2- Non-luminal (by PAM50) Advanced Breast Cancer After CDK4/6 Inhibitor Progression
SOLTI Breast Cancer Research Group
NCT04849364 TERMINATED Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer
Bryan Schneider, MD
NCT05054374 COMPLETED A Study of Mirdametinib on Its Own or in Combination With Fulvestrant in People With Solid Tumor Cancer
Memorial Sloan Kettering Cancer Center
NCT03188393 COMPLETED Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery
NRG Oncology
NCT04252859 TERMINATED [18F]Fluoroestradiol-PET/CT Imaging of Invasive Lobular Carcinoma
University of Utah
NCT02595905 COMPLETED Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases
National Cancer Institute (NCI)
NCT04754399 COMPLETED Cannabidiol (CBD) for Treatment of Aromatase Inhibitor-Associated Arthralgias
University of Michigan Rogel Cancer Center
NCT05618613 TERMINATED Study of Elacestrant in Combination With Onapristone in Patients With Advanced or Metastatic Breast Cancer
Context Therapeutics Inc.
NCT02632448 COMPLETED A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Esperas Pharma Inc.
NCT06214793 SUSPENDED Taletrectinib in Previously Treated Metastatic CDH1-mutated Invasive Lobular Cancer (ILC)
Megan Kruse, MD
NCT04418219 WITHDRAWN Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer
Thomas Jefferson University
NCT03219476 COMPLETED Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Node-Negative Breast Cancer
Medical College of Wisconsin
NCT05659563 COMPLETED Preoperative Window Opportunity Study With Giredestrant or Tamoxifen in Premenopausal Women With ER+/HER2[-] & Ki67≥10%
MedSIR
NCT03328884 COMPLETED Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients
MedSIR
NCT06938711 WITHDRAWN A Rollover Protocol of Elacestrant, in Combination With Onapristone, for Patients With ER+, PR+, HER2- Advanced or Metastatic Breast Cancer
Context Therapeutics Inc.
NCT04875806 TERMINATED A Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid Tumors
NextCure, Inc.
NCT04965688 TERMINATED Biology Guided Therapy for Breast Cancer for ER Positive
Inova Health Care Services
NCT04383210 TERMINATED Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Elevation Oncology
NCT05359783 COMPLETED Sentinel Node Localization and Staging with Low Dose Superparamagnetic Iron Oxide
Vastra Gotaland Region
NCT05137067 COMPLETED A Novel Approach for Alleviating the Side Effects of Chemotherapeutic Agents.
Optimal Health Research
NCT06257758 TERMINATED A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors
Valerio Therapeutics
NCT02206984 COMPLETED Endocrine Response in Women With Invasive Lobular Breast Cancer
Priscilla McAuliffe
NCT04499950 COMPLETED Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03747042 COMPLETED Letrozole in Post-Menopausal Patients with Operable Hormone-Sensitive Breast Cancer
University of Texas Southwestern Medical Center
NCT03058289 COMPLETED A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Intensity Therapeutics, Inc.
NCT03250676 COMPLETED Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast Cancer
Eisai Inc.
NCT05554211 WITHDRAWN Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage
Northwestern University
NCT02531932 COMPLETED Comparison of Single-Agent Carboplatin vs the Combination of Carboplatin and Everolimus for the Treatment of Advanced Triple-Negative Breast Cancer
Amy Tiersten
NCT03691493 COMPLETED Radiation Therapy, Palbociclib, and Hormone Therapy in Treating Breast Cancer Patients With Bone Metastasis
Emory University
NCT03774472 COMPLETED Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer
M.D. Anderson Cancer Center
NCT04432454 COMPLETED Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Sermonix Pharmaceuticals Inc.
NCT03703492 COMPLETED Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS
University of Wisconsin, Madison
NCT03760588 COMPLETED Prevention of Cardiac Dysfunction During Breast Cancer Therapy
Torbjorn Omland
NCT04079517 COMPLETED Karolinska Interventional Study of Mammograhic Density (Karisma-1)
Karolinska Institutet
NCT04796324 SUSPENDED Anti-tumor Effect of Ixabepilone in Metastatic Breast Cancer (mBC) Selected by the Ixabepilone DRP.
Allarity Therapeutics
NCT05539365 WITHDRAWN Dendritic Cell-Based Treatment Plus Immunotherapy for the Treatment of Metastatic or Unresectable Triple Negative Breast Cancer
Roswell Park Cancer Institute
NCT02694809 COMPLETED The PROMISE Study: Duavee in Women With DCIS
Northwestern University
NCT04294225 COMPLETED Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer
Mayo Clinic
NCT03562832 COMPLETED Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the 2X-121 DRP
Allarity Therapeutics
NCT06618014 COMPLETED Neoadjuvant Toripalimab Plus Docetaxel and Carboplatin in Patients With Localized TNBC (NeoTOP)
Sun Yat-sen University
NCT03518606 COMPLETED Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours
UNICANCER
NCT04440982 TERMINATED Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients
Lumicell, Inc.
NCT04603911 COMPLETED RCT Comparing ESPB Solutions in Breast Surgery
Tufts Medical Center
NCT03847311 COMPLETED Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients
University of Arizona
NCT02203552 COMPLETED Minocycline Hydrochloride in Reducing Chemotherapy Induced Depression and Anxiety in Patients With Stage I-III Breast Cancer
Ohio State University Comprehensive Cancer Center
NCT03950570 COMPLETED ORIN1001 in Patients with Advanced Solid Tumors and Relapsed Refractory Metastatic Breast Cancer
Orinove, Inc.
NCT04256941 TERMINATED Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study
M.D. Anderson Cancer Center
NCT03084536 COMPLETED PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
Washington University School of Medicine
NCT03997968 COMPLETED A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors
Cyteir Therapeutics, Inc.
NCT05500508 TERMINATED Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Aminex Therapeutics, Inc.
NCT02993159 COMPLETED Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast
Northwestern University
NCT05176080 TERMINATED Famitinib Plus SHR6390 and Endocrine Therapy in the Treatment of HR-positive, HER2-negative Advanced Breast Cancer
Henan Cancer Hospital
NCT05555251 TERMINATED BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors
BioInvent International AB
NCT06265077 COMPLETED Novel Preventive Approach Against Filgrastim-Induced Bone Pain in Cancer Patients
Noha Mansour
NCT04789668 COMPLETED Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases
M.D. Anderson Cancer Center
NCT03644186 COMPLETED To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)
ETOP IBCSG Partners Foundation
NCT03206203 COMPLETED Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer
Vanderbilt-Ingram Cancer Center
NCT04168528 COMPLETED Phase I/IIa Study of 68GaNOTA-Anti-MMR-VHH2 for PET/CT
Universitair Ziekenhuis Brussel
NCT02491983 COMPLETED Palbociclib in Combination With Fulvestrant or Letrozole in Patients With ER+, HER2- Advanced Breast Cancer
MedSIR
NCT04276493 COMPLETED Anti-HER2 Bispecific Antibody Zanidatamab (ZW25) Activity in Combination With Chemotherapy With/Without Tislelizumab
BeiGene
NCT02632045 COMPLETED Study of Efficacy of Ribociclib After Progression on CDK4/6 Inhibition in Patients With HR+ HER2- Advanced Breast Cancer
Melissa K Accordino
NCT04675827 TERMINATED De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade
Jules Bordet Institute
NCT02708680 COMPLETED Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In
Syndax Pharmaceuticals
NCT04493333 TERMINATED Vaginal Dehydroepiandrosterone (DHEA) in Postmenopausal Breast Cancer Survivors on Aromatase Inhibitors
University of Arkansas
NCT02675231 COMPLETED A Study of Abemaciclib (LY2835219) in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer
Eli Lilly and Company
NCT02317783 TERMINATED Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment
University of Utah
NCT03356860 COMPLETED Safety and Efficacy of Durvalumab Combined to Neoadjuvant Chemotherapy in Localized Luminal B HER2(-) and Triple Negative Breast Cancer.
Grand Hôpital de Charleroi
NCT05457842 TERMINATED A Study to Find the Best Dose of ASP5354 to Show Lymph Nodes in People With Breast Cancer or Melanoma During Surgery
Astellas Pharma Inc
NCT02339532 COMPLETED Neoadjuvant Phase II Trial in Patients With T1c Operable, HER2-positive Breast Cancer According to TOP2A Status
UNICANCER
NCT02229084 COMPLETED Vaccination of High Risk Breast Cancer Patients
University of Arkansas
NCT03227328 COMPLETED CDK4/6-inhibitor or Chemotherapy, in Combination with ENDOcrine Therapy, for Advanced Breast Cancer / KENDO
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT02980341 COMPLETED Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer
Daiichi Sankyo Co., Ltd.
NCT05177796 WITHDRAWN Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast Cancer
M.D. Anderson Cancer Center
NCT06654570 COMPLETED Effects of Vaginal Estrogen on Serum Estradiol During Aromatase Inhibitor Therapy in Breast Cancer Patients with Vulvovaginal Atrophy: a Prospective Trial
Helsinki University Central Hospital
NCT04307329 COMPLETED Monalizumab and Trastuzumab In Metastatic HER2-pOSitive breAst Cancer: MIMOSA-trial
The Netherlands Cancer Institute
NCT05488444 WITHDRAWN A Feasibility and Acceptability Pilot Study Evaluating a Patient-Specific Targeted Intervention Using Patient Navigators or Routine Clinical Care
M.D. Anderson Cancer Center
NCT03205761 COMPLETED Analysis of Olaparib Response in Patients With BRCA1 and/or 2 Promoter Methylation Diagnosed of Advanced Breast Cancer
Spanish Breast Cancer Research Group
NCT05012397 TERMINATED Milademetan in Advanced/Metastatic Solid Tumors
Rain Oncology Inc
NCT03409198 COMPLETED Phase IIb Study Evaluating Immunogenic Chemotherapy Combined with Ipilimumab and Nivolumab in Breast Cancer
Oslo University Hospital
NCT04899349 TERMINATED Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant
Novartis Pharmaceuticals
NCT03839823 COMPLETED Study to Compare the Combination of Ribociclib Plus Goserelin Acetate With Hormonal Therapy Versus Combination Chemotherapy in Premenopausal or Perimenopausal Patients With Advanced or Metastatic Breast Cancer
Novartis Pharmaceuticals
NCT02187991 COMPLETED Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer
US Oncology Research
NCT03872388 TERMINATED Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant Chemotherapy
M.D. Anderson Cancer Center
NCT02453737 COMPLETED A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca
Mayo Clinic
NCT02689427 COMPLETED Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer
M.D. Anderson Cancer Center
NCT03043794 TERMINATED Study of Stereotactic Radiotherapy for Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05700669 COMPLETED Study to Assess Safety and Efficacy of AsiDNA in Combination with Olaparib in Participants with Recurrent Solid Tumors
Valerio Therapeutics
NCT02681523 TERMINATED ALERT: A Phase II Study of Alternating Eribulin and Hormonal Therapy in Pre-treated ER+ve Breast Cancer.
Imperial College London
NCT05966584 TERMINATED A Study to Prevent Rash in People Starting Alpelisib for the Treatment of Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT02431676 COMPLETED Survivorship Promotion In Reducing IGF-1 Trial
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04123704 TERMINATED Sitravatinib in Metastatic Breast Cancer
Xiang Zhang
NCT02613416 COMPLETED Denosumab and MRI Breast Imaging
Alison Stopeck
NCT04946864 SUSPENDED A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer
Ascentage Pharma Group Inc.
NCT06065059 TERMINATED Study to Evaluate TNG348 Alone and With a PARP Inhibitor in Patients With BRCA 1/2 Mutant or HRD+ Solid Tumors
Tango Therapeutics, Inc.
NCT03530696 COMPLETED T-DM1 and Palbociclib for Metastatic HER2 Breast Cancer
University of Arizona
NCT05021900 COMPLETED Efficacy and Safety of Tenalisib (RP6530), in Patients With Locally Advanced or Metastatic Breast Cancer
Rhizen Pharmaceuticals SA
NCT03560531 COMPLETED A Study of ZN-c5 in Subjects With Breast Cancer
Zeno Alpha Inc.
NCT03127098 TERMINATED QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer
NantCell, Inc.
NCT05163106 COMPLETED Neoadjuvant Treatment of Locally-advanced Breast Cancer Patients With Ribociclib and Letrozole
University Hospital, Akershus
NCT02188745 COMPLETED ER Reactivation Therapy for Breast Cancer
Dartmouth-Hitchcock Medical Center
NCT02676986 COMPLETED Short-term Preoperative Treatment With Enzalutamide, Alone or in Combination With Exemestane in Primary Breast Cancer
Queen Mary University of London
NCT04862143 TERMINATED Pilot Decentralized Clinical Trial in Men and Pre and Post-menopausal Women With Breast Cancer and a Specific Mutation (PIK3CA) Treated With Alpelisib in Combination With Fulvestrant
Novartis Pharmaceuticals
NCT03395899 COMPLETED Pre-operative Immunotherapy Combination Strategies in Breast Cancer
Queen Mary University of London
NCT05163223 TERMINATED Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Patients With Breast Cancer
Aston Sci. Inc.
NCT00194714 COMPLETED Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab
University of Washington
NCT04408118 COMPLETED First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBC
MedSIR
NCT04129216 COMPLETED The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast Cancer
Johns Hopkins University
NCT04738292 TERMINATED Onapristone and Fulvestrant for ER+ HER2- Metastatic Breast Cancer After Endocrine Therapy and CDK4/6 Inhibitors (The SMILE Study)
University of Wisconsin, Madison
NCT05212701 WITHDRAWN To Assess Efficacy and Safety of Oral Reparixin in Patients With Fatigue and Locally Advanced / Metastatic Breast Cancer
Dompé Farmaceutici S.p.A
NCT04243837 TERMINATED LYT-100 in Patients With BCRL
PureTech
NCT02448420 COMPLETED Study of Palbociclib and Trastuzumab With Endocrine Therapy in HER2-positive Metastatic Breast Cancer
SOLTI Breast Cancer Research Group
NCT05850637 COMPLETED Evaluate the Effectiveness and Toxicity of Adjuvant Ultra-hypofractionated Radiotherapy for Breast Cancer
Prevent Senior Institute
NCT02540330 TERMINATED A Pre-Surgical PK Study of IM and Intraductally Delivered Fulvestrant
Atossa Therapeutics, Inc.
NCT03703466 COMPLETED A Study of Abemaciclib (LY2835219) With and Without Food in Participants With Metastatic Breast Cancer
Eli Lilly and Company
NCT05967286 WITHDRAWN Olaparib and Alpelisib for Treatment of Metastatic Breast Cancer, A ComboMATCH Treatment Trial
National Cancer Institute (NCI)
NCT03007979 COMPLETED Alternative Dosing Schedule of Palbociclib in Metastatic Hormone Receptor Positive Breast Cancer
Washington University School of Medicine
NCT02648477 COMPLETED Pembrolizumab and Doxorubicin Hydrochloride or Anti-Estrogen Therapy in Treating Patients With Triple-Negative or Hormone Receptor-Positive Metastatic Breast Cancer
City of Hope Medical Center
NCT04172597 TERMINATED A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies
Spectrum Pharmaceuticals, Inc
NCT05112536 COMPLETED Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer
G1 Therapeutics, Inc.
NCT03841747 WITHDRAWN Paclitaxel Plus Pembrolizumab vs. Paclitaxel Weekly in ER+ Luminal B Metastatic Breast Cancer
Queen Mary University of London
NCT05085002 TERMINATED A Study of Lerociclib in Participants With Advanced Breast Cancer
EQRx, Inc.
NCT04102436 WITHDRAWN Non-Viral TCR Gene Therapy
National Cancer Institute (NCI)
NCT03322215 TERMINATED HR+/HER2- Advanced Breast Cancer and Endocrine Resistance
Theodoros Foukakis
NCT03665285 COMPLETED A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors
NextCure, Inc.
NCT05689359 WITHDRAWN Evaluation of Hydroxychloroquine to Prevent CIPN
University of Arizona
NCT03321981 COMPLETED MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.
Merus B.V.
NCT03051659 COMPLETED A Randomized Phase II Study Of Eribulin Mesylate With or Without Pembrolizumab For Metastatic Hormone Receptor Positive Breast Cancer
Dana-Farber Cancer Institute
NCT03709082 TERMINATED Palbociclib in Estrogen Receptor Positive (ER+) Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
University of Kansas Medical Center
NCT03744715 TERMINATED A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib
Spectrum Pharmaceuticals, Inc
NCT04199520 WITHDRAWN Compare the Efficacy of Surgery Combined With Systemic Therapy and Pure Systemic Therapy in Breast Cancer Patients
Henan Cancer Hospital
NCT04268134 COMPLETED Altering Lipids for Tolerance of Aromatase Inhibitor Therapy
University of Michigan Rogel Cancer Center
NCT05703555 WITHDRAWN INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701
Erasmus Medical Center
NCT02536742 COMPLETED Palbociclib in Molecularly Characterized ER-positive/HER2-negative Metastatic Breast Cancer
ETOP IBCSG Partners Foundation
NCT02746328 WITHDRAWN Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass
GTx
NCT02954055 COMPLETED MEtronomic TrEatment Option in Advanced bReast cAncer
ETOP IBCSG Partners Foundation
NCT04927481 TERMINATED A Study of Mitoxantrone Hydrochloride Liposome Injection in Patients With Advanced HER2 Negative Breast Cancer
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT02971761 COMPLETED Pembrolizumab and Enobosarm in Treating Patients With Androgen Receptor Positive Metastatic Triple Negative Breast Cancer
City of Hope Medical Center
NCT03477396 COMPLETED Ribociclib and Aromatase Inhibitor in Treating Older Participants With Hormone Receptor Positive Metastatic Breast Cancer
City of Hope Medical Center
NCT03853707 COMPLETED Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer
City of Hope Medical Center
NCT04240106 COMPLETED Niraparib Plus Aromatase Inhibitors for Luminal-like(HER2-,ER+) and gBRCA or HDR+ Metastatic Breast Cancer (LUZERN)
MedSIR
NCT03326102 COMPLETED Oral Paclitaxel Efficacy Safety and PK in Recurrent and Metastatic Breast Cancer
Daehwa Pharmaceutical Co., Ltd.
NCT02456857 COMPLETED Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot Initiative
M.D. Anderson Cancer Center
NCT03878823 COMPLETED Safety and Pharmacokinetics of ODM-209
Orion Corporation, Orion Pharma
NCT02768337 TERMINATED Cambridge Brain Mets Trial 1
Cambridge University Hospitals NHS Foundation Trust
NCT03306472 COMPLETED A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer
Cambridge University Hospitals NHS Foundation Trust
NCT03312738 COMPLETED A Study of Everolimus Plus Exemestane in Chinese Postmenopausal Women With Estrogen Receptor Positive, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Non-steroidal Aromatase Inhibitor
Novartis Pharmaceuticals
NCT04596150 COMPLETED Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer
CytomX Therapeutics
NCT05315687 WITHDRAWN Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy
Emory University
NCT03422679 TERMINATED Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
Cellestia Biotech AG
NCT04805736 COMPLETED Microwave Ablation Combined With Camrelizumab in the Treatment of Early Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT03149549 TERMINATED PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors
CytomX Therapeutics
NCT04983238 COMPLETED Evaluation of Safety and Efficacy of Sodium Thiosulfate (BYON5667) Eye Drops to Reduce Ocular Toxicity in Cancer Patients Treated With SYD985
Byondis B.V.
NCT03674112 COMPLETED A Study to Evaluate Patient Preference and Satisfaction of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Participants With HER2-Positive Early Breast Cancer
Hoffmann-La Roche
NCT05932667 TERMINATED Milademetan and Fulvestrant in GATA3-mutant, ER+HER- Advanced or Metastatic Breast Cancer
Institut Curie
NCT03742986 COMPLETED Trial of Nivolumab With Chemotherapy as Neoadjuvant Treatment in Inflammatory Breast Cancer (IBC)
NYU Langone Health
NCT04714619 TERMINATED CB-103 Plus NSAI In Luminal Advanced Breast Cancer
MedSIR
NCT05363605 TERMINATED A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours
Fusion Pharmaceuticals Inc.
NCT03052634 COMPLETED A Study of RC48-ADC in Subjects With Advanced Breast Cancer
RemeGen Co., Ltd.
NCT03831711 COMPLETED 68-Ga-RM2 PET/MRI in Imaging Patients With Estrogen Receptor-Positive Breast Cancer
Andrei Iagaru
NCT02312622 COMPLETED Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer
Joel Neal
NCT06161792 TERMINATED Evaluate RCN3028 in Treatment of Drug-Induced VMS in Breast Cancer
Yung Shin Pharm. Ind. Co., Ltd.
NCT04222790 COMPLETED A Study of Monosialic Gangliosides to Prevent Albumin-bound Paclitaxel Neurotoxicity
Henan Cancer Hospital
NCT04690855 TERMINATED A Study to Evaluate TAlazoparib, Radiotherapy and Atezolizumab in gBRCA 1/2 Negative Patients With PD-L1+ Metastatic Triple Negative Breast Cancer
Mylin A. Torres, MD
NCT04150731 COMPLETED 16α-18F-fluor-17β-estradiol PET/CT for Visualisation of Estrogen Receptor Positive Liver Metastases From Breast Cancer
University of Aarhus
NCT03481998 COMPLETED A Study of SHR6390 in Combination With Letrozole or Anastrozole or Fulvestrant in Patients With HR Positive and HER2 Negative Advanced Breast Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT03054363 COMPLETED Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer
University of Colorado, Denver
NCT02127073 TERMINATED Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer
Montefiore Medical Center
NCT04149522 TERMINATED Evaluation of Mepitel Film® in Preventing Epidermitis in Patients Receiving Radiation Therapy for Breast Cancer
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
NCT04465097 COMPLETED Neoadjuvant Tucidinostat and Exemestane in Early Breast Cancer
First Affiliated Hospital, Sun Yat-Sen University
NCT03190967 TERMINATED T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
National Cancer Institute (NCI)
NCT04265274 WITHDRAWN Vinorelbine, Cisplatin, Disulfiram and Copper in CTC_EMT Positive Refractory Metastatic Breast Cancer.
National Cancer Institute, Slovakia
NCT03916068 TERMINATED Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation Therapy
Legacy Health System
NCT03803761 WITHDRAWN A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer
National Cancer Institute (NCI)
NCT05371860 WITHDRAWN Radiation Omission in Patients With HER2 Overexpressing Tumors With Pathologic Complete Response
Armando Giuliano
NCT03809988 COMPLETED PALbociclib Rechallenge in horMone Receptor-posItive/HER2- Negative Advanced Breast Cancer (PALMIRA)
MedSIR
NCT02585388 TERMINATED Addition of Aromatase at the Navelbine in Pretreated Metastatic Breast Cancer.
ARCAGY/ GINECO GROUP
NCT04190056 TERMINATED Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer
University of California, San Francisco
NCT04720664 TERMINATED Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer
Georgetown University
NCT03329378 TERMINATED Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast Cancer
Icahn School of Medicine at Mount Sinai
NCT02598557 COMPLETED Alternative Dosing of Exemestane Before Surgery in Treating Postmenopausal Patients With Stage 0-II Estrogen Positive Breast Cancer
National Cancer Institute (NCI)
NCT02614794 COMPLETED A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer
Seagen Inc.
NCT00455039 WITHDRAWN INST 0514C- Biologic Correlative Study: Trial of GW572016 in HER2 Overexpressing Breast Cancer Patients
University of New Mexico
NCT02637024 COMPLETED Trial of Radiation Fractionation Schedules for Once-a-Day Accelerated Partial Breast Irradiation
Ontario Clinical Oncology Group (OCOG)
NCT03018080 COMPLETED Pilot Study of Paclitaxel Plus Pembrolizumab in Metastatic HER2-Negative Breast Cancer
Wake Forest University Health Sciences
NCT04639245 TERMINATED Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer
Fred Hutchinson Cancer Center
NCT03602079 COMPLETED Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Klus Pharma Inc.
NCT04901299 WITHDRAWN Fulvestrant + Neratinib In Breast Cancer
Massachusetts General Hospital
NCT03454529 COMPLETED The Effect of Simvastatin on Breast Cancer Cell Growth in Women With Stage I-II Breast Cancer
Michael Simon
NCT03464942 COMPLETED Stereotactic Radiation and Immunotherapy in Patients With Advanced Triple Negative Breast Cancer
Peter MacCallum Cancer Centre, Australia
NCT05191004 WITHDRAWN Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC
Nuvation Bio Inc.
NCT03555877 COMPLETED Anti-hormonal Therapie With Ribociclib in HR-positive / HER2- Negative Metastatic Breast Cancer
GBG Forschungs GmbH
NCT03735680 COMPLETED A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
OncoNano Medicine, Inc.
NCT02067741 TERMINATED CR1447 in Endocrine Responsive-HER2neg and TN-ARpos Breast Cancer
Swiss Cancer Institute
NCT04896320 WITHDRAWN Tucatinib With Chemotherapy and Trastuzumab in Advanced Her-2-neu Overexpressing, Previously Treated Breast Cancer.
Providence Health & Services
NCT02673398 COMPLETED Neratinib in Treating Older Patients With Stage IV HER2-Positive Breast Cancer
City of Hope Medical Center
NCT04675450 WITHDRAWN NBP in Women With Metastatic Breast Cancer to Prevent Nab-paclitaxel Induced Toxic Neuropathy
Conjupro Biotherapeutics, Inc.
NCT04305236 TERMINATED Neo-Adjuvant Abemaciclib With Fulvestrant in Patients With ER/PR +HER Negative Breast Cancer
University of California, Irvine
NCT04190433 WITHDRAWN Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial
Mayo Clinic
NCT03988036 COMPLETED A Study With Pembrolizumab in Combination With Dual Anti-HER2 Blockade With Trastuzumab and Pertuzumab in Early Breast Cancer Patients With Molecular HER2-enriched Intrinsic Subtype (Keyriched-1)
West German Study Group
NCT02526498 COMPLETED Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery
Rutgers, The State University of New Jersey
NCT04752059 COMPLETED Phase II Study of T-DX in HER2-positive Breast Cancer Brain Metastases
Medical University of Vienna
NCT02408770 COMPLETED Breast Cancer - Anti-Progestin Prevention Study 1
Manchester University NHS Foundation Trust
NCT02891759 COMPLETED Compare Outcomes Between Two Acellular Dermal Matrices
Washington University School of Medicine
NCT03321929 COMPLETED Intraoperative Detection of Residual Cancer in Breast Cancer
Lumicell, Inc.
NCT05412446 COMPLETED 99mTc-ADAPT6 SPECT-based Non-invasive Quantification of HER2-expression in Breast Cancer With Metastatic Lymph Nodes
Tomsk National Research Medical Center of the Russian Academy of Sciences
NCT03112590 COMPLETED Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT04189263 TERMINATED BREADS: Breast Adjuvant Diet Study
Farin Amersi
NCT03065621 COMPLETED Neoadjuvant Biomarker ResearcH Study of Palbociclib Combined With Endocrine Therapy in Estrogen Receptor Positive/HER2 Negative Breast CAncer (NeoRHEA)
Jules Bordet Institute
NCT05812326 COMPLETED PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT02322814 TERMINATED A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread
Hoffmann-La Roche
NCT03642990 TERMINATED NR in Chemo-induced Peripheral Neuropathy
Donna Hammond, PhD
NCT04836520 COMPLETED SHR6390 Combined With Anastrozole for Preoperative Treatment of Breast Cancer.
Tianjin Medical University Cancer Institute and Hospital
NCT03025880 COMPLETED Trial to Evaluate Efficacy and Safety of Pembrolizumab and Gemcitabine in HER2-negative ABC
Spanish Breast Cancer Research Group
NCT05079360 WITHDRAWN Efficacy Evaluation of Sabizabulin Monotherapy Versus Active Control for Treatment of ER+HER2- Metastatic Breast Cancer
Veru Inc.
NCT02970500 TERMINATED Effect of Methylphenidate on Cancer-related Cognitive Impairment
CHU de Quebec-Universite Laval
NCT04826016 WITHDRAWN POL6326 (Balixafortide) Plus Nab-paclitaxel or Eribulin in Patients With HER2-negative Advanced Breast Cancer
MedSIR
NCT05298696 COMPLETED Efficacy of Cilostazol in Prevention of Peripheral Neuropathy
Mansoura University
NCT02894398 COMPLETED Study in Women With Advanced Breast Cancer Receiving Palbociclib With AI or Fulvestrant
iOMEDICO AG
NCT05351021 COMPLETED Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients
Mansoura University
NCT04477616 COMPLETED Injection Regimen Trial of PEG-rhG-CSF During Breast Cancer Chemotherapy
The First Affiliated Hospital with Nanjing Medical University
NCT03931551 TERMINATED Olaparib+Trastuzumab in HER2[+],Breast Cancer Susceptibility Gene (BRCA) Mutated Advanced Breast Cancer
MedSIR
NCT02314156 COMPLETED Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy
Northwestern University
NCT02990845 TERMINATED Pembrolizumab and Exemestane/ Leuprolide in Premenopausal HR+/ HER2- Locally Advanced or Metastatic Breast Cancer
National Taiwan University Hospital
NCT03367689 TERMINATED A Two-stage Simon Design Phase II Study for Non-BRCA MBC Patients With HRD Treated With Olaparib Single Agent
MedSIR
NCT02479997 COMPLETED Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer Patients
National Cancer Center, Korea
NCT02401347 COMPLETED Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors
Melinda Telli
NCT04366713 COMPLETED A Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib
Puma Biotechnology, Inc.
NCT04588935 COMPLETED Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer
State Institution "Republican Scientific and Practical Center" Cardiology, Belarus
NCT04436744 COMPLETED A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Giredestrant Plus Palbociclib Compared With Anastrozole Plus Palbociclib for Postmenopausal Women With Estrogen Receptor-Positive and HER2-Negative Untreated Early Breast Cancer (coopERA Breast Cancer)
Hoffmann-La Roche
NCT03732391 COMPLETED Phase 2 Study of Pembrolizumab+Carboplatin in Breast Related Cancer Antigens-related Metastatic Breast Cancer (PEMBRACA)
CORTESI LAURA
NCT02658812 TERMINATED Talimogene Laherparepvec in Treating Patients With Recurrent Breast Cancer That Cannot Be Removed by Surgery
M.D. Anderson Cancer Center
NCT02652923 COMPLETED Contrast Ultrasound Detection of Sentinel Lymph Nodes
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT03430479 COMPLETED Anti PD-1 Antibody With Radiation Therapy in Patients With HER2-negative Metastatic Breast Cancer
Kyoto Breast Cancer Research Network
NCT02393248 TERMINATED Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)
Incyte Corporation
NCT03666819 WITHDRAWN Carbon Dioxide Fractional Laser in Treating Participants With Stage 0-III Hormone Receptor-Positive Breast Cancer With Vulvovaginal Atrophy
Mayo Clinic
NCT02438358 COMPLETED Feasibility Study of Intraoperative Imaging in Breast Cancer
Lumicell, Inc.
NCT02440230 COMPLETED Safety of OFS Combined With AI Endocrine Therapy in Chinese Premenopausal Breast Cancer Patients
Shanghai Jiao Tong University School of Medicine
NCT05233696 WITHDRAWN Radiotherapy in Combo With Chemo and Immunotherapy in Patients With PD-L1 Positive Metastatic TNBC
University of Colorado, Denver
NCT02643303 COMPLETED A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers
Ludwig Institute for Cancer Research
NCT02657889 COMPLETED Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancer
Tesaro, Inc.
NCT03735966 COMPLETED Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Docetaxel and Carboplatin in HER2 Positive Breast Cancer Patients.
Henan Cancer Hospital
NCT03386162 TERMINATED SAFIR-PI3K A Phase II Randomized Maintenance Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy in PIK3CA Mutated Advanced Breast Cancer
UNICANCER
NCT03344536 COMPLETED A Study of Debio 1347 Plus Fulvestrant in Patients With Metastatic Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT05206656 COMPLETED Safety and Efficacy of Eribullin or Eribulin Combined With Anlotinib in Metastatic Breast Cancer
Hunan Cancer Hospital
NCT04538833 WITHDRAWN GM1 in the Treatment of Neurotoxicity Induced by Albumin-bound Paclitaxel
Henan Cancer Hospital
NCT03383679 COMPLETED Study on Androgen Receptor and Triple Negative Breast Cancer
UNICANCER
NCT04871854 COMPLETED Evaluating Tocilizumab for Sever COVID-19 Infection in Breast Cancer vs. Non Cancer Pateints
Beni-Suef University
NCT04142060 TERMINATED Targeting the PAM50 Her2-Enriched Phenotype With Enzalutamide in Hormone Receptor-Positive/Her2-Negative Metastatic BC
SOLTI Breast Cancer Research Group
NCT04676516 COMPLETED A Phase II Window of Opportunity Trial of PRMT5 Inhibitor, GSK3326595, in Early Stage Breast Cancer
Ottawa Hospital Research Institute
NCT04460430 TERMINATED Targeting EGFR/ERBB2 With Neratinib in Hormone Receptor (HR)-Positive/HER2-negative HER2-enriched Advanced/Metastatic Breast Cancer
SOLTI Breast Cancer Research Group
NCT02448771 COMPLETED A Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer
Dana-Farber Cancer Institute
NCT02910219 COMPLETED Diarrhea Prevention and Prophylaxis With Crofelemer in HER2 Positive Breast Cancer Patients
Sandra Swain
NCT02730130 COMPLETED Study to Assess the Efficacy of Pembrolizumab Plus Radiotherapy in Metastatic Triple Negative Breast Cancer Patients
Memorial Sloan Kettering Cancer Center
NCT02806050 COMPLETED Palbociclib and FES PET
University Medical Center Groningen
NCT03947151 COMPLETED Efficacy and Tolerance of an Ovarian Stimulation Protocol Combining Follicle Stimulating Hormone (FSH) and Degarelix Acetate in Female Candidates for Fertility Preservation Before Chemotherapy for Breast Cancer
Assistance Publique - Hôpitaux de Paris
NCT02370238 COMPLETED A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer
Dompé Farmaceutici S.p.A
NCT04170465 COMPLETED Role of Adding Metformin to Neoadjuvant Chemotherapy in Patients With Breast Cancer (METNEO)
Damanhour University
NCT02203513 TERMINATED A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer
National Cancer Institute (NCI)
NCT02871791 COMPLETED Palbociclib With Everolimus + Exemestane In BC
Dana-Farber Cancer Institute
NCT03394027 COMPLETED ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma
National Cancer Institute (NCI)
NCT02457910 TERMINATED Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer
Vanderbilt-Ingram Cancer Center
NCT02506556 COMPLETED Phosphatidylinositol 3-kinase (PI3K) Alpha iNhibition In Advanced Breast Cancer
Peter MacCallum Cancer Centre, Australia
NCT04075604 COMPLETED A Study of Neoadjuvant Nivolumab + Palbociclib + Anastrozole in Post-Menopausal Women and Men With Primary Breast Cancer
Bristol-Myers Squibb
NCT02657343 COMPLETED An Open-Label, Phase Ib/II Clinical Trial Of Cdk 4/6 Inhibitor, Ribociclib (Lee011), In Combination With Trastuzumab Or T-Dm1 For Advanced/Metastatic Her2-Positive Breast Cancer.
Dana-Farber Cancer Institute
NCT03147040 TERMINATED AssessinG Efficacy of Carboplatin and ATezOlizumab in Metastatic Lobular Breast Cancer
The Netherlands Cancer Institute
NCT02826512 TERMINATED A Feasibility Study of Niraparib for Advanced, BRCA1-like, HER2-negative Breast Cancer Patients
The Netherlands Cancer Institute
NCT05227131 WITHDRAWN Margetuximab Plus Tucatinib and Capecitabine in HER2-positive Metastatic Breast Cancer
MedSIR
NCT02282345 COMPLETED Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer
M.D. Anderson Cancer Center
NCT05063604 TERMINATED Antidepressant Efficacy of Psychotherapy and Citalopram in Patients With Breast Cancer and Major Depression
Hospital Universitari de Bellvitge
NCT02562612 WITHDRAWN Study of SM-88 in Advanced Cancers
Tyme, Inc
NCT04512261 WITHDRAWN TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases
Reva Basho
NCT03584009 TERMINATED A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy
Hoffmann-La Roche
NCT03291886 COMPLETED Phase 2 Study of KHK2375 in Subjects With Advanced or Recurrent Breast Cancer
Kyowa Kirin Co., Ltd.
NCT03184090 COMPLETED Molecular Mechanisms of Resistance and Sensitivity to Palbociclib Re-challenge in ER+ mBC
MedSIR
NCT02379247 COMPLETED BYL719 and Nab-Paclitaxel in Locally Recurrent or Metastatic HER-2 Negative Breast Cancer
Priyanka Sharma
NCT03874325 TERMINATED Aromatase Inhibitor and Durvalumab in Postmenopausal Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT04351230 WITHDRAWN T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer
Academic and Community Cancer Research United
NCT03948477 COMPLETED Pantoprazole Prophylaxis Against Delayed CINV for Patients Receiving Breast Cancer Chemotherapy
University of Auckland, New Zealand
NCT02789657 COMPLETED Neoadjuvant Therapy in Clinical Stage I-III HER2-positive Breast Cancer.
Brown University
NCT02536794 COMPLETED MEDI4736 and Tremelimumab in Treating Patients With Metastatic HER2 Negative Breast Cancer
Northwestern University
NCT03787303 TERMINATED Study of Euthyroid Hypothyroxinemia in Metastatic Breast Carcinoma
Aultman Health Foundation
NCT02698891 COMPLETED Avoiding Growth Factor During Paclitaxel Treatment in Breast Cancer
Dana-Farber Cancer Institute
NCT05359874 WITHDRAWN Improvement of the Operative Outcome in Patients With Primary VEGF + Unifocal Breast Cancer or DCIS Through the Intraoperative Visualization of the Tumor Using Molecular Imaging and Bevacizumab-IRDye-800CW
Technical University of Munich
NCT03630809 TERMINATED Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1
H. Lee Moffitt Cancer Center and Research Institute
NCT02897050 SUSPENDED Trial of Neoadjuvant Docetaxel ± Metronomic Capecitabine/CTX Followed by FEC in Women With Operable Triple Negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT03628066 COMPLETED Biological and Clinical Effects of Palbociclib With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Breast Cancer
NSABP Foundation Inc
NCT02771353 COMPLETED The HeartSpare Plus 1B Trial
Royal Marsden NHS Foundation Trust
NCT02850419 WITHDRAWN Heat-Activated Target Therapy of Local-Regional Relapse in Breast Cancer Patients
Imunon
NCT04903652 COMPLETED Pyrotinib Maleate Combined With Vinorelbine in the Treatment of HER2-positive Advanced Breast Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT03045653 COMPLETED Efficacy of High Dose Tamoxifen to Advanced Hormone Receptor-High Expressed Breast Cancer
Sun Yat-sen University
NCT02978716 TERMINATED Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC)
G1 Therapeutics, Inc.
NCT02384239 COMPLETED A Study of Palbociclib in Combination With Fulvestrant or Tamoxifen as Treatment for Metastatic Breast Cancer
University of California, San Francisco
NCT02400567 COMPLETED Efficacy of Letrozole + Palbociclib Combination as Neoadjuvant Treatment of Stage II-IIIA PAM 50 ROR-defined Low or Intermediate Risk Luminal Breast Cancer, in Postmenopausal Women
UNICANCER
NCT02659514 COMPLETED Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer
Spectrum Pharmaceuticals, Inc
NCT02729701 COMPLETED Pilot Study of the Effect of Duavee® on Benign Breast Tissue Proliferation
University of Kansas Medical Center
NCT03180294 COMPLETED Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer
NRG Oncology
NCT04856475 WITHDRAWN Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast Cancer
Jules Bordet Institute
NCT02387099 COMPLETED Dose EScalation Induction of EvERolimus
GBG Forschungs GmbH
NCT04541290 COMPLETED Tacrolimus as Treatment of Breast Cancer-Related Lymphedema
Odense University Hospital
NCT02418689 COMPLETED Poziotinib in Patients With HER2+ Recurrent Stage IV BC Who Have Received at Least 2 Prior HER2-directed Regimens
Hanmi Pharmaceutical Company Limited
NCT02296801 COMPLETED A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer
NSABP Foundation Inc
NCT03608865 COMPLETED Durvalumab (MEDI4736) and Tremelimumab in Hormone Receptor-positive, Hypermutated Metastatic Breast Cancer Identified by Whole Exome Sequencing
Yonsei University
NCT03316586 COMPLETED A Phase II Study of Nivolumab in Combination With Cabozantinib for Metastatic Triple-negative Breast Cancer
Dana-Farber Cancer Institute
NCT02536339 COMPLETED A Study of Pertuzumab With High-Dose Trastuzumab for the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (MBC) With Central Nervous System (CNS) Progression Post-Radiotherapy
Genentech, Inc.
NCT04143282 COMPLETED Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment
Hager salah el din
NCT03012477 COMPLETED CISPLATIN + AZD-1775 In Breast Cancer
Dana-Farber Cancer Institute
NCT04038489 WITHDRAWN COX Inhibition and Biomarkers During Neoadjuvant Chemoendocrine Therapy for ER+, HER2- Stage I-III Breast Cancer
University of Virginia
NCT03342417 TERMINATED Combination of Nivolumab and Ipilimumab in Breast, Ovarian and Gastric Cancer Patients
ExcellaBio LLC
NCT03499353 TERMINATED Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
Pfizer
NCT03184558 TERMINATED Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With TNBC
BerGenBio ASA
NCT04298918 TERMINATED A Study Evaluating the Safety and Efficacy of Venetoclax in Combination With Trastuzumab Emtansine in Patients With Previously Treated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Hoffmann-La Roche
NCT04200482 COMPLETED Lifestyle Program (Scalable Nutrition and Physical Activity) for the Improvement of Nutrition and Physical Activity in Stage 0-III Breast Cancer Survivors
Fred Hutchinson Cancer Center
NCT03890744 COMPLETED ModraDoc006/r in Patients With Breast Cancer
Modra Pharmaceuticals
NCT03078751 COMPLETED Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer
Novartis Pharmaceuticals
NCT02366130 COMPLETED Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer
M.D. Anderson Cancer Center
NCT03940248 WITHDRAWN Proton Accelerated Partial Breast Irradiation
University of Cincinnati
NCT02404506 TERMINATED Eribulin as 1st Line Treatment in Elderly Patients With Advanced Breast Cancer
Swiss Cancer Institute
NCT02833766 TERMINATED Anti-EGFR-immunoliposomes Loaded With Doxorubicin in Patients With Advanced Triple Negative EGFR Positive Breast Cancer
Swiss Cancer Institute
NCT02907918 TERMINATED Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer
Washington University School of Medicine
NCT02742051 COMPLETED A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT03894007 TERMINATED Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer
Renske Altena
NCT02988986 COMPLETED TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast Cancer
The Methodist Hospital Research Institute
NCT03931928 COMPLETED Genotype and Phenotype Guided Supplementation of TAMoxifen Standard Therapy With ENDOXifen in Breast Cancer Patients
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
NCT03139851 COMPLETED Evaluation of Pembrolizumab in Lymphopenic Metastatic Breast Cancer Patients Treated With Metronomic Cyclophosphamide
Centre Leon Berard
NCT03716583 COMPLETED Melatonin Cream Against Acute Radiation Dermatitis in Patients With Early Breast Cancer
Dennis Bregner Zetner
NCT03795012 TERMINATED Trial With Eribulin or Eribulin+ Endocrine Therapy in Locally-recurrent or Metastatic Breast Cancer Patients
MedSIR
NCT03872505 WITHDRAWN Pre-operAtive Non-Anthracycline Chemotherapy, Durvalumab +/- RAdiation Therapy in Triple Negative Breast Cancer
Cedars-Sinai Medical Center
NCT03186937 TERMINATED A Window of Opportunity Study of Methionine Deprivation in Triple Negative Breast Cancer
University of Wisconsin, Madison
NCT03566485 TERMINATED Atezolizumab and Cobimetinib or Idasanutlin in Participants With Stage IV or Unresectable Recurrent Estrogen Receptor Positive Breast Cancer
Vanderbilt-Ingram Cancer Center
NCT03952325 TERMINATED Tesetaxel Plus 3 Different PD-(L)1 Inhibitors in Patients With Triple-Negative MBC and Tesetaxel Monotherapy in Patients With HER2-Negative MBC
Odonate Therapeutics, Inc.
NCT03858972 TERMINATED Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC
Odonate Therapeutics, Inc.
NCT02593227 COMPLETED Folate Receptor Alpha Peptide Vaccine With GM-CSF in Patients With Triple Negative Breast Cancer
Marker Therapeutics, Inc.
NCT04655183 WITHDRAWN Study of M4344 in Combination With Niraparib
EMD Serono Research & Development Institute, Inc.
NCT03113825 COMPLETED Study of AVB-620 in Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery
Avelas Biosciences, Inc.
NCT02505048 COMPLETED A Study to Assess the Efficacy of Rucaparib in Metastatic Breast Cancer Patients With a BRCAness Genomic Signature
UNICANCER
NCT03411161 COMPLETED S 81694 Plus Paclitaxel in Metastatic Breast Cancer
Institut de Recherches Internationales Servier
NCT03983395 TERMINATED Study of ISB 1302 (CD3 Bispecific Ab) in HER2-positive Metastatic Breast Cancer
Ichnos Sciences SA
NCT02909751 COMPLETED Tocotrienol in Combination With Neoadjuvant Chemotherapy for Women With Breast Cancer
Vejle Hospital
NCT02953860 COMPLETED Fulvestrant Plus Enzalutamide in ER+/Her2- Advanced Breast Cancer
University of Colorado, Denver
NCT02186015 COMPLETED Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D)
Loyola University
NCT02732119 COMPLETED Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.
Novartis Pharmaceuticals
NCT03051672 TERMINATED Phase II PEMBROLIZUMAB + PALLIATIVE RADIOTHERAPY IN BC
Dana-Farber Cancer Institute
NCT02569801 TERMINATED A Study of GDC-0810 Versus Fulvestrant in Postmenopausal Women With Advanced or Metastatic Breast Cancer Resistant to Aromatase Inhibitor (AI) Therapy
Genentech, Inc.
NCT02811497 COMPLETED Study of Azacitidine and Durvalumab in Advanced Solid Tumors
University Health Network, Toronto
NCT03248427 COMPLETED Neadjuvant Multi-agent Chemotherapy or Letrozole Plus Ribociclib in Luminal B/HER2-negative Breast Cancer.
SOLTI Breast Cancer Research Group
NCT02687490 COMPLETED Abraxane in Patients With Visceral Metastases Dominant Metastatic Breast Cancer
Fudan University
NCT03863301 WITHDRAWN MRI-guided Single Dose Preoperative Radiotherapy in Low-risk Breast Cancer
UMC Utrecht
NCT02924883 COMPLETED A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Participants With Human Epidermal Growth Factor-2 (HER2) Positive Locally Advanced or Metastatic Breast Cancer (BC) Who Received Prior Trastuzumab and Taxane Based Therapy
Hoffmann-La Roche
NCT02685059 COMPLETED Addition of PD-L1 Antibody MEDI4736 to a Taxane-anthracycline Chemotherapy in Triple Negative Breast Cancer
GBG Forschungs GmbH
NCT04166253 COMPLETED Protective Role of Vitamin D in Breast Cancer Patients Treated With Doxorubicin
Damanhour University
NCT02682693 COMPLETED Denosumab as an add-on Neoadjuvant Treatment (GeparX)
GBG Forschungs GmbH
NCT02362230 TERMINATED Evaluation of Icotinib in Metastatic Triple-negative Breast Cancer After Second-line Therapy
Sun Yat-sen University
NCT02725489 COMPLETED Pilot Study of Durvalumab and Vigil in Advanced Women's Cancers
Mary Crowley Medical Research Center
NCT02878057 COMPLETED Multicenter Phase II Study of Apatinib in Patients With Advanced Breast Cancer(CABC006)
Peking University Cancer Hospital & Institute
NCT02517593 COMPLETED Genetic Risk Estimation of Breast Cancer Prior to Preventive Medication Uptake
Mayo Clinic
NCT02308020 COMPLETED A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain
Eli Lilly and Company
NCT02447003 COMPLETED Study of Pembrolizumab (MK-3475) Monotherapy for Metastatic Triple-Negative Breast Cancer (MK-3475-086/KEYNOTE-086)
Merck Sharp & Dohme LLC
NCT02677714 TERMINATED 99mTc-rhAnnexin V-128 Imaging and Cardiotoxicity in Patients With Early Breast Cancer
Advanced Accelerator Applications
NCT04659551 COMPLETED Neoadjuvant Chemo-endocrine Therapy and Immunotherapy for Pre-menopausal Luminal B Breast Cancer Patients
Istituto Oncologico Veneto IRCCS
NCT02463032 COMPLETED Efficacy and Safety of GTx-024 in Patients With Estrogen Receptor (ER)+/Androgen Receptor (AR)+ Breast Cancer
GTx
NCT03535961 COMPLETED Apatinib Combined With Oral Etoposide in Metastatic HER2 Negative Breast Cancer
Chinese Academy of Medical Sciences
NCT03106077 COMPLETED Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast Cancer
M.D. Anderson Cancer Center
NCT02757651 COMPLETED KORTUC: Intra-tumoural Hydrogen Peroxide as a Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer in Terms of Toxicity and Tumour Response
Institute of Cancer Research, United Kingdom
NCT03819010 COMPLETED Neoadjuvant Letrozole and Palbociclib in Patients With Stage II-IIIB Breast Cancer, HR+, HER2 -
MedSIR
NCT03724253 TERMINATED [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)
Advanced Accelerator Applications
NCT03394287 COMPLETED A Trial of SHR-1210 (an Anti-PD-1 Antibody) in Combination With Apatinib in Patients With Advanced TNBC
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT03524261 WITHDRAWN Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Breast Cancer
Fuda Cancer Hospital, Guangzhou
NCT04426435 COMPLETED Effects a Honey Based Syrup on Blood Parameters in Patients With Breast Cancer
Shiraz University of Medical Sciences
NCT02997995 COMPLETED Durvalumab and Endocrine Therapy in ER+/Her2- Breast Cancer After CD8+ Infiltration Effective Immune-Attractant Exposure
UNICANCER
NCT04220476 WITHDRAWN CIMER: Combined Immunotherapies in Metastatic ER+ Breast Cancer
Weill Medical College of Cornell University
NCT02402764 COMPLETED Phase 2 Trial of Selinexor (KPT-330) for Metastatic Triple Negative Breast Cancer (TNBC)
H. Lee Moffitt Cancer Center and Research Institute
NCT03697551 TERMINATED Define the Optimal Uptake Time of 68Ga-OPS202 When Used as a PET (Positron Emission Tomography) Imaging Agent in Subjects With Newly Diagnosed Breast Cancer
Ipsen
NCT03241810 TERMINATED Phase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast Cancer
Elevation Oncology
NCT03430466 TERMINATED Anti PD-L1 Antibody + Anti CTLA-4 Antibody in Combination With Hormone Therapy in Patients With Hormone Receptor Positive HER2-negative Recurrent or Metastatic Breast Cancer
Kyoto Breast Cancer Research Network
NCT04496492 COMPLETED Preoperative Use of Tocotrienol From Annatto Bixa Orellana L. in Breast Cancer Patients: a Prospective Clinical Trial.
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
NCT02685111 TERMINATED Intermittent G-CSF in Patients With Breast Cancer Receiving Adjuvant Docetaxel, Doxorubicin, and Cyclophosphamide (TAC)
Asan Medical Center
NCT02581839 COMPLETED Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate
Case Comprehensive Cancer Center
NCT03393117 WITHDRAWN Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction
Case Comprehensive Cancer Center
NCT02547961 WITHDRAWN Chimeric Antigen Receptor-Modified T Cells for Breast Cancer
Fuda Cancer Hospital, Guangzhou
NCT02892734 TERMINATED Ipilimumab and Nivolumab in Treating Patients With Recurrent Stage IV HER2 Negative Inflammatory Breast Cancer
Northwestern University
NCT02362958 COMPLETED A Multi-Center Study of Lapatinib in Patients With Trastuzumab-refractory Metastatic Breast Cancer
Sun Yat-sen University
NCT02624700 TERMINATED 2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast Cancer
Virginia Commonwealth University
NCT04072718 COMPLETED Simultaneous Integrated Boost With Volumetric Arc Radiotherapy in Patients With Breast Cancer
Post Graduate Institute of Medical Education and Research, Chandigarh
NCT03183206 COMPLETED Safety and Efficiency of γδ T Cell Against Breast Cancer
Fuda Cancer Hospital, Guangzhou
NCT02753595 TERMINATED Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, High-Hyaluronan (HA) Metastatic Breast Cancer (MBC)
Eisai Inc.
NCT02628132 COMPLETED Study of Safety and Efficacy of Durvalumab in Combination With Paclitaxel in Metastatic Triple Negative Breast Cancer Patients
King Faisal Specialist Hospital & Research Center
NCT02544997 COMPLETED A Phase II, Single-Arm Trial of Poziotinib as Salvage Treatment in Patients With Metastatic Breast Cancer Who Has HER2 or EGFR Mutation or Activated AR or EGFR Pathway
Samsung Medical Center
NCT02462200 TERMINATED Shave Margins in Breast Conservation Therapy
Washington University School of Medicine
NCT02441946 COMPLETED A Neoadjuvant Study of Abemaciclib (LY2835219) in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer
Eli Lilly and Company
NCT04418089 COMPLETED Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Indonesia University
NCT04066790 TERMINATED Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer
Shanghai Jiao Tong University School of Medicine
NCT03065712 WITHDRAWN Test - Retest Reproducibility of 18F Fluoroestradiol (FES) PET
University of Texas Southwestern Medical Center
NCT03637868 WITHDRAWN Eribulin in Brain Metastases From HER2-negative Breast Cancer
Institut Paoli-Calmettes
NCT03400254 WITHDRAWN Gedatolisib, Hydroxychloroquine or the Combination for Prevention of Recurrent Breast Cancer ("GLACIER")
Abramson Cancer Center at Penn Medicine
NCT02774681 TERMINATED Palbociclib in Treating Patients With Metastatic HER-2 Positive Breast Cancer With Brain Metastasis
Northwestern University
NCT02455154 COMPLETED Traditional Chinese Medicine as Preventive Method for Osteoporosis Induced by Adjuvant Endocrine Therapy
Shanghai Jiao Tong University School of Medicine
NCT02713984 WITHDRAWN A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer
Zhi Yang
NCT01924351 WITHDRAWN HER2-positive Breast Cancer With Brain Metastasis (GCC 1345)
University of Maryland, Baltimore
NCT02789332 COMPLETED Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency
GBG Forschungs GmbH
NCT03763851 TERMINATED Cannabis Oil and Radiation Therapy for the Management of Pain
Tetra Bio-Pharma
NCT03323424 WITHDRAWN Phase II Trial Assessing the Efficacy of Immuno-Radiation Abscopal Effect in Patients With Metastatic Cancers
Institut de Cancérologie de la Loire
NCT02312934 COMPLETED Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study
Vanderbilt University Medical Center
NCT04224922 COMPLETED Phase II Study of Neoadjuvant Weekly Paclitaxel and Carboplatin Followed by Dose Dense Epirubicin and Cyclophosphamide in Stage II and III Triple Negative Breast Cancer
AZ-VUB
NCT02455453 COMPLETED Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography
Washington University School of Medicine
NCT03611985 WITHDRAWN Phase I/IIa Study of Pharmacokinetics and Safety of Epidiferphane™ and Taxanes in Breast Cancer Patients
University of Florida
NCT02541370 COMPLETED Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
Chinese PLA General Hospital
NCT03300843 TERMINATED Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer
National Cancer Institute (NCI)
NCT02538471 TERMINATED LY2157299 Monohydrate (LY2157299) and Radiotherapy in Metastatic Breast Cancer
Weill Medical College of Cornell University
NCT02697032 COMPLETED FDHT PET and Bicalutamide in Metastatic Breast Cancer
University Medical Center Groningen
NCT03072992 COMPLETED "Curcumin" in Combination With Chemotherapy in Advanced Breast Cancer
National Center of Oncology, Armenia
NCT01952054 TERMINATED Denosumab for Breast Cancer With Bone Mets
M.D. Anderson Cancer Center
NCT02853071 WITHDRAWN Efficacy and Safety of Estracyt® in Metastatic Breast Cancer
Centre Hospitalier Universitaire de Besancon
NCT03185871 WITHDRAWN Celecoxib Window of Opportunity Trial to Assess Tumor and Stroma Responses
University of Wisconsin, Madison
NCT02538432 WITHDRAWN Phase II Trial of EP4 Receptor Antagonist, AAT-007 (RQ-07; CJ-023,423) in Advanced Solid Tumors
University of Maryland, Baltimore
NCT02628613 COMPLETED Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations
Fudan University
NCT02839668 COMPLETED The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC)
Iuliu Hatieganu University of Medicine and Pharmacy
NCT02950480 TERMINATED Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial
University of California, San Francisco
NCT01740323 COMPLETED Phase II Study of Curcumin vs Placebo for Chemotherapy-Treated Breast Cancer Patients Undergoing Radiotherapy
Andrew H Miller
NCT02844335 COMPLETED Combination of Cryosurgery and NK Immunotherapy for Advanced Breast Cancer
Fuda Cancer Hospital, Guangzhou
NCT02843126 COMPLETED Combination of Trastuzumab and NK Immunotherapy for Recurrent Breast Cancer
Fuda Cancer Hospital, Guangzhou
NCT02598310 TERMINATED Neoadjuvant Nab-PTX and Trastuzumab for ER Negative and HER2 Positive Breast Cancer
Osaka Medical College
NCT02525718 COMPLETED Selective Intraoperative Administration of Local Anesthesia in Breast Reconstruction
Northwestern University
NCT03007992 COMPLETED Metronomic Treatment With Daily Oral Vinorelbine as First-line Chemotherapy in Patients With Advanced/Metastatic Hormone Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Breast Cancer
Johannes Gutenberg University Mainz
NCT03794596 WITHDRAWN A Proof of Concept, Window Trial of the IMmunological Effects of AveLumab and Aspirin in Triple-Negative Breast Cancer
The Christie NHS Foundation Trust
NCT03558490 COMPLETED A Study to Assess the Feasibility of an E-Health System (ZEMY) Designed to Manage Symptoms in Participants With Breast Cancer Under Anti-Cancer Treatment
Hoffmann-La Roche
NCT02389764 TERMINATED Nintedanib For HER2-Negative Metastatic Inflammatory Breast Cancer (MIBC)
M.D. Anderson Cancer Center
NCT00960544 WITHDRAWN Correlation of Genomic Variation in Enzymes Responsible for Metabolism of Capecitabine With Drug Metabolism
M.D. Anderson Cancer Center
NCT02674204 TERMINATED STOP Heart Disease in Breast Cancer Survivors Trial
Cedars-Sinai Medical Center
NCT03644589 WITHDRAWN Effect of Pembrolizumab and Cisplatin on Metastatic, Locally Recurrent or Inoperable Triple-Negative Breast Cancer
University of Washington
NCT03058939 WITHDRAWN Assessing the Response Rate of Neo-adjuvant Paclitaxel (Taxol) in Nigerian Women With Breast Cancer
University of Chicago
NCT02658084 TERMINATED Vinorelbine With Trastuzumab Emtansine in Pre-Treated HER2-Positive Metastatic Breast Cancer
University of Miami
NCT02723877 COMPLETED PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)
PIQUR Therapeutics AG
NCT02580448 COMPLETED CYP17 Lyase and Androgen Receptor Inhibitor Treatment With Seviteronel Trial (INO-VT-464-006; NCT02580448)
Innocrin Pharmaceutical
NCT02275403 COMPLETED Standard Care Alone or With Acupuncture for CIPN in Breast Cancer and Multiple Myeloma
The Christie NHS Foundation Trust
NCT02856503 WITHDRAWN Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors
Eli Avisar
NCT02599194 COMPLETED 18F-FSPG PET/CT for Cancer Patients on Therapy
Andrei Iagaru
NCT02403271 COMPLETED A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors
Pharmacyclics LLC.
NCT03070002 TERMINATED Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cells
Northwestern University
NCT03405168 COMPLETED Routine Therapy Plus Moxifloxacin in Advanced Breast Cancer
Sun Yat-sen University
NCT02481050 COMPLETED Study to Evaluate the Efficacy and Safety of Eribulin Mesylate Administered Biweekly (Q2W) for Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Metastatic Breast Cancer
Eisai Inc.
NCT02347163 TERMINATED Pre-operative Zoledronate in Triple Negative Breast Cancer
Mario Negri Institute for Pharmacological Research
NCT02669914 TERMINATED MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors
Washington University School of Medicine
NCT02650193 COMPLETED A Study Of The Safety And Effects Of One Or More Doses Of HSP-130 Injected Under The Skin In Women With Breast Cancer That Has Not Spread To Distant Sites In The Body.
Pfizer
NCT02301988 COMPLETED A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer
Genentech, Inc.
NCT02988648 WITHDRAWN A Clinical Trial Evaluating the Safety and Clinical Activity of Radioiodide (131I-) as a Novel Targeted Therapy for Metastatic Breast Cancer That Overexpresses Functional Na/I Symporter
Yale University
NCT03377101 WITHDRAWN Fulvestrant and Palbociclib With or Without Copanlisib in Treating Patients With Hormone Receptor Positive, HER2 Negative, Stage IV Breast Cancer
National Cancer Institute (NCI)
NCT03326258 WITHDRAWN Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT03576521 COMPLETED Evaluation of Ocoxin®-Viusid® in Breast Cancer
Catalysis SL
NCT03575520 COMPLETED Safety and Efficacy of Pegteograstim in Korean Breast Cancer Patients
Yonsei University
NCT03407430 TERMINATED Trial of Pregabalin for Granulocyte Colony-stimulating Factor (GCSF)-Induced Bone Pain
UNC Lineberger Comprehensive Cancer Center
NCT02365714 TERMINATED CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI)
Georgetown University
NCT02831530 COMPLETED Randomized Short-term Pre-surgical Study to Assess the Effects of Abemaciclib (LY2835219) in Early Breast Cancer Patients
Gustave Roussy, Cancer Campus, Grand Paris
NCT02596867 TERMINATED Neoadjuvant Propanolol in Breast Cancer
Texas Tech University Health Sciences Center, El Paso
NCT02664103 COMPLETED Study of Capecitabine and Cyclophosphamide Administered as a Single Pill in Patients With Advanced Breast Cancer
Sanofi
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